TY  - JOUR
AU  - Cabreira, Verónica
AU  - Alty, Jane
AU  - Antić, Sonja
AU  - Araújo, Rui
AU  - Aybek, Selma
AU  - Ball, Harriet A.
AU  - Baslet, Gaston
AU  - Bhome, Rohan
AU  - Coebergh, Jan
AU  - Dubois, Bruno
AU  - Edwards, Mark
AU  - Filipović, Saša
AU  - Frederiksen, Kristian Steen
AU  - Harbo, Thomas
AU  - Hayhow, Bradleigh
AU  - Howard, Robert
AU  - Huntley, Jonathan
AU  - Isaacs, Jeremy
AU  - LaFrance Jr., William Curt
AU  - Larner, Andrew J.
AU  - Di Lorenzo, Francesco
AU  - Main, James
AU  - Mallam, Elizabeth
AU  - Marra, Camillo
AU  - Massano, João
AU  - McGrath, Emer R.
AU  - McWhirter, Laura
AU  - Moreira, Isabel Portela
AU  - Nobili, Flavio
AU  - Pennington, Catherine
AU  - Tábuas-Pereira, Miguel
AU  - Perez, David L.
AU  - Popkirov, Stoyan
AU  - Rayment, Dane
AU  - Rossor, Martin
AU  - Russo, Mirella
AU  - Santana, Isabel
AU  - Schott, Jonathan
AU  - Scott, Emmi P.
AU  - Taipa, Ricardo
AU  - Tinazzi, Michele
AU  - Tomić, Svetlana
AU  - Toniolo, Sofia
AU  - Tørring, Caroline Winther
AU  - Wilkinson, Tim
AU  - Frostholm, Lisbeth
AU  - Stone, Jon
AU  - Carson, Alan
PY  - 2024
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1481
AB  - Background: Current proposed criteria for functional cognitive disorder (FCD) have not been externally validated. We sought to analyse the current perspectives of cognitive specialists in the diagnosis and management of FCD in comparison with neurodegenerative conditions. Methods: International experts in cognitive disorders were invited to assess seven illustrative clinical vignettes containing history and bedside characteristics alone. Participants assigned a probable diagnosis and selected the appropriate investigation and treatment. Qualitative, quantitative and inter-rater agreement analyses were undertaken. Results: Eighteen diagnostic terminologies were assigned by 45 cognitive experts from 12 countries with a median of 13 years of experience, across the seven scenarios. Accurate discrimination between FCD and neurodegeneration was observed, independently of background and years of experience: 100% of the neurodegenerative vignettes were correctly classified and 75%–88% of the FCD diagnoses were attributed to non-neurodegenerative causes. There was <50% agreement in the terminology used for FCD, in comparison with 87%–92% agreement for neurodegenerative syndromes. Blood tests and neuropsychological evaluation were the leading diagnostic modalities for FCD. Diagnostic communication, psychotherapy and psychiatry referral were the main suggested management strategies in FCD. Conclusions: Our study demonstrates the feasibility of distinguishing between FCD and neurodegeneration based on relevant patient characteristics and history details. These characteristics need further validation and operationalisation. Heterogeneous labelling and framing pose clinical and research challenges reflecting a lack of agreement in the field. Careful consideration of FCD diagnosis is advised, particularly in the presence of comorbidities. This study informs future research on diagnostic tools and evidence-based interventions.
PB  - Wiley-Blackwell
T2  - European Journal of Neurology
T2  - European Journal of Neurology
T1  - Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study
IS  - n/a
SP  - e16318
VL  - n/a
DO  - 10.1111/ene.16318
ER  - 

@article{
author = "Cabreira, Verónica and Alty, Jane and Antić, Sonja and Araújo, Rui and Aybek, Selma and Ball, Harriet A. and Baslet, Gaston and Bhome, Rohan and Coebergh, Jan and Dubois, Bruno and Edwards, Mark and Filipović, Saša and Frederiksen, Kristian Steen and Harbo, Thomas and Hayhow, Bradleigh and Howard, Robert and Huntley, Jonathan and Isaacs, Jeremy and LaFrance Jr., William Curt and Larner, Andrew J. and Di Lorenzo, Francesco and Main, James and Mallam, Elizabeth and Marra, Camillo and Massano, João and McGrath, Emer R. and McWhirter, Laura and Moreira, Isabel Portela and Nobili, Flavio and Pennington, Catherine and Tábuas-Pereira, Miguel and Perez, David L. and Popkirov, Stoyan and Rayment, Dane and Rossor, Martin and Russo, Mirella and Santana, Isabel and Schott, Jonathan and Scott, Emmi P. and Taipa, Ricardo and Tinazzi, Michele and Tomić, Svetlana and Toniolo, Sofia and Tørring, Caroline Winther and Wilkinson, Tim and Frostholm, Lisbeth and Stone, Jon and Carson, Alan",
year = "2024",
abstract = "Background: Current proposed criteria for functional cognitive disorder (FCD) have not been externally validated. We sought to analyse the current perspectives of cognitive specialists in the diagnosis and management of FCD in comparison with neurodegenerative conditions. Methods: International experts in cognitive disorders were invited to assess seven illustrative clinical vignettes containing history and bedside characteristics alone. Participants assigned a probable diagnosis and selected the appropriate investigation and treatment. Qualitative, quantitative and inter-rater agreement analyses were undertaken. Results: Eighteen diagnostic terminologies were assigned by 45 cognitive experts from 12 countries with a median of 13 years of experience, across the seven scenarios. Accurate discrimination between FCD and neurodegeneration was observed, independently of background and years of experience: 100% of the neurodegenerative vignettes were correctly classified and 75%–88% of the FCD diagnoses were attributed to non-neurodegenerative causes. There was <50% agreement in the terminology used for FCD, in comparison with 87%–92% agreement for neurodegenerative syndromes. Blood tests and neuropsychological evaluation were the leading diagnostic modalities for FCD. Diagnostic communication, psychotherapy and psychiatry referral were the main suggested management strategies in FCD. Conclusions: Our study demonstrates the feasibility of distinguishing between FCD and neurodegeneration based on relevant patient characteristics and history details. These characteristics need further validation and operationalisation. Heterogeneous labelling and framing pose clinical and research challenges reflecting a lack of agreement in the field. Careful consideration of FCD diagnosis is advised, particularly in the presence of comorbidities. This study informs future research on diagnostic tools and evidence-based interventions.",
publisher = "Wiley-Blackwell",
journal = "European Journal of Neurology, European Journal of Neurology",
title = "Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study",
number = "n/a",
pages = "e16318",
volume = "n/a",
doi = "10.1111/ene.16318"
}

Cabreira, V., Alty, J., Antić, S., Araújo, R., Aybek, S., Ball, H. A., Baslet, G., Bhome, R., Coebergh, J., Dubois, B., Edwards, M., Filipović, S., Frederiksen, K. S., Harbo, T., Hayhow, B., Howard, R., Huntley, J., Isaacs, J., LaFrance Jr., W. C., Larner, A. J., Di Lorenzo, F., Main, J., Mallam, E., Marra, C., Massano, J., McGrath, E. R., McWhirter, L., Moreira, I. P., Nobili, F., Pennington, C., Tábuas-Pereira, M., Perez, D. L., Popkirov, S., Rayment, D., Rossor, M., Russo, M., Santana, I., Schott, J., Scott, E. P., Taipa, R., Tinazzi, M., Tomić, S., Toniolo, S., Tørring, C. W., Wilkinson, T., Frostholm, L., Stone, J.,& Carson, A.. (2024). Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study. in European Journal of Neurology
Wiley-Blackwell., n/a(n/a), e16318.
https://doi.org/10.1111/ene.16318

Cabreira V, Alty J, Antić S, Araújo R, Aybek S, Ball HA, Baslet G, Bhome R, Coebergh J, Dubois B, Edwards M, Filipović S, Frederiksen KS, Harbo T, Hayhow B, Howard R, Huntley J, Isaacs J, LaFrance Jr. WC, Larner AJ, Di Lorenzo F, Main J, Mallam E, Marra C, Massano J, McGrath ER, McWhirter L, Moreira IP, Nobili F, Pennington C, Tábuas-Pereira M, Perez DL, Popkirov S, Rayment D, Rossor M, Russo M, Santana I, Schott J, Scott EP, Taipa R, Tinazzi M, Tomić S, Toniolo S, Tørring CW, Wilkinson T, Frostholm L, Stone J, Carson A. Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study. in European Journal of Neurology. 2024;n/a(n/a):e16318.
doi:10.1111/ene.16318 .

Cabreira, Verónica, Alty, Jane, Antić, Sonja, Araújo, Rui, Aybek, Selma, Ball, Harriet A., Baslet, Gaston, Bhome, Rohan, Coebergh, Jan, Dubois, Bruno, Edwards, Mark, Filipović, Saša, Frederiksen, Kristian Steen, Harbo, Thomas, Hayhow, Bradleigh, Howard, Robert, Huntley, Jonathan, Isaacs, Jeremy, LaFrance Jr., William Curt, Larner, Andrew J., Di Lorenzo, Francesco, Main, James, Mallam, Elizabeth, Marra, Camillo, Massano, João, McGrath, Emer R., McWhirter, Laura, Moreira, Isabel Portela, Nobili, Flavio, Pennington, Catherine, Tábuas-Pereira, Miguel, Perez, David L., Popkirov, Stoyan, Rayment, Dane, Rossor, Martin, Russo, Mirella, Santana, Isabel, Schott, Jonathan, Scott, Emmi P., Taipa, Ricardo, Tinazzi, Michele, Tomić, Svetlana, Toniolo, Sofia, Tørring, Caroline Winther, Wilkinson, Tim, Frostholm, Lisbeth, Stone, Jon, Carson, Alan, "Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study" in European Journal of Neurology, n/a, no. n/a (2024):e16318,
https://doi.org/10.1111/ene.16318 . .

TY  - JOUR
AU  - Antal, Andrea
AU  - Ganho-Ávila, Ana
AU  - Assecondi, Sara
AU  - Barbour, Tracy
AU  - Bjekić, Jovana
AU  - Blumberger, Daniel M.
AU  - Bolognini, Nadia
AU  - Brunelin, Jerome
AU  - Chanes, Lorena
AU  - Dale, Matthew
AU  - Dubbioso, Raffaele
AU  - D'Urso, Giordano
AU  - Filipčić, Igor
AU  - Filipović, Saša
AU  - Hirnstein, Marco
AU  - Konings, Femke
AU  - Langguth, Berthold
AU  - Leocani, Letizia
AU  - Sorkhabi, Majid Memarian
AU  - Mulder, Marc
AU  - Nikander, Mika
AU  - Nowak, Rafal
AU  - Oliviero, Antonio
AU  - Onarheim, Balder
AU  - O'Shea, Jacinta
AU  - Pallanti, Stefano
AU  - Rachid, Fady
AU  - Rajão-Saraiva, Joana
AU  - Rossi, Simone
AU  - Sack, Alexander T.
AU  - Sauvaget, Anne
AU  - van der Scheer, Rik
AU  - Schellhorn, Klaus
AU  - Soria-Frisch, Aureli
AU  - Szekely, David
AU  - Tankisi, Hatice
AU  - CJ. Taylor, Paul
AU  - Tendolkar, Indira
AU  - Uusitalo, Susanne
AU  - Baeken, Chris
PY  - 2024
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1479
AB  - A significant amount of European basic and clinical neuroscience research includes the use of transcranial magnetic stimulation (TMS) and low intensity transcranial electrical stimulation (tES), mainly transcranial direct current stimulation (tDCS). Two recent changes in the EU regulations, the introduction of the Medical Device Regulation (MDR) (2017/745) and the Annex XVI have caused significant problems and confusions in the brain stimulation field. The negative consequences of the MDR for non-invasive brain stimulation (NIBS) have been largely overlooked and until today, have not been consequently addressed by National Competent Authorities, local ethical committees, politicians and by the scientific communities. In addition, a rushed bureaucratic decision led to seemingly wrong classification of NIBS products without an intended medical purpose into the same risk group III as invasive stimulators. Overregulation is detrimental for any research and for future developments, therefore researchers, clinicians, industry, patient representatives and an ethicist were invited to contribute to this document with the aim of starting a constructive dialogue and enacting positive changes in the regulatory environment.
PB  - Elsevier
T2  - Clinical Neurophysiology
T1  - The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper
DO  - 10.1016/j.clinph.2024.03.039
ER  - 

@article{
author = "Antal, Andrea and Ganho-Ávila, Ana and Assecondi, Sara and Barbour, Tracy and Bjekić, Jovana and Blumberger, Daniel M. and Bolognini, Nadia and Brunelin, Jerome and Chanes, Lorena and Dale, Matthew and Dubbioso, Raffaele and D'Urso, Giordano and Filipčić, Igor and Filipović, Saša and Hirnstein, Marco and Konings, Femke and Langguth, Berthold and Leocani, Letizia and Sorkhabi, Majid Memarian and Mulder, Marc and Nikander, Mika and Nowak, Rafal and Oliviero, Antonio and Onarheim, Balder and O'Shea, Jacinta and Pallanti, Stefano and Rachid, Fady and Rajão-Saraiva, Joana and Rossi, Simone and Sack, Alexander T. and Sauvaget, Anne and van der Scheer, Rik and Schellhorn, Klaus and Soria-Frisch, Aureli and Szekely, David and Tankisi, Hatice and CJ. Taylor, Paul and Tendolkar, Indira and Uusitalo, Susanne and Baeken, Chris",
year = "2024",
abstract = "A significant amount of European basic and clinical neuroscience research includes the use of transcranial magnetic stimulation (TMS) and low intensity transcranial electrical stimulation (tES), mainly transcranial direct current stimulation (tDCS). Two recent changes in the EU regulations, the introduction of the Medical Device Regulation (MDR) (2017/745) and the Annex XVI have caused significant problems and confusions in the brain stimulation field. The negative consequences of the MDR for non-invasive brain stimulation (NIBS) have been largely overlooked and until today, have not been consequently addressed by National Competent Authorities, local ethical committees, politicians and by the scientific communities. In addition, a rushed bureaucratic decision led to seemingly wrong classification of NIBS products without an intended medical purpose into the same risk group III as invasive stimulators. Overregulation is detrimental for any research and for future developments, therefore researchers, clinicians, industry, patient representatives and an ethicist were invited to contribute to this document with the aim of starting a constructive dialogue and enacting positive changes in the regulatory environment.",
publisher = "Elsevier",
journal = "Clinical Neurophysiology",
title = "The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper",
doi = "10.1016/j.clinph.2024.03.039"
}

Antal, A., Ganho-Ávila, A., Assecondi, S., Barbour, T., Bjekić, J., Blumberger, D. M., Bolognini, N., Brunelin, J., Chanes, L., Dale, M., Dubbioso, R., D'Urso, G., Filipčić, I., Filipović, S., Hirnstein, M., Konings, F., Langguth, B., Leocani, L., Sorkhabi, M. M., Mulder, M., Nikander, M., Nowak, R., Oliviero, A., Onarheim, B., O'Shea, J., Pallanti, S., Rachid, F., Rajão-Saraiva, J., Rossi, S., Sack, A. T., Sauvaget, A., van der Scheer, R., Schellhorn, K., Soria-Frisch, A., Szekely, D., Tankisi, H., CJ. Taylor, P., Tendolkar, I., Uusitalo, S.,& Baeken, C.. (2024). The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper. in Clinical Neurophysiology
Elsevier..
https://doi.org/10.1016/j.clinph.2024.03.039

Antal A, Ganho-Ávila A, Assecondi S, Barbour T, Bjekić J, Blumberger DM, Bolognini N, Brunelin J, Chanes L, Dale M, Dubbioso R, D'Urso G, Filipčić I, Filipović S, Hirnstein M, Konings F, Langguth B, Leocani L, Sorkhabi MM, Mulder M, Nikander M, Nowak R, Oliviero A, Onarheim B, O'Shea J, Pallanti S, Rachid F, Rajão-Saraiva J, Rossi S, Sack AT, Sauvaget A, van der Scheer R, Schellhorn K, Soria-Frisch A, Szekely D, Tankisi H, CJ. Taylor P, Tendolkar I, Uusitalo S, Baeken C. The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper. in Clinical Neurophysiology. 2024;.
doi:10.1016/j.clinph.2024.03.039 .

