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Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression
(Hindawi Ltd, London, 2015)
Transforming growth factor-beta (TGF-beta) and oxidative stress/ReactiveOxygen Species (ROS) both have pivotal roles in health and disease. In this review we are analyzing the interplay between TGF-beta and ROS in tumorigenesis ...
Angiogenic factors are increased in circulating granulocytes and CD34(+) cells of myeloproliferative neoplasms
(Wiley-Blackwell, Hoboken, 2017)
It has been shown that angiogenesis and inflammation play an important role in development of most hematological malignancies including the myeloproliferative neoplasm (MPN). The aim of this study was to investigate and ...
Lack of effect of bioactive-rich extracts of pomegranate, persimmon, nettle, dill, kale and Sideritis and isolated bioactives on platelet function
(Wiley, Hoboken, 2013)
BACKGROUNDThe health benefits of fruit and vegetable-rich diets may be partly due to modulation of platelet activity by bioactive phytochemicals. The aim of this study was to investigate the effects of bioactive-rich plant ...
Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players
(Shanghai Univ Sport, Shanghai, 2017)
Background: Intensive exercise changes physiological need for glucose and several biochemical pathways responsible for its metabolism response. Among them are those which involve insulin, insulin-like growth factor (IGF-1), ...
Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
(Nature Publishing Group, London, 2017)
Chemotherapy in patients with inoperable or advanced breast cancer inevitably results in low-dose exposure of tumor-cell subset and senescence. Metabolically active senescent cells secrete multiple tumor promoting factors ...
Immobilization of Candida antarctica lipase B on kaolin and its application in synthesis of lipophilic antioxidants
(Elsevier Science Bv, Amsterdam, 2017)
Lipase B from Candida antarctica was immobilized by adsorption onto laboratory prepared metakaolin. This support has great potential for enzyme immobilization since it has good mechanical characteristics and thermal stability ...
Babesia microti infection changes host spleen architecture and is cleared by a Th1 immune response
(Frontiers in Microbiology, 2018)
Babesia microti is a malaria-like parasite, which infects ~2000 people annually, such that babesiosis is now a notifiable disease in the United States. Immunocompetent individuals often remain asymptomatic and are tested ...
Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand
(Elsevier Ireland Ltd, Clare, 2017)
Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled ...
The Acute Effect of Ethanol on Adrenal Cortex in Female Rats-Possible Role of Nitric Oxide
(Oxford Univ Press, Oxford, 2011)
Aims: The present study was designed to investigate a possible role of endogenous nitric oxide (NO) in the adrenal response to an acute alcohol administration in female rats. To this end, N(omega)-nitro-l-arginine-methyl ...
Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats
(Elsevier Science Bv, Amsterdam, 2018)
The potential beneficial effects of chronic consumption of dried chokeberry fruit extract (DCE) were evaluated in the present in vivo study. The study concentrates on haemodynamic parameters, lipid profile and oxidative ...