TY  - JOUR
AU  - Veselinović, Aleksandra
AU  - Petrović, Snježana
AU  - Žikić, Vladica
AU  - Subotić, Miško
AU  - Jakovljević, Vladimir
AU  - Jeremić, Nevena
AU  - Vučić, Vesna M.
PY  - 2021
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1161
AB  - Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts and restricted, repetitive patterns of behavior, interests and activities. The maternal status of polyunsaturated fatty acids (PUFA) regulates microglial activity and neuroinflammatory pathways during a child’s brain development. In children with ASD, the metabolism of PUFA is thought to be deficient or abnormal, leading to increased production of proinflammatory cytokines, increased oxidative stress and an imbalance in the formation and action of neurotransmitters. In addition, nutritional deficits in omega-3 PUFA may affect gut microbiota and contribute to ASD by the gut–brain axis. The aim of this study was to review the possible role of neuroinflammation in ASD development and the effect of omega-3 PUFA supplementation in children with ASD. Due to a wide heterogeneity across RCTs, no definitive conclusion about omega-3 PUFA effects in ASD can be drawn. Supplementation with PUFA could be considered as one of the aspects in regulating the biological status of the organism and could provide added value to standard medical and psychological interventions for reducing behavioral deficits.
PB  - MDPI
T2  - Medicina
T1  - Neuroinflammation in Autism and Supplementation Based on Omega-3 Polyunsaturated Fatty Acids: A Narrative Review
IS  - 9
SP  - 893
VL  - 57
DO  - 10.3390/medicina57090893
ER  - 

@article{
author = "Veselinović, Aleksandra and Petrović, Snježana and Žikić, Vladica and Subotić, Miško and Jakovljević, Vladimir and Jeremić, Nevena and Vučić, Vesna M.",
year = "2021",
abstract = "Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts and restricted, repetitive patterns of behavior, interests and activities. The maternal status of polyunsaturated fatty acids (PUFA) regulates microglial activity and neuroinflammatory pathways during a child’s brain development. In children with ASD, the metabolism of PUFA is thought to be deficient or abnormal, leading to increased production of proinflammatory cytokines, increased oxidative stress and an imbalance in the formation and action of neurotransmitters. In addition, nutritional deficits in omega-3 PUFA may affect gut microbiota and contribute to ASD by the gut–brain axis. The aim of this study was to review the possible role of neuroinflammation in ASD development and the effect of omega-3 PUFA supplementation in children with ASD. Due to a wide heterogeneity across RCTs, no definitive conclusion about omega-3 PUFA effects in ASD can be drawn. Supplementation with PUFA could be considered as one of the aspects in regulating the biological status of the organism and could provide added value to standard medical and psychological interventions for reducing behavioral deficits.",
publisher = "MDPI",
journal = "Medicina",
title = "Neuroinflammation in Autism and Supplementation Based on Omega-3 Polyunsaturated Fatty Acids: A Narrative Review",
number = "9",
pages = "893",
volume = "57",
doi = "10.3390/medicina57090893"
}

Veselinović, A., Petrović, S., Žikić, V., Subotić, M., Jakovljević, V., Jeremić, N.,& Vučić, V. M.. (2021). Neuroinflammation in Autism and Supplementation Based on Omega-3 Polyunsaturated Fatty Acids: A Narrative Review. in Medicina
MDPI., 57(9), 893.
https://doi.org/10.3390/medicina57090893

Veselinović A, Petrović S, Žikić V, Subotić M, Jakovljević V, Jeremić N, Vučić VM. Neuroinflammation in Autism and Supplementation Based on Omega-3 Polyunsaturated Fatty Acids: A Narrative Review. in Medicina. 2021;57(9):893.
doi:10.3390/medicina57090893 .

Veselinović, Aleksandra, Petrović, Snježana, Žikić, Vladica, Subotić, Miško, Jakovljević, Vladimir, Jeremić, Nevena, Vučić, Vesna M., "Neuroinflammation in Autism and Supplementation Based on Omega-3 Polyunsaturated Fatty Acids: A Narrative Review" in Medicina, 57, no. 9 (2021):893,
https://doi.org/10.3390/medicina57090893 . .

