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The potential of interleukin-17 to mediate hematopoietic response
(Humana Press Inc, Totowa, 2012)
It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of ...
Combined effect of IL-17 and blockade of nitric oxide biosynthesis on haematopoiesis in mice
(Wiley, Hoboken, 2010)
Aim: The study was undertaken to extend our investigation concerning both the in vivo activity of interleukin (IL)-17 and the specific role of nitric oxide (NO) in IL-17-induced effects in the process of haematopoiesis. ...
p38 MAPK signaling mediates IL-17-induced nitric oxide synthase expression in bone marrow cells
(Taylor & Francis Ltd, Abingdon, 2009)
The effects of interleukin (IL)-17 on nitric oxide (NO) synthase (NOS) expression, as well as the participation of mitogen-activated protein kinases (MAPKs) in IL-17-mediated effects were examined in murine bone marrow ...
Hematopoietic changes and altered reactivity to IL-17 in Syphacia obvelata-infected mice
(Elsevier Ireland Ltd, Clare, 2006)
Pinworm parasites commonly infect laboratory mice with high prevalence even in well-managed animal colonies. Although often considered as irrelevant, these parasites if undetected may significantly interfere with the ...
Syphacia obvelata modifies mitogen-activated protein kinases and nitric oxide synthases expression in murine bone marrow cells
(Elsevier Ireland Ltd, Clare, 2010)
Syphacia obvelata is a rodent nematode parasite with high prevalence in laboratory mice. In our previous work we have demonstrated that this gut-dwelling helminth induces significant hematopoietic changes, characterized ...
Effect of IL-17 on in vitro hematopoietic progenitor cells growth and cytokine release in normal and post-irradiated murine bone marrow
(Taylor & Francis Ltd, Abingdon, 2001)
The influence of recombinant human IL-17 on granulocyte-macrophage (CFU-GM) and erythroid (BFU-E and CFU-E) progenitors and the release of IL-1 alpha/beta, IL-6 and erythropoietin (EPO) was estimated in the bone marrow ...
Low O-2 concentrations enhance the positive effect of IL-17 on the maintenance of erythroid progenitors during co-culture of CD34+and mesenchymal stem cells
(John Libbey Eurotext Ltd, Montrouge, 2009)
Co-culture of haematopoietic cells with a stromal cell layer does not mimic the physiological, micro-environmental niche, whose major feature is a low oxygen (O-2) concentration. Thus, in order to study the effects of IL-17 ...
Effects of il-17 on erythroid progenitors growth: involvement of mapks and gata transcription factors
(Biolife Sas, Silva Marina (Te), 2012)
Interleukin-17 is Th17 cell cytokine implicated in regulation of hematopoiesis and inflammation. Besides promoting granulopoiesis, we have previously shown that IL-17 also affects erythropoiesis stimulating the development ...
Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Interleukin-17 belongs to a family of pro-inflammatory cytokines with pleiotropic effects, which can be associated with several inflammatory diseases of the muscle tissue. Although elevated levels of interleukin-17 have ...
In vitro effects of IL-17 on angiogenic properties of endothelial cells in relation to oxygen levels
(Wiley, Hoboken, 2013)
The aim of this study has been to elucidate how different oxygen levels impact the effects of Interleukin-17 (IL-17) on angiogenic properties of endothelial cells. Two endothelial cell lines, mouse MS-1 and human EA.hy ...