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New Iron Twist to Chloroquine─Upgrading Antimalarials with Immunomodulatory and Antimicrobial Features
(American Chemical Society, 2023)
Herein, upgraded chloroquine (CQ) derivatives capable of overcoming Plasmodium resistance and, at the same time, suppressing excessive immune response and risk of concurrent bacteremia were developed. Twelve new ferrocene-CQ ...
Clinical characteristics and management of neurocysticercosis patients: a retrospective assessment of case reports from Europe
(Oxford University Press, 2023)
Objectives: Neurocysticercosis (NCC) is a parasitic disease caused by the larval stage of the tapeworm Taenia solium. NCC mainly occurs in Africa, Latin America and South-East Asia and can cause a variety of clinical
si ...
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project
(Elsevier, 2023)
The neglected zoonosis cystic echinococcosis affects mainly pastoral and rural communities in both low-income and upper-middle-income countries. In Europe, it should be regarded as an orphan and rare disease. Although human ...
Transforming growth factor beta 1 (TGF-β1) in COVID-19 patients: relation to platelets and association with the disease outcome
(Springer Nature, 2023)
Transforming growth factor beta (TGF-β) is a ubiquitously distributed cytokine known to contribute to the pathogenesis of numerous pathological processes. The aim of this study was to measure serum concentrations of TGF-β1 ...
Nitric oxide bioavailability and antioxidant defence as therapeutic targets in synergistic model of acute kidney injury and hypertension / Bioraspoloživost azotnog monoksida i antioksidativna odbrana kao ciljevi terapije u udruženom modelu akutne bubrežne slabosti i hipertenzije
(Niš : Punta, 2023)
Hipertenzija, koja se izmedu ostalog karakteriše i deficitom vasodilatatornog azotnog monoksida
(AM), mačajno pogoršava kliničku sliku postishernične akutne bubrežne slabosti (ABS) kod ljudi. Ponovno vraćanje krvi u ...
Olive leaf extract in addition to losartan treatment improves albuminuria and progression of focal segmental glomerulosclerosis in hypertensive rats: the role of Klotho / Ekstrakt lista masline u kombinaciji sa Losartanom ima pozitivan efekat na albuminuriju i progresivnu fokalnu segmentalnu glomerulosklerozu u hipertenzivnih miševa: uloga Klotho
(Niš: Punta, 2023)
Prethodne studije su pokazale da klotho poseduje anti-inflamatornu, antifibrotičku i antioksidativnu ulogu, i da postoji direktna pozitivna korelacija izmedu klotho-a i albuminurije kod nekih animalnih modela hronične ...
Dynamic light scattering analysis of immune complexes in sera of rheumatoid arthritis patients
(Elsevier, 2023)
The size of circulating immune complexes (CICs) in rheumatoid arthritis (RA) could be an emerging criterion in disease diagnosis. This study analyzed size and electrokinetic potential of CICs from RA patients, healthy young ...
Exploring the anticancer potential of thiadiazole derivatives of substituted thiosemicarbazones formed via copper-mediated cyclization
(Wiley-Blackwell, 2023)
A couple of N-(4)-morpholine/pyrrolidine-substituted thiosemicarbazones (TSCs) of fluorene-2-carboxaldehyde (FM and FP), and their corresponding thiadiazoles (TDZs) (CFM and CFP), were synthesized and characterized (elemental ...
BMAL1 Regulates Glucokinase Expression Through E-Box Elements In Vitro
(Springer Nature Switzerland, 2023)
The organization of a circadian system includes an endogenous pacemaker system, input pathways for environmental synchronizing (entraining) stimuli, and output pathways through which the clock regulates physiological and ...