Konstantinović, Ljubica

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orcid::0000-0001-5906-1594
  • Konstantinović, Ljubica (7)
Projects

Author's Bibliography

Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems

Filipović, Saša; Knežević, T.; Rodić, S.; Milanović, Slađan; Drulović, Jelena; Konstantinović, Ljubica

(Wiley, Hoboken, 2020)

TY  - CONF
AU  - Filipović, Saša
AU  - Knežević, T.
AU  - Rodić, S.
AU  - Milanović, Slađan
AU  - Drulović, Jelena
AU  - Konstantinović, Ljubica
PY  - 2020
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1065
PB  - Wiley, Hoboken
C3  - European Journal of Neurology
T1  - Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems
EP  - 1016
SP  - 1016
VL  - 27
UR  - https://hdl.handle.net/21.15107/rcub_rimi_1065
ER  - 
@conference{
author = "Filipović, Saša and Knežević, T. and Rodić, S. and Milanović, Slađan and Drulović, Jelena and Konstantinović, Ljubica",
year = "2020",
publisher = "Wiley, Hoboken",
journal = "European Journal of Neurology",
title = "Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems",
pages = "1016-1016",
volume = "27",
url = "https://hdl.handle.net/21.15107/rcub_rimi_1065"
}
Filipović, S., Knežević, T., Rodić, S., Milanović, S., Drulović, J.,& Konstantinović, L.. (2020). Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems. in European Journal of Neurology
Wiley, Hoboken., 27, 1016-1016.
https://hdl.handle.net/21.15107/rcub_rimi_1065
Filipović S, Knežević T, Rodić S, Milanović S, Drulović J, Konstantinović L. Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems. in European Journal of Neurology. 2020;27:1016-1016.
https://hdl.handle.net/21.15107/rcub_rimi_1065 .
Filipović, Saša, Knežević, T., Rodić, S., Milanović, Slađan, Drulović, Jelena, Konstantinović, Ljubica, "Reliability of H-reflex as a paraclinical measure in neurorehabilitation of progressive multiple sclerosis patients with leg spasticity and gait problems" in European Journal of Neurology, 27 (2020):1016-1016,
https://hdl.handle.net/21.15107/rcub_rimi_1065 .

Effects of near-infrared low-level laser stimulation on neuronal excitability

Konstantinović, Ljubica; Filipović, Saša

(2019)

TY  - CHAP
AU  - Konstantinović, Ljubica
AU  - Filipović, Saša
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/972
AB  - Effects of near-infrared low-level laser (NIR LLL) on brain excitability have been seldom investigated. A few studies carried out so far showed that following several minutes of transcranial NIR LLL illumination, the output of the primary motor cortex area in humans, measured by transcranial magnetic stimulation (TMS), is inhibited for at least half an hour. The effect seems to be dose dependent. Given that NIR LLL is known to boost metabolic activity in the illuminated neurons, the results may suggest that this allows for more efficient functioning of the cell membrane potential maintenance mechanisms which are then able to resist more effectively external perturbations (such as TMS). Alternatively, it may be that, due to the morphological complexity of the cerebral cortex coupled with the size of the area illuminated by a laser beam, transcranial LLL induces activation in a large population of the cortical cells of various functional features. Because of their abundance in the most superficial cortical layers, inhibitory interneurons may be the principal recipients of the NIR LLL effects thus causing an inhibition of the output from more deeply-seated, large pyramidal cells. Further investigations are needed to better understand these effects.
T2  - Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology & Neuroscience
T1  - Effects of near-infrared low-level laser stimulation on neuronal excitability
EP  - 240
SP  - 233
DO  - 10.1016/B978-0-12-815305-5.00018-X
ER  - 
@inbook{
author = "Konstantinović, Ljubica and Filipović, Saša",
year = "2019",
abstract = "Effects of near-infrared low-level laser (NIR LLL) on brain excitability have been seldom investigated. A few studies carried out so far showed that following several minutes of transcranial NIR LLL illumination, the output of the primary motor cortex area in humans, measured by transcranial magnetic stimulation (TMS), is inhibited for at least half an hour. The effect seems to be dose dependent. Given that NIR LLL is known to boost metabolic activity in the illuminated neurons, the results may suggest that this allows for more efficient functioning of the cell membrane potential maintenance mechanisms which are then able to resist more effectively external perturbations (such as TMS). Alternatively, it may be that, due to the morphological complexity of the cerebral cortex coupled with the size of the area illuminated by a laser beam, transcranial LLL induces activation in a large population of the cortical cells of various functional features. Because of their abundance in the most superficial cortical layers, inhibitory interneurons may be the principal recipients of the NIR LLL effects thus causing an inhibition of the output from more deeply-seated, large pyramidal cells. Further investigations are needed to better understand these effects.",
journal = "Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology & Neuroscience",
booktitle = "Effects of near-infrared low-level laser stimulation on neuronal excitability",
pages = "240-233",
doi = "10.1016/B978-0-12-815305-5.00018-X"
}
Konstantinović, L.,& Filipović, S.. (2019). Effects of near-infrared low-level laser stimulation on neuronal excitability. in Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology & Neuroscience, 233-240.
https://doi.org/10.1016/B978-0-12-815305-5.00018-X
Konstantinović L, Filipović S. Effects of near-infrared low-level laser stimulation on neuronal excitability. in Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology & Neuroscience. 2019;:233-240.
doi:10.1016/B978-0-12-815305-5.00018-X .
Konstantinović, Ljubica, Filipović, Saša, "Effects of near-infrared low-level laser stimulation on neuronal excitability" in Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology & Neuroscience (2019):233-240,
https://doi.org/10.1016/B978-0-12-815305-5.00018-X . .
4
2

Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia

Vuksanović, Jasmina; Milovanović, Tanja; Konstantinović, Ljubica; Filipović, Saša

(Wiley, Hoboken, 2018)

TY  - JOUR
AU  - Vuksanović, Jasmina
AU  - Milovanović, Tanja
AU  - Konstantinović, Ljubica
AU  - Filipović, Saša
PY  - 2018
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/887
AB  - BackgroundConstraint-induced (language) aphasia therapy (CIAT), based on constraint usage of the language channel only, massed practice and shaping through therapeutic language games, has been suggested as a more efficient therapy approach than traditional aphasia therapies. AimsTo examine the comparative efficacy of CIAT and a traditional therapy approach on expressive language ability, with the intensity of therapy controlled and matched, in the treatment of post-stroke aphasia. Methods & ProceduresTwo successive 4-week blocks of intense (1 h, 5 days a week) of aphasia therapy programmes were delivered in a randomized within-subject crossover design: one therapy block consisted of stimulation aphasia therapy (SAT, a common traditional therapy approach), another of CIAT. Twenty consecutive patients, up to 1 year after stroke, were randomly assigned either to have SAT followed by CIAT (S1C2 group) or to have CIAT followed by SAT (C1S2 group). Measurements of naming (Boston Naming Test) and spontaneous sentence production (Cookie Theft Picture description task) were carried at the baseline, following the first therapy block, following the second therapy block and 4 weeks following the last therapy block. Outcomes & ResultsBoth groups of patients significantly improved in all variables of expressive language skills; the improvement was maintained 1 month post-treatment. However, patients who started with CIAT and continued with SAT (C1S2 group) tended to have higher final improvement than the patients who started with SAT and continued with CIAT (S1C2 group). This was particularly pronounced for naming. Moreover, when CIAT was the first therapy (the C1S2 group) the improvement achieved in naming following CIAT significantly exceeded the improvements achieved following SAT, not only in the same group (when SAT was the second) but also in the S1C2 group (when SAT was the first). In addition, the improvement in naming following CIAT in the C1S2 group exceeded the one in the S1C2 group, too. Similarly, the improvement in the total number of sentences produced following each therapy was quite clear and significant in the C1S2 group (when CIAT was the first), while in the S1C2 group it was much more modest and not significant. Conclusions & ImplicationsResults suggest that the maximization of quantity and frequency of language therapy have a significant impact on the improvement of expressive language ability. Moreover, if practised early in aphasia therapy, the constrained usage of the language modality, as practised in CIAT, confers an additional benefit to massed practice, particularly on naming ability.
PB  - Wiley, Hoboken
T2  - International Journal of Language & Communication Disorders
T1  - Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia
EP  - 835
IS  - 4
SP  - 825
VL  - 53
DO  - 10.1111/1460-6984.12390
ER  - 
@article{
author = "Vuksanović, Jasmina and Milovanović, Tanja and Konstantinović, Ljubica and Filipović, Saša",
year = "2018",