Antal, Andrea, Ganho-Ávila, Ana, Assecondi, Sara, Barbour, Tracy, Bjekić, Jovana, Blumberger, Daniel M., Bolognini, Nadia, Brunelin, Jerome, Chanes, Lorena, Dale, Matthew, Dubbioso, Raffaele, D'Urso, Giordano, Filipčić, Igor, Filipović, Saša, Hirnstein, Marco, Konings, Femke, Langguth, Berthold, Leocani, Letizia, Sorkhabi, Majid Memarian, Mulder, Marc, Nikander, Mika, Nowak, Rafal, Oliviero, Antonio, Onarheim, Balder, O'Shea, Jacinta, Pallanti, Stefano, Rachid, Fady, Rajão-Saraiva, Joana, Rossi, Simone, Sack, Alexander T., Sauvaget, Anne, van der Scheer, Rik, Schellhorn, Klaus, Soria-Frisch, Aureli, Szekely, David, Tankisi, Hatice, CJ. Taylor, Paul, Tendolkar, Indira, Uusitalo, Susanne, Baeken, Chris, "The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper" in Clinical Neurophysiology (2024),
https://doi.org/10.1016/j.clinph.2024.03.039 . .

TY  - JOUR
AU  - Rakuša, Martin
AU  - Moro, Elena
AU  - Akhvlediani, Tamar
AU  - Bereczki, Daniel
AU  - Bodini, Benedetta
AU  - Cavallieri, Francesco
AU  - Fanciulli, Alessandra
AU  - Filipović, Saša
AU  - Guekht, Alla
AU  - Helbok, Raimund
AU  - Hochmeister, Sonja
AU  - Martinelli Boneschi, Filippo
AU  - Özturk, Serefnur
AU  - Priori, Alberto
AU  - Romoli, Michele
AU  - Willekens, Barbara
AU  - Zedde, Marialuisa
AU  - Sellner, Johann
PY  - 2024
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1398
AB  - Background and Purpose The COVID-19 pandemic has significantly impacted health systems worldwide. Here, we assessed the pandemic's impact on clinical service, curricular training, and financial burden from a neurological viewpoint during the enforced lockdown periods and the assumed recovery by 2023. Methods An online 18-item survey was conducted by the European Academy of Neurology (EAN) NeuroCOVID-19 Task Force among the EAN community. The survey was online between February and March 2023. Questions related to general, demographic, clinical, work, education, and economic aspects. Results We collected 430 responses from 79 countries. Most health care professionals were aged 35–44 years, with >15 years of work experience. The key findings of their observations were as follows. (i) Clinical services were cut back in all neurological subspecialties during the most restrictive COVID-19 lockdown period. The most affected neurological subspecialties were services for patients with dementia, and neuromuscular and movement disorders. The levels of reduction and the pace of recovery were distinct for acute emergencies and in- and outpatient care. Recovery was slow for sleep medicine, autonomic nervous system disorders, neurorehabilitation, and dementia care. (ii) Student and residency rotations and grand rounds were reorganized, and congresses were converted into a virtual format. Conferences are partly maintained in a hybrid format. (iii) Affordability of neurological care and medication shortage are emerging issues. Conclusions Recovery of neurological services up to spring 2023 has been incomplete following substantial disruption of neurological care, medical education, and health economics in the wake of the COVID-19 pandemic. The continued limitations for the delivery of neurological care threaten brain health and call for action on a global scale.
PB  - Wiley-Blackwell
T2  - European Journal of Neurology
T1  - The COVID-19 pandemic and neurology: A survey on previous and continued restrictions for clinical practice, curricular training, and health economics
IS  - 3
SP  - e16168
VL  - 31
DO  - 10.1111/ene.16168
ER  - 

@article{
author = "Rakuša, Martin and Moro, Elena and Akhvlediani, Tamar and Bereczki, Daniel and Bodini, Benedetta and Cavallieri, Francesco and Fanciulli, Alessandra and Filipović, Saša and Guekht, Alla and Helbok, Raimund and Hochmeister, Sonja and Martinelli Boneschi, Filippo and Özturk, Serefnur and Priori, Alberto and Romoli, Michele and Willekens, Barbara and Zedde, Marialuisa and Sellner, Johann",
year = "2024",
abstract = "Background and Purpose The COVID-19 pandemic has significantly impacted health systems worldwide. Here, we assessed the pandemic's impact on clinical service, curricular training, and financial burden from a neurological viewpoint during the enforced lockdown periods and the assumed recovery by 2023. Methods An online 18-item survey was conducted by the European Academy of Neurology (EAN) NeuroCOVID-19 Task Force among the EAN community. The survey was online between February and March 2023. Questions related to general, demographic, clinical, work, education, and economic aspects. Results We collected 430 responses from 79 countries. Most health care professionals were aged 35–44 years, with >15 years of work experience. The key findings of their observations were as follows. (i) Clinical services were cut back in all neurological subspecialties during the most restrictive COVID-19 lockdown period. The most affected neurological subspecialties were services for patients with dementia, and neuromuscular and movement disorders. The levels of reduction and the pace of recovery were distinct for acute emergencies and in- and outpatient care. Recovery was slow for sleep medicine, autonomic nervous system disorders, neurorehabilitation, and dementia care. (ii) Student and residency rotations and grand rounds were reorganized, and congresses were converted into a virtual format. Conferences are partly maintained in a hybrid format. (iii) Affordability of neurological care and medication shortage are emerging issues. Conclusions Recovery of neurological services up to spring 2023 has been incomplete following substantial disruption of neurological care, medical education, and health economics in the wake of the COVID-19 pandemic. The continued limitations for the delivery of neurological care threaten brain health and call for action on a global scale.",
publisher = "Wiley-Blackwell",
journal = "European Journal of Neurology",
title = "The COVID-19 pandemic and neurology: A survey on previous and continued restrictions for clinical practice, curricular training, and health economics",
number = "3",
pages = "e16168",
volume = "31",
doi = "10.1111/ene.16168"
}

Rakuša, M., Moro, E., Akhvlediani, T., Bereczki, D., Bodini, B., Cavallieri, F., Fanciulli, A., Filipović, S., Guekht, A., Helbok, R., Hochmeister, S., Martinelli Boneschi, F., Özturk, S., Priori, A., Romoli, M., Willekens, B., Zedde, M.,& Sellner, J.. (2024). The COVID-19 pandemic and neurology: A survey on previous and continued restrictions for clinical practice, curricular training, and health economics. in European Journal of Neurology
Wiley-Blackwell., 31(3), e16168.
https://doi.org/10.1111/ene.16168

Rakuša M, Moro E, Akhvlediani T, Bereczki D, Bodini B, Cavallieri F, Fanciulli A, Filipović S, Guekht A, Helbok R, Hochmeister S, Martinelli Boneschi F, Özturk S, Priori A, Romoli M, Willekens B, Zedde M, Sellner J. The COVID-19 pandemic and neurology: A survey on previous and continued restrictions for clinical practice, curricular training, and health economics. in European Journal of Neurology. 2024;31(3):e16168.
doi:10.1111/ene.16168 .

Rakuša, Martin, Moro, Elena, Akhvlediani, Tamar, Bereczki, Daniel, Bodini, Benedetta, Cavallieri, Francesco, Fanciulli, Alessandra, Filipović, Saša, Guekht, Alla, Helbok, Raimund, Hochmeister, Sonja, Martinelli Boneschi, Filippo, Özturk, Serefnur, Priori, Alberto, Romoli, Michele, Willekens, Barbara, Zedde, Marialuisa, Sellner, Johann, "The COVID-19 pandemic and neurology: A survey on previous and continued restrictions for clinical practice, curricular training, and health economics" in European Journal of Neurology, 31, no. 3 (2024):e16168,
https://doi.org/10.1111/ene.16168 . .

TY  - JOUR
AU  - Rodriguez-Porcel, Federico
AU  - Sarva, Harini
AU  - Joutsa, Juho
AU  - Falup-Pecurariu, Cristian
AU  - Wagle Shukla, Aparna
AU  - Mehanna, Raja
AU  - Śmiłowska, Katarzyna
AU  - Lanza, Giuseppe
AU  - Filipović, Saša
AU  - Shalash, Ali
AU  - Ferris, Margaret
AU  - Jankovic, Joseph
AU  - Espay, Alberto J.
AU  - Pandey, Sanjay
PY  - 2024
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1459
AB  - Background: Post-stroke movement disorders (PSMD) encompass a wide array of presentations, which vary in mode of onset, phenomenology, response to treatment, and natural history. There are no evidence-based guidelines on the diagnosis and treatment of PSMD. Objectives: To survey current opinions and practices on the diagnosis and treatment of PSMD. Methods: A survey was developed by the PSMD Study Group, commissioned by the International Parkinson's and Movement Disorders Society (MDS). The survey, distributed to all members, yielded a total of 529 responses, 395 (74.7%) of which came from clinicians with experience with PSMD. Results: Parkinsonism (68%), hemiballismus/hemichorea (61%), tremor (58%), and dystonia (54%) were by far the most commonly endorsed presentation of PSMD, although this varied by region. Basal ganglia stroke (76% of responders), symptoms contralateral to stroke (75%), and a temporal relationship (59%) were considered important factors for the diagnosis of PSMD. Oral medication use depended on the phenomenology of the PSMD. Almost 50% of respondents considered deep brain stimulation and ablative surgeries as options for treatment. The lack of guidelines for the diagnosis and treatment was considered the most important gap to address. Conclusions: Regionally varying opinions and practices on PSMD highlight gaps in (and mistranslation of) epidemiologic and therapeutic knowledge. Multicenter registries and prospective community-based studies are needed for the creation of evidence-based guidelines to inform the diagnosis and treatment of patients with PSMD.
PB  - Elsevier
T2  - Journal of the Neurological Sciences
T2  - Journal of the Neurological Sciences
T1  - Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members
SP  - 122925
VL  - 458
DO  - 10.1016/j.jns.2024.122925
ER  - 

@article{
author = "Rodriguez-Porcel, Federico and Sarva, Harini and Joutsa, Juho and Falup-Pecurariu, Cristian and Wagle Shukla, Aparna and Mehanna, Raja and Śmiłowska, Katarzyna and Lanza, Giuseppe and Filipović, Saša and Shalash, Ali and Ferris, Margaret and Jankovic, Joseph and Espay, Alberto J. and Pandey, Sanjay",
year = "2024",
abstract = "Background: Post-stroke movement disorders (PSMD) encompass a wide array of presentations, which vary in mode of onset, phenomenology, response to treatment, and natural history. There are no evidence-based guidelines on the diagnosis and treatment of PSMD. Objectives: To survey current opinions and practices on the diagnosis and treatment of PSMD. Methods: A survey was developed by the PSMD Study Group, commissioned by the International Parkinson's and Movement Disorders Society (MDS). The survey, distributed to all members, yielded a total of 529 responses, 395 (74.7%) of which came from clinicians with experience with PSMD. Results: Parkinsonism (68%), hemiballismus/hemichorea (61%), tremor (58%), and dystonia (54%) were by far the most commonly endorsed presentation of PSMD, although this varied by region. Basal ganglia stroke (76% of responders), symptoms contralateral to stroke (75%), and a temporal relationship (59%) were considered important factors for the diagnosis of PSMD. Oral medication use depended on the phenomenology of the PSMD. Almost 50% of respondents considered deep brain stimulation and ablative surgeries as options for treatment. The lack of guidelines for the diagnosis and treatment was considered the most important gap to address. Conclusions: Regionally varying opinions and practices on PSMD highlight gaps in (and mistranslation of) epidemiologic and therapeutic knowledge. Multicenter registries and prospective community-based studies are needed for the creation of evidence-based guidelines to inform the diagnosis and treatment of patients with PSMD.",
publisher = "Elsevier",
journal = "Journal of the Neurological Sciences, Journal of the Neurological Sciences",
title = "Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members",
pages = "122925",
volume = "458",
doi = "10.1016/j.jns.2024.122925"
}

Rodriguez-Porcel, F., Sarva, H., Joutsa, J., Falup-Pecurariu, C., Wagle Shukla, A., Mehanna, R., Śmiłowska, K., Lanza, G., Filipović, S., Shalash, A., Ferris, M., Jankovic, J., Espay, A. J.,& Pandey, S.. (2024). Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members. in Journal of the Neurological Sciences
Elsevier., 458, 122925.
https://doi.org/10.1016/j.jns.2024.122925

Rodriguez-Porcel F, Sarva H, Joutsa J, Falup-Pecurariu C, Wagle Shukla A, Mehanna R, Śmiłowska K, Lanza G, Filipović S, Shalash A, Ferris M, Jankovic J, Espay AJ, Pandey S. Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members. in Journal of the Neurological Sciences. 2024;458:122925.
doi:10.1016/j.jns.2024.122925 .

Rodriguez-Porcel, Federico, Sarva, Harini, Joutsa, Juho, Falup-Pecurariu, Cristian, Wagle Shukla, Aparna, Mehanna, Raja, Śmiłowska, Katarzyna, Lanza, Giuseppe, Filipović, Saša, Shalash, Ali, Ferris, Margaret, Jankovic, Joseph, Espay, Alberto J., Pandey, Sanjay, "Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members" in Journal of the Neurological Sciences, 458 (2024):122925,
https://doi.org/10.1016/j.jns.2024.122925 . .

