It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of hematopoiesis was indicated by the line of evidence that IL-17 links T-cell function and hematopoiesis through stimulation of granulopoiesis and neutrophil trafficking. Furthermore, our data demonstrated that IL-17 also affects other cells of hematopoietic system, such as erythroid progenitors, as well as mesenchymal stem cells. In order to better understand the regulatory role of IL-17 in hematopoiesis, molecular mechanisms underlying the effects of IL-17 on hematopoietic and mesenchymal stem cells were also studied.
Keywords:
IL-17 / Hematopoiesis / Myeloid and erythroid progenitors / Bone marrow / Spleen
TY - JOUR
AU - Krstić, Aleksandra
AU - Mojsilović, Slavko
AU - Jovčić, Gordana
AU - Bugarski, Diana
PY - 2012
UR - http://rimi.imi.bg.ac.rs/handle/123456789/392
AB - It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of hematopoiesis was indicated by the line of evidence that IL-17 links T-cell function and hematopoiesis through stimulation of granulopoiesis and neutrophil trafficking. Furthermore, our data demonstrated that IL-17 also affects other cells of hematopoietic system, such as erythroid progenitors, as well as mesenchymal stem cells. In order to better understand the regulatory role of IL-17 in hematopoiesis, molecular mechanisms underlying the effects of IL-17 on hematopoietic and mesenchymal stem cells were also studied.
PB - Humana Press Inc, Totowa
T2 - Immunologic Research
T1 - The potential of interleukin-17 to mediate hematopoietic response
EP - 41
IS - 1-2
SP - 34
VL - 52
DO - 10.1007/s12026-012-8276-8
ER -
@article{
author = "Krstić, Aleksandra and Mojsilović, Slavko and Jovčić, Gordana and Bugarski, Diana",
year = "2012",
abstract = "It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of hematopoiesis was indicated by the line of evidence that IL-17 links T-cell function and hematopoiesis through stimulation of granulopoiesis and neutrophil trafficking. Furthermore, our data demonstrated that IL-17 also affects other cells of hematopoietic system, such as erythroid progenitors, as well as mesenchymal stem cells. In order to better understand the regulatory role of IL-17 in hematopoiesis, molecular mechanisms underlying the effects of IL-17 on hematopoietic and mesenchymal stem cells were also studied.",
publisher = "Humana Press Inc, Totowa",
journal = "Immunologic Research",
title = "The potential of interleukin-17 to mediate hematopoietic response",
pages = "41-34",
number = "1-2",
volume = "52",
doi = "10.1007/s12026-012-8276-8"
}
Krstić, A., Mojsilović, S., Jovčić, G.,& Bugarski, D.. (2012). The potential of interleukin-17 to mediate hematopoietic response. in Immunologic Research
Humana Press Inc, Totowa., 52(1-2), 34-41.
https://doi.org/10.1007/s12026-012-8276-8
Krstić A, Mojsilović S, Jovčić G, Bugarski D. The potential of interleukin-17 to mediate hematopoietic response. in Immunologic Research. 2012;52(1-2):34-41.
doi:10.1007/s12026-012-8276-8 .
Krstić, Aleksandra, Mojsilović, Slavko, Jovčić, Gordana, Bugarski, Diana, "The potential of interleukin-17 to mediate hematopoietic response" in Immunologic Research, 52, no. 1-2 (2012):34-41,
https://doi.org/10.1007/s12026-012-8276-8 . .