TY  - JOUR
AU  - Milić, Petar
AU  - Jeremić, Jovana
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Jeremić, Nevena
AU  - Bradić, Jovana
AU  - Nikolić-Turnić, Tamara
AU  - Milosavljević, Isidora
AU  - Bolevich, Sergey
AU  - Bolevich, Stefani
AU  - Labudović-Borović, Milica
AU  - Arsić, Aleksandra
AU  - Mitrović, Miroslav
AU  - Jakovljević, Vladimir
AU  - Vučić, Vesna M.
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/936
AB  - This study investigated different dietary strategies, high-fat (HFd), or standard diet (Sd) alone or in combination with standardized Aronia melanocarpa extract (SAE), as a polyphenol-rich diet, and their effects on lipids and fatty acids (FA) in rats with metabolic syndrome (MetS). Wistar albino rats were randomly divided into two groups: healthy and rats with MetS, and then depending on dietary patterns on six groups: healthy rats fed with Sd, healthy rats fed with Sd and SAE, rats with MetS fed with HFd, rats with MetS fed with HFd and SAE, rats with MetS fed with Sd, and rats with MetS fed with Sd and SAE. 4 weeks later, after an overnight fast (12-14 h), blood for determination of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), index of lipid peroxidation (measured as TBARS), and FA was collected. Increased FA and lipid concentration found in MetS rats were reduced when changing dietary habits from HFd to Sd with or without SAE consumption. Consumption of SAE slightly affects the FA profiles, mostly palmitoleic acid in healthy rats and PUFA in MetS + HFd rats. Nevertheless, in a high-fat diet, SAE supplementation significantly decreases n-6/n-3 ratio, thereby decreasing systemic inflammation. Further researches are warranted to confirm these effects in humans.
PB  - Springer, Dordrecht
T2  - Molecular & Cellular Biochemistry
T1  - Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats
EP  - 150
IS  - 1-2
SP  - 141
VL  - 461
DO  - 10.1007/s11010-019-03597-6
ER  - 

@article{
author = "Milić, Petar and Jeremić, Jovana and Živković, Vladimir and Srejović, Ivan and Jeremić, Nevena and Bradić, Jovana and Nikolić-Turnić, Tamara and Milosavljević, Isidora and Bolevich, Sergey and Bolevich, Stefani and Labudović-Borović, Milica and Arsić, Aleksandra and Mitrović, Miroslav and Jakovljević, Vladimir and Vučić, Vesna M.",
year = "2019",
abstract = "This study investigated different dietary strategies, high-fat (HFd), or standard diet (Sd) alone or in combination with standardized Aronia melanocarpa extract (SAE), as a polyphenol-rich diet, and their effects on lipids and fatty acids (FA) in rats with metabolic syndrome (MetS). Wistar albino rats were randomly divided into two groups: healthy and rats with MetS, and then depending on dietary patterns on six groups: healthy rats fed with Sd, healthy rats fed with Sd and SAE, rats with MetS fed with HFd, rats with MetS fed with HFd and SAE, rats with MetS fed with Sd, and rats with MetS fed with Sd and SAE. 4 weeks later, after an overnight fast (12-14 h), blood for determination of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), index of lipid peroxidation (measured as TBARS), and FA was collected. Increased FA and lipid concentration found in MetS rats were reduced when changing dietary habits from HFd to Sd with or without SAE consumption. Consumption of SAE slightly affects the FA profiles, mostly palmitoleic acid in healthy rats and PUFA in MetS + HFd rats. Nevertheless, in a high-fat diet, SAE supplementation significantly decreases n-6/n-3 ratio, thereby decreasing systemic inflammation. Further researches are warranted to confirm these effects in humans.",
publisher = "Springer, Dordrecht",
journal = "Molecular & Cellular Biochemistry",
title = "Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats",
pages = "150-141",
number = "1-2",
volume = "461",
doi = "10.1007/s11010-019-03597-6"
}

Milić, P., Jeremić, J., Živković, V., Srejović, I., Jeremić, N., Bradić, J., Nikolić-Turnić, T., Milosavljević, I., Bolevich, S., Bolevich, S., Labudović-Borović, M., Arsić, A., Mitrović, M., Jakovljević, V.,& Vučić, V. M.. (2019). Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats. in Molecular & Cellular Biochemistry
Springer, Dordrecht., 461(1-2), 141-150.
https://doi.org/10.1007/s11010-019-03597-6

Milić P, Jeremić J, Živković V, Srejović I, Jeremić N, Bradić J, Nikolić-Turnić T, Milosavljević I, Bolevich S, Bolevich S, Labudović-Borović M, Arsić A, Mitrović M, Jakovljević V, Vučić VM. Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats. in Molecular & Cellular Biochemistry. 2019;461(1-2):141-150.
doi:10.1007/s11010-019-03597-6 .

