TY  - JOUR
AU  - Šarac, Ivana
AU  - Debeljak-Martačić, Jasmina
AU  - Takić, Marija
AU  - Stevanović, Vuk
AU  - Milešević, Jelena
AU  - Zeković, Milica
AU  - Popović, Tamara B.
AU  - Jovanović, Jovica
AU  - Kardum Vidović, Nevena
PY  - 2023
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1345
AB  - Introduction: Fatty acids (FAs) composition and desaturase activities can be altered in different metabolic conditions, but the adiposity-independent associations with clinical and biochemical indicators of cardiometabolic risk are still unclear. This study aimed to analyze the associations of FAs composition and estimated desaturase activities with anthropometric, clinical, and biochemical cardiometabolic risk indicators in non-diabetic Serbian women, and to investigate if these associations were independent of the level of adiposity and other confounders.

Methods: In 76 non-diabetic, otherwise healthy Serbian women, aged 24-68 years, with or without metabolic syndrome or obesity (BMI=23.6±5.6 kg/m2), FA composition in erythrocyte phospholipids was measured by gas-liquid chromatography. Desaturase activities were estimated from product/precursor FAs ratios (D9D:16:1n-7/16:0; D6D:20:3n-6/18:2n-6; D5D:20:4n-6/20:3n-6). Correlations were made with anthropometric, biochemical (serum glucose, triacylglycerols, LDL-C, HDL-C, ALT, AST, and their ratios) and clinical (blood pressure) indicators of cardiometabolic risk. Linear regression models were performed to test the independence of these associations.

Results: Estimated desaturase activities and certain FAs were associated with anthropometric, clinical and biochemical indicators of cardiometabolic risk: D9D, D6D, 16:1n-7 and 20:3n-6 were directly associated, while D5D and 18:0 were inversely associated. However, the associations with clinical and biochemical indicators were not independent of the associations with the level of adiposity, since they were lost after controlling for anthropometric indices. After controlling for multiple confounders (age, postmenopausal status, education, smoking, physical activity, dietary macronutrient intakes, use of supplements, alcohol consumption), the level of adiposity was the most significant predictor of desaturase activities and aforementioned FAs levels, and mediated their association with biochemical/clinical indicators. Vice versa, desaturase activities predicted the level of adiposity, but not other components of cardiometabolic risk (if the level of adiposity was accounted). While the associations of anthropometric indices with 16:1n-7, 20:3n-6, 18:0 and D9D and D6D activities were linear, the associations with D5D activity were the inverse U-shaped. The only adiposity-independent association of FAs profiles with the indicators of cardiometabolic risk was a positive association of 20:5n-3 with ALT/AST ratio, which requires further exploration.

Discussion: Additional studies are needed to explore the mechanisms of the observed associations.
PB  - Frontiers Media S.A.
T2  - Frontiers in Nutrition
T1  - Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-diabetic Serbian women: the role of level of adiposity
VL  - 10
DO  - 10.3389/fnut.2023.1065578
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1345
ER  - 

@article{
author = "Šarac, Ivana and Debeljak-Martačić, Jasmina and Takić, Marija and Stevanović, Vuk and Milešević, Jelena and Zeković, Milica and Popović, Tamara B. and Jovanović, Jovica and Kardum Vidović, Nevena",
year = "2023",
abstract = "Introduction: Fatty acids (FAs) composition and desaturase activities can be altered in different metabolic conditions, but the adiposity-independent associations with clinical and biochemical indicators of cardiometabolic risk are still unclear. This study aimed to analyze the associations of FAs composition and estimated desaturase activities with anthropometric, clinical, and biochemical cardiometabolic risk indicators in non-diabetic Serbian women, and to investigate if these associations were independent of the level of adiposity and other confounders.

Methods: In 76 non-diabetic, otherwise healthy Serbian women, aged 24-68 years, with or without metabolic syndrome or obesity (BMI=23.6±5.6 kg/m2), FA composition in erythrocyte phospholipids was measured by gas-liquid chromatography. Desaturase activities were estimated from product/precursor FAs ratios (D9D:16:1n-7/16:0; D6D:20:3n-6/18:2n-6; D5D:20:4n-6/20:3n-6). Correlations were made with anthropometric, biochemical (serum glucose, triacylglycerols, LDL-C, HDL-C, ALT, AST, and their ratios) and clinical (blood pressure) indicators of cardiometabolic risk. Linear regression models were performed to test the independence of these associations.

Results: Estimated desaturase activities and certain FAs were associated with anthropometric, clinical and biochemical indicators of cardiometabolic risk: D9D, D6D, 16:1n-7 and 20:3n-6 were directly associated, while D5D and 18:0 were inversely associated. However, the associations with clinical and biochemical indicators were not independent of the associations with the level of adiposity, since they were lost after controlling for anthropometric indices. After controlling for multiple confounders (age, postmenopausal status, education, smoking, physical activity, dietary macronutrient intakes, use of supplements, alcohol consumption), the level of adiposity was the most significant predictor of desaturase activities and aforementioned FAs levels, and mediated their association with biochemical/clinical indicators. Vice versa, desaturase activities predicted the level of adiposity, but not other components of cardiometabolic risk (if the level of adiposity was accounted). While the associations of anthropometric indices with 16:1n-7, 20:3n-6, 18:0 and D9D and D6D activities were linear, the associations with D5D activity were the inverse U-shaped. The only adiposity-independent association of FAs profiles with the indicators of cardiometabolic risk was a positive association of 20:5n-3 with ALT/AST ratio, which requires further exploration.