abstract = "BackgroundConstraint-induced (language) aphasia therapy (CIAT), based on constraint usage of the language channel only, massed practice and shaping through therapeutic language games, has been suggested as a more efficient therapy approach than traditional aphasia therapies. AimsTo examine the comparative efficacy of CIAT and a traditional therapy approach on expressive language ability, with the intensity of therapy controlled and matched, in the treatment of post-stroke aphasia. Methods & ProceduresTwo successive 4-week blocks of intense (1 h, 5 days a week) of aphasia therapy programmes were delivered in a randomized within-subject crossover design: one therapy block consisted of stimulation aphasia therapy (SAT, a common traditional therapy approach), another of CIAT. Twenty consecutive patients, up to 1 year after stroke, were randomly assigned either to have SAT followed by CIAT (S1C2 group) or to have CIAT followed by SAT (C1S2 group). Measurements of naming (Boston Naming Test) and spontaneous sentence production (Cookie Theft Picture description task) were carried at the baseline, following the first therapy block, following the second therapy block and 4 weeks following the last therapy block. Outcomes & ResultsBoth groups of patients significantly improved in all variables of expressive language skills; the improvement was maintained 1 month post-treatment. However, patients who started with CIAT and continued with SAT (C1S2 group) tended to have higher final improvement than the patients who started with SAT and continued with CIAT (S1C2 group). This was particularly pronounced for naming. Moreover, when CIAT was the first therapy (the C1S2 group) the improvement achieved in naming following CIAT significantly exceeded the improvements achieved following SAT, not only in the same group (when SAT was the second) but also in the S1C2 group (when SAT was the first). In addition, the improvement in naming following CIAT in the C1S2 group exceeded the one in the S1C2 group, too. Similarly, the improvement in the total number of sentences produced following each therapy was quite clear and significant in the C1S2 group (when CIAT was the first), while in the S1C2 group it was much more modest and not significant. Conclusions & ImplicationsResults suggest that the maximization of quantity and frequency of language therapy have a significant impact on the improvement of expressive language ability. Moreover, if practised early in aphasia therapy, the constrained usage of the language modality, as practised in CIAT, confers an additional benefit to massed practice, particularly on naming ability.",
publisher = "Wiley, Hoboken",
journal = "International Journal of Language & Communication Disorders",
title = "Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia",
pages = "835-825",
number = "4",
volume = "53",
doi = "10.1111/1460-6984.12390"
}
Vuksanović, J., Milovanović, T., Konstantinović, L.,& Filipović, S.. (2018). Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia. in International Journal of Language & Communication Disorders
Wiley, Hoboken., 53(4), 825-835.
https://doi.org/10.1111/1460-6984.12390
Vuksanović J, Milovanović T, Konstantinović L, Filipović S. Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia. in International Journal of Language & Communication Disorders. 2018;53(4):825-835.
doi:10.1111/1460-6984.12390 .
Vuksanović, Jasmina, Milovanović, Tanja, Konstantinović, Ljubica, Filipović, Saša, "Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia" in International Journal of Language & Communication Disorders, 53, no. 4 (2018):825-835,
https://doi.org/10.1111/1460-6984.12390 . .
2
8
5
7

Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand

Jelić, Milan; Filipović, Saša; Milanović, Slađan; Stevanović, Vuk; Konstantinović, Ljubica

(Elsevier Ireland Ltd, Clare, 2017)

