TY  - JOUR
AU  - Ćujić, Nada
AU  - Savikin, Katarina
AU  - Miloradović, Zoran
AU  - Ivanov, Milan
AU  - Vajić, Una Jovana
AU  - Karanović, Danijela
AU  - Grujić-Milanović, Jelica
AU  - Jovović, Đurđica
AU  - Mihailović-Stanojević, Nevena
PY  - 2018
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/894
AB  - The potential beneficial effects of chronic consumption of dried chokeberry fruit extract (DCE) were evaluated in the present in vivo study. The study concentrates on haemodynamic parameters, lipid profile and oxidative stress in spontaneously hypertensive rats. DCE was characterized by HPLC/DAD method and individual anthocyanins, phenolic acids, and flavonoids were determined. Four week administration of DCE, rich in polyphenols, especially anthocyanins, significantly reduced systolic (P  lt  0.05), pulse pressure (P  lt  0.05) compared to control group, probably via significantly increased diuresis (P  lt  0.05). Significant decrease of plasma and erythrocytes TBARS was also found in the treated group. DCE consumption reduced lipid peroxidation through improving plasma FRAP reducing (P  lt  0.01). The activity of SOD in the treated group had been significantly lower (P  lt  0.01) compared to the control group. These results suggest that DCE could exert beneficial effects on cardiovascular health and has a potential as a nutritional supplement in arterial hypertension.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Functional Foods
T1  - Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats
EP  - 339
SP  - 330
VL  - 44
DO  - 10.1016/j.jff.2018.02.027
ER  - 

@article{
author = "Ćujić, Nada and Savikin, Katarina and Miloradović, Zoran and Ivanov, Milan and Vajić, Una Jovana and Karanović, Danijela and Grujić-Milanović, Jelica and Jovović, Đurđica and Mihailović-Stanojević, Nevena",
year = "2018",
abstract = "The potential beneficial effects of chronic consumption of dried chokeberry fruit extract (DCE) were evaluated in the present in vivo study. The study concentrates on haemodynamic parameters, lipid profile and oxidative stress in spontaneously hypertensive rats. DCE was characterized by HPLC/DAD method and individual anthocyanins, phenolic acids, and flavonoids were determined. Four week administration of DCE, rich in polyphenols, especially anthocyanins, significantly reduced systolic (P  lt  0.05), pulse pressure (P  lt  0.05) compared to control group, probably via significantly increased diuresis (P  lt  0.05). Significant decrease of plasma and erythrocytes TBARS was also found in the treated group. DCE consumption reduced lipid peroxidation through improving plasma FRAP reducing (P  lt  0.01). The activity of SOD in the treated group had been significantly lower (P  lt  0.01) compared to the control group. These results suggest that DCE could exert beneficial effects on cardiovascular health and has a potential as a nutritional supplement in arterial hypertension.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Functional Foods",
title = "Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats",
pages = "339-330",
volume = "44",
doi = "10.1016/j.jff.2018.02.027"
}

Ćujić, N., Savikin, K., Miloradović, Z., Ivanov, M., Vajić, U. J., Karanović, D., Grujić-Milanović, J., Jovović, Đ.,& Mihailović-Stanojević, N.. (2018). Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats. in Journal of Functional Foods
Elsevier Science Bv, Amsterdam., 44, 330-339.
https://doi.org/10.1016/j.jff.2018.02.027

Ćujić N, Savikin K, Miloradović Z, Ivanov M, Vajić UJ, Karanović D, Grujić-Milanović J, Jovović Đ, Mihailović-Stanojević N. Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats. in Journal of Functional Foods. 2018;44:330-339.
doi:10.1016/j.jff.2018.02.027 .

Ćujić, Nada, Savikin, Katarina, Miloradović, Zoran, Ivanov, Milan, Vajić, Una Jovana, Karanović, Danijela, Grujić-Milanović, Jelica, Jovović, Đurđica, Mihailović-Stanojević, Nevena, "Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats" in Journal of Functional Foods, 44 (2018):330-339,
https://doi.org/10.1016/j.jff.2018.02.027 . .

TY  - JOUR
AU  - Mihailović-Stanojević, Nevena
AU  - Savikin, Katarina
AU  - Živković, Jelena
AU  - Zdunić, Gordana
AU  - Miloradović, Zoran
AU  - Ivanov, Milan
AU  - Karanović, Danijela
AU  - Vajić, Una Jovana
AU  - Jovović, Đurđica
AU  - Grujić-Milanović, Jelica
PY  - 2016
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/691
AB  - Numerous studies have shown that moderate wine consumption is associated with decreased incidence of cardiovascular disease, including hypertension. Others observed that moderate alcohol consumption lowers the risk of cardiovascular events. The aim of the present study was to identify and quantify the components of red wine (RW) and alcohol-free red wine (AFRW), and compare the effects of their 4-week consumption (1 mL/day) on haemodynamics, lipid profile and oxidative stress in adult male spontaneously hypertensive rats (SHR). Among anthocyanins, malvidin 3-O-glucoside dominates in both RW and AFRW. AFRW reduces blood pressure of SHR. Both RW and AFRW can increase antioxidant capacity and reduce susceptibility of plasma to lipid peroxidation. RW, due to adverse triacylglycerol levels elevates the risk of cardiovascular complications in SHR. Removing alcohol from wine eliminates these adverse effects and promotes AFRW as a useful beverage in hypertensive patients.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Functional Foods
T1  - Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine
EP  - 730
SP  - 719
VL  - 26
DO  - 10.1016/j.jff.2016.08.051
ER  - 