TY  - JOUR
AU  - Bjekić, Jovana
AU  - Manojlović, Milica
AU  - Filipović, Saša
PY  - 2023
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1292
AB  - Associative memory (AM) is the ability to bind new information into complex memory representations. Noninvasive brain stimulation (NIBS), especially transcranial electric stimulation (tES), has gained increased interest in research of associative memory (AM) and its impairments. To provide an overview of the current state of knowledge, we conducted a systematic review following PRISMA guidelines covering basic and clinical research. Out of 374 identified records, 41 studies were analyzed—twenty-nine in healthy young adults, six in the aging population, three comparing older and younger adults, as well as two studies on people with MCI, and one in people with Alzheimer’s dementia. Studies using transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS) as well as oscillatory (otDCS) and high-definition protocols (HD-tDCS, HD-tACS) have been included. The results showed methodological heterogeneity in terms of study design, stimulation type, and parameters, as well as outcome measures. Overall, the results show that tES is a promising method for AM enhancement, especially if the stimulation is applied over the parietal cortex and the effects are assessed in cued recall paradigms.
PB  - MDPI
T2  - Life
T1  - Transcranial Electrical Stimulation for Associative Memory Enhancement: State-of-the-Art from Basic to Clinical Research
IS  - 5
SP  - 1125
VL  - 13
DO  - 10.3390/life13051125
ER  - 

@article{
author = "Bjekić, Jovana and Manojlović, Milica and Filipović, Saša",
year = "2023",
abstract = "Associative memory (AM) is the ability to bind new information into complex memory representations. Noninvasive brain stimulation (NIBS), especially transcranial electric stimulation (tES), has gained increased interest in research of associative memory (AM) and its impairments. To provide an overview of the current state of knowledge, we conducted a systematic review following PRISMA guidelines covering basic and clinical research. Out of 374 identified records, 41 studies were analyzed—twenty-nine in healthy young adults, six in the aging population, three comparing older and younger adults, as well as two studies on people with MCI, and one in people with Alzheimer’s dementia. Studies using transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS) as well as oscillatory (otDCS) and high-definition protocols (HD-tDCS, HD-tACS) have been included. The results showed methodological heterogeneity in terms of study design, stimulation type, and parameters, as well as outcome measures. Overall, the results show that tES is a promising method for AM enhancement, especially if the stimulation is applied over the parietal cortex and the effects are assessed in cued recall paradigms.",
publisher = "MDPI",
journal = "Life",
title = "Transcranial Electrical Stimulation for Associative Memory Enhancement: State-of-the-Art from Basic to Clinical Research",
number = "5",
pages = "1125",
volume = "13",
doi = "10.3390/life13051125"
}

Bjekić, J., Manojlović, M.,& Filipović, S.. (2023). Transcranial Electrical Stimulation for Associative Memory Enhancement: State-of-the-Art from Basic to Clinical Research. in Life
MDPI., 13(5), 1125.
https://doi.org/10.3390/life13051125

Bjekić J, Manojlović M, Filipović S. Transcranial Electrical Stimulation for Associative Memory Enhancement: State-of-the-Art from Basic to Clinical Research. in Life. 2023;13(5):1125.
doi:10.3390/life13051125 .

Bjekić, Jovana, Manojlović, Milica, Filipović, Saša, "Transcranial Electrical Stimulation for Associative Memory Enhancement: State-of-the-Art from Basic to Clinical Research" in Life, 13, no. 5 (2023):1125,
https://doi.org/10.3390/life13051125 . .

TY  - JOUR
AU  - Stanković, Marija
AU  - Bjekić, Jovana
AU  - Filipović, Saša
PY  - 2023
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1298
AB  - Gambling disorder (GD) and internet gaming disorder (IGD) are formally recognized behavioral addictions with a rapidly growing prevalence and limited treatment options. Recently, transcranial electrical stimulation (tES) techniques have emerged as potentially promising interventions for improving treatment outcomes by ameliorating cognitive functions implicated in addictive behaviors. To systematize the current state of evidence and better understand whether and how tES can influence gambling and gaming-related cognitive processes, we conducted a PRISMA-guided systematic review of the literature, focusing on tES effects on gaming and gambling in a diverse range of population samples, including healthy participants, participants with GD and IGD, as well as participants with substance abuse addictions. Following the literature search in three bibliographic databases (PubMed, Web of Science, and Scopus), 40 publications were included in this review, with 26 conducted on healthy participants, 6 focusing on GD and IGD patients, and 8 including participants with other addictions. Most of the studies targeted the dorsolateral prefrontal cortex, using transcranial direct current stimulation (tDCS), and assessed the effects on cognition, using gaming and gambling computerized cognitive tasks measuring risk taking and decision making, e.g., balloon analogue risk task, Iowa gambling task, Cambridge gambling task, etc. The results indicated that tES could change gambling and gaming task performances and positively influence GD and IGD symptoms, with 70% of studies showing neuromodulatory effects. However, the results varied considerably depending on the stimulation parameters, sample characteristics, as well as outcome measures used. We discuss the sources of this variability and provide further directions for the use of tES in the context of GD and IGD treatment.
T2  - Journal of Clinical Medicine
T1  - Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder
IS  - 10
SP  - 3407
VL  - 12
DO  - 10.3390/jcm12103407
ER  - 

@article{
author = "Stanković, Marija and Bjekić, Jovana and Filipović, Saša",
year = "2023",
abstract = "Gambling disorder (GD) and internet gaming disorder (IGD) are formally recognized behavioral addictions with a rapidly growing prevalence and limited treatment options. Recently, transcranial electrical stimulation (tES) techniques have emerged as potentially promising interventions for improving treatment outcomes by ameliorating cognitive functions implicated in addictive behaviors. To systematize the current state of evidence and better understand whether and how tES can influence gambling and gaming-related cognitive processes, we conducted a PRISMA-guided systematic review of the literature, focusing on tES effects on gaming and gambling in a diverse range of population samples, including healthy participants, participants with GD and IGD, as well as participants with substance abuse addictions. Following the literature search in three bibliographic databases (PubMed, Web of Science, and Scopus), 40 publications were included in this review, with 26 conducted on healthy participants, 6 focusing on GD and IGD patients, and 8 including participants with other addictions. Most of the studies targeted the dorsolateral prefrontal cortex, using transcranial direct current stimulation (tDCS), and assessed the effects on cognition, using gaming and gambling computerized cognitive tasks measuring risk taking and decision making, e.g., balloon analogue risk task, Iowa gambling task, Cambridge gambling task, etc. The results indicated that tES could change gambling and gaming task performances and positively influence GD and IGD symptoms, with 70% of studies showing neuromodulatory effects. However, the results varied considerably depending on the stimulation parameters, sample characteristics, as well as outcome measures used. We discuss the sources of this variability and provide further directions for the use of tES in the context of GD and IGD treatment.",
journal = "Journal of Clinical Medicine",
title = "Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder",
number = "10",
pages = "3407",
volume = "12",
doi = "10.3390/jcm12103407"
}

Stanković, M., Bjekić, J.,& Filipović, S.. (2023). Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder. in Journal of Clinical Medicine, 12(10), 3407.
https://doi.org/10.3390/jcm12103407

Stanković M, Bjekić J, Filipović S. Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder. in Journal of Clinical Medicine. 2023;12(10):3407.
doi:10.3390/jcm12103407 .

Stanković, Marija, Bjekić, Jovana, Filipović, Saša, "Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder" in Journal of Clinical Medicine, 12, no. 10 (2023):3407,
https://doi.org/10.3390/jcm12103407 . .

TY  - CONF
AU  - Paunović, Dunja
AU  - Bjekić, Jovana
AU  - Filipović, Saša
PY  - 2023
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1443
AB  - Associative memory (AM) represents an ability to bind unrelated information into meaningful units and encode them as distinct memories. AM has been the function of interest in many non-invasive transcranial electrical stimulation (tES) studies aiming to maximize the potential for memory modulation by varying stimulation loci, frequency, and amplitude.
In the current study, we aimed to capture modulation potential of AM performance when tailoring the stimulation protocols to the individual brain rhythms. By matching the stimulation frequency to the frequency of each subject’s AM task-induced electrophysiological (EEG) activity in theta spectrum (4-8 Hz), we developed two types of personalized oscillatory protocols: theta-modulated transcranial direct current stimulation (otDCS) and transcranial alternating current stimulation (tACS), which we administered alongside the constant tDCS and a sham condition in the single-blind cross-over experiment. To comparatively assess the effects of different tES protocols delivered over the posterior parietal cortex, we tested the recognition and recall ability of the 42 healthy young adults on paired-associate paradigms after each of four conditions. During AM assessment participant’s EEG activity was recorded.
Group-level comparisons of each active tES condition against sham did not show differences in AM task performance either on recognition or cued-recall. However, data showed variability in performance depending on the task and the outcome measures precluding straightforward comparison between the conditions. To explore the potential sources of variability in effect expression, we propose a methodology for isolating different aspects of the function-relevant neurophysiological markers that could depict the modulatory tES effect, setting the groundwork for further analysis.
Apart from introducing a novel approach to probing AM with personalized tES, this well-powered, multi-protocol, multi-task, and multi-measure study produced a comprehensive dataset for the exploration of factors that could uncover patterns in responsiveness to tES, as well as the insight into the relationship between neurophysiological and behavioral indicators.
C3  - BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK
T1  - Theta-modulated transcranial electrical stimulation for targeting Associative memory: A cross-modal integration of EEG and behavioral indicators
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1443
ER  - 

@conference{
author = "Paunović, Dunja and Bjekić, Jovana and Filipović, Saša",
year = "2023",
abstract = "Associative memory (AM) represents an ability to bind unrelated information into meaningful units and encode them as distinct memories. AM has been the function of interest in many non-invasive transcranial electrical stimulation (tES) studies aiming to maximize the potential for memory modulation by varying stimulation loci, frequency, and amplitude.
In the current study, we aimed to capture modulation potential of AM performance when tailoring the stimulation protocols to the individual brain rhythms. By matching the stimulation frequency to the frequency of each subject’s AM task-induced electrophysiological (EEG) activity in theta spectrum (4-8 Hz), we developed two types of personalized oscillatory protocols: theta-modulated transcranial direct current stimulation (otDCS) and transcranial alternating current stimulation (tACS), which we administered alongside the constant tDCS and a sham condition in the single-blind cross-over experiment. To comparatively assess the effects of different tES protocols delivered over the posterior parietal cortex, we tested the recognition and recall ability of the 42 healthy young adults on paired-associate paradigms after each of four conditions. During AM assessment participant’s EEG activity was recorded.
Group-level comparisons of each active tES condition against sham did not show differences in AM task performance either on recognition or cued-recall. However, data showed variability in performance depending on the task and the outcome measures precluding straightforward comparison between the conditions. To explore the potential sources of variability in effect expression, we propose a methodology for isolating different aspects of the function-relevant neurophysiological markers that could depict the modulatory tES effect, setting the groundwork for further analysis.
Apart from introducing a novel approach to probing AM with personalized tES, this well-powered, multi-protocol, multi-task, and multi-measure study produced a comprehensive dataset for the exploration of factors that could uncover patterns in responsiveness to tES, as well as the insight into the relationship between neurophysiological and behavioral indicators.",
journal = "BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK",
title = "Theta-modulated transcranial electrical stimulation for targeting Associative memory: A cross-modal integration of EEG and behavioral indicators",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1443"
}

Paunović, D., Bjekić, J.,& Filipović, S.. (2023). Theta-modulated transcranial electrical stimulation for targeting Associative memory: A cross-modal integration of EEG and behavioral indicators. in BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK.
https://hdl.handle.net/21.15107/rcub_rimi_1443

Paunović D, Bjekić J, Filipović S. Theta-modulated transcranial electrical stimulation for targeting Associative memory: A cross-modal integration of EEG and behavioral indicators. in BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK. 2023;.
https://hdl.handle.net/21.15107/rcub_rimi_1443 .

Paunović, Dunja, Bjekić, Jovana, Filipović, Saša, "Theta-modulated transcranial electrical stimulation for targeting Associative memory: A cross-modal integration of EEG and behavioral indicators" in BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK (2023),
https://hdl.handle.net/21.15107/rcub_rimi_1443 .

TY  - CONF
AU  - Stanković, Marija
AU  - Bjekić, Jovana
AU  - Filipović, Saša
PY  - 2023
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1444
AB  - Gambling Disorder (GD) and Internet Gaming Disorder (IGD) are formally recognized behavioral addictions with a rapidly growing prevalence and limited treatment options. Recently, transcranial electrical stimulation (tES) techniques have emerged as potentially promising interventions for improving treatment outcomes by ameliorating cognitive functions implicated in addictive behaviors. To systematize the current state of evidence and better understand whether and how tES can influence gambling and gaming-related cognitive processes, we conducted a PRISMA-guided systematic review of the literature focusing on tES effects on risky gambling and gaming behaviors in a diverse range of population samples, including healthy participants, participants with GD and IGD, as well as substance abuse addictions. Following the literature search in three bibliographic databases (PubMed, Web of Science, and Scopus) 40 publications have been included in this review, with 26 conducted on healthy participants, six focusing on GD and IGD patients, and eight including participants with other addictions. Most of the studies targeted the dorsolateral prefrontal cortex using transcranial direct current stimulation (tDCS). The results indicated that tES could change gambling and gaming behaviors and positively influence GD and IGD symptoms. However, the results varied considerably depending on the stimulation parameters, sample characteristics, as well as outcome measures used. We discuss the sources of this variability and provide further directions for the use of tES in the context of GD and IGD treatment.
C3  - 11th IBRO World Congress of Neuroscience,09-13.September 2023, Granada, Spain
T1  - Can Transcranial Electrical Stimulation modulate gambling and gaming behaviors?
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1444
ER  - 

@conference{
author = "Stanković, Marija and Bjekić, Jovana and Filipović, Saša",
year = "2023",
abstract = "Gambling Disorder (GD) and Internet Gaming Disorder (IGD) are formally recognized behavioral addictions with a rapidly growing prevalence and limited treatment options. Recently, transcranial electrical stimulation (tES) techniques have emerged as potentially promising interventions for improving treatment outcomes by ameliorating cognitive functions implicated in addictive behaviors. To systematize the current state of evidence and better understand whether and how tES can influence gambling and gaming-related cognitive processes, we conducted a PRISMA-guided systematic review of the literature focusing on tES effects on risky gambling and gaming behaviors in a diverse range of population samples, including healthy participants, participants with GD and IGD, as well as substance abuse addictions. Following the literature search in three bibliographic databases (PubMed, Web of Science, and Scopus) 40 publications have been included in this review, with 26 conducted on healthy participants, six focusing on GD and IGD patients, and eight including participants with other addictions. Most of the studies targeted the dorsolateral prefrontal cortex using transcranial direct current stimulation (tDCS). The results indicated that tES could change gambling and gaming behaviors and positively influence GD and IGD symptoms. However, the results varied considerably depending on the stimulation parameters, sample characteristics, as well as outcome measures used. We discuss the sources of this variability and provide further directions for the use of tES in the context of GD and IGD treatment.",
journal = "11th IBRO World Congress of Neuroscience,09-13.September 2023, Granada, Spain",
title = "Can Transcranial Electrical Stimulation modulate gambling and gaming behaviors?",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1444"
}

Stanković, M., Bjekić, J.,& Filipović, S.. (2023). Can Transcranial Electrical Stimulation modulate gambling and gaming behaviors?. in 11th IBRO World Congress of Neuroscience,09-13.September 2023, Granada, Spain.
https://hdl.handle.net/21.15107/rcub_rimi_1444

Stanković M, Bjekić J, Filipović S. Can Transcranial Electrical Stimulation modulate gambling and gaming behaviors?. in 11th IBRO World Congress of Neuroscience,09-13.September 2023, Granada, Spain. 2023;.
https://hdl.handle.net/21.15107/rcub_rimi_1444 .

Stanković, Marija, Bjekić, Jovana, Filipović, Saša, "Can Transcranial Electrical Stimulation modulate gambling and gaming behaviors?" in 11th IBRO World Congress of Neuroscience,09-13.September 2023, Granada, Spain (2023),
https://hdl.handle.net/21.15107/rcub_rimi_1444 .

