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Interplay between stress and cancer—A focus on inflammation
(Frontiers Media S.A., 2023)
Stress is an integral part of life. While acute responses to stress are generally regarded as beneficial in dealing with immediate threats, chronic exposure to threatening stimuli exerts deleterious effects and can be ...
Dietary patterns, caloric restrictions for management of cardiovascular disease and cancer; a brief review
(IMR Press Limited, 2022)
Cardiovascular disease (CVD) and cancers are overall still identified as the two most prevalent non-communicable diseases globally. Their prevention and potential reversal (in particular CVD risk) was seen effective with ...
The Role of the TGF-beta Coreceptor Endoglin in Cancer
(Hindawi Ltd, London, 2010)
Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-beta) that interacts with type I and type II TGF-beta receptors and modulates TGF-beta signaling. Endoglin is overexpressed in the ...
Targeting Stress Erythropoiesis Pathways in Cancer
(Frontiers Media S.A, 2022)
Cancer-related anemia (CRA) is a common multifactorial disorder that adversely affects the quality of life and overall prognosis in patients with cancer. Safety concerns associated with the most common CRA treatment options, ...
Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
(Pharmaceutics, 2022)
The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene expression due to the abnormal activation of histone ...
Editorial: Regional and molecular fingerprint of adipogenesis in aging and disease
(Frontiers Media S.A., 2023)
Mesenchymal stromal cell engagement in cancer cell epithelial to mesenchymal transition
(Wiley, Hoboken, 2018)
Due to coexistence of stromal and epithelial tumor cells, their dynamic interactions have been widely recognized as significant cellular components to the tumor tissue integrity. Initiation and outcome of epithelial to ...
Detrimental Effect of Various Preparations of the Human Amniotic Membrane Homogenate on the 2D and 3D Bladder Cancer In vitro Models
(Frontiers Media S.A., 2021)
Despite being among the ten most common cancers with high recurrence rates worldwide, there have been no major breakthroughs in the standard treatment options for bladder cancer in recent years. The use of a human amniotic ...
Metabolic Plasticity of Stem Cells and Macrophages in Cancer
(Frontiers Media Sa, Lausanne, 2017)
In addition to providing essential molecules for the overall function of cells, metabolism plays an important role in cell fate and can be affected by microenvironmental stimuli as well as cellular interactions. As a ...
Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules
(Srpsko hemijsko društvo, Beograd, 2015)
New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for their antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. ...