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The prognosis of patients with dissociated virological and immunological responses to HAART
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2010)
Background. - While HAART allows for the reconstitution of immune functions in most treated HIV patients, failure to achieve a significant increase in circulating CD4+ T cells despite undetectable viremia occurs. Methods. ...
New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2010)
Three new complexes of the general formula L[RuCl3(DMSO)(3)] (1-3), where L = chlorpromazine hydrochloride, trifluoroperazine dihydrochloride or thioridazine hydrochloride, were prepared and characterized by elemental ...
SKIP is required for TGF-beta 1-induced epithelial mesenchymal transition and migration in transformed keratinocytes
(Wiley, Hoboken, 2010)
Transforming growth factor-beta 1 (TGF-beta 1) potently induces the epithelial-mesenchymal transition (EMT) during tumoral progression. Although Sky-interacting protein (SKIP) regulates TGF-beta 1-induced Smad activation, ...
Toxoplasmosis in Serbia: time for an action plan
(EDP Sciences S A, Les Ulis Cedex A, 2010)
Known for a century, Toxoplasma gondii has been studied in Serbia half this time, ever since the introduction of the Sabin-Feldman test at the Institute for Medical Research (IMR) in 1959. However, despite 50 years of ...
Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia
(Akademiai Kiado Zrt, Budapest, 2010)
Anaplasma phagocytophilum strains from different geographical regions are characterised by diverse potential infectivity for humans and domesticated animals. We investigated the potential pathogenicity of A. phagocytophilum ...
Physiological and public health basis for assessing micronutrient requirements in children and adolescents. The EURRECA network
(Wiley, Hoboken, 2010)
This paper provides an overview of the current knowledge relating to the nutritional requirements and corresponding recommended nutrient intake values of children and adolescents for micronutrients and specificities related ...
Rac1 modulates TGF-beta 1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes
(Elsevier Science Bv, Amsterdam, 2010)
Transforming growth factor-beta 1 (TGF-beta 1) activates Rac1 GTPase in mouse transformed keratinocytes. Expression of a constitutively active Q61LRac1 mutant induced an epithelial to mesenchymal transition (EMT) linked ...
The Role of the TGF-beta Coreceptor Endoglin in Cancer
(Hindawi Ltd, London, 2010)
Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-beta) that interacts with type I and type II TGF-beta receptors and modulates TGF-beta signaling. Endoglin is overexpressed in the ...
Combined effect of IL-17 and blockade of nitric oxide biosynthesis on haematopoiesis in mice
(Wiley, Hoboken, 2010)
Aim: The study was undertaken to extend our investigation concerning both the in vivo activity of interleukin (IL)-17 and the specific role of nitric oxide (NO) in IL-17-induced effects in the process of haematopoiesis. ...
Seasonal Variations in Human Toxoplasma Infection in Serbia
(Mary Ann Liebert, Inc, New Rochelle, 2010)
Background: Seasonal variations in the occurrence of toxoplasmosis have been studied only sporadically. We thus examined the seasonal distribution of acute toxoplasmosis in Serbia during a 4-year period (2004-2008). Materials ...