TY  - CONF
AU  - Stanković, Marija
AU  - Bjekić, Jovana
AU  - Teovanović, P.
AU  - Konstantinović, Uroš
AU  - Paunović, Dunja
AU  - Đukić, Bojana
AU  - Filipović, Saša
PY  - 2023
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1445
AB  - Gambling represents a reward-based activity that many people engage in for fun and leisure. However, excessive gambling may lead to Gambling Disorder (GD), the most prevalent behavioural addiction. There is evidence that neural circuits behind some of the cognitive processes that drive GD can be modulated by Transcranial Electrical Stimulation (tES). To comprehensively understand the potential of tES in targeting cognitive mechanisms implicated in GD, we conducted a PRISMA-guided systematic review of studies that applied tES to modulate gambling-related cognitive processes in a diverse range of population samples, including healthy participants, participants with GD, as well as other addictions. Most of the studies used transcranial direct current stimulation (tDCS) to target dorsolateral prefrontal cortex (DLPFC). While 70% of studies showed neuromodulatory effects, the results varied considerably depending on the stimulation parameters, sample characteristics, as well as outcome measures used. We noticed that studies predominantly focused on the DLPFC without providing a clear rationale, even though other brain regions have shown greater relevance to the cognitive functions affected in GD. Furthermore, we have identified a gap in the existing literature regarding the use of tES among participants with gambling-related issues. Based on these findings, we propose a study protocol for investigating the effects of tES on cognitive functions affected in GD, in a sample of at-risk gamblers. In a sham-controlled, parallel-group study we will use multichannel tDCS to modulate the activity of anterior cingulate cortex, due to its key role in gambling-related cognitive processes. The electrode montage will be optimized based on current flow modeling. We will test the effects on cognitive tasks measuring risk-taking, impulsivity, inhibition, and decision-making. In addition to at risk-gamblers, we will sample control participants with no gambling-related issues. This approach will enable us to examine whether and how this factor may determine the responsiveness to tES.
C3  - BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK, 2023
T1  - Using Transcranial Electrical Stimulation to modulate gambling-related cognitive functions: A systematic review and study protocol
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1445
ER  - 

@conference{
author = "Stanković, Marija and Bjekić, Jovana and Teovanović, P. and Konstantinović, Uroš and Paunović, Dunja and Đukić, Bojana and Filipović, Saša",
year = "2023",
abstract = "Gambling represents a reward-based activity that many people engage in for fun and leisure. However, excessive gambling may lead to Gambling Disorder (GD), the most prevalent behavioural addiction. There is evidence that neural circuits behind some of the cognitive processes that drive GD can be modulated by Transcranial Electrical Stimulation (tES). To comprehensively understand the potential of tES in targeting cognitive mechanisms implicated in GD, we conducted a PRISMA-guided systematic review of studies that applied tES to modulate gambling-related cognitive processes in a diverse range of population samples, including healthy participants, participants with GD, as well as other addictions. Most of the studies used transcranial direct current stimulation (tDCS) to target dorsolateral prefrontal cortex (DLPFC). While 70% of studies showed neuromodulatory effects, the results varied considerably depending on the stimulation parameters, sample characteristics, as well as outcome measures used. We noticed that studies predominantly focused on the DLPFC without providing a clear rationale, even though other brain regions have shown greater relevance to the cognitive functions affected in GD. Furthermore, we have identified a gap in the existing literature regarding the use of tES among participants with gambling-related issues. Based on these findings, we propose a study protocol for investigating the effects of tES on cognitive functions affected in GD, in a sample of at-risk gamblers. In a sham-controlled, parallel-group study we will use multichannel tDCS to modulate the activity of anterior cingulate cortex, due to its key role in gambling-related cognitive processes. The electrode montage will be optimized based on current flow modeling. We will test the effects on cognitive tasks measuring risk-taking, impulsivity, inhibition, and decision-making. In addition to at risk-gamblers, we will sample control participants with no gambling-related issues. This approach will enable us to examine whether and how this factor may determine the responsiveness to tES.",
journal = "BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK, 2023",
title = "Using Transcranial Electrical Stimulation to modulate gambling-related cognitive functions: A systematic review and study protocol",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1445"
}

Stanković, M., Bjekić, J., Teovanović, P., Konstantinović, U., Paunović, D., Đukić, B.,& Filipović, S.. (2023). Using Transcranial Electrical Stimulation to modulate gambling-related cognitive functions: A systematic review and study protocol. in BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK, 2023.
https://hdl.handle.net/21.15107/rcub_rimi_1445

Stanković M, Bjekić J, Teovanović P, Konstantinović U, Paunović D, Đukić B, Filipović S. Using Transcranial Electrical Stimulation to modulate gambling-related cognitive functions: A systematic review and study protocol. in BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK, 2023. 2023;.
https://hdl.handle.net/21.15107/rcub_rimi_1445 .

Stanković, Marija, Bjekić, Jovana, Teovanović, P., Konstantinović, Uroš, Paunović, Dunja, Đukić, Bojana, Filipović, Saša, "Using Transcranial Electrical Stimulation to modulate gambling-related cognitive functions: A systematic review and study protocol" in BrainBox Initiative Conference 2023, 21-23 September 2023, London, UK, 2023 (2023),
https://hdl.handle.net/21.15107/rcub_rimi_1445 .

TY  - JOUR
AU  - Stanković, Marija
AU  - Živanović, Marko
AU  - Bjekić, Jovana
AU  - Filipović, Saša
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1186
AB  - Transcranial direct current stimulation (tDCS) has become a valuable tool in cognitive neuroscience research as it enables causal inferences about neural underpinnings of cognition. However, studies using tDCS to modulate cognitive functions often yield inconsistent findings. Hence, there is an increasing interest in factors that may moderate the effects, one of which is the participants’ beliefs of the tDCS condition (i.e., real or sham) they received. Namely, whether participants’ correct guessing of sham condition may lead to false-positive tDCS effects. In this study, we aimed to explore if participants’ beliefs about received stimulation type (i.e., the success of blinding) impacted their task performance in tDCS experiments on associative (AM) and working memory (WM). We analyzed data from four within-subject, sham-controlled tDCS memory experiments (N = 83) to check if the correct end-of-study guess of sham condition moderated tDCS effects. We found no evidence that sham guessing moderated post-tDCS memory performance in experiments in which tDCS effects were observed as well as in experiments that showed null effects of tDCS. The results suggest that the correct sham guessing (i.e., placebo-like effect) is unlikely to influence the results in tDCS memory experiments. We discuss the results in light of the growing debate about the relevance and effectiveness of blinding in brain stimulation research.
PB  - MDPI
T2  - Brain Sciences
T1  - Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory
IS  - 1
SP  - 58
VL  - 12
DO  - 10.3390/brainsci12010058
ER  - 

@article{
author = "Stanković, Marija and Živanović, Marko and Bjekić, Jovana and Filipović, Saša",
year = "2022",
abstract = "Transcranial direct current stimulation (tDCS) has become a valuable tool in cognitive neuroscience research as it enables causal inferences about neural underpinnings of cognition. However, studies using tDCS to modulate cognitive functions often yield inconsistent findings. Hence, there is an increasing interest in factors that may moderate the effects, one of which is the participants’ beliefs of the tDCS condition (i.e., real or sham) they received. Namely, whether participants’ correct guessing of sham condition may lead to false-positive tDCS effects. In this study, we aimed to explore if participants’ beliefs about received stimulation type (i.e., the success of blinding) impacted their task performance in tDCS experiments on associative (AM) and working memory (WM). We analyzed data from four within-subject, sham-controlled tDCS memory experiments (N = 83) to check if the correct end-of-study guess of sham condition moderated tDCS effects. We found no evidence that sham guessing moderated post-tDCS memory performance in experiments in which tDCS effects were observed as well as in experiments that showed null effects of tDCS. The results suggest that the correct sham guessing (i.e., placebo-like effect) is unlikely to influence the results in tDCS memory experiments. We discuss the results in light of the growing debate about the relevance and effectiveness of blinding in brain stimulation research.",
publisher = "MDPI",
journal = "Brain Sciences",
title = "Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory",
number = "1",
pages = "58",
volume = "12",
doi = "10.3390/brainsci12010058"
}

Stanković, M., Živanović, M., Bjekić, J.,& Filipović, S.. (2022). Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory. in Brain Sciences
MDPI., 12(1), 58.
https://doi.org/10.3390/brainsci12010058

Stanković M, Živanović M, Bjekić J, Filipović S. Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory. in Brain Sciences. 2022;12(1):58.
doi:10.3390/brainsci12010058 .

Stanković, Marija, Živanović, Marko, Bjekić, Jovana, Filipović, Saša, "Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory" in Brain Sciences, 12, no. 1 (2022):58,
https://doi.org/10.3390/brainsci12010058 . .

TY  - JOUR
AU  - Vasić, Ana
AU  - Bjekić, Jovana
AU  - Veinović, Gorana
AU  - Mihaljica, Darko
AU  - Sukara, Ratko
AU  - Poluga, Jasmina
AU  - Filipović, Saša
AU  - Tomanović, Snežana
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1213
AB  - This study assessed the level of knowledge, attitudes, and practices (KAP) regarding tick-borne encephalitis virus (TBEV) and tick-borne diseases (TBDs) among different groups of people in Serbia. Professionally tick-exposed persons (PTEPs), health care workers (HCWs), and the general population (GP) were subjected to an anonymous, voluntary, online questionnaire using Microsoft Forms. A total of 663 questionnaire responses were collected (February–March 2021), while 642 were included in the analysis. The significant difference in knowledge in TBDs existed between GP and PTEPs, and HCWs (p < 0.001). The perception of risk-to-tick exposure and TBDs was generally high (42.4 (95% CI: 33.6–51.2) within GP, 44.9 (95% CI: 35.8–53.9) within PTEPs and 46.2 (95% CI: 38.0–54.5) within HCWs), while fear was low (13.7 (95% CI: 7.9–19.5) within GP, 12.6 (95% CI: 7.3–19.9) within PTEPs, and 13.5 (95% CI: 7.4–19.5) within HCWs). Protective practices differed across groups (F (2639) = 12.920, p < 0.001, η2 = 0.039), with both PTEPs (t = 3.621, Cohen d = 0.332, p < 0.001) and HCWs (t = 4.644, Cohen d = 0.468, p < 0.001) adhering to more protective practices than the GP, without differences between PTEPs and HCWs (t = 1.256, Cohen d = 0.137, p = 0.421). Further education about TBDs in Serbia is required and critical points were identified in this study.
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
T2  - International Journal of Environmental Research and Public Health
T1  - Knowledge, Attitudes, and Practices on Tick-Borne Encephalitis Virus and Tick-Borne Diseases within Professionally Tick-Exposed Persons, Health Care Workers, and General Population in Serbia: A Questionnaire-Based Study
IS  - 2
SP  - 867
VL  - 19
DO  - 10.3390/ijerph19020867
ER  - 

@article{
author = "Vasić, Ana and Bjekić, Jovana and Veinović, Gorana and Mihaljica, Darko and Sukara, Ratko and Poluga, Jasmina and Filipović, Saša and Tomanović, Snežana",
year = "2022",
abstract = "This study assessed the level of knowledge, attitudes, and practices (KAP) regarding tick-borne encephalitis virus (TBEV) and tick-borne diseases (TBDs) among different groups of people in Serbia. Professionally tick-exposed persons (PTEPs), health care workers (HCWs), and the general population (GP) were subjected to an anonymous, voluntary, online questionnaire using Microsoft Forms. A total of 663 questionnaire responses were collected (February–March 2021), while 642 were included in the analysis. The significant difference in knowledge in TBDs existed between GP and PTEPs, and HCWs (p < 0.001). The perception of risk-to-tick exposure and TBDs was generally high (42.4 (95% CI: 33.6–51.2) within GP, 44.9 (95% CI: 35.8–53.9) within PTEPs and 46.2 (95% CI: 38.0–54.5) within HCWs), while fear was low (13.7 (95% CI: 7.9–19.5) within GP, 12.6 (95% CI: 7.3–19.9) within PTEPs, and 13.5 (95% CI: 7.4–19.5) within HCWs). Protective practices differed across groups (F (2639) = 12.920, p < 0.001, η2 = 0.039), with both PTEPs (t = 3.621, Cohen d = 0.332, p < 0.001) and HCWs (t = 4.644, Cohen d = 0.468, p < 0.001) adhering to more protective practices than the GP, without differences between PTEPs and HCWs (t = 1.256, Cohen d = 0.137, p = 0.421). Further education about TBDs in Serbia is required and critical points were identified in this study.",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "International Journal of Environmental Research and Public Health",
title = "Knowledge, Attitudes, and Practices on Tick-Borne Encephalitis Virus and Tick-Borne Diseases within Professionally Tick-Exposed Persons, Health Care Workers, and General Population in Serbia: A Questionnaire-Based Study",
number = "2",
pages = "867",
volume = "19",
doi = "10.3390/ijerph19020867"
}

Vasić, A., Bjekić, J., Veinović, G., Mihaljica, D., Sukara, R., Poluga, J., Filipović, S.,& Tomanović, S.. (2022). Knowledge, Attitudes, and Practices on Tick-Borne Encephalitis Virus and Tick-Borne Diseases within Professionally Tick-Exposed Persons, Health Care Workers, and General Population in Serbia: A Questionnaire-Based Study. in International Journal of Environmental Research and Public Health
Multidisciplinary Digital Publishing Institute (MDPI)., 19(2), 867.
https://doi.org/10.3390/ijerph19020867

Vasić A, Bjekić J, Veinović G, Mihaljica D, Sukara R, Poluga J, Filipović S, Tomanović S. Knowledge, Attitudes, and Practices on Tick-Borne Encephalitis Virus and Tick-Borne Diseases within Professionally Tick-Exposed Persons, Health Care Workers, and General Population in Serbia: A Questionnaire-Based Study. in International Journal of Environmental Research and Public Health. 2022;19(2):867.
doi:10.3390/ijerph19020867 .

Vasić, Ana, Bjekić, Jovana, Veinović, Gorana, Mihaljica, Darko, Sukara, Ratko, Poluga, Jasmina, Filipović, Saša, Tomanović, Snežana, "Knowledge, Attitudes, and Practices on Tick-Borne Encephalitis Virus and Tick-Borne Diseases within Professionally Tick-Exposed Persons, Health Care Workers, and General Population in Serbia: A Questionnaire-Based Study" in International Journal of Environmental Research and Public Health, 19, no. 2 (2022):867,
https://doi.org/10.3390/ijerph19020867 . .