Discussion: Additional studies are needed to explore the mechanisms of the observed associations.",
publisher = "Frontiers Media S.A.",
journal = "Frontiers in Nutrition",
title = "Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-diabetic Serbian women: the role of level of adiposity",
volume = "10",
doi = "10.3389/fnut.2023.1065578",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1345"
}

Šarac, I., Debeljak-Martačić, J., Takić, M., Stevanović, V., Milešević, J., Zeković, M., Popović, T. B., Jovanović, J.,& Kardum Vidović, N.. (2023). Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-diabetic Serbian women: the role of level of adiposity. in Frontiers in Nutrition
Frontiers Media S.A.., 10.
https://doi.org/10.3389/fnut.2023.1065578
https://hdl.handle.net/21.15107/rcub_rimi_1345

Šarac I, Debeljak-Martačić J, Takić M, Stevanović V, Milešević J, Zeković M, Popović TB, Jovanović J, Kardum Vidović N. Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-diabetic Serbian women: the role of level of adiposity. in Frontiers in Nutrition. 2023;10.
doi:10.3389/fnut.2023.1065578
https://hdl.handle.net/21.15107/rcub_rimi_1345 .

Šarac, Ivana, Debeljak-Martačić, Jasmina, Takić, Marija, Stevanović, Vuk, Milešević, Jelena, Zeković, Milica, Popović, Tamara B., Jovanović, Jovica, Kardum Vidović, Nevena, "Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-diabetic Serbian women: the role of level of adiposity" in Frontiers in Nutrition, 10 (2023),
https://doi.org/10.3389/fnut.2023.1065578 .,
https://hdl.handle.net/21.15107/rcub_rimi_1345 .

TY  - JOUR
AU  - Stevanović, Vuk
AU  - Pantović, Ana
AU  - Krga, Irena
AU  - Zeković, Milica
AU  - Šarac, Ivana
AU  - Glibetić, Marija
AU  - Vidović, Nevena Đ.
PY  - 2020
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1021
AB  - Long-distance running, especially in non-professional runners, can increase cardiac arrest risk by enhancing platelet activation and aggregation. Polyphenols can exert cardioprotective effects by positively influencing platelet function. This study aimed to examine the acute effects of polyphenol-rich aronia juice consumption, before simulation of a half-marathon race, on platelet activation and aggregation with leukocytes in recreational runners. In this acute crossover study,10 healthy male runners (age 30.8 +/- 2.3 years) consumed breakfast with 200 mL, of aronia juice or 200 mL of placebo. They warmed-up and ran a simulated half-marathon race (21.1 km). Blood was collected at baseline, and at 15 min, 1 h, and 24 h after the run. All variables were analyzed with 4 (time) x 2 (group)ANOVA with repeated measures on both factors. Results revealed a significant effect of group on platelet activation parameters: P-selectin and CPIIb-IIIa expressions significantly decreased in the aronia group compared with the placebo group (F-[1.(9]) = 10.282, p = 0.011 and F-[1.9] = 7.860, p = 0.021, respectively). The effect of rime was significant on both platelet aggregation markers: platelet-monocyte and platelet-neutrophil aggregates were significantly lower after the race (F-[(3).7] = 4.227, p = 0.014 and F-[3.7] = 70.065, p = 0.000, respectively), with changes more pronounced in the later. All effects remained when platelets were exposed to an agonist. These results suggest that aronia consumption could counteract the half-marathon race-induced changes in platelet function. Novelty Aronia juice consumption significantly decreased the expression of platelet activation markers but did not affect platelet aggregation. The race itself did significantly reduce platelet-neutrophil aggregation. Aronia juice may serve as a supplement beverage for recreational runners to alleviate enhanced platelet reactivity caused by prolonged running.
PB  - Canadian Science Publishing, Ottawa
T2  - Applied Physiology Nutrition & Metabolism
T1  - Aronia juice consumption prior to half-marathon race can acutely affect platelet activation in recreational runners
EP  - 400
IS  - 4
SP  - 393
VL  - 45
DO  - 10.1139/apnm-2019-0267
ER  - 

