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The Role of the TGF-beta Coreceptor Endoglin in Cancer
(Hindawi Ltd, London, 2010)
Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-beta) that interacts with type I and type II TGF-beta receptors and modulates TGF-beta signaling. Endoglin is overexpressed in the ...
TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions
(Portland Press Ltd, London, 2011)
The TGF-beta (transforming growth factor-beta) system signals via protein kinase receptors and Smad mediators to regulate a plethora of biological processes, including morphogenesis, embryonic development, adult stem cell ...
Mesenchymal stromal cell engagement in cancer cell epithelial to mesenchymal transition
(Wiley, Hoboken, 2018)
Due to coexistence of stromal and epithelial tumor cells, their dynamic interactions have been widely recognized as significant cellular components to the tumor tissue integrity. Initiation and outcome of epithelial to ...
Metabolic Plasticity of Stem Cells and Macrophages in Cancer
(Frontiers Media Sa, Lausanne, 2017)
In addition to providing essential molecules for the overall function of cells, metabolism plays an important role in cell fate and can be affected by microenvironmental stimuli as well as cellular interactions. As a ...