@article{
author = "Mihailović-Stanojević, Nevena and Savikin, Katarina and Živković, Jelena and Zdunić, Gordana and Miloradović, Zoran and Ivanov, Milan and Karanović, Danijela and Vajić, Una Jovana and Jovović, Đurđica and Grujić-Milanović, Jelica",
year = "2016",
abstract = "Numerous studies have shown that moderate wine consumption is associated with decreased incidence of cardiovascular disease, including hypertension. Others observed that moderate alcohol consumption lowers the risk of cardiovascular events. The aim of the present study was to identify and quantify the components of red wine (RW) and alcohol-free red wine (AFRW), and compare the effects of their 4-week consumption (1 mL/day) on haemodynamics, lipid profile and oxidative stress in adult male spontaneously hypertensive rats (SHR). Among anthocyanins, malvidin 3-O-glucoside dominates in both RW and AFRW. AFRW reduces blood pressure of SHR. Both RW and AFRW can increase antioxidant capacity and reduce susceptibility of plasma to lipid peroxidation. RW, due to adverse triacylglycerol levels elevates the risk of cardiovascular complications in SHR. Removing alcohol from wine eliminates these adverse effects and promotes AFRW as a useful beverage in hypertensive patients.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Functional Foods",
title = "Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine",
pages = "730-719",
volume = "26",
doi = "10.1016/j.jff.2016.08.051"
}

Mihailović-Stanojević, N., Savikin, K., Živković, J., Zdunić, G., Miloradović, Z., Ivanov, M., Karanović, D., Vajić, U. J., Jovović, Đ.,& Grujić-Milanović, J.. (2016). Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine. in Journal of Functional Foods
Elsevier Science Bv, Amsterdam., 26, 719-730.
https://doi.org/10.1016/j.jff.2016.08.051

Mihailović-Stanojević N, Savikin K, Živković J, Zdunić G, Miloradović Z, Ivanov M, Karanović D, Vajić UJ, Jovović Đ, Grujić-Milanović J. Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine. in Journal of Functional Foods. 2016;26:719-730.
doi:10.1016/j.jff.2016.08.051 .

Mihailović-Stanojević, Nevena, Savikin, Katarina, Živković, Jelena, Zdunić, Gordana, Miloradović, Zoran, Ivanov, Milan, Karanović, Danijela, Vajić, Una Jovana, Jovović, Đurđica, Grujić-Milanović, Jelica, "Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine" in Journal of Functional Foods, 26 (2016):719-730,
https://doi.org/10.1016/j.jff.2016.08.051 . .

TY  - JOUR
AU  - Đekić-Ivanković, Marija
AU  - Weiler, Hope
AU  - Nikolić, Marina
AU  - Kadvan, Agnes
AU  - Gurinović, Mirjana
AU  - Mandić, Ljuba M.
AU  - Glibetić, Marija
PY  - 2016
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/729
AB  - Objective: The objective of the present study was to examine the external validity of an FFQ designed to estimate dietary vitamin D intake compared with a plasma biomarker and three repeated 24 h dietary recalls in women of reproductive age in Serbia, where there is no exposure to food fortified with vitamin D. The method of triads was applied. Design: In a cross-sectional study, 422 women completed the Women and Reproductive Health FFQ (WRH-FFQ) during the winter months. From a representative subgroup (n 44), three 24 h dietary recalls and anthropometric parameters were collected as well as a fasting blood sample for vitamin D biomarker analyses. Correlation coefficients were calculated between each of the dietary methods. Validity coefficients, as a correlation between the measured and estimated 'true' exposure, were calculated using the method of triads. Bland-Altman plots were also constructed. Setting: Three major universities in Serbia. Subjects: Healthy young women (n 422) aged 18-35 years. Results: The WRH-FFQ estimate of vitamin D intake for all participants was 4.0 (SD 3.3) mu g/d and 3.1 (SD 2.3) mu g/d for the subgroup. Bland-Altman plots for these intakes showed high agreement. Validity coefficients for the FFQ, 24 h recall and biomarker were. rho(QI) = 0.847 (95 % CI 0.564, 0.928), rho(RI) = 0.810 (95 % CI 0.537, 0.997) and rho(BI) = 0.499 (95 % CI 0.190, 0.840), while the correlation coefficients were 0.686, 0.422 and 0.404. Conclusions: The FFQ applied in the present study is a valid tool for assessing dietary vitamin D intake in women living in Serbia, a region without mandatory vitamin D food fortification.
PB  - Cambridge Univ Press, Cambridge
T2  - Public Health Nutrition
T1  - Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model
EP  - 445
IS  - 4
SP  - 437
VL  - 19
DO  - 10.1017/S136898001500138X
ER  - 