@article{
author = "Stevanović, Vuk and Pantović, Ana and Krga, Irena and Zeković, Milica and Šarac, Ivana and Glibetić, Marija and Vidović, Nevena Đ.",
year = "2020",
abstract = "Long-distance running, especially in non-professional runners, can increase cardiac arrest risk by enhancing platelet activation and aggregation. Polyphenols can exert cardioprotective effects by positively influencing platelet function. This study aimed to examine the acute effects of polyphenol-rich aronia juice consumption, before simulation of a half-marathon race, on platelet activation and aggregation with leukocytes in recreational runners. In this acute crossover study,10 healthy male runners (age 30.8 +/- 2.3 years) consumed breakfast with 200 mL, of aronia juice or 200 mL of placebo. They warmed-up and ran a simulated half-marathon race (21.1 km). Blood was collected at baseline, and at 15 min, 1 h, and 24 h after the run. All variables were analyzed with 4 (time) x 2 (group)ANOVA with repeated measures on both factors. Results revealed a significant effect of group on platelet activation parameters: P-selectin and CPIIb-IIIa expressions significantly decreased in the aronia group compared with the placebo group (F-[1.(9]) = 10.282, p = 0.011 and F-[1.9] = 7.860, p = 0.021, respectively). The effect of rime was significant on both platelet aggregation markers: platelet-monocyte and platelet-neutrophil aggregates were significantly lower after the race (F-[(3).7] = 4.227, p = 0.014 and F-[3.7] = 70.065, p = 0.000, respectively), with changes more pronounced in the later. All effects remained when platelets were exposed to an agonist. These results suggest that aronia consumption could counteract the half-marathon race-induced changes in platelet function. Novelty Aronia juice consumption significantly decreased the expression of platelet activation markers but did not affect platelet aggregation. The race itself did significantly reduce platelet-neutrophil aggregation. Aronia juice may serve as a supplement beverage for recreational runners to alleviate enhanced platelet reactivity caused by prolonged running.",
publisher = "Canadian Science Publishing, Ottawa",
journal = "Applied Physiology Nutrition & Metabolism",
title = "Aronia juice consumption prior to half-marathon race can acutely affect platelet activation in recreational runners",
pages = "400-393",
number = "4",
volume = "45",
doi = "10.1139/apnm-2019-0267"
}

Stevanović, V., Pantović, A., Krga, I., Zeković, M., Šarac, I., Glibetić, M.,& Vidović, N. Đ.. (2020). Aronia juice consumption prior to half-marathon race can acutely affect platelet activation in recreational runners. in Applied Physiology Nutrition & Metabolism
Canadian Science Publishing, Ottawa., 45(4), 393-400.
https://doi.org/10.1139/apnm-2019-0267

Stevanović V, Pantović A, Krga I, Zeković M, Šarac I, Glibetić M, Vidović NĐ. Aronia juice consumption prior to half-marathon race can acutely affect platelet activation in recreational runners. in Applied Physiology Nutrition & Metabolism. 2020;45(4):393-400.
doi:10.1139/apnm-2019-0267 .

Stevanović, Vuk, Pantović, Ana, Krga, Irena, Zeković, Milica, Šarac, Ivana, Glibetić, Marija, Vidović, Nevena Đ., "Aronia juice consumption prior to half-marathon race can acutely affect platelet activation in recreational runners" in Applied Physiology Nutrition & Metabolism, 45, no. 4 (2020):393-400,
https://doi.org/10.1139/apnm-2019-0267 . .

TY  - JOUR
AU  - Stevanović, Vuk
AU  - Jelić, Milan
AU  - Milanović, Slađan
AU  - Filipović, Saša
AU  - Mikić, Mladen J.
AU  - Stojanović, Marko D. M.
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/918
AB  - The purpose of this study was to examine the acute effects of static stretching (SS) and dynamic stretching (DS), alone and in combination with specific basketball warm-up (SBWU), on the neuromuscular excitability and vertical jump height in basketball players. Twelve healthy young male basketball players participated in the study (18 +/- 0.42 years; 17.4 - 18.6 age range; 188 +/- 9 cm; 76.5 +/- 9 kg). All participants completed two different stretching treatments (static and dynamic), performed on different days at least seven days apart, in the same period of training microcycle, in a counterbalanced order. Each session consisted of a self-paced jogging warm-up, followed by a 10-minute testing period (T0), which involved eliciting H reflex and M waves, followed by three trials of a vertical jump test. Participants then performed one of the treatment protocols. After another test (T1), participants conducted 8-minute specific basketball warm-up and then one more test (T2). Combined 3 (time) x 2 (stretching protocol) analysis of variance with repeated measures on both factors revealed that SS significantly decreased spinal excitability (H/M ratio) (p = 0.015, d = -0.38, percentage of change = -20.55%) and vertical jump height (p = 0.007, d = -1.91, percentage of change = -2.6%), but after SBWU, vertical jump height increased (p = 0.006, d = 1.13, percentage of change = 3.01%), while H/M ratio continued decreasing (p = 0.019, d = -0.45, percentage of change = -30.23%). Acute effects of DS, alone and in combination with SBWU were not significant. It seems that SBWU attenuates negative acute effects of SS on vertical jump performance in young basketball players, while DS appears to cause no significant acute effect for this population.
PB  - Journal Sports Science & Medicine, Bursa
T2  - Journal of Sports Science & Medicine
T1  - Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players
EP  - 289
IS  - 2
SP  - 282
VL  - 18
UR  - https://hdl.handle.net/21.15107/rcub_rimi_918
ER  - 