TY  - JOUR
AU  - Bjekić, Jovana
AU  - Živanović, Marko
AU  - Paunović, Dunja
AU  - Vulić, Katarina
AU  - Konstantinović, Uroš
AU  - Filipović, Saša
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1230
AB  - Associative memory (AM) is the ability to remember the relationship between previously unrelated items. AM is significantly affected by normal aging and neurodegenerative conditions, thus there is a growing interest in applying non-invasive brain stimulation (NIBS) techniques for AM enhancement. A growing body of studies identifies posterior parietal cortex (PPC) as the most promising cortical target for both transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to modulate a cortico-hippocampal network that underlines AM. In that sense, theta frequency oscillatory tES protocols, targeted towards the hallmark oscillatory activity within the cortico-hippocampal network, are increasingly coming to prominence. To increase precision and effectiveness, the need for EEG guided individualization of the tES protocols is proposed. Here, we present the study protocol in which two types of personalized oscillatory tES–transcranial alternating current stimulation (tACS) and oscillatory transcranial direct current stimulation (otDCS), both frequency-modulated to the individual theta-band frequency (ITF), are compared to the non-oscillatory transcranial direct current stimulation (tDCS) and to the sham stimulation. The study has cross-over design with four tES conditions (tACS, otDCS, tDCS, sham), and the comprehensive set of neurophysiological (resting state EEG and AM-evoked EEG) and behavioral outcomes, including AM tasks (short-term associative memory, face–word, face–object, object-location), as well as measures of other cognitive functions (cognitive control, verbal fluency, and working memory).
T2  - Brain Sciences
T1  - Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement
IS  - 4
SP  - 472
VL  - 12
DO  - 10.3390/brainsci12040472
ER  - 

@article{
author = "Bjekić, Jovana and Živanović, Marko and Paunović, Dunja and Vulić, Katarina and Konstantinović, Uroš and Filipović, Saša",
year = "2022",
abstract = "Associative memory (AM) is the ability to remember the relationship between previously unrelated items. AM is significantly affected by normal aging and neurodegenerative conditions, thus there is a growing interest in applying non-invasive brain stimulation (NIBS) techniques for AM enhancement. A growing body of studies identifies posterior parietal cortex (PPC) as the most promising cortical target for both transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to modulate a cortico-hippocampal network that underlines AM. In that sense, theta frequency oscillatory tES protocols, targeted towards the hallmark oscillatory activity within the cortico-hippocampal network, are increasingly coming to prominence. To increase precision and effectiveness, the need for EEG guided individualization of the tES protocols is proposed. Here, we present the study protocol in which two types of personalized oscillatory tES–transcranial alternating current stimulation (tACS) and oscillatory transcranial direct current stimulation (otDCS), both frequency-modulated to the individual theta-band frequency (ITF), are compared to the non-oscillatory transcranial direct current stimulation (tDCS) and to the sham stimulation. The study has cross-over design with four tES conditions (tACS, otDCS, tDCS, sham), and the comprehensive set of neurophysiological (resting state EEG and AM-evoked EEG) and behavioral outcomes, including AM tasks (short-term associative memory, face–word, face–object, object-location), as well as measures of other cognitive functions (cognitive control, verbal fluency, and working memory).",
journal = "Brain Sciences",
title = "Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement",
number = "4",
pages = "472",
volume = "12",
doi = "10.3390/brainsci12040472"
}

Bjekić, J., Živanović, M., Paunović, D., Vulić, K., Konstantinović, U.,& Filipović, S.. (2022). Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement. in Brain Sciences, 12(4), 472.
https://doi.org/10.3390/brainsci12040472

Bjekić J, Živanović M, Paunović D, Vulić K, Konstantinović U, Filipović S. Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement. in Brain Sciences. 2022;12(4):472.
doi:10.3390/brainsci12040472 .

Bjekić, Jovana, Živanović, Marko, Paunović, Dunja, Vulić, Katarina, Konstantinović, Uroš, Filipović, Saša, "Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement" in Brain Sciences, 12, no. 4 (2022):472,
https://doi.org/10.3390/brainsci12040472 . .

TY  - JOUR
AU  - Živanović, Marko
AU  - Bjekić, Jovana
AU  - Konstantinović, Uroš
AU  - Filipović, Saša
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1254
AB  - Associative memory (AM) is the ability to remember and retrieve multiple items bound together. Previous studies aiming to modulate AM by various transcranial electric stimulation (tES) techniques were inconclusive, although overall suggestive that tES could be a tool for AM enhancement. However, evidence from a direct comparison between different tES techniques is lacking. Here, in a sham-controlled cross-over experiment, we comparatively assessed the effects of three types of tES—anodal tDCS, theta-band transcranial alternating current stimulation (tACS), and theta-oscillatory tDCS (otDCS), delivered over the left posterior parietal cortex, during a short-term digit-color AM task with cued-recall. The effects were tested in 40 healthy young participants while both oscillatory tES were delivered at a previously determined individual theta frequency (4–8 Hz). All three active stimulations facilitated the overall AM performance, and no differences could be detected between them on direct comparison. However, unlike tDCS, the effects of which appeared to stem mainly from the facilitation of low-memory demand trials, both theta-modulated tACS and otDCS primarily promoted AM in high memory demand trials. Comparable yet differential effects of tDCS, theta tACS, and otDCS could be attributed to differences in their presumed modes of action.
PB  - Springer Nature
T2  - Scientific Reports
T1  - Effects of online parietal transcranial electric stimulation on associative memory: a direct comparison between tDCS, theta tACS, and theta-oscillatory tDCS
IS  - 1
SP  - 14091
VL  - 12
DO  - 10.1038/s41598-022-18376-5
ER  - 

@article{
author = "Živanović, Marko and Bjekić, Jovana and Konstantinović, Uroš and Filipović, Saša",
year = "2022",
abstract = "Associative memory (AM) is the ability to remember and retrieve multiple items bound together. Previous studies aiming to modulate AM by various transcranial electric stimulation (tES) techniques were inconclusive, although overall suggestive that tES could be a tool for AM enhancement. However, evidence from a direct comparison between different tES techniques is lacking. Here, in a sham-controlled cross-over experiment, we comparatively assessed the effects of three types of tES—anodal tDCS, theta-band transcranial alternating current stimulation (tACS), and theta-oscillatory tDCS (otDCS), delivered over the left posterior parietal cortex, during a short-term digit-color AM task with cued-recall. The effects were tested in 40 healthy young participants while both oscillatory tES were delivered at a previously determined individual theta frequency (4–8 Hz). All three active stimulations facilitated the overall AM performance, and no differences could be detected between them on direct comparison. However, unlike tDCS, the effects of which appeared to stem mainly from the facilitation of low-memory demand trials, both theta-modulated tACS and otDCS primarily promoted AM in high memory demand trials. Comparable yet differential effects of tDCS, theta tACS, and otDCS could be attributed to differences in their presumed modes of action.",
publisher = "Springer Nature",
journal = "Scientific Reports",
title = "Effects of online parietal transcranial electric stimulation on associative memory: a direct comparison between tDCS, theta tACS, and theta-oscillatory tDCS",
number = "1",
pages = "14091",
volume = "12",
doi = "10.1038/s41598-022-18376-5"
}

Živanović, M., Bjekić, J., Konstantinović, U.,& Filipović, S.. (2022). Effects of online parietal transcranial electric stimulation on associative memory: a direct comparison between tDCS, theta tACS, and theta-oscillatory tDCS. in Scientific Reports
Springer Nature., 12(1), 14091.
https://doi.org/10.1038/s41598-022-18376-5

Živanović M, Bjekić J, Konstantinović U, Filipović S. Effects of online parietal transcranial electric stimulation on associative memory: a direct comparison between tDCS, theta tACS, and theta-oscillatory tDCS. in Scientific Reports. 2022;12(1):14091.
doi:10.1038/s41598-022-18376-5 .

Živanović, Marko, Bjekić, Jovana, Konstantinović, Uroš, Filipović, Saša, "Effects of online parietal transcranial electric stimulation on associative memory: a direct comparison between tDCS, theta tACS, and theta-oscillatory tDCS" in Scientific Reports, 12, no. 1 (2022):14091,
https://doi.org/10.1038/s41598-022-18376-5 . .

TY  - JOUR
AU  - Bjekić, Jovana
AU  - Paunović, Dunja
AU  - Živanović, Marko
AU  - Stanković, Marija
AU  - Griskova-Bulanova, Inga
AU  - Filipović, Saša
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1259
AB  - Non-invasive brain stimulation (NIBS) methods have gained increased interest in research and therapy of associative memory (AM) and its impairments. However, the one-size-fits-all approach yields inconsistent findings, thus putting forward the need for electroencephalography (EEG)-guided personalized frequency-modulated NIBS protocols to increase the focality and the effectiveness of the interventions. Still, extraction of individual frequency, especially in the theta band, turned out to be a challenging task. Here we present an approach to extracting the individual theta-band frequency (ITF) from EEG signals recorded during the AM task. The method showed a 93% success rate, good reliability, and the full range of variability of the extracted ITFs. This paper provides a rationale behind the adopted approach and critically evaluates it in comparison to the alternative methods that have been reported in the literature. Finally, we discuss how it could be used as an input parameter for personalized frequency-modulated NIBS approaches—transcranial alternating current stimulation (tACS) and transcranial oscillatory current stimulation (otDCS) directed at AM neuromodulation.
PB  - Frontiers Media S.A.
T2  - Journal of Personalized Medicine
T1  - Determining the Individual Theta Frequency for Associative Memory Targeted Personalized Transcranial Brain Stimulation
IS  - 9
SP  - 1367
VL  - 12
DO  - 10.3390/jpm12091367
ER  - 

@article{
author = "Bjekić, Jovana and Paunović, Dunja and Živanović, Marko and Stanković, Marija and Griskova-Bulanova, Inga and Filipović, Saša",
year = "2022",
abstract = "Non-invasive brain stimulation (NIBS) methods have gained increased interest in research and therapy of associative memory (AM) and its impairments. However, the one-size-fits-all approach yields inconsistent findings, thus putting forward the need for electroencephalography (EEG)-guided personalized frequency-modulated NIBS protocols to increase the focality and the effectiveness of the interventions. Still, extraction of individual frequency, especially in the theta band, turned out to be a challenging task. Here we present an approach to extracting the individual theta-band frequency (ITF) from EEG signals recorded during the AM task. The method showed a 93% success rate, good reliability, and the full range of variability of the extracted ITFs. This paper provides a rationale behind the adopted approach and critically evaluates it in comparison to the alternative methods that have been reported in the literature. Finally, we discuss how it could be used as an input parameter for personalized frequency-modulated NIBS approaches—transcranial alternating current stimulation (tACS) and transcranial oscillatory current stimulation (otDCS) directed at AM neuromodulation.",
publisher = "Frontiers Media S.A.",
journal = "Journal of Personalized Medicine",
title = "Determining the Individual Theta Frequency for Associative Memory Targeted Personalized Transcranial Brain Stimulation",
number = "9",
pages = "1367",
volume = "12",
doi = "10.3390/jpm12091367"
}

Bjekić, J., Paunović, D., Živanović, M., Stanković, M., Griskova-Bulanova, I.,& Filipović, S.. (2022). Determining the Individual Theta Frequency for Associative Memory Targeted Personalized Transcranial Brain Stimulation. in Journal of Personalized Medicine
Frontiers Media S.A.., 12(9), 1367.
https://doi.org/10.3390/jpm12091367

Bjekić J, Paunović D, Živanović M, Stanković M, Griskova-Bulanova I, Filipović S. Determining the Individual Theta Frequency for Associative Memory Targeted Personalized Transcranial Brain Stimulation. in Journal of Personalized Medicine. 2022;12(9):1367.
doi:10.3390/jpm12091367 .

Bjekić, Jovana, Paunović, Dunja, Živanović, Marko, Stanković, Marija, Griskova-Bulanova, Inga, Filipović, Saša, "Determining the Individual Theta Frequency for Associative Memory Targeted Personalized Transcranial Brain Stimulation" in Journal of Personalized Medicine, 12, no. 9 (2022):1367,
https://doi.org/10.3390/jpm12091367 . .

TY  - GEN
AU  - Bjekić, Jovana
AU  - Paunović, Dunja
AU  - Živanović, Marko
AU  - Stanković, Marija
AU  - Griškova-Bulanova, Inga
AU  - Filipović, Saša
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1356
AB  - Non-invasive brain stimulation (NIBS) has gained increased interest in research and therapy of associative memory (AM) and its impairments. However, the one-size-fits-all approach yields inconsistent findings, thus putting forward the need for the development of personalized frequency-modulated NIBS protocols to increase the focality and the effectiveness of the interventions. There have been only a few attempts to deliver theta frequency-personalized tES. The current study explores the feasibility of determining dominant individual theta-band frequency (ITF) based on AM task evoked EEG activity. In a sample of 42 healthy young adults, we extracted the frequencies (2-15 Hz, in 0.5 Hz steps) with the highest event-related spectral perturbation from the EEG recorded during successful encoding in the AM task. The developed method for extraction of the dominant theta-band frequency based on the AM-evoked EEG changes is able to reliably determine the AM-related ITF and can be used for personalization of the oscillatory NIBS techniques.
PB  - Cold Spring Harbor Laboratory
T2  - bioRxiv
T1  - Extraction of individual associative memory related dominant theta frequency for personalized transcranial brain stimulation
DO  - 10.1101/2022.03.07.483124
ER  - 

@misc{
author = "Bjekić, Jovana and Paunović, Dunja and Živanović, Marko and Stanković, Marija and Griškova-Bulanova, Inga and Filipović, Saša",
year = "2022",
abstract = "Non-invasive brain stimulation (NIBS) has gained increased interest in research and therapy of associative memory (AM) and its impairments. However, the one-size-fits-all approach yields inconsistent findings, thus putting forward the need for the development of personalized frequency-modulated NIBS protocols to increase the focality and the effectiveness of the interventions. There have been only a few attempts to deliver theta frequency-personalized tES. The current study explores the feasibility of determining dominant individual theta-band frequency (ITF) based on AM task evoked EEG activity. In a sample of 42 healthy young adults, we extracted the frequencies (2-15 Hz, in 0.5 Hz steps) with the highest event-related spectral perturbation from the EEG recorded during successful encoding in the AM task. The developed method for extraction of the dominant theta-band frequency based on the AM-evoked EEG changes is able to reliably determine the AM-related ITF and can be used for personalization of the oscillatory NIBS techniques.",
publisher = "Cold Spring Harbor Laboratory",
journal = "bioRxiv",
title = "Extraction of individual associative memory related dominant theta frequency for personalized transcranial brain stimulation",
doi = "10.1101/2022.03.07.483124"
}

Bjekić, J., Paunović, D., Živanović, M., Stanković, M., Griškova-Bulanova, I.,& Filipović, S.. (2022). Extraction of individual associative memory related dominant theta frequency for personalized transcranial brain stimulation. in bioRxiv
Cold Spring Harbor Laboratory..
https://doi.org/10.1101/2022.03.07.483124

Bjekić J, Paunović D, Živanović M, Stanković M, Griškova-Bulanova I, Filipović S. Extraction of individual associative memory related dominant theta frequency for personalized transcranial brain stimulation. in bioRxiv. 2022;.
doi:10.1101/2022.03.07.483124 .

Bjekić, Jovana, Paunović, Dunja, Živanović, Marko, Stanković, Marija, Griškova-Bulanova, Inga, Filipović, Saša, "Extraction of individual associative memory related dominant theta frequency for personalized transcranial brain stimulation" in bioRxiv (2022),
https://doi.org/10.1101/2022.03.07.483124 . .

