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Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells
(Amer Soc Hematology, Washington, 2008)
Hydroxyurea, a drug widely used for treating myeloproliferative diseases, has also been approved for the treatment of sickle cell disease by raising fetal hemoglobin (HbF). We have shown that nitric oxide (NO) and the ...
The metabolic syndrome, an epidemic among HIV-infected patients on HAART
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2009)
Background: HAART has dramatically changed the prognosis of AIDS, but has led to long-term toxicities of antiretroviral drugs. A major chronic complication is the metabolic syndrome (MS), including hyperlipidemia, lipodystrophy ...
The use of single-donor fibrin glue prepared by recycled cryoprecipitation in experimental liver surgery
(Vsp Bv, Leiden, 2002)
The purpose of the study was to evaluate the hemostatic effectiveness of fibrin glue (FG) prepared by a modification of cryoprecipitation technique in experimental rat liver surgery. FG component I was prepared by triple ...
Ruptured abdominal aortic aneurysms: Factors influencing early survival
(Elsevier Science Inc, New York, 2005)
In this study we aimed to define relevant prognostic predictors for the outcome of surgical treatment of ruptured abdominal aortic aneurysms. The study included 406 consecutive patients treated between January 1991 and ...
Comparison of a commercial ELISA with the modified agglutination test for the detection of Toxoplasma gondii infection in naturally exposed sheep
(Wiley, Hoboken, 2007)
Surprisingly few commercial ELISAs are available for the detection of Toxoplasma gondii infection in animals, and none for use in sheep have been evaluated. We thus compared the Bommeli Diagnostics ELISA Toxotest for the ...
Veterinary information management system (VIMS) in the process of notification and management of animal diseases / Veterinarski informacioni menadžment sistem (VIMS) u procesu prijavljivanja i menadžmenta zaraznih bolesti
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2009)
A prerequisite to the development of an efficient animal health, food safety and traceability management system in the animal food production chain is the implementation of an integrated veterinary informational management ...
Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production
(Elsevier Science Inc, New York, 2009)
Objective. We have previously shown that nitric oxide (NO) is involved in the hydroxyurea-induced increase of gamma-globin gene expression in cultured human erythroid progenitor cells and that hydroxyurea increases NO ...
The Prognosis of Pediatric AIDS in Serbia
(Bentham Science Publ Ltd, Sharjah, 2009)
To determine the outcome of HIV infection in children in a resource-limited setting, a retrospective analysis of a series of 51 pediatric cases from the Serbian cohort of HIV infected patients was performed. Twenty seven ...
Effects of Nitric Oxide on Red Blood Cell Development and Phenotype
(Current Topics in Developmental Biology, 2008)
Nitric oxide (NO) is a diffusible free radical generated primarily by NO synthases (NOS), isoenzymes that convert the l-arginine and molecular oxygen to citrulline and NO in cells. Endothelial cells as well as macrophages, ...