@article{
author = "Stevanović, Vuk and Jelić, Milan and Milanović, Slađan and Filipović, Saša and Mikić, Mladen J. and Stojanović, Marko D. M.",
year = "2019",
abstract = "The purpose of this study was to examine the acute effects of static stretching (SS) and dynamic stretching (DS), alone and in combination with specific basketball warm-up (SBWU), on the neuromuscular excitability and vertical jump height in basketball players. Twelve healthy young male basketball players participated in the study (18 +/- 0.42 years; 17.4 - 18.6 age range; 188 +/- 9 cm; 76.5 +/- 9 kg). All participants completed two different stretching treatments (static and dynamic), performed on different days at least seven days apart, in the same period of training microcycle, in a counterbalanced order. Each session consisted of a self-paced jogging warm-up, followed by a 10-minute testing period (T0), which involved eliciting H reflex and M waves, followed by three trials of a vertical jump test. Participants then performed one of the treatment protocols. After another test (T1), participants conducted 8-minute specific basketball warm-up and then one more test (T2). Combined 3 (time) x 2 (stretching protocol) analysis of variance with repeated measures on both factors revealed that SS significantly decreased spinal excitability (H/M ratio) (p = 0.015, d = -0.38, percentage of change = -20.55%) and vertical jump height (p = 0.007, d = -1.91, percentage of change = -2.6%), but after SBWU, vertical jump height increased (p = 0.006, d = 1.13, percentage of change = 3.01%), while H/M ratio continued decreasing (p = 0.019, d = -0.45, percentage of change = -30.23%). Acute effects of DS, alone and in combination with SBWU were not significant. It seems that SBWU attenuates negative acute effects of SS on vertical jump performance in young basketball players, while DS appears to cause no significant acute effect for this population.",
publisher = "Journal Sports Science & Medicine, Bursa",
journal = "Journal of Sports Science & Medicine",
title = "Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players",
pages = "289-282",
number = "2",
volume = "18",
url = "https://hdl.handle.net/21.15107/rcub_rimi_918"
}

Stevanović, V., Jelić, M., Milanović, S., Filipović, S., Mikić, M. J.,& Stojanović, M. D. M.. (2019). Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players. in Journal of Sports Science & Medicine
Journal Sports Science & Medicine, Bursa., 18(2), 282-289.
https://hdl.handle.net/21.15107/rcub_rimi_918

Stevanović V, Jelić M, Milanović S, Filipović S, Mikić MJ, Stojanović MDM. Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players. in Journal of Sports Science & Medicine. 2019;18(2):282-289.
https://hdl.handle.net/21.15107/rcub_rimi_918 .

Stevanović, Vuk, Jelić, Milan, Milanović, Slađan, Filipović, Saša, Mikić, Mladen J., Stojanović, Marko D. M., "Sport-Specific Warm-Up Attenuates Static Stretching-Induced Negative Effects on Vertical Jump But Not Neuromuscular Excitability in Basketball Players" in Journal of Sports Science & Medicine, 18, no. 2 (2019):282-289,
https://hdl.handle.net/21.15107/rcub_rimi_918 .

TY  - JOUR
AU  - Jelić, Milan
AU  - Filipović, Saša
AU  - Milanović, Slađan
AU  - Stevanović, Vuk
AU  - Konstantinović, Ljubica
PY  - 2017
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/822
AB  - Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation.
PB  - Elsevier Ireland Ltd, Clare
T2  - Clinical Neurophysiology
T1  - Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand
EP  - 822
IS  - 5
SP  - 814
VL  - 128
DO  - 10.1016/j.clinph.2017.02.020
ER  - 

@article{
author = "Jelić, Milan and Filipović, Saša and Milanović, Slađan and Stevanović, Vuk and Konstantinović, Ljubica",
year = "2017",
abstract = "Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Clinical Neurophysiology",
title = "Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand",
pages = "822-814",
number = "5",
volume = "128",
doi = "10.1016/j.clinph.2017.02.020"
}

Jelić, M., Filipović, S., Milanović, S., Stevanović, V.,& Konstantinović, L.. (2017). Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand. in Clinical Neurophysiology
Elsevier Ireland Ltd, Clare., 128(5), 814-822.
https://doi.org/10.1016/j.clinph.2017.02.020

Jelić M, Filipović S, Milanović S, Stevanović V, Konstantinović L. Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand. in Clinical Neurophysiology. 2017;128(5):814-822.
doi:10.1016/j.clinph.2017.02.020 .

Jelić, Milan, Filipović, Saša, Milanović, Slađan, Stevanović, Vuk, Konstantinović, Ljubica, "Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand" in Clinical Neurophysiology, 128, no. 5 (2017):814-822,
https://doi.org/10.1016/j.clinph.2017.02.020 . .