Milić, Petar, Jeremić, Jovana, Živković, Vladimir, Srejović, Ivan, Jeremić, Nevena, Bradić, Jovana, Nikolić-Turnić, Tamara, Milosavljević, Isidora, Bolevich, Sergey, Bolevich, Stefani, Labudović-Borović, Milica, Arsić, Aleksandra, Mitrović, Miroslav, Jakovljević, Vladimir, Vučić, Vesna M., "Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats" in Molecular & Cellular Biochemistry, 461, no. 1-2 (2019):141-150,
https://doi.org/10.1007/s11010-019-03597-6 . .

TY  - JOUR
AU  - Jakovljević, Vladimir
AU  - Milić, Petar
AU  - Bradić, Jovana
AU  - Jeremić, Jovana
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Nikolić-Turnić, Tamara
AU  - Milosavljević, Isidora
AU  - Jeremić, Nevena
AU  - Bolevich, Sergey
AU  - Labudović-Borović, Milica
AU  - Mitrović, Miroslav
AU  - Vučić, Vesna M.
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/949
AB  - The aim of our study was to examine the effects of different dietary strategies, high-fat (HFd) or standard diet (Sd) alone or in combination with standardized oral supplementation (0.45 mL/kg/day) of Aronia melanocarpa extract (SAE) in rats with metabolic syndrome (MetS). SAE is an official product of pharmaceutical company Pharmanova (Belgrade, Serbia); however, the procedure for extraction was done by EU-Chem company (Belgrade, Serbia). Rats were divided randomly into six groups: control with Sd, control with Sd and SAE, MetS with HFd, MetS with HFd and SAE, MetS with Sd and MetS with Sd and SAE during 4 weeks. At the end of the 4-week protocol, cardiac function and liver morphology were assessed, while in the blood samples glucose, insulin, iron levels and systemic redox state were determined. Our results demonstrated that SAE had the ability to lower blood pressure and exert benefits on in vivo and ex vivo heart function. Moreover, SAE improved glucose tolerance, attenuated pathological liver alterations and oxidative stress present in MetS. Obtained beneficial effects of SAE were more prominent in combination with changing dietary habits. Promising potential of SAE supplementation alone or in combination with different dietary protocols in triggering cardioprotection should be further examined in future.
PB  - MDPI, Basel
T2  - International Journal of Molecular Sciences
T1  - Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model
IS  - 1
VL  - 20
DO  - 10.3390/ijms20010006
ER  - 

@article{
author = "Jakovljević, Vladimir and Milić, Petar and Bradić, Jovana and Jeremić, Jovana and Živković, Vladimir and Srejović, Ivan and Nikolić-Turnić, Tamara and Milosavljević, Isidora and Jeremić, Nevena and Bolevich, Sergey and Labudović-Borović, Milica and Mitrović, Miroslav and Vučić, Vesna M.",
year = "2019",
abstract = "The aim of our study was to examine the effects of different dietary strategies, high-fat (HFd) or standard diet (Sd) alone or in combination with standardized oral supplementation (0.45 mL/kg/day) of Aronia melanocarpa extract (SAE) in rats with metabolic syndrome (MetS). SAE is an official product of pharmaceutical company Pharmanova (Belgrade, Serbia); however, the procedure for extraction was done by EU-Chem company (Belgrade, Serbia). Rats were divided randomly into six groups: control with Sd, control with Sd and SAE, MetS with HFd, MetS with HFd and SAE, MetS with Sd and MetS with Sd and SAE during 4 weeks. At the end of the 4-week protocol, cardiac function and liver morphology were assessed, while in the blood samples glucose, insulin, iron levels and systemic redox state were determined. Our results demonstrated that SAE had the ability to lower blood pressure and exert benefits on in vivo and ex vivo heart function. Moreover, SAE improved glucose tolerance, attenuated pathological liver alterations and oxidative stress present in MetS. Obtained beneficial effects of SAE were more prominent in combination with changing dietary habits. Promising potential of SAE supplementation alone or in combination with different dietary protocols in triggering cardioprotection should be further examined in future.",
publisher = "MDPI, Basel",
journal = "International Journal of Molecular Sciences",
title = "Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model",
number = "1",
volume = "20",
doi = "10.3390/ijms20010006"
}

