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The potential of interleukin-17 to mediate hematopoietic response

Authorized Users Only
2012
Authors
Krstić, Aleksandra
Mojsilović, Slavko
Jovčić, Gordana
Bugarski, Diana
Article (Published version)
Metadata
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Abstract
It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of hematopoiesis was indicated by the line of evidence that IL-17 links T-cell function and hematopoiesis through stimulation of granulopoiesis and neutrophil trafficking. Furthermore, our data demonstrated that IL-17 also affects other cells of hematopoietic system, such as erythroid progenitors, as well as mesenchymal stem cells. In order to better understand the regulatory role of IL-17 in hematopoiesis, molecular mechanisms underlying the effects of IL-17 on hematopoietic and mesenchymal stem cells were also studied.
Keywords:
IL-17 / Hematopoiesis / Myeloid and erythroid progenitors / Bone marrow / Spleen
Source:
Immunologic Research, 2012, 52, 1-2, 34-41
Publisher:
  • Humana Press Inc, Totowa
Funding / projects:
  • Regenerative and modulatory potential of adult stem cells (RS-175062)

DOI: 10.1007/s12026-012-8276-8

ISSN: 0257-277X

PubMed: 22392050

WoS: 000303057600005

Scopus: 2-s2.0-84859916452
[ Google Scholar ]
47
44
URI
http://rimi.imi.bg.ac.rs/handle/123456789/392
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
Institut za medicinska istraživanja
TY  - JOUR
AU  - Krstić, Aleksandra
AU  - Mojsilović, Slavko
AU  - Jovčić, Gordana
AU  - Bugarski, Diana
PY  - 2012
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/392
AB  - It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of hematopoiesis was indicated by the line of evidence that IL-17 links T-cell function and hematopoiesis through stimulation of granulopoiesis and neutrophil trafficking. Furthermore, our data demonstrated that IL-17 also affects other cells of hematopoietic system, such as erythroid progenitors, as well as mesenchymal stem cells. In order to better understand the regulatory role of IL-17 in hematopoiesis, molecular mechanisms underlying the effects of IL-17 on hematopoietic and mesenchymal stem cells were also studied.
PB  - Humana Press Inc, Totowa
T2  - Immunologic Research
T1  - The potential of interleukin-17 to mediate hematopoietic response
EP  - 41
IS  - 1-2
SP  - 34
VL  - 52
DO  - 10.1007/s12026-012-8276-8
UR  - conv_2733
ER  - 
@article{
author = "Krstić, Aleksandra and Mojsilović, Slavko and Jovčić, Gordana and Bugarski, Diana",
year = "2012",
abstract = "It has long been known that T cells have the potential to modulate hematopoietic response in different ways. More recently, the importance of interleukin (IL)-17-secreting Th17 cells in T-cell-mediated regulation of hematopoiesis was indicated by the line of evidence that IL-17 links T-cell function and hematopoiesis through stimulation of granulopoiesis and neutrophil trafficking. Furthermore, our data demonstrated that IL-17 also affects other cells of hematopoietic system, such as erythroid progenitors, as well as mesenchymal stem cells. In order to better understand the regulatory role of IL-17 in hematopoiesis, molecular mechanisms underlying the effects of IL-17 on hematopoietic and mesenchymal stem cells were also studied.",
publisher = "Humana Press Inc, Totowa",
journal = "Immunologic Research",
title = "The potential of interleukin-17 to mediate hematopoietic response",
pages = "41-34",
number = "1-2",
volume = "52",
doi = "10.1007/s12026-012-8276-8",
url = "conv_2733"
}
Krstić, A., Mojsilović, S., Jovčić, G.,& Bugarski, D.. (2012). The potential of interleukin-17 to mediate hematopoietic response. in Immunologic Research
Humana Press Inc, Totowa., 52(1-2), 34-41.
https://doi.org/10.1007/s12026-012-8276-8
conv_2733
Krstić A, Mojsilović S, Jovčić G, Bugarski D. The potential of interleukin-17 to mediate hematopoietic response. in Immunologic Research. 2012;52(1-2):34-41.
doi:10.1007/s12026-012-8276-8
conv_2733 .
Krstić, Aleksandra, Mojsilović, Slavko, Jovčić, Gordana, Bugarski, Diana, "The potential of interleukin-17 to mediate hematopoietic response" in Immunologic Research, 52, no. 1-2 (2012):34-41,
https://doi.org/10.1007/s12026-012-8276-8 .,
conv_2733 .

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