@article{
author = "Đekić-Ivanković, Marija and Weiler, Hope and Nikolić, Marina and Kadvan, Agnes and Gurinović, Mirjana and Mandić, Ljuba M. and Glibetić, Marija",
year = "2016",
abstract = "Objective: The objective of the present study was to examine the external validity of an FFQ designed to estimate dietary vitamin D intake compared with a plasma biomarker and three repeated 24 h dietary recalls in women of reproductive age in Serbia, where there is no exposure to food fortified with vitamin D. The method of triads was applied. Design: In a cross-sectional study, 422 women completed the Women and Reproductive Health FFQ (WRH-FFQ) during the winter months. From a representative subgroup (n 44), three 24 h dietary recalls and anthropometric parameters were collected as well as a fasting blood sample for vitamin D biomarker analyses. Correlation coefficients were calculated between each of the dietary methods. Validity coefficients, as a correlation between the measured and estimated 'true' exposure, were calculated using the method of triads. Bland-Altman plots were also constructed. Setting: Three major universities in Serbia. Subjects: Healthy young women (n 422) aged 18-35 years. Results: The WRH-FFQ estimate of vitamin D intake for all participants was 4.0 (SD 3.3) mu g/d and 3.1 (SD 2.3) mu g/d for the subgroup. Bland-Altman plots for these intakes showed high agreement. Validity coefficients for the FFQ, 24 h recall and biomarker were. rho(QI) = 0.847 (95 % CI 0.564, 0.928), rho(RI) = 0.810 (95 % CI 0.537, 0.997) and rho(BI) = 0.499 (95 % CI 0.190, 0.840), while the correlation coefficients were 0.686, 0.422 and 0.404. Conclusions: The FFQ applied in the present study is a valid tool for assessing dietary vitamin D intake in women living in Serbia, a region without mandatory vitamin D food fortification.",
publisher = "Cambridge Univ Press, Cambridge",
journal = "Public Health Nutrition",
title = "Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model",
pages = "445-437",
number = "4",
volume = "19",
doi = "10.1017/S136898001500138X"
}

Đekić-Ivanković, M., Weiler, H., Nikolić, M., Kadvan, A., Gurinović, M., Mandić, L. M.,& Glibetić, M.. (2016). Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model. in Public Health Nutrition
Cambridge Univ Press, Cambridge., 19(4), 437-445.
https://doi.org/10.1017/S136898001500138X

Đekić-Ivanković M, Weiler H, Nikolić M, Kadvan A, Gurinović M, Mandić LM, Glibetić M. Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model. in Public Health Nutrition. 2016;19(4):437-445.
doi:10.1017/S136898001500138X .

Đekić-Ivanković, Marija, Weiler, Hope, Nikolić, Marina, Kadvan, Agnes, Gurinović, Mirjana, Mandić, Ljuba M., Glibetić, Marija, "Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model" in Public Health Nutrition, 19, no. 4 (2016):437-445,
https://doi.org/10.1017/S136898001500138X . .

TY  - JOUR
AU  - Vajić, Una Jovana
AU  - Grujić-Milanović, Jelica
AU  - Živković, Jelena
AU  - Savikin, Katarina
AU  - Gođevac, Dejan
AU  - Miloradović, Zoran
AU  - Bugarski, Branko
AU  - Mihailović-Stanojević, Nevena
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/669
AB  - A full three level factorial design was implemented for optimization of extraction parameters in order to maximize total phenolic (TP) yield from stinging nettle leaf. Factors considered were percentage of methanol in solvent (X-1 : 50-100% methanol) and extraction time (X-2: 30-90 min), and maceration was used as extraction method. A second-order polynomial model was applied for fitting experimental data and predicting the response, and this mathematical model produced a satisfactory fit (R-2 = 0.993,p lt 0.01). The optimal extraction conditions were 54% aqueous methanol and 38 min extraction time, while maximal theoretical TP yield was 8.9 mg GAE/g DW. Solvent composition significantly affected extraction efficiency causing decrease of TP yield with increase of methanol percentage. On the other hand, extraction time did not influence significantly efficiency of extraction. Using LC/MS and HPLC analysis we detected and quantified three most abundant phenolic compounds: 2-O-caffeoyl malic acid, chlorogenic acid, and rutin. Comparison between maceration and ultrasound-assisted extraction (UAE) obtained extracts based on TP content as well as antiradical activity and HPLC results, showed that UAE have a better extraction capability affecting yield and time of extraction. Of all tested extracts, 54% aqueous methanolic extracts obtained with UAE and 38 min extraction time had the highest TP content.
PB  - Elsevier, Amsterdam
T2  - Industrial Crops & Products
T1  - Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology
EP  - 917
SP  - 912
VL  - 74
DO  - 10.1016/j.indcrop.2015.06.032
ER  - 