TY  - THES
AU  - Stevanović, Vuk
PY  - 2016
UR  - https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146365578612040.pdf?controlNumber=(BISIS)1
UR  - http://nardus.mpn.gov.rs/handle/123456789/11341
UR  - https://www.cris.uns.ac.rs/record.jsf?recordId=101038&source=NaRDuS&language=sr
UR  - https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije146365580092987.pdf?controlNumber=(BI
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1106
AB  - Objective: The aim of this study was to determine the difference of acute effects of static stretching (SS) and dynamic stretching (DS), in combination with specific basketball warm-up (SBWU), on flexibility, explosive leg strength, speed, agility and neuromuscular adaptation of basketball players U18. Methods: This study consisted of two separated experiments, first in field conditions, and second conducted in laboratory. Both had „cross-over“ design. Forty-six basketball players (age: 17±0,83 years) participated in field experiment, while twelve participated in laboratory experiment (age 17,7±0,49 years). In field experiment, four motor abilities were tested. Seat and rech test was used for the evaluation of flexibility, explosive leg strength was evaluated by vertical jump from contact plate, speed by 20m run, and T test was used for agility testing. In laboratory experiment, the excitability of α-motoneuron was taken for the evaluation of neuromuscular adaptation. It is presented as a ratio of the maximal amplitudes of Hoffman (H) reflex and M wave (H/M). For their determining we used Medelec ST-10 stimulator (Medelec, Old Woking, UK). Surface electromyographic (EMG) electrodes were placed over the m.gastrocnemius medialis, and Achilles tendon, in a „belly-tendon“ montage. In both experiments, SS protocol and DS protocol, in the combination with SBWU, were used as a treatment. Measures were taken in 3 time points: before the stretching, immediately after stretching (and before SBWU) and immediately after the SBWU. Results: Results of this study showed that there are certain differences in acute effects of combination of protocols SS+SBWU and DS+SBWU. Combination of protocols SS+SBWU had more positive influence on explosive leg strength and agility of U18 basketball players. The effects of both protocols were almost the same on flexibility, and there was no noticeable difference in effects on speed, although before SBWU there was significant negative of SS. Immediately after the stretching there was significant difference in H/M ratio, it was significantly lower after the SS, but after the application of SBWU, differences disappeared.   Conlcusion: Regarding the effects of SS+SBWU and DS+SBWU protocols on motor abilities and neuromuscular adaptation of U18 basketball players, it could be concluded that the use of SS+SBWU is more preferrable in everyday practice and competition.
AB  - Cilj rada: Cilj istraživanja je da se utvrdi razlika u akutnim efektima statičkog (SI) i dinamičkog istezanja (DI), u kombinaciji sa specifičnim košarkaškim zagrevanjem (SKZ), na fleksibilnost, eksplozivnu snagu nogu, brzinu, agilnost i neuromišićnu adaptaciju košarkaša juniorskog uzrasta. Metode: Istraživanje u okviru ove doktorske teze su činila dva odvojena eksperimenta, jedan sproveden u terenskim uslovima, i drugi sproveden u laboratorijskim. Oba su bila „cross-over“ dizajna. U terenskom eksperimentu je učestvovalo 46 košarkaša (uzrasta 17±0,83 godina), dok je u laboratorijskom učestvovalo 12 (uzrasta 17,7±0,49 godina). U terenskom eksperimentu su testirane četiri motoričke sposobnosti. Za procenu fleksibilnosti korišćen je test dosezanja u sedećem pretklonu, eksplozivna snaga nogu je procenjivana uz pomoć vertikalnog skoka sa kontaktne ploče, brzina trčanjem na 20 metara, dok je T test korišćen za procenu agilnosti. U laboratorijskom eksperimentu je kao mera neurofiziološke adaptacije korišćena promena ekscitabilnosti α-motoneurona, koja je predstavljena kao odnos Hofmanovog (H) refleksa i M talasa (H/M). Za njihovo određivanje se koristio Medelec ST-10 stimulator (Medelec, Old Woking, UK). Površinske elektromiografske elektrode su bile postavljene na unutrašnjoj glavi m.gastrocnemius-a odskočne noge, primenom tzv. „belly-tendon“ montaže. Kao tretmani, u oba eksperimenta su korišćeni protokol statičkog i protokol dinamičkog istezanja, uz kombinaciju sa specifičnim košarkaškim zagrevanjem. Merenja su se u oba eksperimenta izvodila u 3 vremenske tačke i to pre protokola istezanja, odmah nakon protokola istezanja (a pre specifičnog košarkaškog zagrevanja) i odmah nakon specifičnog košarkaškog zagrevanja. Rezultati: Rezultati istraživanja pokazuju da postoje određene razlike akutnih efekata kombinacija protokola SI+SKZ i DI+SKZ. Kombinacija protokola SI+SKZ je povoljnije uticala na eksplozivnu snagu nogu i na agilnost košarkaša juniorskog uzrasta. Efekti obe kombinacije protokola su bili gotovo identični na fleksibilnost, a razlika je izostala i u efektima na brzinu, iako je pre SKZ bio uočljiv negativan efekat SI. Odnos H/M se značajno razlikovao odmah nakon istezanja, kada je SI značajno oborilo odnos, ali su se te razlike izgubile nakon primene SKZ. Zaključak: Posmatrajući efekte kombinacije protokola SI+SKZ i DI+SKZ na motoričke sposobnosti i neuromišićnu adaptaciju košarkaša juniorskog uzrasta, može se zaključiti da je primena SI+SKZ preporučljivija u svakodnevnom treningu i takmičenju.
PB  - Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja
T1  - Acute Effects of Different Types of Warm-up and Stretching on Motor Abilities and Neuromuscular Adaptation of Basketball Players
T1  - Akutni efekti različitih sadržaja uvodno-pripremnog dela treninga na motoričke sposobnosti i neuromišićnu adaptaciju košarkaša
UR  - https://hdl.handle.net/21.15107/rcub_nardus_11341
ER  - 

