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Increase in Frequency of Myeloid-Derived Suppressor Cells in the Bone Marrow of Myeloproliferative Neoplasm: Potential Implications in Myelofibrosis
(Springer Nature, 2023)
The Philadelphia-negative myeloproliferative neoplasms (MPNs), defined as clonal disorders of the hematopoietic stem cells, are characterized by the proliferation of mature myeloid cells in the bone marrow and a chronic ...
Recent advances in and applications of encapsulated microbial and non-microbial active agents in food and beverage manufacture
(Advances in Food Biotechnology, 2015)
Encapsulation is a well-established process that allows formulation of a wide range of active agents within a defined carrier material using various techniques. This chapter describes the general concept and benefits of ...
BMAL1 Regulates Glucokinase Expression Through E-Box Elements In Vitro
(Springer Nature Switzerland, 2023)
The organization of a circadian system includes an endogenous pacemaker system, input pathways for environmental synchronizing (entraining) stimuli, and output pathways through which the clock regulates physiological and ...
Appraisal of the Neuroprotective Effect of Dexmedetomidine: A Meta-Analysis
(Springer Nature, 2023)
Dexmedetomidine is an adrenergic receptor agonist that has been regarded as neuroprotective in several studies without an objective measure to it. Thus, the aim of this meta-analysis was to analyze and quantify the current ...
Effects of near-infrared low-level laser stimulation on neuronal excitability
(Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology & Neuroscience, 2019)
Effects of near-infrared low-level laser (NIR LLL) on brain excitability have been seldom investigated. A few studies carried out so far showed that following several minutes of transcranial NIR LLL illumination, the output ...
Erythrocyte membranes: Unique constituent of biological/hybri drug delivery systems
(Erythrocytes: Structure, Functions & Clinical Aspects, 2019)
For many decades, the red blood cell membranes were in focus of research interest solely as a model system for investigation into the various membrane-related phenomena, composition/organization or membrane transport ...
Hydatidosis of the central nervous system in central and Eastern Europe
(Hydatidosis of the Central Nervous System: Diagnosis & Treatment, 2014)
Hydatidosis (also known as echinococcosis or hydatid disease) is one of Europe's neglected infections of poverty. Cystic echinococcosis (CE) is endemic in Southwestern and Eastern parts of Europe. Although alveolar ...
Eicosapentaenoic acid: The role in malignant diseases
(Eicosapentaenoic Acid: Sources, Health Effects & Role in Disease Prevention, 2012)
A number of epidemiological and experimental evidences have linked polyunsaturated fatty acids (PUFA) of n-3 series to reduced cancer risk. Particularly the long chain n-3 PUFA eicosapentaenoic acid (EPA) and docosahexaenoic ...
Transforming growth factor-beta regulation of urokinase type plasminogen system: Mutual interactions and potential combinatory implications in oncotherapies
(Plasminogen Activator: Genetic Factors, Functions & Clinical Applications, 2014)
The urokinase type plasminogen activator (uPA) system comprises uPA, the uPA cell surface receptor (uPAR), plasminogen-plasmin and the uPA inhibitors PAI-1 and 2. This system is involved in the proteolytic degradation and ...
Effects of Adrenergic Receptor Stimulation on Human Hemostasis: A Systematic Review
(Springer Nature, 2023)
Catecholamine stimulation over adrenergic receptors results in a state of hypercoagulability. Chronic stress involves the release and increase in circulation of catecholamines and other stress related hormones. Numerous ...