@article{
author = "Vajić, Una Jovana and Grujić-Milanović, Jelica and Živković, Jelena and Savikin, Katarina and Gođevac, Dejan and Miloradović, Zoran and Bugarski, Branko and Mihailović-Stanojević, Nevena",
year = "2015",
abstract = "A full three level factorial design was implemented for optimization of extraction parameters in order to maximize total phenolic (TP) yield from stinging nettle leaf. Factors considered were percentage of methanol in solvent (X-1 : 50-100% methanol) and extraction time (X-2: 30-90 min), and maceration was used as extraction method. A second-order polynomial model was applied for fitting experimental data and predicting the response, and this mathematical model produced a satisfactory fit (R-2 = 0.993,p lt 0.01). The optimal extraction conditions were 54% aqueous methanol and 38 min extraction time, while maximal theoretical TP yield was 8.9 mg GAE/g DW. Solvent composition significantly affected extraction efficiency causing decrease of TP yield with increase of methanol percentage. On the other hand, extraction time did not influence significantly efficiency of extraction. Using LC/MS and HPLC analysis we detected and quantified three most abundant phenolic compounds: 2-O-caffeoyl malic acid, chlorogenic acid, and rutin. Comparison between maceration and ultrasound-assisted extraction (UAE) obtained extracts based on TP content as well as antiradical activity and HPLC results, showed that UAE have a better extraction capability affecting yield and time of extraction. Of all tested extracts, 54% aqueous methanolic extracts obtained with UAE and 38 min extraction time had the highest TP content.",
publisher = "Elsevier, Amsterdam",
journal = "Industrial Crops & Products",
title = "Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology",
pages = "917-912",
volume = "74",
doi = "10.1016/j.indcrop.2015.06.032"
}

Vajić, U. J., Grujić-Milanović, J., Živković, J., Savikin, K., Gođevac, D., Miloradović, Z., Bugarski, B.,& Mihailović-Stanojević, N.. (2015). Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology. in Industrial Crops & Products
Elsevier, Amsterdam., 74, 912-917.
https://doi.org/10.1016/j.indcrop.2015.06.032

Vajić UJ, Grujić-Milanović J, Živković J, Savikin K, Gođevac D, Miloradović Z, Bugarski B, Mihailović-Stanojević N. Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology. in Industrial Crops & Products. 2015;74:912-917.
doi:10.1016/j.indcrop.2015.06.032 .

Vajić, Una Jovana, Grujić-Milanović, Jelica, Živković, Jelena, Savikin, Katarina, Gođevac, Dejan, Miloradović, Zoran, Bugarski, Branko, Mihailović-Stanojević, Nevena, "Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology" in Industrial Crops & Products, 74 (2015):912-917,
https://doi.org/10.1016/j.indcrop.2015.06.032 . .

TY  - JOUR
AU  - Konić-Ristić, Aleksandra
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Besu, Irina
AU  - Menković, Nebojša
AU  - Glibetić, Marija
AU  - Srdić-Rajić, Tatjana
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/660
AB  - The role of saliva in maintaining oral health and homeostasis is based on its physicochemical properties and biological activities of its components, including salivary immunoglobulin A (IgA). Both salivary rates and immunological status of saliva are found to be compromised in smokers. The aim of this study was to investigate the acute time-dependent effect of smoking and black currant consumption on the salivary flow rate (SFR) and salivary IgA secretion rate (sIgA SR) in healthy smokers. SFR, sIgA levels in saliva, and sIgA SRs were determined in healthy smokers (n=8) at eight times of assessment within three consecutive interventions: at the baseline; 5, 30, and 60 min after smoking; 5, 30, and 60 min after black currant consumption (100 g), followed by smoking; and 5 min after black currant consumption. Smoking induced a significant delayed effect on SFR measured 60 min after smoking (P=.03), while black currant consumption preceding smoking prevented that effect. Salivary IgA concentrations and sIgA flow rates were not acutely influenced by smoking. Black currant consumption preceding smoking induced a significant decrease in sIgA concentrations 5 min after the intervention compared with the baseline (P=.046), with a further increasing trend, statistically significant, 60 min after the intervention (P=.025). Although smoking cessation is the most important strategy in the prevention of chronic diseases, the obtained results suggest that the influence of black currant consumption on negative effects of tobacco smoke on salivary flow and immunological status of saliva could partly reduce the smoking-associated risk on oral health.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Acute Effects of Black Currant Consumption on Salivary Flow Rate and Secretion Rate of Salivary Immunoglobulin A in Healthy Smokers
EP  - 488
IS  - 4
SP  - 483
VL  - 18
DO  - 10.1089/jmf.2013.0149
ER  - 