@phdthesis{
author = "Stevanović, Vuk",
year = "2016",
abstract = "Objective: The aim of this study was to determine the difference of acute effects of static stretching (SS) and dynamic stretching (DS), in combination with specific basketball warm-up (SBWU), on flexibility, explosive leg strength, speed, agility and neuromuscular adaptation of basketball players U18. Methods: This study consisted of two separated experiments, first in field conditions, and second conducted in laboratory. Both had „cross-over“ design. Forty-six basketball players (age: 17±0,83 years) participated in field experiment, while twelve participated in laboratory experiment (age 17,7±0,49 years). In field experiment, four motor abilities were tested. Seat and rech test was used for the evaluation of flexibility, explosive leg strength was evaluated by vertical jump from contact plate, speed by 20m run, and T test was used for agility testing. In laboratory experiment, the excitability of α-motoneuron was taken for the evaluation of neuromuscular adaptation. It is presented as a ratio of the maximal amplitudes of Hoffman (H) reflex and M wave (H/M). For their determining we used Medelec ST-10 stimulator (Medelec, Old Woking, UK). Surface electromyographic (EMG) electrodes were placed over the m.gastrocnemius medialis, and Achilles tendon, in a „belly-tendon“ montage. In both experiments, SS protocol and DS protocol, in the combination with SBWU, were used as a treatment. Measures were taken in 3 time points: before the stretching, immediately after stretching (and before SBWU) and immediately after the SBWU. Results: Results of this study showed that there are certain differences in acute effects of combination of protocols SS+SBWU and DS+SBWU. Combination of protocols SS+SBWU had more positive influence on explosive leg strength and agility of U18 basketball players. The effects of both protocols were almost the same on flexibility, and there was no noticeable difference in effects on speed, although before SBWU there was significant negative of SS. Immediately after the stretching there was significant difference in H/M ratio, it was significantly lower after the SS, but after the application of SBWU, differences disappeared.   Conlcusion: Regarding the effects of SS+SBWU and DS+SBWU protocols on motor abilities and neuromuscular adaptation of U18 basketball players, it could be concluded that the use of SS+SBWU is more preferrable in everyday practice and competition., Cilj rada: Cilj istraživanja je da se utvrdi razlika u akutnim efektima statičkog (SI) i dinamičkog istezanja (DI), u kombinaciji sa specifičnim košarkaškim zagrevanjem (SKZ), na fleksibilnost, eksplozivnu snagu nogu, brzinu, agilnost i neuromišićnu adaptaciju košarkaša juniorskog uzrasta. Metode: Istraživanje u okviru ove doktorske teze su činila dva odvojena eksperimenta, jedan sproveden u terenskim uslovima, i drugi sproveden u laboratorijskim. Oba su bila „cross-over“ dizajna. U terenskom eksperimentu je učestvovalo 46 košarkaša (uzrasta 17±0,83 godina), dok je u laboratorijskom učestvovalo 12 (uzrasta 17,7±0,49 godina). U terenskom eksperimentu su testirane četiri motoričke sposobnosti. Za procenu fleksibilnosti korišćen je test dosezanja u sedećem pretklonu, eksplozivna snaga nogu je procenjivana uz pomoć vertikalnog skoka sa kontaktne ploče, brzina trčanjem na 20 metara, dok je T test korišćen za procenu agilnosti. U laboratorijskom eksperimentu je kao mera neurofiziološke adaptacije korišćena promena ekscitabilnosti α-motoneurona, koja je predstavljena kao odnos Hofmanovog (H) refleksa i M talasa (H/M). Za njihovo određivanje se koristio Medelec ST-10 stimulator (Medelec, Old Woking, UK). Površinske elektromiografske elektrode su bile postavljene na unutrašnjoj glavi m.gastrocnemius-a odskočne noge, primenom tzv. „belly-tendon“ montaže. Kao tretmani, u oba eksperimenta su korišćeni protokol statičkog i protokol dinamičkog istezanja, uz kombinaciju sa specifičnim košarkaškim zagrevanjem. Merenja su se u oba eksperimenta izvodila u 3 vremenske tačke i to pre protokola istezanja, odmah nakon protokola istezanja (a pre specifičnog košarkaškog zagrevanja) i odmah nakon specifičnog košarkaškog zagrevanja. Rezultati: Rezultati istraživanja pokazuju da postoje određene razlike akutnih efekata kombinacija protokola SI+SKZ i DI+SKZ. Kombinacija protokola SI+SKZ je povoljnije uticala na eksplozivnu snagu nogu i na agilnost košarkaša juniorskog uzrasta. Efekti obe kombinacije protokola su bili gotovo identični na fleksibilnost, a razlika je izostala i u efektima na brzinu, iako je pre SKZ bio uočljiv negativan efekat SI. Odnos H/M se značajno razlikovao odmah nakon istezanja, kada je SI značajno oborilo odnos, ali su se te razlike izgubile nakon primene SKZ. Zaključak: Posmatrajući efekte kombinacije protokola SI+SKZ i DI+SKZ na motoričke sposobnosti i neuromišićnu adaptaciju košarkaša juniorskog uzrasta, može se zaključiti da je primena SI+SKZ preporučljivija u svakodnevnom treningu i takmičenju.",
publisher = "Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja",
title = "Acute Effects of Different Types of Warm-up and Stretching on Motor Abilities and Neuromuscular Adaptation of Basketball Players, Akutni efekti različitih sadržaja uvodno-pripremnog dela treninga na motoričke sposobnosti i neuromišićnu adaptaciju košarkaša",
url = "https://hdl.handle.net/21.15107/rcub_nardus_11341"
}