TY  - JOUR
AU  - Jelić, Milan
AU  - Filipović, Saša
AU  - Milanović, Slađan
AU  - Stevanović, Vuk
AU  - Konstantinović, Ljubica
PY  - 2017
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/822
AB  - Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation.
PB  - Elsevier Ireland Ltd, Clare
T2  - Clinical Neurophysiology
T1  - Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand
EP  - 822
IS  - 5
SP  - 814
VL  - 128
DO  - 10.1016/j.clinph.2017.02.020
ER  - 
@article{
author = "Jelić, Milan and Filipović, Saša and Milanović, Slađan and Stevanović, Vuk and Konstantinović, Ljubica",
year = "2017",
abstract = "Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Clinical Neurophysiology",
title = "Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand",
pages = "822-814",
number = "5",
volume = "128",
doi = "10.1016/j.clinph.2017.02.020"
}
Jelić, M., Filipović, S., Milanović, S., Stevanović, V.,& Konstantinović, L.. (2017). Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand. in Clinical Neurophysiology
Elsevier Ireland Ltd, Clare., 128(5), 814-822.
https://doi.org/10.1016/j.clinph.2017.02.020
Jelić M, Filipović S, Milanović S, Stevanović V, Konstantinović L. Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand. in Clinical Neurophysiology. 2017;128(5):814-822.
doi:10.1016/j.clinph.2017.02.020 .
Jelić, Milan, Filipović, Saša, Milanović, Slađan, Stevanović, Vuk, Konstantinović, Ljubica, "Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand" in Clinical Neurophysiology, 128, no. 5 (2017):814-822,
https://doi.org/10.1016/j.clinph.2017.02.020 . .
4
2
1
1

Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following bilateral sequential theta burst magnetic stimulation

Vuksanović, Jasmina; Jelić, Milan; Milanović, Slađan; Kacar, Katarina; Konstantinović, Ljubica; Filipović, Saša

(Routledge Journals, Taylor & Francis Ltd, Abingdon, 2015)

TY  - JOUR
AU  - Vuksanović, Jasmina
AU  - Jelić, Milan
AU  - Milanović, Slađan
AU  - Kacar, Katarina
AU  - Konstantinović, Ljubica
AU  - Filipović, Saša
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/664
AB  - In chronic non-fluent aphasia patients, inhibition of the intact right hemisphere (RH), by transcranial magnetic stimulation (TMS) or similar methods, can induce improvement in language functions. The supposed mechanism behind this improvement is a release of preserved left hemisphere (LH) language networks from RH transcallosal inhibition. Direct stimulation of the damaged LH can sometimes bring similar results too. Therefore, we developed a novel treatment approach that combined direct LH (Broca's area (BA)) stimulation, by intermittent theta burst stimulation (TBS), with homologue RH area's inhibition, by continuous TBS. We present the results of application of 15 daily sessions of the described treatment approach in a right-handed patient with chronic post-stroke non-fluent aphasia. The intervention appeared to improve several language functions, but most notably propositional speech, semantic fluency, short-term verbal memory, and verbal learning. Bilateral TBS modulation of activation of the language-related areas of both hemispheres seems to be a feasible and promising way to induce recovery in chronic aphasic patients. Due to potentially cumulative physiological effects of bilateral stimulation, the improvements may be even greater than following unilateral interventions.
PB  - Routledge Journals, Taylor & Francis Ltd, Abingdon
T2  - Neurocase
T1  - Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following bilateral sequential theta burst magnetic stimulation
EP  - 250
IS  - 2
SP  - 244
VL  - 21
DO  - 10.1080/13554794.2014.890731
ER  - 
@article{
author = "Vuksanović, Jasmina and Jelić, Milan and Milanović, Slađan and Kacar, Katarina and Konstantinović, Ljubica and Filipović, Saša",
year = "2015",
abstract = "In chronic non-fluent aphasia patients, inhibition of the intact right hemisphere (RH), by transcranial magnetic stimulation (TMS) or similar methods, can induce improvement in language functions. The supposed mechanism behind this improvement is a release of preserved left hemisphere (LH) language networks from RH transcallosal inhibition. Direct stimulation of the damaged LH can sometimes bring similar results too. Therefore, we developed a novel treatment approach that combined direct LH (Broca's area (BA)) stimulation, by intermittent theta burst stimulation (TBS), with homologue RH area's inhibition, by continuous TBS. We present the results of application of 15 daily sessions of the described treatment approach in a right-handed patient with chronic post-stroke non-fluent aphasia. The intervention appeared to improve several language functions, but most notably propositional speech, semantic fluency, short-term verbal memory, and verbal learning. Bilateral TBS modulation of activation of the language-related areas of both hemispheres seems to be a feasible and promising way to induce recovery in chronic aphasic patients. Due to potentially cumulative physiological effects of bilateral stimulation, the improvements may be even greater than following unilateral interventions.",
publisher = "Routledge Journals, Taylor & Francis Ltd, Abingdon",
journal = "Neurocase",
title = "Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following bilateral sequential theta burst magnetic stimulation",
pages = "250-244",
number = "2",
volume = "21",
doi = "10.1080/13554794.2014.890731"
}
Vuksanović, J., Jelić, M., Milanović, S., Kacar, K., Konstantinović, L.,& Filipović, S.. (2015). Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following bilateral sequential theta burst magnetic stimulation. in Neurocase
Routledge Journals, Taylor & Francis Ltd, Abingdon., 21(2), 244-250.
https://doi.org/10.1080/13554794.2014.890731
Vuksanović J, Jelić M, Milanović S, Kacar K, Konstantinović L, Filipović S. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following bilateral sequential theta burst magnetic stimulation. in Neurocase. 2015;21(2):244-250.
doi:10.1080/13554794.2014.890731 .
Vuksanović, Jasmina, Jelić, Milan, Milanović, Slađan, Kacar, Katarina, Konstantinović, Ljubica, Filipović, Saša, "Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following bilateral sequential theta burst magnetic stimulation" in Neurocase, 21, no. 2 (2015):244-250,
https://doi.org/10.1080/13554794.2014.890731 . .
34
16
33