TY  - CONF
AU  - Vulić, Katarina
AU  - Bajada, Claude
AU  - Paunović, Dunja
AU  - Bjekić, Jovana
AU  - Filipović, Saša
AU  - Sandberg, Kristian
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1358
AB  - The hippocampus (HC) is traditionally considered the key neuroanatomical hub responsible for memory. However, previous MRI studies that aimed to relate volumetric hippocampal measures to associative memory (AM) performance have yielded mixed results. In the current study, we aimed to reevaluate these findings in a large sample of young healthy participants (N = 246; age M = 24.95, SD = 4.58; 56% female). Participants were scanned with 3T MAGNETOM Prisma using a 64-channel head coil, followed by the AM assessment in the lab setting. To maximize the scope of AM assessment, we employed four paired-associate tasks of various stimuli modalities (faces, words, scenes) and outcome measure types (recognition, recall). Synthetic T1-weighted images were produced out of relaxometry parameter maps, after which volumetric measures were 
calculated using FreeSurfer. The whole HC volume showed no correlation with any of the memory measures. However, further segmentation of HC into its functional and anatomical subfields (Parasubiculum, Presubiculum, Subiculum, CA1, CA2/3, CA4, GC-DG, HATA, Fimbria, Molecular layer, Hippocampal fissure, Hippocampal tail) showed scattered yet consistent patterns of significant correlations between different subfield volumes and memory outcomes. The results suggest that distinctive contributions of HC subfields may lead to a null effect when the whole HC volume is considered, thus demonstrating that drawing conclusions based on the volumetric measures of neural macrostructures can be misleading. The results highlight the importance of in-depth segmentation for neural mapping.
C3  - FENS Forum 2022, E-Book of Abstracts, 09-13th July, Paris, France
T1  - On the importance of hippocampal segmentation for the neural mapping of memory: Evidence from a large-scale study of neural architecture in healthy adults
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1358
ER  - 

@conference{
author = "Vulić, Katarina and Bajada, Claude and Paunović, Dunja and Bjekić, Jovana and Filipović, Saša and Sandberg, Kristian",
year = "2022",
abstract = "The hippocampus (HC) is traditionally considered the key neuroanatomical hub responsible for memory. However, previous MRI studies that aimed to relate volumetric hippocampal measures to associative memory (AM) performance have yielded mixed results. In the current study, we aimed to reevaluate these findings in a large sample of young healthy participants (N = 246; age M = 24.95, SD = 4.58; 56% female). Participants were scanned with 3T MAGNETOM Prisma using a 64-channel head coil, followed by the AM assessment in the lab setting. To maximize the scope of AM assessment, we employed four paired-associate tasks of various stimuli modalities (faces, words, scenes) and outcome measure types (recognition, recall). Synthetic T1-weighted images were produced out of relaxometry parameter maps, after which volumetric measures were 
calculated using FreeSurfer. The whole HC volume showed no correlation with any of the memory measures. However, further segmentation of HC into its functional and anatomical subfields (Parasubiculum, Presubiculum, Subiculum, CA1, CA2/3, CA4, GC-DG, HATA, Fimbria, Molecular layer, Hippocampal fissure, Hippocampal tail) showed scattered yet consistent patterns of significant correlations between different subfield volumes and memory outcomes. The results suggest that distinctive contributions of HC subfields may lead to a null effect when the whole HC volume is considered, thus demonstrating that drawing conclusions based on the volumetric measures of neural macrostructures can be misleading. The results highlight the importance of in-depth segmentation for neural mapping.",
journal = "FENS Forum 2022, E-Book of Abstracts, 09-13th July, Paris, France",
title = "On the importance of hippocampal segmentation for the neural mapping of memory: Evidence from a large-scale study of neural architecture in healthy adults",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1358"
}

Vulić, K., Bajada, C., Paunović, D., Bjekić, J., Filipović, S.,& Sandberg, K.. (2022). On the importance of hippocampal segmentation for the neural mapping of memory: Evidence from a large-scale study of neural architecture in healthy adults. in FENS Forum 2022, E-Book of Abstracts, 09-13th July, Paris, France.
https://hdl.handle.net/21.15107/rcub_rimi_1358

Vulić K, Bajada C, Paunović D, Bjekić J, Filipović S, Sandberg K. On the importance of hippocampal segmentation for the neural mapping of memory: Evidence from a large-scale study of neural architecture in healthy adults. in FENS Forum 2022, E-Book of Abstracts, 09-13th July, Paris, France. 2022;.
https://hdl.handle.net/21.15107/rcub_rimi_1358 .

Vulić, Katarina, Bajada, Claude, Paunović, Dunja, Bjekić, Jovana, Filipović, Saša, Sandberg, Kristian, "On the importance of hippocampal segmentation for the neural mapping of memory: Evidence from a large-scale study of neural architecture in healthy adults" in FENS Forum 2022, E-Book of Abstracts, 09-13th July, Paris, France (2022),
https://hdl.handle.net/21.15107/rcub_rimi_1358 .

TY  - JOUR
AU  - Vulić, Katarina
AU  - Bjekić, Jovana
AU  - Paunović, Dunja
AU  - Jovanović, Miloš
AU  - Milanović, Slađan
AU  - Filipović, Saša
PY  - 2021
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1087
AB  - Associative memory (AM) reflects the ability to remember and retrieve multiple pieces of information bound together thus enabling complex episodic experiences. Despite growing interest in the use of transcranial direct current stimulation (tDCS) for the modulation of AM, there are inconsistent evidence regarding its benefits. An alternative to standard constant tDCS could be the application of frequency-modulated tDCS protocols, that mimic natural function-relevant brain rhythms. Here, we show the effects of anodal tDCS oscillating in theta rhythm (5 Hz; 1.5 ± 0.1 mA) versus constant anodal tDCS and sham over left posterior parietal cortex on cued recall of face-word associations. In a crossover design, each participant completed AM assessment immediately following 20-min theta-oscillatory, constant, and sham tDCS, as well as 1 and 5 days after. Theta oscillatory tDCS increased initial AM performance in comparison to sham, and so did constant tDCS. On the group level, no differences between oscillatory and constant tDCS were observed, but individual-level analysis revealed that some participants responded to theta-oscillatory but not to constant tDCS, and vice versa, which could be attributed to their different physiological modes of action. This study shows the potential of oscillatory tDCS protocols for memory enhancement to produce strong and reliable memory-modulating effects which deserve to be investigated further.
T2  - Scientific Reports
T1  - Theta-modulated oscillatory transcranial direct current stimulation over posterior parietal cortex improves associative memory
IS  - 1
SP  - 3013
VL  - 11
DO  - 10.1038/s41598-021-82577-7
ER  - 

@article{
author = "Vulić, Katarina and Bjekić, Jovana and Paunović, Dunja and Jovanović, Miloš and Milanović, Slađan and Filipović, Saša",
year = "2021",
abstract = "Associative memory (AM) reflects the ability to remember and retrieve multiple pieces of information bound together thus enabling complex episodic experiences. Despite growing interest in the use of transcranial direct current stimulation (tDCS) for the modulation of AM, there are inconsistent evidence regarding its benefits. An alternative to standard constant tDCS could be the application of frequency-modulated tDCS protocols, that mimic natural function-relevant brain rhythms. Here, we show the effects of anodal tDCS oscillating in theta rhythm (5 Hz; 1.5 ± 0.1 mA) versus constant anodal tDCS and sham over left posterior parietal cortex on cued recall of face-word associations. In a crossover design, each participant completed AM assessment immediately following 20-min theta-oscillatory, constant, and sham tDCS, as well as 1 and 5 days after. Theta oscillatory tDCS increased initial AM performance in comparison to sham, and so did constant tDCS. On the group level, no differences between oscillatory and constant tDCS were observed, but individual-level analysis revealed that some participants responded to theta-oscillatory but not to constant tDCS, and vice versa, which could be attributed to their different physiological modes of action. This study shows the potential of oscillatory tDCS protocols for memory enhancement to produce strong and reliable memory-modulating effects which deserve to be investigated further.",
journal = "Scientific Reports",
title = "Theta-modulated oscillatory transcranial direct current stimulation over posterior parietal cortex improves associative memory",
number = "1",
pages = "3013",
volume = "11",
doi = "10.1038/s41598-021-82577-7"
}

Vulić, K., Bjekić, J., Paunović, D., Jovanović, M., Milanović, S.,& Filipović, S.. (2021). Theta-modulated oscillatory transcranial direct current stimulation over posterior parietal cortex improves associative memory. in Scientific Reports, 11(1), 3013.
https://doi.org/10.1038/s41598-021-82577-7

Vulić K, Bjekić J, Paunović D, Jovanović M, Milanović S, Filipović S. Theta-modulated oscillatory transcranial direct current stimulation over posterior parietal cortex improves associative memory. in Scientific Reports. 2021;11(1):3013.
doi:10.1038/s41598-021-82577-7 .

Vulić, Katarina, Bjekić, Jovana, Paunović, Dunja, Jovanović, Miloš, Milanović, Slađan, Filipović, Saša, "Theta-modulated oscillatory transcranial direct current stimulation over posterior parietal cortex improves associative memory" in Scientific Reports, 11, no. 1 (2021):3013,
https://doi.org/10.1038/s41598-021-82577-7 . .

TY  - JOUR
AU  - Filipović, Saša
AU  - Kačar, Aleksandra
AU  - Milanović, Slađan
AU  - Ljubisavljević, Miloš
PY  - 2021
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1194
AB  - Background: Although dopaminergic medication has been the foundation of Parkinson's disease (PD) therapy for decades, sensitive and specific therapeutic response biomarkers that allow for better treatment optimization are lacking. Objective: We tested whether the features of Transcranial Magnetic Stimulation-based neurophysiological measures taken off-medication are associated with dopaminergic medication-induced clinical effects. Method: Motor cortex excitability [short-latency intracortical inhibition (SICI), intracortical facilitation (ICF), short-latency afferent inhibition (SAI), and input-output (IO) curve], and plasticity [paired associative stimulation (PAS) protocol] neurophysiological measures were examined in 23 PD patients off-medication. Clinical features were quantified by the motor section of the Unified Parkinson's Disease Scale (total score and lateralized total, bradykinesia, and rigidity sub-scores), and the differences between measures off-medication and on-medication (following the usual morning dose), were determined. Total daily dopaminergic medication dose (expressed as levodopa equivalent daily dose-LEDD), was also determined. Results: SICI significantly correlated with changes in lateralized UPDRS motor and bradykinesia sub-scores, suggesting that patients with stronger basal intracortical inhibition benefit more from dopaminergic treatment than patients with weaker intracortical inhibition. Also, ICF significantly negatively correlated with LEDD, suggesting that patients with stronger intracortical facilitation require less dopaminergic medication to achieve optimal therapeutic benefit. Both associations were independent of disease severity and duration. Conclusions: The results suggest variability of (patho) physiological phenotypes related to intracortical inhibitory and facilitatory mechanisms determining clinical response to dopaminergic medication in PD. Measures of intracortical excitability may help predict patients' response to dopaminergic therapy, thus potentially providing a background for developing personalized therapy in PD.
PB  - Frontiers Media S.A.
T2  - Frontiers in Neurology
T1  - Neurophysiological Predictors of Response to Medication in Parkinson's Disease
SP  - 763911
VL  - 12
DO  - 10.3389/fneur.2021.763911
ER  - 

@article{
author = "Filipović, Saša and Kačar, Aleksandra and Milanović, Slađan and Ljubisavljević, Miloš",
year = "2021",
abstract = "Background: Although dopaminergic medication has been the foundation of Parkinson's disease (PD) therapy for decades, sensitive and specific therapeutic response biomarkers that allow for better treatment optimization are lacking. Objective: We tested whether the features of Transcranial Magnetic Stimulation-based neurophysiological measures taken off-medication are associated with dopaminergic medication-induced clinical effects. Method: Motor cortex excitability [short-latency intracortical inhibition (SICI), intracortical facilitation (ICF), short-latency afferent inhibition (SAI), and input-output (IO) curve], and plasticity [paired associative stimulation (PAS) protocol] neurophysiological measures were examined in 23 PD patients off-medication. Clinical features were quantified by the motor section of the Unified Parkinson's Disease Scale (total score and lateralized total, bradykinesia, and rigidity sub-scores), and the differences between measures off-medication and on-medication (following the usual morning dose), were determined. Total daily dopaminergic medication dose (expressed as levodopa equivalent daily dose-LEDD), was also determined. Results: SICI significantly correlated with changes in lateralized UPDRS motor and bradykinesia sub-scores, suggesting that patients with stronger basal intracortical inhibition benefit more from dopaminergic treatment than patients with weaker intracortical inhibition. Also, ICF significantly negatively correlated with LEDD, suggesting that patients with stronger intracortical facilitation require less dopaminergic medication to achieve optimal therapeutic benefit. Both associations were independent of disease severity and duration. Conclusions: The results suggest variability of (patho) physiological phenotypes related to intracortical inhibitory and facilitatory mechanisms determining clinical response to dopaminergic medication in PD. Measures of intracortical excitability may help predict patients' response to dopaminergic therapy, thus potentially providing a background for developing personalized therapy in PD.",
publisher = "Frontiers Media S.A.",
journal = "Frontiers in Neurology",
title = "Neurophysiological Predictors of Response to Medication in Parkinson's Disease",
pages = "763911",
volume = "12",
doi = "10.3389/fneur.2021.763911"
}

Filipović, S., Kačar, A., Milanović, S.,& Ljubisavljević, M.. (2021). Neurophysiological Predictors of Response to Medication in Parkinson's Disease. in Frontiers in Neurology
Frontiers Media S.A.., 12, 763911.
https://doi.org/10.3389/fneur.2021.763911

Filipović S, Kačar A, Milanović S, Ljubisavljević M. Neurophysiological Predictors of Response to Medication in Parkinson's Disease. in Frontiers in Neurology. 2021;12:763911.
doi:10.3389/fneur.2021.763911 .

Filipović, Saša, Kačar, Aleksandra, Milanović, Slađan, Ljubisavljević, Miloš, "Neurophysiological Predictors of Response to Medication in Parkinson's Disease" in Frontiers in Neurology, 12 (2021):763911,
https://doi.org/10.3389/fneur.2021.763911 . .

TY  - JOUR
AU  - Bjekić, Jovana
AU  - Živanović, Marko
AU  - Filipović, Saša
PY  - 2021
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1266
AB  - Memory enhancement is one of the great challenges in cognitive neuroscience and neurorehabilitation. Among various techniques used for memory enhancement, transcranial direct current stimulation (tDCS) is emerging as an especially promising tool for improvement of memory functions in a non-invasive manner. Here, we present a tDCS protocol that can be applied for memory enhancement in healthy-participant studies as well as in aging and dementia research. The protocol uses weak constant anodal current to stimulate cortical targets within cortico-hippocampal functional network engaged in memory processes. The target electrode is placed either on the posterior parietal cortex (PPC) or the dorsolateral prefrontal cortex (DLPFC), while the return electrode is placed extracranially (i.e., on the contralateral cheek). In addition, we outline a more advanced method of oscillatory tDCS, mimicking a natural brain rhythm to promote hippocampus-dependent memory functions, which can be applied in a personalized and non-personalized manner. We present illustrative results of associative and working memory improvement following single tDCS sessions (20 minutes) in which the described electrode montages were used with current intensities between 1.5 mA and 1.8 mA. Finally, we discuss crucial steps in the protocol and methodological decisions that must be made when designing a tDCS study on memory.
T2  - Journal of Visualized Experiments
T1  - Transcranial direct current stimulation (Tdcs) for memory enhancement
IS  - 175
SP  - e62681
VL  - 2021
DO  - 10.3791/62681
ER  - 

@article{
author = "Bjekić, Jovana and Živanović, Marko and Filipović, Saša",
year = "2021",
abstract = "Memory enhancement is one of the great challenges in cognitive neuroscience and neurorehabilitation. Among various techniques used for memory enhancement, transcranial direct current stimulation (tDCS) is emerging as an especially promising tool for improvement of memory functions in a non-invasive manner. Here, we present a tDCS protocol that can be applied for memory enhancement in healthy-participant studies as well as in aging and dementia research. The protocol uses weak constant anodal current to stimulate cortical targets within cortico-hippocampal functional network engaged in memory processes. The target electrode is placed either on the posterior parietal cortex (PPC) or the dorsolateral prefrontal cortex (DLPFC), while the return electrode is placed extracranially (i.e., on the contralateral cheek). In addition, we outline a more advanced method of oscillatory tDCS, mimicking a natural brain rhythm to promote hippocampus-dependent memory functions, which can be applied in a personalized and non-personalized manner. We present illustrative results of associative and working memory improvement following single tDCS sessions (20 minutes) in which the described electrode montages were used with current intensities between 1.5 mA and 1.8 mA. Finally, we discuss crucial steps in the protocol and methodological decisions that must be made when designing a tDCS study on memory.",
journal = "Journal of Visualized Experiments",
title = "Transcranial direct current stimulation (Tdcs) for memory enhancement",
number = "175",
pages = "e62681",
volume = "2021",
doi = "10.3791/62681"
}

Bjekić, J., Živanović, M.,& Filipović, S.. (2021). Transcranial direct current stimulation (Tdcs) for memory enhancement. in Journal of Visualized Experiments, 2021(175), e62681.
https://doi.org/10.3791/62681

Bjekić J, Živanović M, Filipović S. Transcranial direct current stimulation (Tdcs) for memory enhancement. in Journal of Visualized Experiments. 2021;2021(175):e62681.
doi:10.3791/62681 .