Stevanović, V.. (2016). Acute Effects of Different Types of Warm-up and Stretching on Motor Abilities and Neuromuscular Adaptation of Basketball Players. 
Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja..
https://hdl.handle.net/21.15107/rcub_nardus_11341

Stevanović V. Acute Effects of Different Types of Warm-up and Stretching on Motor Abilities and Neuromuscular Adaptation of Basketball Players. 2016;.
https://hdl.handle.net/21.15107/rcub_nardus_11341 .

Stevanović, Vuk, "Acute Effects of Different Types of Warm-up and Stretching on Motor Abilities and Neuromuscular Adaptation of Basketball Players" (2016),
https://hdl.handle.net/21.15107/rcub_nardus_11341 .

TY  - JOUR
AU  - Konstantinović, Ljubica
AU  - Jelić, Milan
AU  - Jeremić, Aleksandra
AU  - Stevanović, Vuk
AU  - Milanović, Slađan
AU  - Filipović, Saša
PY  - 2013
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/477
AB  - Background and Objective: Near-infrared low-level laser (NIR-LLL) irradiation penetrates scalp and skull and can reach superficial layers of the cerebral cortex. It was shown to improve the outcome of acute stroke in both animal and human studies. In this study we evaluated whether transcranial laser stimulation (TLS) with NIR-LLL can modulate the excitability of the motor cortex (M1) as measured by transcranial magnetic stimulation (TMS). Methods: TLS was applied for 5 minutes over the representation of the right first dorsal interosseal muscle (FDI) in left primary motor cortex (M1), in 14 healthy subjects. Motor evoked potentials (MEPs) from the FDI, elicited by single-pulse TMS, were measured at baseline and up to 30 minutes after the TLS. Results: The average MEP size was significantly reduced during the first 20 minutes following the TLS. The pattern was present in 10(71.5%) of the participants. The MEP size reduction correlated negatively with the motor threshold at rest. Conclusions: TLS with NIR-LLL induced transitory reduction of the excitability of the stimulated cortex. These findings give further insights into the mechanisms of TLS effects in the human cerebral cortex, paving the way for potential applications of TLS in treatment of stroke and in other clinical settings. Lasers Surg. Med. 45:648-653, 2013.
PB  - Wiley-Blackwell, Hoboken
T2  - Lasers in Surgery & Medicine
T1  - Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability
EP  - 653
IS  - 10
SP  - 648
VL  - 45
DO  - 10.1002/lsm.22190
ER  - 

@article{
author = "Konstantinović, Ljubica and Jelić, Milan and Jeremić, Aleksandra and Stevanović, Vuk and Milanović, Slađan and Filipović, Saša",
year = "2013",
abstract = "Background and Objective: Near-infrared low-level laser (NIR-LLL) irradiation penetrates scalp and skull and can reach superficial layers of the cerebral cortex. It was shown to improve the outcome of acute stroke in both animal and human studies. In this study we evaluated whether transcranial laser stimulation (TLS) with NIR-LLL can modulate the excitability of the motor cortex (M1) as measured by transcranial magnetic stimulation (TMS). Methods: TLS was applied for 5 minutes over the representation of the right first dorsal interosseal muscle (FDI) in left primary motor cortex (M1), in 14 healthy subjects. Motor evoked potentials (MEPs) from the FDI, elicited by single-pulse TMS, were measured at baseline and up to 30 minutes after the TLS. Results: The average MEP size was significantly reduced during the first 20 minutes following the TLS. The pattern was present in 10(71.5%) of the participants. The MEP size reduction correlated negatively with the motor threshold at rest. Conclusions: TLS with NIR-LLL induced transitory reduction of the excitability of the stimulated cortex. These findings give further insights into the mechanisms of TLS effects in the human cerebral cortex, paving the way for potential applications of TLS in treatment of stroke and in other clinical settings. Lasers Surg. Med. 45:648-653, 2013.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Lasers in Surgery & Medicine",
title = "Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability",
pages = "653-648",
number = "10",
volume = "45",
doi = "10.1002/lsm.22190"
}

Konstantinović, L., Jelić, M., Jeremić, A., Stevanović, V., Milanović, S.,& Filipović, S.. (2013). Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability. in Lasers in Surgery & Medicine
Wiley-Blackwell, Hoboken., 45(10), 648-653.
https://doi.org/10.1002/lsm.22190

Konstantinović L, Jelić M, Jeremić A, Stevanović V, Milanović S, Filipović S. Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability. in Lasers in Surgery & Medicine. 2013;45(10):648-653.
doi:10.1002/lsm.22190 .