@article{
author = "Konić-Ristić, Aleksandra and Savikin, Katarina and Zdunić, Gordana and Besu, Irina and Menković, Nebojša and Glibetić, Marija and Srdić-Rajić, Tatjana",
year = "2015",
abstract = "The role of saliva in maintaining oral health and homeostasis is based on its physicochemical properties and biological activities of its components, including salivary immunoglobulin A (IgA). Both salivary rates and immunological status of saliva are found to be compromised in smokers. The aim of this study was to investigate the acute time-dependent effect of smoking and black currant consumption on the salivary flow rate (SFR) and salivary IgA secretion rate (sIgA SR) in healthy smokers. SFR, sIgA levels in saliva, and sIgA SRs were determined in healthy smokers (n=8) at eight times of assessment within three consecutive interventions: at the baseline; 5, 30, and 60 min after smoking; 5, 30, and 60 min after black currant consumption (100 g), followed by smoking; and 5 min after black currant consumption. Smoking induced a significant delayed effect on SFR measured 60 min after smoking (P=.03), while black currant consumption preceding smoking prevented that effect. Salivary IgA concentrations and sIgA flow rates were not acutely influenced by smoking. Black currant consumption preceding smoking induced a significant decrease in sIgA concentrations 5 min after the intervention compared with the baseline (P=.046), with a further increasing trend, statistically significant, 60 min after the intervention (P=.025). Although smoking cessation is the most important strategy in the prevention of chronic diseases, the obtained results suggest that the influence of black currant consumption on negative effects of tobacco smoke on salivary flow and immunological status of saliva could partly reduce the smoking-associated risk on oral health.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Acute Effects of Black Currant Consumption on Salivary Flow Rate and Secretion Rate of Salivary Immunoglobulin A in Healthy Smokers",
pages = "488-483",
number = "4",
volume = "18",
doi = "10.1089/jmf.2013.0149"
}

Konić-Ristić, A., Savikin, K., Zdunić, G., Besu, I., Menković, N., Glibetić, M.,& Srdić-Rajić, T.. (2015). Acute Effects of Black Currant Consumption on Salivary Flow Rate and Secretion Rate of Salivary Immunoglobulin A in Healthy Smokers. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 18(4), 483-488.
https://doi.org/10.1089/jmf.2013.0149

Konić-Ristić A, Savikin K, Zdunić G, Besu I, Menković N, Glibetić M, Srdić-Rajić T. Acute Effects of Black Currant Consumption on Salivary Flow Rate and Secretion Rate of Salivary Immunoglobulin A in Healthy Smokers. in Journal of Medicinal Food. 2015;18(4):483-488.
doi:10.1089/jmf.2013.0149 .

Konić-Ristić, Aleksandra, Savikin, Katarina, Zdunić, Gordana, Besu, Irina, Menković, Nebojša, Glibetić, Marija, Srdić-Rajić, Tatjana, "Acute Effects of Black Currant Consumption on Salivary Flow Rate and Secretion Rate of Salivary Immunoglobulin A in Healthy Smokers" in Journal of Medicinal Food, 18, no. 4 (2015):483-488,
https://doi.org/10.1089/jmf.2013.0149 . .

TY  - JOUR
AU  - Kardum, Nevena Đ.
AU  - Milovanović, Branislav
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Mutavdzin, Slavica
AU  - Gligorijević, Tatjana
AU  - Spasić, Slavica
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/621
AB  - Epidemiological studies have shown a positive association between intake of foods rich in antioxidants and lower incidence of cardiovascular disease development. Polyphenols are considered the most abundant and important dietary antioxidants. The aim of this study was to evaluate effects of polyphenol-rich chokeberry juice consumption on 24-h ambulatory monitored blood pressure (BP) level in subjects with no pharmacologically treated high normal BP or grade I hypertension. Twenty-three subjects (12 men and 11 women) aged 33-67 were enrolled and instructed to consume 200mL of juice daily for 4 weeks. Participants were divided in two groups, based on prevalence of sympathetic or parasympathetic activity. Measurements of biochemical parameters and heart rate variability analysis were also applied. At the end of the intervention period, average 24-h and awake systolic and diastolic BP were significantly decreased (P lt .05). This was more pronounced in the group with prevalence of sympathetic activity. Significant reduction in triglyceride level (P lt .05) and a reducing effect on total and low-density lipoprotein cholesterol were also found. Obtained results indicate a positive impact of regular chokeberry juice consumption on BP and lipid status in pharmacologically untreated hypertensive subjects.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects
EP  - 1238
IS  - 11
SP  - 1231
VL  - 18
DO  - 10.1089/jmf.2014.0171
ER  - 

