TY  - JOUR
AU  - Ćujić, Nada
AU  - Savikin, Katarina
AU  - Miloradović, Zoran
AU  - Ivanov, Milan
AU  - Vajić, Una Jovana
AU  - Karanović, Danijela
AU  - Grujić-Milanović, Jelica
AU  - Jovović, Đurđica
AU  - Mihailović-Stanojević, Nevena
PY  - 2018
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/894
AB  - The potential beneficial effects of chronic consumption of dried chokeberry fruit extract (DCE) were evaluated in the present in vivo study. The study concentrates on haemodynamic parameters, lipid profile and oxidative stress in spontaneously hypertensive rats. DCE was characterized by HPLC/DAD method and individual anthocyanins, phenolic acids, and flavonoids were determined. Four week administration of DCE, rich in polyphenols, especially anthocyanins, significantly reduced systolic (P  lt  0.05), pulse pressure (P  lt  0.05) compared to control group, probably via significantly increased diuresis (P  lt  0.05). Significant decrease of plasma and erythrocytes TBARS was also found in the treated group. DCE consumption reduced lipid peroxidation through improving plasma FRAP reducing (P  lt  0.01). The activity of SOD in the treated group had been significantly lower (P  lt  0.01) compared to the control group. These results suggest that DCE could exert beneficial effects on cardiovascular health and has a potential as a nutritional supplement in arterial hypertension.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Functional Foods
T1  - Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats
EP  - 339
SP  - 330
VL  - 44
DO  - 10.1016/j.jff.2018.02.027
ER  - 

@article{
author = "Ćujić, Nada and Savikin, Katarina and Miloradović, Zoran and Ivanov, Milan and Vajić, Una Jovana and Karanović, Danijela and Grujić-Milanović, Jelica and Jovović, Đurđica and Mihailović-Stanojević, Nevena",
year = "2018",
abstract = "The potential beneficial effects of chronic consumption of dried chokeberry fruit extract (DCE) were evaluated in the present in vivo study. The study concentrates on haemodynamic parameters, lipid profile and oxidative stress in spontaneously hypertensive rats. DCE was characterized by HPLC/DAD method and individual anthocyanins, phenolic acids, and flavonoids were determined. Four week administration of DCE, rich in polyphenols, especially anthocyanins, significantly reduced systolic (P  lt  0.05), pulse pressure (P  lt  0.05) compared to control group, probably via significantly increased diuresis (P  lt  0.05). Significant decrease of plasma and erythrocytes TBARS was also found in the treated group. DCE consumption reduced lipid peroxidation through improving plasma FRAP reducing (P  lt  0.01). The activity of SOD in the treated group had been significantly lower (P  lt  0.01) compared to the control group. These results suggest that DCE could exert beneficial effects on cardiovascular health and has a potential as a nutritional supplement in arterial hypertension.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Functional Foods",
title = "Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats",
pages = "339-330",
volume = "44",
doi = "10.1016/j.jff.2018.02.027"
}

Ćujić, N., Savikin, K., Miloradović, Z., Ivanov, M., Vajić, U. J., Karanović, D., Grujić-Milanović, J., Jovović, Đ.,& Mihailović-Stanojević, N.. (2018). Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats. in Journal of Functional Foods
Elsevier Science Bv, Amsterdam., 44, 330-339.
https://doi.org/10.1016/j.jff.2018.02.027

Ćujić N, Savikin K, Miloradović Z, Ivanov M, Vajić UJ, Karanović D, Grujić-Milanović J, Jovović Đ, Mihailović-Stanojević N. Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats. in Journal of Functional Foods. 2018;44:330-339.
doi:10.1016/j.jff.2018.02.027 .

Ćujić, Nada, Savikin, Katarina, Miloradović, Zoran, Ivanov, Milan, Vajić, Una Jovana, Karanović, Danijela, Grujić-Milanović, Jelica, Jovović, Đurđica, Mihailović-Stanojević, Nevena, "Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats" in Journal of Functional Foods, 44 (2018):330-339,
https://doi.org/10.1016/j.jff.2018.02.027 . .