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Aminoquinolines afford resistance to cerebral malaria in susceptible mice
(Elsevier Sci Ltd, Oxford, 2020)
Objectives: Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. Methods: In vitro ...
Computational image analysis reveals the structural complexity ofToxoplasma gondiitissue cysts
(Public Library Science, San Francisco, 2020)
Toxoplasma gondiiis an obligate intracellular parasite infecting up to one third of the human population. The central event in the pathogenesis of toxoplasmosis is the conversion of tachyzoites into encysted bradyzoites. ...