Jakovljević, V., Milić, P., Bradić, J., Jeremić, J., Živković, V., Srejović, I., Nikolić-Turnić, T., Milosavljević, I., Jeremić, N., Bolevich, S., Labudović-Borović, M., Mitrović, M.,& Vučić, V. M.. (2019). Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model. in International Journal of Molecular Sciences
MDPI, Basel., 20(1).
https://doi.org/10.3390/ijms20010006

Jakovljević V, Milić P, Bradić J, Jeremić J, Živković V, Srejović I, Nikolić-Turnić T, Milosavljević I, Jeremić N, Bolevich S, Labudović-Borović M, Mitrović M, Vučić VM. Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model. in International Journal of Molecular Sciences. 2019;20(1).
doi:10.3390/ijms20010006 .

Jakovljević, Vladimir, Milić, Petar, Bradić, Jovana, Jeremić, Jovana, Živković, Vladimir, Srejović, Ivan, Nikolić-Turnić, Tamara, Milosavljević, Isidora, Jeremić, Nevena, Bolevich, Sergey, Labudović-Borović, Milica, Mitrović, Miroslav, Vučić, Vesna M., "Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model" in International Journal of Molecular Sciences, 20, no. 1 (2019),
https://doi.org/10.3390/ijms20010006 . .

TY  - JOUR
AU  - Vasiljević, Dragan
AU  - Veselinović, Mirjana
AU  - Jovanović, Maja
AU  - Jeremić, Nevena
AU  - Arsić, Aleksandra
AU  - Vučić, Vesna M.
AU  - Lucic-Tomić, Aleksandra
AU  - Živanović, Sandra
AU  - Đurić, Dragan
AU  - Jakovljević, Vladimir
PY  - 2016
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/746
AB  - Rheumatoid arthritis is a chronic inflammatory disease. Reactive oxygen species have been considered as aggravating factors for autoimmune diseases. Fatty acids had been linked in reduction of various diseases by augment of their antioxidant potential and antiinflammatory mechanisms. The aim of this study was to assess the oxidative status in patients with rheumatoid arthritis who used concentrated fish oil only or concentrated fish oil in combination with evening primrose oil in a period of 3 months. Subjects were divided into three groups. The group I consists of patients who had been taking only their regular rheumatologic therapy; group II, patients who had been taking concentrated fish oil; and group III, patients who had been taking concentrated fish oil and evening primrose oil. Peripheral blood samples were used for all the assays. We assessed the following oxidative stress markers: index of lipid peroxidation (thiobarbituric acid-reactive substances (TBARS)), hydrogen peroxide (H2O2), superoxide anion radical (O-2 (-)), nitric oxide (NO), superoxide dismutase activity (SOD), catalase activity (CAT), and glutathione levels (GSH) in erythrocytes. There were no statistically significant changes for any of the oxidative stress parameters in group I. In group II, levels of TBARS, NO2 (-), and GSH were increased, while levels of H2O2 decreased. Increased values of TBARS, NO2 (-), and SOD were found in group III. Our findings indicate that intakes of fish oil and evening primrose oil may be of importance in mitigation of inflammation, disease activity, and oxidative stress biomarkers, through increased activities of antioxidant enzymes.
PB  - Springer London Ltd, London
T2  - Clinical Rheumatology
T1  - Evaluation of the effects of different supplementation on oxidative status in patients with rheumatoid arthritis
EP  - 1915
IS  - 8
SP  - 1909
VL  - 35
DO  - 10.1007/s10067-016-3168-2
ER  - 