Bjekić, Jovana, Živanović, Marko, Filipović, Saša, "Transcranial direct current stimulation (Tdcs) for memory enhancement" in Journal of Visualized Experiments, 2021, no. 175 (2021):e62681,
https://doi.org/10.3791/62681 . .

TY  - JOUR
AU  - Lefaucheur, Jean-Pascal
AU  - Aleman, Andre
AU  - Baeken, Chris
AU  - Benninger, David H.
AU  - Brunelin, Jerome
AU  - Di Lazzaro, Vincenzo
AU  - Filipović, Saša
AU  - Grefkes, Christian
AU  - Hasan, Alkomiet
AU  - Hummel, Friedhelm C.
AU  - Jaaskelainen, Satu K.
AU  - Langguth, Berthold
AU  - Leocani, Letizia
AU  - Londero, Alain
AU  - Nardone, Raffaele
AU  - Nguyen, Jean-Paul
AU  - Nyffeler, Thomas
AU  - Oliveira-Maia, Albino J.
AU  - Oliviero, Antonio
AU  - Padberg, Frank
AU  - Palm, Ulrich
AU  - Paulus, Walter
AU  - Poulet, Emmanuel
AU  - Quartarone, Angelo
AU  - Rachid, Fady
AU  - Rektorova, Irena
AU  - Rossi, Simone
AU  - Sahlsten, Hanna
AU  - Schecklmann, Martin
AU  - Szekely, David
AU  - Ziemann, Ulf
PY  - 2020
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1032
AB  - A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018. Level A evidence (definite efficacy) was reached for: high-frequency (HF) rTMS of the primary motor cortex (M1) contralateral to the painful side for neuropathic pain; HF-rTMS of the left dorsolateral prefrontal cortex (DLPFC) using a figure-of-8 or a Hl-coil for depression; low-frequency (LF) rTMS of contralesional M1 for hand motor recovery in the post-acute stage of stroke. Level B evidence (probable efficacy) was reached for: HF-rTMS of the left M1 or DLPFC for improving quality of life or pain, respectively, in fibromyalgia; HF-rTMS of bilateral M1 regions or the left DLPFC for improving motor impairment or depression, respectively, in Parkinson's disease; HF-rTMS of ipsilesional M1 for promoting motor recovery at the post-acute stage of stroke; intermittent theta burst stimulation targeted to the leg motor cortex for lower limb spasticity in multiple sclerosis; HF-rTMS of the right DLPFC in posttraumatic stress disorder; LF-rTMS of the right inferior frontal gyrus in chronic post-stroke non-fluent aphasia; LF-rTMS of the right DLPFC in depression; and bihemispheric stimulation of the DLPFC combining right-sided LF-rTMS (or continuous theta burst stimulation) and left-sided HF-rTMS (or intermittent theta burst stimulation) in depression. Level A/B evidence is not reached concerning efficacy of rTMS in any other condition. The current recommendations are based on the differences reached in therapeutic efficacy of real vs. sham rTMS protocols, replicated in a sufficient number of independent studies. This does not mean that the benefit produced by rTMS inevitably reaches a level of clinical relevance.
PB  - Elsevier Ireland Ltd, Clare
T2  - Clinical Neurophysiology
T1  - Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)
EP  - 528
IS  - 2
SP  - 474
VL  - 131
DO  - 10.1016/j.clinph.2019.11.002
ER  - 

@article{
author = "Lefaucheur, Jean-Pascal and Aleman, Andre and Baeken, Chris and Benninger, David H. and Brunelin, Jerome and Di Lazzaro, Vincenzo and Filipović, Saša and Grefkes, Christian and Hasan, Alkomiet and Hummel, Friedhelm C. and Jaaskelainen, Satu K. and Langguth, Berthold and Leocani, Letizia and Londero, Alain and Nardone, Raffaele and Nguyen, Jean-Paul and Nyffeler, Thomas and Oliveira-Maia, Albino J. and Oliviero, Antonio and Padberg, Frank and Palm, Ulrich and Paulus, Walter and Poulet, Emmanuel and Quartarone, Angelo and Rachid, Fady and Rektorova, Irena and Rossi, Simone and Sahlsten, Hanna and Schecklmann, Martin and Szekely, David and Ziemann, Ulf",
year = "2020",
abstract = "A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018. Level A evidence (definite efficacy) was reached for: high-frequency (HF) rTMS of the primary motor cortex (M1) contralateral to the painful side for neuropathic pain; HF-rTMS of the left dorsolateral prefrontal cortex (DLPFC) using a figure-of-8 or a Hl-coil for depression; low-frequency (LF) rTMS of contralesional M1 for hand motor recovery in the post-acute stage of stroke. Level B evidence (probable efficacy) was reached for: HF-rTMS of the left M1 or DLPFC for improving quality of life or pain, respectively, in fibromyalgia; HF-rTMS of bilateral M1 regions or the left DLPFC for improving motor impairment or depression, respectively, in Parkinson's disease; HF-rTMS of ipsilesional M1 for promoting motor recovery at the post-acute stage of stroke; intermittent theta burst stimulation targeted to the leg motor cortex for lower limb spasticity in multiple sclerosis; HF-rTMS of the right DLPFC in posttraumatic stress disorder; LF-rTMS of the right inferior frontal gyrus in chronic post-stroke non-fluent aphasia; LF-rTMS of the right DLPFC in depression; and bihemispheric stimulation of the DLPFC combining right-sided LF-rTMS (or continuous theta burst stimulation) and left-sided HF-rTMS (or intermittent theta burst stimulation) in depression. Level A/B evidence is not reached concerning efficacy of rTMS in any other condition. The current recommendations are based on the differences reached in therapeutic efficacy of real vs. sham rTMS protocols, replicated in a sufficient number of independent studies. This does not mean that the benefit produced by rTMS inevitably reaches a level of clinical relevance.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Clinical Neurophysiology",
title = "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)",
pages = "528-474",
number = "2",
volume = "131",
doi = "10.1016/j.clinph.2019.11.002"
}

Lefaucheur, J., Aleman, A., Baeken, C., Benninger, D. H., Brunelin, J., Di Lazzaro, V., Filipović, S., Grefkes, C., Hasan, A., Hummel, F. C., Jaaskelainen, S. K., Langguth, B., Leocani, L., Londero, A., Nardone, R., Nguyen, J., Nyffeler, T., Oliveira-Maia, A. J., Oliviero, A., Padberg, F., Palm, U., Paulus, W., Poulet, E., Quartarone, A., Rachid, F., Rektorova, I., Rossi, S., Sahlsten, H., Schecklmann, M., Szekely, D.,& Ziemann, U.. (2020). Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018). in Clinical Neurophysiology
Elsevier Ireland Ltd, Clare., 131(2), 474-528.
https://doi.org/10.1016/j.clinph.2019.11.002

Lefaucheur J, Aleman A, Baeken C, Benninger DH, Brunelin J, Di Lazzaro V, Filipović S, Grefkes C, Hasan A, Hummel FC, Jaaskelainen SK, Langguth B, Leocani L, Londero A, Nardone R, Nguyen J, Nyffeler T, Oliveira-Maia AJ, Oliviero A, Padberg F, Palm U, Paulus W, Poulet E, Quartarone A, Rachid F, Rektorova I, Rossi S, Sahlsten H, Schecklmann M, Szekely D, Ziemann U. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018). in Clinical Neurophysiology. 2020;131(2):474-528.
doi:10.1016/j.clinph.2019.11.002 .

Lefaucheur, Jean-Pascal, Aleman, Andre, Baeken, Chris, Benninger, David H., Brunelin, Jerome, Di Lazzaro, Vincenzo, Filipović, Saša, Grefkes, Christian, Hasan, Alkomiet, Hummel, Friedhelm C., Jaaskelainen, Satu K., Langguth, Berthold, Leocani, Letizia, Londero, Alain, Nardone, Raffaele, Nguyen, Jean-Paul, Nyffeler, Thomas, Oliveira-Maia, Albino J., Oliviero, Antonio, Padberg, Frank, Palm, Ulrich, Paulus, Walter, Poulet, Emmanuel, Quartarone, Angelo, Rachid, Fady, Rektorova, Irena, Rossi, Simone, Sahlsten, Hanna, Schecklmann, Martin, Szekely, David, Ziemann, Ulf, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)" in Clinical Neurophysiology, 131, no. 2 (2020):474-528,
https://doi.org/10.1016/j.clinph.2019.11.002 . .

TY  - JOUR
AU  - Lefaucheur, Jean-Pascal
AU  - Aleman, Andre
AU  - Baeken, Chris
AU  - Benninger, David H.
AU  - Brunelin, Jerome
AU  - Di Lazzaro, Vincenzo
AU  - Filipović, Saša
AU  - Grefkes, Christian
AU  - Hasan, Alkomiet
AU  - Hummel, Friedhelm C.
AU  - Jaaskelainen, Satu K.
AU  - Langguth, Berthold
AU  - Leocani, Letizia
AU  - Londero, Alain
AU  - Nardone, Raffaele
AU  - Nguyen, Jean-Paul
AU  - Nyffeler, Thomas
AU  - Oliveira-Maia, Albino J.
AU  - Oliviero, Antonio
AU  - Padberg, Frank
AU  - Palm, Ulrich
AU  - Paulus, Walter
AU  - Poulet, Emmanuel
AU  - Quartarone, Angelo
AU  - Rachid, Fady
AU  - Rektorova, Irena
AU  - Rossi, Simone
AU  - Sahlsten, Hanna
AU  - Schecklmann, Martin
AU  - Szekely, David
AU  - Ziemann, Ulf
PY  - 2020
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1054
PB  - Elsevier Ireland Ltd, Clare
T2  - Clinical Neurophysiology
T1  - Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018) (vol 131, pg 474, 2020)
EP  - 1169
IS  - 5
SP  - 1168
VL  - 131
DO  - 10.1016/j.clinph.2020.02.003
ER  - 

@article{
author = "Lefaucheur, Jean-Pascal and Aleman, Andre and Baeken, Chris and Benninger, David H. and Brunelin, Jerome and Di Lazzaro, Vincenzo and Filipović, Saša and Grefkes, Christian and Hasan, Alkomiet and Hummel, Friedhelm C. and Jaaskelainen, Satu K. and Langguth, Berthold and Leocani, Letizia and Londero, Alain and Nardone, Raffaele and Nguyen, Jean-Paul and Nyffeler, Thomas and Oliveira-Maia, Albino J. and Oliviero, Antonio and Padberg, Frank and Palm, Ulrich and Paulus, Walter and Poulet, Emmanuel and Quartarone, Angelo and Rachid, Fady and Rektorova, Irena and Rossi, Simone and Sahlsten, Hanna and Schecklmann, Martin and Szekely, David and Ziemann, Ulf",
year = "2020",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Clinical Neurophysiology",
title = "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018) (vol 131, pg 474, 2020)",
pages = "1169-1168",
number = "5",
volume = "131",
doi = "10.1016/j.clinph.2020.02.003"
}

Lefaucheur, J., Aleman, A., Baeken, C., Benninger, D. H., Brunelin, J., Di Lazzaro, V., Filipović, S., Grefkes, C., Hasan, A., Hummel, F. C., Jaaskelainen, S. K., Langguth, B., Leocani, L., Londero, A., Nardone, R., Nguyen, J., Nyffeler, T., Oliveira-Maia, A. J., Oliviero, A., Padberg, F., Palm, U., Paulus, W., Poulet, E., Quartarone, A., Rachid, F., Rektorova, I., Rossi, S., Sahlsten, H., Schecklmann, M., Szekely, D.,& Ziemann, U.. (2020). Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018) (vol 131, pg 474, 2020). in Clinical Neurophysiology
Elsevier Ireland Ltd, Clare., 131(5), 1168-1169.
https://doi.org/10.1016/j.clinph.2020.02.003

Lefaucheur J, Aleman A, Baeken C, Benninger DH, Brunelin J, Di Lazzaro V, Filipović S, Grefkes C, Hasan A, Hummel FC, Jaaskelainen SK, Langguth B, Leocani L, Londero A, Nardone R, Nguyen J, Nyffeler T, Oliveira-Maia AJ, Oliviero A, Padberg F, Palm U, Paulus W, Poulet E, Quartarone A, Rachid F, Rektorova I, Rossi S, Sahlsten H, Schecklmann M, Szekely D, Ziemann U. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018) (vol 131, pg 474, 2020). in Clinical Neurophysiology. 2020;131(5):1168-1169.
doi:10.1016/j.clinph.2020.02.003 .

Lefaucheur, Jean-Pascal, Aleman, Andre, Baeken, Chris, Benninger, David H., Brunelin, Jerome, Di Lazzaro, Vincenzo, Filipović, Saša, Grefkes, Christian, Hasan, Alkomiet, Hummel, Friedhelm C., Jaaskelainen, Satu K., Langguth, Berthold, Leocani, Letizia, Londero, Alain, Nardone, Raffaele, Nguyen, Jean-Paul, Nyffeler, Thomas, Oliveira-Maia, Albino J., Oliviero, Antonio, Padberg, Frank, Palm, Ulrich, Paulus, Walter, Poulet, Emmanuel, Quartarone, Angelo, Rachid, Fady, Rektorova, Irena, Rossi, Simone, Sahlsten, Hanna, Schecklmann, Martin, Szekely, David, Ziemann, Ulf, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018) (vol 131, pg 474, 2020)" in Clinical Neurophysiology, 131, no. 5 (2020):1168-1169,
https://doi.org/10.1016/j.clinph.2020.02.003 . .