Language functions in two chronic non-fluent post-stroke aphasic patients following bilateral physiologically balanced non-invasive neuromodulation by theta burst magnetic stimulation

Živanović, M.; Vutksanović, J.; Filipović, Saša; Jelić, Milan; Jeremić, Aleksandra; Konstantinović, Ljubica

(Karger, Basel, 2014)

TY  - CONF
AU  - Živanović, M.
AU  - Vutksanović, J.
AU  - Filipović, Saša
AU  - Jelić, Milan
AU  - Jeremić, Aleksandra
AU  - Konstantinović, Ljubica
PY  - 2014
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/582
PB  - Karger, Basel
C3  - Cerebrovascular Diseases
T1  - Language functions in two chronic non-fluent post-stroke aphasic patients following bilateral physiologically balanced non-invasive neuromodulation by theta burst magnetic stimulation
EP  - 318
SP  - 318
VL  - 37
UR  - https://hdl.handle.net/21.15107/rcub_rimi_582
ER  - 
@conference{
author = "Živanović, M. and Vutksanović, J. and Filipović, Saša and Jelić, Milan and Jeremić, Aleksandra and Konstantinović, Ljubica",
year = "2014",
publisher = "Karger, Basel",
journal = "Cerebrovascular Diseases",
title = "Language functions in two chronic non-fluent post-stroke aphasic patients following bilateral physiologically balanced non-invasive neuromodulation by theta burst magnetic stimulation",
pages = "318-318",
volume = "37",
url = "https://hdl.handle.net/21.15107/rcub_rimi_582"
}
Živanović, M., Vutksanović, J., Filipović, S., Jelić, M., Jeremić, A.,& Konstantinović, L.. (2014). Language functions in two chronic non-fluent post-stroke aphasic patients following bilateral physiologically balanced non-invasive neuromodulation by theta burst magnetic stimulation. in Cerebrovascular Diseases
Karger, Basel., 37, 318-318.
https://hdl.handle.net/21.15107/rcub_rimi_582
Živanović M, Vutksanović J, Filipović S, Jelić M, Jeremić A, Konstantinović L. Language functions in two chronic non-fluent post-stroke aphasic patients following bilateral physiologically balanced non-invasive neuromodulation by theta burst magnetic stimulation. in Cerebrovascular Diseases. 2014;37:318-318.
https://hdl.handle.net/21.15107/rcub_rimi_582 .
Živanović, M., Vutksanović, J., Filipović, Saša, Jelić, Milan, Jeremić, Aleksandra, Konstantinović, Ljubica, "Language functions in two chronic non-fluent post-stroke aphasic patients following bilateral physiologically balanced non-invasive neuromodulation by theta burst magnetic stimulation" in Cerebrovascular Diseases, 37 (2014):318-318,
https://hdl.handle.net/21.15107/rcub_rimi_582 .

Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability

Konstantinović, Ljubica; Jelić, Milan; Jeremić, Aleksandra; Stevanović, Vuk; Milanović, Slađan; Filipović, Saša

(Wiley-Blackwell, Hoboken, 2013)

TY  - JOUR
AU  - Konstantinović, Ljubica
AU  - Jelić, Milan
AU  - Jeremić, Aleksandra
AU  - Stevanović, Vuk
AU  - Milanović, Slađan
AU  - Filipović, Saša
PY  - 2013
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/477
AB  - Background and Objective: Near-infrared low-level laser (NIR-LLL) irradiation penetrates scalp and skull and can reach superficial layers of the cerebral cortex. It was shown to improve the outcome of acute stroke in both animal and human studies. In this study we evaluated whether transcranial laser stimulation (TLS) with NIR-LLL can modulate the excitability of the motor cortex (M1) as measured by transcranial magnetic stimulation (TMS). Methods: TLS was applied for 5 minutes over the representation of the right first dorsal interosseal muscle (FDI) in left primary motor cortex (M1), in 14 healthy subjects. Motor evoked potentials (MEPs) from the FDI, elicited by single-pulse TMS, were measured at baseline and up to 30 minutes after the TLS. Results: The average MEP size was significantly reduced during the first 20 minutes following the TLS. The pattern was present in 10(71.5%) of the participants. The MEP size reduction correlated negatively with the motor threshold at rest. Conclusions: TLS with NIR-LLL induced transitory reduction of the excitability of the stimulated cortex. These findings give further insights into the mechanisms of TLS effects in the human cerebral cortex, paving the way for potential applications of TLS in treatment of stroke and in other clinical settings. Lasers Surg. Med. 45:648-653, 2013.
PB  - Wiley-Blackwell, Hoboken
T2  - Lasers in Surgery & Medicine
T1  - Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability
EP  - 653
IS  - 10
SP  - 648
VL  - 45
DO  - 10.1002/lsm.22190
ER  - 
@article{
author = "Konstantinović, Ljubica and Jelić, Milan and Jeremić, Aleksandra and Stevanović, Vuk and Milanović, Slađan and Filipović, Saša",
year = "2013",
abstract = "Background and Objective: Near-infrared low-level laser (NIR-LLL) irradiation penetrates scalp and skull and can reach superficial layers of the cerebral cortex. It was shown to improve the outcome of acute stroke in both animal and human studies. In this study we evaluated whether transcranial laser stimulation (TLS) with NIR-LLL can modulate the excitability of the motor cortex (M1) as measured by transcranial magnetic stimulation (TMS). Methods: TLS was applied for 5 minutes over the representation of the right first dorsal interosseal muscle (FDI) in left primary motor cortex (M1), in 14 healthy subjects. Motor evoked potentials (MEPs) from the FDI, elicited by single-pulse TMS, were measured at baseline and up to 30 minutes after the TLS. Results: The average MEP size was significantly reduced during the first 20 minutes following the TLS. The pattern was present in 10(71.5%) of the participants. The MEP size reduction correlated negatively with the motor threshold at rest. Conclusions: TLS with NIR-LLL induced transitory reduction of the excitability of the stimulated cortex. These findings give further insights into the mechanisms of TLS effects in the human cerebral cortex, paving the way for potential applications of TLS in treatment of stroke and in other clinical settings. Lasers Surg. Med. 45:648-653, 2013.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Lasers in Surgery & Medicine",
title = "Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability",
pages = "653-648",
number = "10",
volume = "45",
doi = "10.1002/lsm.22190"
}
Konstantinović, L., Jelić, M., Jeremić, A., Stevanović, V., Milanović, S.,& Filipović, S.. (2013). Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability. in Lasers in Surgery & Medicine
Wiley-Blackwell, Hoboken., 45(10), 648-653.
https://doi.org/10.1002/lsm.22190
Konstantinović L, Jelić M, Jeremić A, Stevanović V, Milanović S, Filipović S. Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability. in Lasers in Surgery & Medicine. 2013;45(10):648-653.
doi:10.1002/lsm.22190 .
Konstantinović, Ljubica, Jelić, Milan, Jeremić, Aleksandra, Stevanović, Vuk, Milanović, Slađan, Filipović, Saša, "Transcranial Application of Near-Infrared Low-Level Laser Can Modulate Cortical Excitability" in Lasers in Surgery & Medicine, 45, no. 10 (2013):648-653,
https://doi.org/10.1002/lsm.22190 . .
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