@article{
author = "Vasiljević, Dragan and Veselinović, Mirjana and Jovanović, Maja and Jeremić, Nevena and Arsić, Aleksandra and Vučić, Vesna M. and Lucic-Tomić, Aleksandra and Živanović, Sandra and Đurić, Dragan and Jakovljević, Vladimir",
year = "2016",
abstract = "Rheumatoid arthritis is a chronic inflammatory disease. Reactive oxygen species have been considered as aggravating factors for autoimmune diseases. Fatty acids had been linked in reduction of various diseases by augment of their antioxidant potential and antiinflammatory mechanisms. The aim of this study was to assess the oxidative status in patients with rheumatoid arthritis who used concentrated fish oil only or concentrated fish oil in combination with evening primrose oil in a period of 3 months. Subjects were divided into three groups. The group I consists of patients who had been taking only their regular rheumatologic therapy; group II, patients who had been taking concentrated fish oil; and group III, patients who had been taking concentrated fish oil and evening primrose oil. Peripheral blood samples were used for all the assays. We assessed the following oxidative stress markers: index of lipid peroxidation (thiobarbituric acid-reactive substances (TBARS)), hydrogen peroxide (H2O2), superoxide anion radical (O-2 (-)), nitric oxide (NO), superoxide dismutase activity (SOD), catalase activity (CAT), and glutathione levels (GSH) in erythrocytes. There were no statistically significant changes for any of the oxidative stress parameters in group I. In group II, levels of TBARS, NO2 (-), and GSH were increased, while levels of H2O2 decreased. Increased values of TBARS, NO2 (-), and SOD were found in group III. Our findings indicate that intakes of fish oil and evening primrose oil may be of importance in mitigation of inflammation, disease activity, and oxidative stress biomarkers, through increased activities of antioxidant enzymes.",
publisher = "Springer London Ltd, London",
journal = "Clinical Rheumatology",
title = "Evaluation of the effects of different supplementation on oxidative status in patients with rheumatoid arthritis",
pages = "1915-1909",
number = "8",
volume = "35",
doi = "10.1007/s10067-016-3168-2"
}

Vasiljević, D., Veselinović, M., Jovanović, M., Jeremić, N., Arsić, A., Vučić, V. M., Lucic-Tomić, A., Živanović, S., Đurić, D.,& Jakovljević, V.. (2016). Evaluation of the effects of different supplementation on oxidative status in patients with rheumatoid arthritis. in Clinical Rheumatology
Springer London Ltd, London., 35(8), 1909-1915.
https://doi.org/10.1007/s10067-016-3168-2

Vasiljević D, Veselinović M, Jovanović M, Jeremić N, Arsić A, Vučić VM, Lucic-Tomić A, Živanović S, Đurić D, Jakovljević V. Evaluation of the effects of different supplementation on oxidative status in patients with rheumatoid arthritis. in Clinical Rheumatology. 2016;35(8):1909-1915.
doi:10.1007/s10067-016-3168-2 .

Vasiljević, Dragan, Veselinović, Mirjana, Jovanović, Maja, Jeremić, Nevena, Arsić, Aleksandra, Vučić, Vesna M., Lucic-Tomić, Aleksandra, Živanović, Sandra, Đurić, Dragan, Jakovljević, Vladimir, "Evaluation of the effects of different supplementation on oxidative status in patients with rheumatoid arthritis" in Clinical Rheumatology, 35, no. 8 (2016):1909-1915,
https://doi.org/10.1007/s10067-016-3168-2 . .

TY  - JOUR
AU  - Arsić, Aleksandra
AU  - Vučić, Vesna M.
AU  - Glibetić, Marija
AU  - Popović, Tamara B.
AU  - Debeljak-Martačić, Jasmina
AU  - Čubrilo, Dejan
AU  - Ahmetović, Zlatko
AU  - Perić, Dusan
AU  - Borozan, Sunčica
AU  - Đurić, Dragan
AU  - Barudzić, Nevena
AU  - Jakovljević, Vladimir
PY  - 2016
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/721
AB  - BACKGROUND: The aim of the present study was to analyze changes in redox balance throughout parameters of oxidative stress and activities of antioxidant enzymes in elite female water polo (N.=15) and football players (N.=19) aged between 20 and 23. Fourteen age-matched sedentary women were also included in the study. METHODS: Blood sampling was performed to measure levels of lipid peroxidation (MDA), total antioxidant status (TAS), superoxide anion radical (OD, hydrogen peroxide (H2O2), reduced glutathione (GSH), oxidized glutathione (GSSG), nitrites, superoxide dismutase activity (SOD), catalase activity (CAT) and glutathione-peroxidase activity (GPx). RESULTS: Levels of MDA, TAS, GSSG and H2O2 were significantly higher in athletes than in the control women. Football players had higher levels of O-2(-) than the other two groups. Activity of SOD was higher in water polo players when compared with the football and control groups, CAT was increased in all athletes, while GPx did not differ among groups. CONCLUSIONS: Therefore, prolonged intensive training markedly increases oxidative stress in women, which depends on the type of sport. Lower concentration of O-2(-) and increased activity of SOD in water polo players compared to football players suggest that mechanisms of adaptation of antioxidative defense are related to the type of exercise.
PB  - Edizioni Minerva Medica, Turin
T2  - Journal of Sports Medicine & Physical Fitness
T1  - Redox balance in elite female athletes: differences based on sport types
EP  - 8
IS  - 1-2
SP  - 1
VL  - 56
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1427
ER  - 