TY  - CONF
AU  - Filipović, Saša
AU  - Knežević, T.
AU  - Rodić, S.
AU  - Milanović, Slađan
AU  - Drulović, Jelena
AU  - Konstantinović, Ljubica
PY  - 2020
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1065
PB  - Wiley, Hoboken
C3  - European Journal of Neurology
T1  - Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems
EP  - 1016
SP  - 1016
VL  - 27
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1065
ER  - 

@conference{
author = "Filipović, Saša and Knežević, T. and Rodić, S. and Milanović, Slađan and Drulović, Jelena and Konstantinović, Ljubica",
year = "2020",
publisher = "Wiley, Hoboken",
journal = "European Journal of Neurology",
title = "Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems",
pages = "1016-1016",
volume = "27",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1065"
}

Filipović, S., Knežević, T., Rodić, S., Milanović, S., Drulović, J.,& Konstantinović, L.. (2020). Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems. in European Journal of Neurology
Wiley, Hoboken., 27, 1016-1016.
https://hdl.handle.net/21.15107/rcub_rimi_1065

Filipović S, Knežević T, Rodić S, Milanović S, Drulović J, Konstantinović L. Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems. in European Journal of Neurology. 2020;27:1016-1016.
https://hdl.handle.net/21.15107/rcub_rimi_1065 .

Filipović, Saša, Knežević, T., Rodić, S., Milanović, Slađan, Drulović, Jelena, Konstantinović, Ljubica, "Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems" in European Journal of Neurology, 27 (2020):1016-1016,
https://hdl.handle.net/21.15107/rcub_rimi_1065 .

TY  - JOUR
AU  - Stevanović, Vuk
AU  - Jelić, Milan
AU  - Milanović, Slađan
AU  - Filipović, Saša
AU  - Mikić, Mladen J.
AU  - Stojanović, Marko D. M.
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/918
AB  - The purpose of this study was to examine the acute effects of static stretching (SS) and dynamic stretching (DS), alone and in combination with specific basketball warm-up (SBWU), on the neuromuscular excitability and vertical jump height in basketball players. Twelve healthy young male basketball players participated in the study (18 +/- 0.42 years; 17.4 - 18.6 age range; 188 +/- 9 cm; 76.5 +/- 9 kg). All participants completed two different stretching treatments (static and dynamic), performed on different days at least seven days apart, in the same period of training microcycle, in a counterbalanced order. Each session consisted of a self-paced jogging warm-up, followed by a 10-minute testing period (T0), which involved eliciting H reflex and M waves, followed by three trials of a vertical jump test. Participants then performed one of the treatment protocols. After another test (T1), participants conducted 8-minute specific basketball warm-up and then one more test (T2). Combined 3 (time) x 2 (stretching protocol) analysis of variance with repeated measures on both factors revealed that SS significantly decreased spinal excitability (H/M ratio) (p = 0.015, d = -0.38, percentage of change = -20.55%) and vertical jump height (p = 0.007, d = -1.91, percentage of change = -2.6%), but after SBWU, vertical jump height increased (p = 0.006, d = 1.13, percentage of change = 3.01%), while H/M ratio continued decreasing (p = 0.019, d = -0.45, percentage of change = -30.23%). Acute effects of DS, alone and in combination with SBWU were not significant. It seems that SBWU attenuates negative acute effects of SS on vertical jump performance in young basketball players, while DS appears to cause no significant acute effect for this population.
PB  - Journal Sports Science & Medicine, Bursa
T2  - Journal of Sports Science & Medicine
T1  - Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players
EP  - 289
IS  - 2
SP  - 282
VL  - 18
UR  - https://hdl.handle.net/21.15107/rcub_rimi_918
ER  - 

@article{
author = "Stevanović, Vuk and Jelić, Milan and Milanović, Slađan and Filipović, Saša and Mikić, Mladen J. and Stojanović, Marko D. M.",
year = "2019",
abstract = "The purpose of this study was to examine the acute effects of static stretching (SS) and dynamic stretching (DS), alone and in combination with specific basketball warm-up (SBWU), on the neuromuscular excitability and vertical jump height in basketball players. Twelve healthy young male basketball players participated in the study (18 +/- 0.42 years; 17.4 - 18.6 age range; 188 +/- 9 cm; 76.5 +/- 9 kg). All participants completed two different stretching treatments (static and dynamic), performed on different days at least seven days apart, in the same period of training microcycle, in a counterbalanced order. Each session consisted of a self-paced jogging warm-up, followed by a 10-minute testing period (T0), which involved eliciting H reflex and M waves, followed by three trials of a vertical jump test. Participants then performed one of the treatment protocols. After another test (T1), participants conducted 8-minute specific basketball warm-up and then one more test (T2). Combined 3 (time) x 2 (stretching protocol) analysis of variance with repeated measures on both factors revealed that SS significantly decreased spinal excitability (H/M ratio) (p = 0.015, d = -0.38, percentage of change = -20.55%) and vertical jump height (p = 0.007, d = -1.91, percentage of change = -2.6%), but after SBWU, vertical jump height increased (p = 0.006, d = 1.13, percentage of change = 3.01%), while H/M ratio continued decreasing (p = 0.019, d = -0.45, percentage of change = -30.23%). Acute effects of DS, alone and in combination with SBWU were not significant. It seems that SBWU attenuates negative acute effects of SS on vertical jump performance in young basketball players, while DS appears to cause no significant acute effect for this population.",
publisher = "Journal Sports Science & Medicine, Bursa",
journal = "Journal of Sports Science & Medicine",
title = "Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players",
pages = "289-282",
number = "2",
volume = "18",
url = "https://hdl.handle.net/21.15107/rcub_rimi_918"
}

Stevanović, V., Jelić, M., Milanović, S., Filipović, S., Mikić, M. J.,& Stojanović, M. D. M.. (2019). Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players. in Journal of Sports Science & Medicine
Journal Sports Science & Medicine, Bursa., 18(2), 282-289.
https://hdl.handle.net/21.15107/rcub_rimi_918

Stevanović V, Jelić M, Milanović S, Filipović S, Mikić MJ, Stojanović MDM. Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players. in Journal of Sports Science & Medicine. 2019;18(2):282-289.
https://hdl.handle.net/21.15107/rcub_rimi_918 .

Stevanović, Vuk, Jelić, Milan, Milanović, Slađan, Filipović, Saša, Mikić, Mladen J., Stojanović, Marko D. M., "Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players" in Journal of Sports Science & Medicine, 18, no. 2 (2019):282-289,
https://hdl.handle.net/21.15107/rcub_rimi_918 .

TY  - JOUR
AU  - Bjekić, Jovana
AU  - Čolić, Marija V.
AU  - Živanović, Marko
AU  - Milanović, Slađan
AU  - Filipović, Saša
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/943
AB  - Associative memory plays a key role in everyday functioning, but it declines with normal ageing as well as due to various pathological states and conditions, thus impairing quality of life. Associative memory enhancement via neurostimulation over frontal areas resulted in limited success, while posterior stimulation sites seemed to be more promising. We hypothesized that anodal transcranial direct current stimulation (tDCS) of parietal areas would lead to higher performance in associative memory due to high connectivity between posterior parietal cortex (PPC) and hippocampus. Forty-two healthy adults participated in two sham-controlled cross-over experiments. Anodal electrode (20 min, 1.5 mA) was placed over P3 in Experiment 1 and over P4 in Experiment 2. During tDCS participants played a simple computer game. After each stimulation session, participants completed parallel forms of an associative memory task (Experiment 1: face-word memory; Experiment 2: object-location memory) and a control task (verbal fluency). In both experiments, associative memory was improved after anodal stimulation compared to sham stimulation, while no differences were observed in the control task. Additionally, memory performance was higher in the second than in the first trial, but the increase in performance between the two trials did not differ between stimulation conditions. It can be concluded that a single-session anodal tDCS over posterior parietal cortex can improve associative memory performance. The specificity, robustness, and reproducibility of the effect suggest that PPC is a promising target for brain stimulation aiming to enhance memory functions.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Neurobiology of Learning & Memory
T1  - Transcranial direct current stimulation (tDCS) over parietal cortex improves associative memory
EP  - 120
SP  - 114
VL  - 157
DO  - 10.1016/j.nlm.2018.12.007
ER  - 

@article{
author = "Bjekić, Jovana and Čolić, Marija V. and Živanović, Marko and Milanović, Slađan and Filipović, Saša",
year = "2019",
abstract = "Associative memory plays a key role in everyday functioning, but it declines with normal ageing as well as due to various pathological states and conditions, thus impairing quality of life. Associative memory enhancement via neurostimulation over frontal areas resulted in limited success, while posterior stimulation sites seemed to be more promising. We hypothesized that anodal transcranial direct current stimulation (tDCS) of parietal areas would lead to higher performance in associative memory due to high connectivity between posterior parietal cortex (PPC) and hippocampus. Forty-two healthy adults participated in two sham-controlled cross-over experiments. Anodal electrode (20 min, 1.5 mA) was placed over P3 in Experiment 1 and over P4 in Experiment 2. During tDCS participants played a simple computer game. After each stimulation session, participants completed parallel forms of an associative memory task (Experiment 1: face-word memory; Experiment 2: object-location memory) and a control task (verbal fluency). In both experiments, associative memory was improved after anodal stimulation compared to sham stimulation, while no differences were observed in the control task. Additionally, memory performance was higher in the second than in the first trial, but the increase in performance between the two trials did not differ between stimulation conditions. It can be concluded that a single-session anodal tDCS over posterior parietal cortex can improve associative memory performance. The specificity, robustness, and reproducibility of the effect suggest that PPC is a promising target for brain stimulation aiming to enhance memory functions.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Neurobiology of Learning & Memory",
title = "Transcranial direct current stimulation (tDCS) over parietal cortex improves associative memory",
pages = "120-114",
volume = "157",
doi = "10.1016/j.nlm.2018.12.007"
}

Bjekić, J., Čolić, M. V., Živanović, M., Milanović, S.,& Filipović, S.. (2019). Transcranial direct current stimulation (tDCS) over parietal cortex improves associative memory. in Neurobiology of Learning & Memory
Academic Press Inc Elsevier Science, San Diego., 157, 114-120.
https://doi.org/10.1016/j.nlm.2018.12.007

Bjekić J, Čolić MV, Živanović M, Milanović S, Filipović S. Transcranial direct current stimulation (tDCS) over parietal cortex improves associative memory. in Neurobiology of Learning & Memory. 2019;157:114-120.
doi:10.1016/j.nlm.2018.12.007 .

Bjekić, Jovana, Čolić, Marija V., Živanović, Marko, Milanović, Slađan, Filipović, Saša, "Transcranial direct current stimulation (tDCS) over parietal cortex improves associative memory" in Neurobiology of Learning & Memory, 157 (2019):114-120,
https://doi.org/10.1016/j.nlm.2018.12.007 . .

TY  - JOUR
AU  - Ljubisavljević, Miloš
AU  - Oommen, Joji
AU  - Filipović, Saša
AU  - Bjekić, Jovana
AU  - Szolics, Miklos
AU  - Nagelkerke, Nico
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/965
AB  - Healthy aging limits the activities of daily living and personal independence. Furthermore, cognitive-motor interference in dual-task (e.g., walking while talking) appears to be more pronounced in the elderly. Transcranial direct current stimulation (tDCS), a form of the non-invasive brain stimulation technique, is known to modify cortical excitability and has been investigated as a tool for enhancing motor and cognitive performance in health and disease. The present study examined whether tDCS targeting the dorsolateral prefrontal cortex (DLPFC) could improve dual-task performance in healthy older adults. The effects of tDCS, among other factors, depend on stimulation polarity (anodel vs. cathodal), electrode setup (unilateral vs. bilateral) and the time of application (off-line vs. on-line). We therefore explored the effects of unilateral and simultaneous bilateral tDCS (anodel and cathodal) of left DLPFC while performing (on-line) the Grooved Pegboard Test (GPT) and Serial Seven Subtraction Test (SSST) alone or together (dual-tasking). The number of pegs and the number of correct subtractions were recorded before, during and 30 min after tDCS. The dual-task performance was measured as the percent change from single- to the dual-task condition (dual-task cost DTC). Only bilateral, anode left tDCS, induced a significant increase in subtracted numbers while dual-tasking, i.e., it reduced the DTC of manual dexterity (GPT) to a cognitive task. Significant changes 30 min after the stimulation were only present after bilateral anode right (BAR) tDCS on GPT dual-task costs. These findings suggest that anodal tDCS applied on-line interacts with a dual-task performance involving demanding cognitive and manual dexterity tasks. The results support the potential use of non-invasive brain stimulation for improvement of cognitive functioning in daily activities in older individuals.
PB  - Frontiers Media Sa, Lausanne
T2  - Frontiers in Aging Neuroscience
T1  - Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults
VL  - 11
DO  - 10.3389/fnagi.2019.00144
ER  - 

@article{
author = "Ljubisavljević, Miloš and Oommen, Joji and Filipović, Saša and Bjekić, Jovana and Szolics, Miklos and Nagelkerke, Nico",
year = "2019",
abstract = "Healthy aging limits the activities of daily living and personal independence. Furthermore, cognitive-motor interference in dual-task (e.g., walking while talking) appears to be more pronounced in the elderly. Transcranial direct current stimulation (tDCS), a form of the non-invasive brain stimulation technique, is known to modify cortical excitability and has been investigated as a tool for enhancing motor and cognitive performance in health and disease. The present study examined whether tDCS targeting the dorsolateral prefrontal cortex (DLPFC) could improve dual-task performance in healthy older adults. The effects of tDCS, among other factors, depend on stimulation polarity (anodel vs. cathodal), electrode setup (unilateral vs. bilateral) and the time of application (off-line vs. on-line). We therefore explored the effects of unilateral and simultaneous bilateral tDCS (anodel and cathodal) of left DLPFC while performing (on-line) the Grooved Pegboard Test (GPT) and Serial Seven Subtraction Test (SSST) alone or together (dual-tasking). The number of pegs and the number of correct subtractions were recorded before, during and 30 min after tDCS. The dual-task performance was measured as the percent change from single- to the dual-task condition (dual-task cost DTC). Only bilateral, anode left tDCS, induced a significant increase in subtracted numbers while dual-tasking, i.e., it reduced the DTC of manual dexterity (GPT) to a cognitive task. Significant changes 30 min after the stimulation were only present after bilateral anode right (BAR) tDCS on GPT dual-task costs. These findings suggest that anodal tDCS applied on-line interacts with a dual-task performance involving demanding cognitive and manual dexterity tasks. The results support the potential use of non-invasive brain stimulation for improvement of cognitive functioning in daily activities in older individuals.",
publisher = "Frontiers Media Sa, Lausanne",
journal = "Frontiers in Aging Neuroscience",
title = "Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults",
volume = "11",
doi = "10.3389/fnagi.2019.00144"
}

Ljubisavljević, M., Oommen, J., Filipović, S., Bjekić, J., Szolics, M.,& Nagelkerke, N.. (2019). Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults. in Frontiers in Aging Neuroscience
Frontiers Media Sa, Lausanne., 11.
https://doi.org/10.3389/fnagi.2019.00144

Ljubisavljević M, Oommen J, Filipović S, Bjekić J, Szolics M, Nagelkerke N. Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults. in Frontiers in Aging Neuroscience. 2019;11.
doi:10.3389/fnagi.2019.00144 .

Ljubisavljević, Miloš, Oommen, Joji, Filipović, Saša, Bjekić, Jovana, Szolics, Miklos, Nagelkerke, Nico, "Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults" in Frontiers in Aging Neuroscience, 11 (2019),
https://doi.org/10.3389/fnagi.2019.00144 . .