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Targeting Stress Erythropoiesis Pathways in Cancer
(Frontiers Media S.A, 2022)
Cancer-related anemia (CRA) is a common multifactorial disorder that adversely affects the quality of life and overall prognosis in patients with cancer. Safety concerns associated with the most common CRA treatment options, ...
Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats
(Public Library Science, San Francisco, 2020)
Renal ischemia/reperfusion injury is a common cause of acute kidney injury (AKI) and hypertension might contribute to the increased incidence of AKI. The purpose of this study was to investigate the effects of single and ...
The Polymorphisms of Genes Encoding Catalytic Antioxidant Proteins Modulate the Susceptibility and Progression of Testicular Germ Cell Tumor
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
The simultaneous analysis of redox biomarkers and polymorphisms encoding for regulatory and catalytic antioxidant proteins was performed in order to evaluate their potential role in the development of testicular germ cell ...
Clinicopathological Relevance of PAX8 Expression Patterns in Acute Kidney Injury and Chronic Kidney Diseases
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Transcription factor PAX8, expressed during embryonic kidney development, has been previously detected in various kidney tumors. In order to investigate expression of PAX8 transcription factor in acute kidney injury (AKI) ...
Region-specific differences of marrow adipogenesis in mesenchymal stromal (stem) cells of human acetabulum and femur: involvement of fatty acid oxidation
(American Society for Bone and Mineral Research, 2023)
Aging and disease-induced adipogenesis in skeletal system has been described as detrimental process for bone tissue metabolism. Dynamic of adipogenic program is controlled by microenvironmental factors and activity of bone ...
An updated pharmacological insight into calotropin as a potential therapeutic agent in cancer
(Frontiers Media S.A., 2023)
Calotropin is a pharmacologically active compound isolated from milkweed plants like Calotropis procera, Calotropis gigantea, and Asclepias currasavica that belong to the Asclepiadaceae family. All of these plants are ...
Community Pharmacists' Attitudes and Professional Practice in Relation to the Patient Safety Incidents
(Assoc Pharmaceutical Teachers India, Bangalore, 2020)
Background: Medicines dispensing is an error-prone activity, therefore potentially jeopardizing patient safety. This study aimed to assess the community pharmacists' attitudes towards the causes of dispensing errors and ...
Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii
(Oxford Univ Press, Oxford, 2002)
The efficacy of atovaquone (ATO) combined with clindamycin (CLI) against Toxoplasma gondii was examined in murine models of infection with a mouse-non-virulent (Me49) strain. Swiss-Webster mice inoculated by mouth with 10 ...
Design, formulation and sensory evaluation of a polyphenol-rich food placebo: an example of aronia juice for food intervention studies
(Taylor & Francis Ltd, Abingdon, 2017)
Products suitable for use as controls in food interventions designed to demonstrate the role of minor components are largely lacking. In the present study, we aimed to develop a formulation to be used as a placebo in a ...
Toxoplasma gondii Infection Induces Lipid Metabolism Alterations in the Murine Host
(Elsevier Sci Ltd, Oxford, 2008)