@article{
author = "Kardum, Nevena Đ. and Milovanović, Branislav and Savikin, Katarina and Zdunić, Gordana and Mutavdzin, Slavica and Gligorijević, Tatjana and Spasić, Slavica",
year = "2015",
abstract = "Epidemiological studies have shown a positive association between intake of foods rich in antioxidants and lower incidence of cardiovascular disease development. Polyphenols are considered the most abundant and important dietary antioxidants. The aim of this study was to evaluate effects of polyphenol-rich chokeberry juice consumption on 24-h ambulatory monitored blood pressure (BP) level in subjects with no pharmacologically treated high normal BP or grade I hypertension. Twenty-three subjects (12 men and 11 women) aged 33-67 were enrolled and instructed to consume 200mL of juice daily for 4 weeks. Participants were divided in two groups, based on prevalence of sympathetic or parasympathetic activity. Measurements of biochemical parameters and heart rate variability analysis were also applied. At the end of the intervention period, average 24-h and awake systolic and diastolic BP were significantly decreased (P lt .05). This was more pronounced in the group with prevalence of sympathetic activity. Significant reduction in triglyceride level (P lt .05) and a reducing effect on total and low-density lipoprotein cholesterol were also found. Obtained results indicate a positive impact of regular chokeberry juice consumption on BP and lipid status in pharmacologically untreated hypertensive subjects.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects",
pages = "1238-1231",
number = "11",
volume = "18",
doi = "10.1089/jmf.2014.0171"
}

Kardum, N. Đ., Milovanović, B., Savikin, K., Zdunić, G., Mutavdzin, S., Gligorijević, T.,& Spasić, S.. (2015). Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 18(11), 1231-1238.
https://doi.org/10.1089/jmf.2014.0171

Kardum NĐ, Milovanović B, Savikin K, Zdunić G, Mutavdzin S, Gligorijević T, Spasić S. Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects. in Journal of Medicinal Food. 2015;18(11):1231-1238.
doi:10.1089/jmf.2014.0171 .

Kardum, Nevena Đ., Milovanović, Branislav, Savikin, Katarina, Zdunić, Gordana, Mutavdzin, Slavica, Gligorijević, Tatjana, Spasić, Slavica, "Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects" in Journal of Medicinal Food, 18, no. 11 (2015):1231-1238,
https://doi.org/10.1089/jmf.2014.0171 . .

TY  - JOUR
AU  - Kardum, Nevena Đ.
AU  - Takić, Marija.
AU  - Savikin, Katarina
AU  - Zec, Manja M.
AU  - Zdunić, Gordana
AU  - Spasić, Slavica
AU  - Konić-Ristić, Aleksandra
PY  - 2014
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/583
AB  - The effect of long-term polyphenol-rich chokeberry juice consumption on activities of antioxidant enzymes and membrane lipid status in erythrocytes of 25 healthy women was examined. Percentages of membrane fatty acids, superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities were assessed at a baseline, in the middle and at the end of a 3-month-long consumption period. A significant increase in C22:6n-3, n-3 polyunsaturated fatty acids (PUFAs), total PUFAs and unsaturation index and a significant decrease in monounsaturated fatty acids (MUFAs) and n-6:n-3 ratio were found. Significantly higher SOD and GP(x) activities were also recorded at the end of the study. Serum lipids and glucose were stabile during the consumption period, while the levels of thiobarbituric acid-reactive substances (TBARS), as serum indicator of lipid peroxidation, were reduced significantly. These results indicate a positive impact of regular chokeberry juice consumption on cellular oxidative damage and suggest its putative role in the protection against oxidative stress.
PB  - Elsevier, Amsterdam
T2  - Journal of Functional Foods
T1  - Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women
EP  - 97
SP  - 89
VL  - 9
DO  - 10.1016/j.jff.2014.04.019
ER  - 

@article{
author = "Kardum, Nevena Đ. and Takić, Marija. and Savikin, Katarina and Zec, Manja M. and Zdunić, Gordana and Spasić, Slavica and Konić-Ristić, Aleksandra",
year = "2014",
abstract = "The effect of long-term polyphenol-rich chokeberry juice consumption on activities of antioxidant enzymes and membrane lipid status in erythrocytes of 25 healthy women was examined. Percentages of membrane fatty acids, superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities were assessed at a baseline, in the middle and at the end of a 3-month-long consumption period. A significant increase in C22:6n-3, n-3 polyunsaturated fatty acids (PUFAs), total PUFAs and unsaturation index and a significant decrease in monounsaturated fatty acids (MUFAs) and n-6:n-3 ratio were found. Significantly higher SOD and GP(x) activities were also recorded at the end of the study. Serum lipids and glucose were stabile during the consumption period, while the levels of thiobarbituric acid-reactive substances (TBARS), as serum indicator of lipid peroxidation, were reduced significantly. These results indicate a positive impact of regular chokeberry juice consumption on cellular oxidative damage and suggest its putative role in the protection against oxidative stress.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Functional Foods",
title = "Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women",
pages = "97-89",
volume = "9",
doi = "10.1016/j.jff.2014.04.019"
}

Kardum, N. Đ., Takić, Marija., Savikin, K., Zec, M. M., Zdunić, G., Spasić, S.,& Konić-Ristić, A.. (2014). Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women. in Journal of Functional Foods
Elsevier, Amsterdam., 9, 89-97.
https://doi.org/10.1016/j.jff.2014.04.019

Kardum NĐ, Takić M, Savikin K, Zec MM, Zdunić G, Spasić S, Konić-Ristić A. Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women. in Journal of Functional Foods. 2014;9:89-97.
doi:10.1016/j.jff.2014.04.019 .

