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Evidence for host genetic regulation of altered lipid metabolism in experimental toxoplasmosis supported with gene data mining results
(Public Library Science, San Francisco, 2017)
Toxoplasma gondii is one of the most successful parasites on Earth, infecting a wide array of mammals including one third of the global human population. The obligate intracellular protozoon is not capable of synthesizing ...
Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression
(Hindawi Ltd, London, 2015)
Transforming growth factor-beta (TGF-beta) and oxidative stress/ReactiveOxygen Species (ROS) both have pivotal roles in health and disease. In this review we are analyzing the interplay between TGF-beta and ROS in tumorigenesis ...
Angiogenic factors are increased in circulating granulocytes and CD34(+) cells of myeloproliferative neoplasms
(Wiley-Blackwell, Hoboken, 2017)
It has been shown that angiogenesis and inflammation play an important role in development of most hematological malignancies including the myeloproliferative neoplasm (MPN). The aim of this study was to investigate and ...
Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players
(Shanghai Univ Sport, Shanghai, 2017)
Background: Intensive exercise changes physiological need for glucose and several biochemical pathways responsible for its metabolism response. Among them are those which involve insulin, insulin-like growth factor (IGF-1), ...
Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
(Nature Publishing Group, London, 2017)
Chemotherapy in patients with inoperable or advanced breast cancer inevitably results in low-dose exposure of tumor-cell subset and senescence. Metabolically active senescent cells secrete multiple tumor promoting factors ...
Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016
(Hindawi Ltd, London, 2017)
Babesia microti infection changes host spleen architecture and is cleared by a Th1 immune response
(Frontiers in Microbiology, 2018)
Babesia microti is a malaria-like parasite, which infects ~2000 people annually, such that babesiosis is now a notifiable disease in the United States. Immunocompetent individuals often remain asymptomatic and are tested ...
The Acute Effect of Ethanol on Adrenal Cortex in Female Rats-Possible Role of Nitric Oxide
(Oxford Univ Press, Oxford, 2011)
Aims: The present study was designed to investigate a possible role of endogenous nitric oxide (NO) in the adrenal response to an acute alcohol administration in female rats. To this end, N(omega)-nitro-l-arginine-methyl ...
Angiogenic factors expression in bone marrow and peripheral blood of myeloproliferative neoplasms
(Ferrata Storti Foundation, Pavia, 2012)
Glucocorticoid receptor selectively mediates the expansion of erythroid progenitor cells during chronic restraint stress
(Ferrata Storti Foundation, Pavia, 2012)