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Transforming growth factor-beta regulation of urokinase type plasminogen system: Mutual interactions and potential combinatory implications in oncotherapies
(Plasminogen Activator: Genetic Factors, Functions & Clinical Applications, 2014)
The urokinase type plasminogen activator (uPA) system comprises uPA, the uPA cell surface receptor (uPAR), plasminogen-plasmin and the uPA inhibitors PAI-1 and 2. This system is involved in the proteolytic degradation and ...
Palmitic acid as a cardiometabolic risk factor
(Palmitic Acid: Occurrence, Biochemistry & Health Effects, 2014)
Current dietary recommendations are based on a reduced saturated fatty acid (SFA) consumption to prevent cardiovascular disease (CVD). The role of individual SFA in metabolic disease is not fully understandable. One type ...
Hydatidosis of the central nervous system in central and Eastern Europe
(Hydatidosis of the Central Nervous System: Diagnosis & Treatment, 2014)
Hydatidosis (also known as echinococcosis or hydatid disease) is one of Europe's neglected infections of poverty. Cystic echinococcosis (CE) is endemic in Southwestern and Eastern parts of Europe. Although alveolar ...