Kardum, Nevena Đ., Takić, Marija., Savikin, Katarina, Zec, Manja M., Zdunić, Gordana, Spasić, Slavica, Konić-Ristić, Aleksandra, "Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women" in Journal of Functional Foods, 9 (2014):89-97,
https://doi.org/10.1016/j.jff.2014.04.019 . .

TY  - JOUR
AU  - Savikin, Katarina
AU  - Menković, Nemanja
AU  - Zdunić, Gordana
AU  - Pljevljakusić, Dejan
AU  - Spasić, Slavica
AU  - Kardum, Nevena Đ.
AU  - Konić-Ristić, Aleksandra
PY  - 2014
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/587
AB  - The aim of our study was to investigate possible beneficial effects of organic chokeberry juice (OCJ) consumption in the treatment of cellulite. Twenty-nine women aged 25-48 with a cellulite grade 2 according to the Nurnberger-Muller scale were included. Anthropometric and biochemical parameters were measured. Skin structure was analyzed by ultrasonography. All subjects consumed 100mL of OCJ per day, during 90 days. Measurements of investigated parameters were performed at 0, 45, and 90 days of the study. A marked reduction in the subcutaneous tissue thickness was observed in all subjects, with the average reduction of 1.9mm. The length of subcutaneous tissue fascicles (ScTFL) was reduced in 97% (28 out of 29) of subjects, with the average value of 1.18mm. After 45 days of chokeberry juice consumption, reduction of edema was observed in 55.2% of the subjects with edema at the baseline, while at the endpoint of the study, edemas were not observed in any of the subjects involved in the study. OCJ could have beneficial effects on the cellulite condition, including the length of ScTFL, subcutaneous tissue, and dermis thickness as well as on edema reduction.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Dietary Supplementation with Polyphenol-Rich Chokeberry Juice Improves Skin Morphology in Cellulite
EP  - 587
IS  - 5
SP  - 582
VL  - 17
DO  - 10.1089/jmf.2013.0102
ER  - 

@article{
author = "Savikin, Katarina and Menković, Nemanja and Zdunić, Gordana and Pljevljakusić, Dejan and Spasić, Slavica and Kardum, Nevena Đ. and Konić-Ristić, Aleksandra",
year = "2014",
abstract = "The aim of our study was to investigate possible beneficial effects of organic chokeberry juice (OCJ) consumption in the treatment of cellulite. Twenty-nine women aged 25-48 with a cellulite grade 2 according to the Nurnberger-Muller scale were included. Anthropometric and biochemical parameters were measured. Skin structure was analyzed by ultrasonography. All subjects consumed 100mL of OCJ per day, during 90 days. Measurements of investigated parameters were performed at 0, 45, and 90 days of the study. A marked reduction in the subcutaneous tissue thickness was observed in all subjects, with the average reduction of 1.9mm. The length of subcutaneous tissue fascicles (ScTFL) was reduced in 97% (28 out of 29) of subjects, with the average value of 1.18mm. After 45 days of chokeberry juice consumption, reduction of edema was observed in 55.2% of the subjects with edema at the baseline, while at the endpoint of the study, edemas were not observed in any of the subjects involved in the study. OCJ could have beneficial effects on the cellulite condition, including the length of ScTFL, subcutaneous tissue, and dermis thickness as well as on edema reduction.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Dietary Supplementation with Polyphenol-Rich Chokeberry Juice Improves Skin Morphology in Cellulite",
pages = "587-582",
number = "5",
volume = "17",
doi = "10.1089/jmf.2013.0102"
}

Savikin, K., Menković, N., Zdunić, G., Pljevljakusić, D., Spasić, S., Kardum, N. Đ.,& Konić-Ristić, A.. (2014). Dietary Supplementation with Polyphenol-Rich Chokeberry Juice Improves Skin Morphology in Cellulite. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 17(5), 582-587.
https://doi.org/10.1089/jmf.2013.0102

Savikin K, Menković N, Zdunić G, Pljevljakusić D, Spasić S, Kardum NĐ, Konić-Ristić A. Dietary Supplementation with Polyphenol-Rich Chokeberry Juice Improves Skin Morphology in Cellulite. in Journal of Medicinal Food. 2014;17(5):582-587.
doi:10.1089/jmf.2013.0102 .