Konstantinović, Ljubica, Jelić, Milan, Jeremić, Aleksandra, Stevanović, Vuk, Milanović, Slađan, Filipović, Saša, "Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability" in Lasers in Surgery & Medicine, 45, no. 10 (2013):648-653,
https://doi.org/10.1002/lsm.22190 . .

TY  - JOUR
AU  - Jelić, Milan
AU  - Stevanović, Vuk
AU  - Milanović, Slađan
AU  - Ljubisavljević, Miloš
AU  - Filipović, Saša
PY  - 2013
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/498
AB  - Objective: Motor learning is the core cognitive function in neurorehabilitation and in various other skill-training activities (e. g. sport, music). Therefore, there is an increasing interest in the use of transcranial magnetic stimulation (TMS) methods for its enhancement. However, although usually assumed, a potential placebo effect of TMS methods on motor learning has never been systematically investigated. Methods: Improvement of performance on the Purdue Pegboard Task over three test-blocks (T0, T1, and T2), separated by  gt 20 min, was used to evaluate motor learning. In Experiment-1, two groups of 10 participants each were compared: one group immediately before T1 received a sham intermittent theta burst stimulation procedure (P-iTBS group), while another did not have any intervention at all (control - CON group). In Experiment-2, a third group of participants (six subjects) who received sham high-frequency repetitive TMS procedure before T1 (P-rTMS group) was compared with P-iTBS group. Results: All three groups showed significant learning over time, but without any difference between them, either in Experiment-1 between P-iTBS and CON, or in Experiment-2 between P-rTMS and P-iTBS. Conclusion: The results suggest lack of any placebo effect of TMS on motor learning. Significance: The results may help in designing further TMS-motor learning studies and in interpreting their results.
PB  - Elsevier Ireland Ltd, Clare
T2  - Clinical Neurophysiology
T1  - Transcranial magnetic stimulation has no placebo effect on motor learning
EP  - 1651
IS  - 8
SP  - 1646
VL  - 124
DO  - 10.1016/j.clinph.2013.02.024
ER  - 

@article{
author = "Jelić, Milan and Stevanović, Vuk and Milanović, Slađan and Ljubisavljević, Miloš and Filipović, Saša",
year = "2013",
abstract = "Objective: Motor learning is the core cognitive function in neurorehabilitation and in various other skill-training activities (e. g. sport, music). Therefore, there is an increasing interest in the use of transcranial magnetic stimulation (TMS) methods for its enhancement. However, although usually assumed, a potential placebo effect of TMS methods on motor learning has never been systematically investigated. Methods: Improvement of performance on the Purdue Pegboard Task over three test-blocks (T0, T1, and T2), separated by  gt 20 min, was used to evaluate motor learning. In Experiment-1, two groups of 10 participants each were compared: one group immediately before T1 received a sham intermittent theta burst stimulation procedure (P-iTBS group), while another did not have any intervention at all (control - CON group). In Experiment-2, a third group of participants (six subjects) who received sham high-frequency repetitive TMS procedure before T1 (P-rTMS group) was compared with P-iTBS group. Results: All three groups showed significant learning over time, but without any difference between them, either in Experiment-1 between P-iTBS and CON, or in Experiment-2 between P-rTMS and P-iTBS. Conclusion: The results suggest lack of any placebo effect of TMS on motor learning. Significance: The results may help in designing further TMS-motor learning studies and in interpreting their results.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Clinical Neurophysiology",
title = "Transcranial magnetic stimulation has no placebo effect on motor learning",
pages = "1651-1646",
number = "8",
volume = "124",
doi = "10.1016/j.clinph.2013.02.024"
}

Jelić, M., Stevanović, V., Milanović, S., Ljubisavljević, M.,& Filipović, S.. (2013). Transcranial magnetic stimulation has no placebo effect on motor learning. in Clinical Neurophysiology
Elsevier Ireland Ltd, Clare., 124(8), 1646-1651.
https://doi.org/10.1016/j.clinph.2013.02.024

Jelić M, Stevanović V, Milanović S, Ljubisavljević M, Filipović S. Transcranial magnetic stimulation has no placebo effect on motor learning. in Clinical Neurophysiology. 2013;124(8):1646-1651.
doi:10.1016/j.clinph.2013.02.024 .

Jelić, Milan, Stevanović, Vuk, Milanović, Slađan, Ljubisavljević, Miloš, Filipović, Saša, "Transcranial magnetic stimulation has no placebo effect on motor learning" in Clinical Neurophysiology, 124, no. 8 (2013):1646-1651,
https://doi.org/10.1016/j.clinph.2013.02.024 . .