Savikin, Katarina, Menković, Nemanja, Zdunić, Gordana, Pljevljakusić, Dejan, Spasić, Slavica, Kardum, Nevena Đ., Konić-Ristić, Aleksandra, "Dietary Supplementation with Polyphenol-Rich Chokeberry Juice Improves Skin Morphology in Cellulite" in Journal of Medicinal Food, 17, no. 5 (2014):582-587,
https://doi.org/10.1089/jmf.2013.0102 . .

TY  - JOUR
AU  - Kardum, Nevena Đ.
AU  - Konić-Ristić, Aleksandra
AU  - Savikin, Katarina
AU  - Spasić, Slavica
AU  - Stefanović, Aleksandra
AU  - Ivanišević, Jasmina
AU  - Miljković, Milica
PY  - 2014
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/568
AB  - Berry fruits are a rich source of polyphenols, especially anthocyanins: well-known potent anti-oxidant phytochemicals. The purpose of this study was to evaluate beneficial effects of long-term consumption of polyphenol-rich organic chokeberry juice on different markers of antioxidant/pro-oxidant status in healthy female volunteers. Twenty-nine women, aged 25-49, were included in the study. Serological markers of oxidative stress and antioxidant defence, blood pressure, routine biochemical, and anthropometric parameters were analyzed at baseline and after twelve weeks of regular chokeberry juice consumption. Significant decrease in thiobarbituric acid-reactive substances level (TBARS; P  lt  .001) and pro-oxidant-antioxidant balance (PAB; P  lt  .05), as well as increase in paroxonase-1 activity toward diazoxon (P  lt  .01) were found. Total oxidative status and sulphydryl groups levels were not significantly influenced by the intervention. Anthropometric, biochemical parameters, and blood pressure values were within the referent values for all subjects and were not influenced by the chokeberry juice consumption. However, we found positive correlation between age, body mass index, waist circumference, body fat percent, blood pressure, and analyzed marker of lipid peroxidation, which was influenced by the consumption. In conclusion, the fine modulation of several antioxidant/pro-oxidant status biomarkers observed in healthy subjects indicates putative prophylactic effects of polyphenol-rich chokeberry juice and supports its importance as part of an optimal diet.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects
EP  - 874
IS  - 8
SP  - 869
VL  - 17
DO  - 10.1089/jmf.2013.0135
ER  - 

@article{
author = "Kardum, Nevena Đ. and Konić-Ristić, Aleksandra and Savikin, Katarina and Spasić, Slavica and Stefanović, Aleksandra and Ivanišević, Jasmina and Miljković, Milica",
year = "2014",
abstract = "Berry fruits are a rich source of polyphenols, especially anthocyanins: well-known potent anti-oxidant phytochemicals. The purpose of this study was to evaluate beneficial effects of long-term consumption of polyphenol-rich organic chokeberry juice on different markers of antioxidant/pro-oxidant status in healthy female volunteers. Twenty-nine women, aged 25-49, were included in the study. Serological markers of oxidative stress and antioxidant defence, blood pressure, routine biochemical, and anthropometric parameters were analyzed at baseline and after twelve weeks of regular chokeberry juice consumption. Significant decrease in thiobarbituric acid-reactive substances level (TBARS; P  lt  .001) and pro-oxidant-antioxidant balance (PAB; P  lt  .05), as well as increase in paroxonase-1 activity toward diazoxon (P  lt  .01) were found. Total oxidative status and sulphydryl groups levels were not significantly influenced by the intervention. Anthropometric, biochemical parameters, and blood pressure values were within the referent values for all subjects and were not influenced by the chokeberry juice consumption. However, we found positive correlation between age, body mass index, waist circumference, body fat percent, blood pressure, and analyzed marker of lipid peroxidation, which was influenced by the consumption. In conclusion, the fine modulation of several antioxidant/pro-oxidant status biomarkers observed in healthy subjects indicates putative prophylactic effects of polyphenol-rich chokeberry juice and supports its importance as part of an optimal diet.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects",
pages = "874-869",
number = "8",
volume = "17",
doi = "10.1089/jmf.2013.0135"
}

Kardum, N. Đ., Konić-Ristić, A., Savikin, K., Spasić, S., Stefanović, A., Ivanišević, J.,& Miljković, M.. (2014). Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 17(8), 869-874.
https://doi.org/10.1089/jmf.2013.0135

Kardum NĐ, Konić-Ristić A, Savikin K, Spasić S, Stefanović A, Ivanišević J, Miljković M. Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects. in Journal of Medicinal Food. 2014;17(8):869-874.
doi:10.1089/jmf.2013.0135 .

Kardum, Nevena Đ., Konić-Ristić, Aleksandra, Savikin, Katarina, Spasić, Slavica, Stefanović, Aleksandra, Ivanišević, Jasmina, Miljković, Milica, "Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects" in Journal of Medicinal Food, 17, no. 8 (2014):869-874,
https://doi.org/10.1089/jmf.2013.0135 . .