@article{
author = "Arsić, Aleksandra and Vučić, Vesna M. and Glibetić, Marija and Popović, Tamara B. and Debeljak-Martačić, Jasmina and Čubrilo, Dejan and Ahmetović, Zlatko and Perić, Dusan and Borozan, Sunčica and Đurić, Dragan and Barudzić, Nevena and Jakovljević, Vladimir",
year = "2016",
abstract = "BACKGROUND: The aim of the present study was to analyze changes in redox balance throughout parameters of oxidative stress and activities of antioxidant enzymes in elite female water polo (N.=15) and football players (N.=19) aged between 20 and 23. Fourteen age-matched sedentary women were also included in the study. METHODS: Blood sampling was performed to measure levels of lipid peroxidation (MDA), total antioxidant status (TAS), superoxide anion radical (OD, hydrogen peroxide (H2O2), reduced glutathione (GSH), oxidized glutathione (GSSG), nitrites, superoxide dismutase activity (SOD), catalase activity (CAT) and glutathione-peroxidase activity (GPx). RESULTS: Levels of MDA, TAS, GSSG and H2O2 were significantly higher in athletes than in the control women. Football players had higher levels of O-2(-) than the other two groups. Activity of SOD was higher in water polo players when compared with the football and control groups, CAT was increased in all athletes, while GPx did not differ among groups. CONCLUSIONS: Therefore, prolonged intensive training markedly increases oxidative stress in women, which depends on the type of sport. Lower concentration of O-2(-) and increased activity of SOD in water polo players compared to football players suggest that mechanisms of adaptation of antioxidative defense are related to the type of exercise.",
publisher = "Edizioni Minerva Medica, Turin",
journal = "Journal of Sports Medicine & Physical Fitness",
title = "Redox balance in elite female athletes: differences based on sport types",
pages = "8-1",
number = "1-2",
volume = "56",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1427"
}

Arsić, A., Vučić, V. M., Glibetić, M., Popović, T. B., Debeljak-Martačić, J., Čubrilo, D., Ahmetović, Z., Perić, D., Borozan, S., Đurić, D., Barudzić, N.,& Jakovljević, V.. (2016). Redox balance in elite female athletes: differences based on sport types. in Journal of Sports Medicine & Physical Fitness
Edizioni Minerva Medica, Turin., 56(1-2), 1-8.
https://hdl.handle.net/21.15107/rcub_veterinar_1427

Arsić A, Vučić VM, Glibetić M, Popović TB, Debeljak-Martačić J, Čubrilo D, Ahmetović Z, Perić D, Borozan S, Đurić D, Barudzić N, Jakovljević V. Redox balance in elite female athletes: differences based on sport types. in Journal of Sports Medicine & Physical Fitness. 2016;56(1-2):1-8.
https://hdl.handle.net/21.15107/rcub_veterinar_1427 .

Arsić, Aleksandra, Vučić, Vesna M., Glibetić, Marija, Popović, Tamara B., Debeljak-Martačić, Jasmina, Čubrilo, Dejan, Ahmetović, Zlatko, Perić, Dusan, Borozan, Sunčica, Đurić, Dragan, Barudzić, Nevena, Jakovljević, Vladimir, "Redox balance in elite female athletes: differences based on sport types" in Journal of Sports Medicine & Physical Fitness, 56, no. 1-2 (2016):1-8,
https://hdl.handle.net/21.15107/rcub_veterinar_1427 .

TY  - JOUR
AU  - Radoman, Kristina
AU  - Vučić, Vesna M.
AU  - Arsić, Aleksandra
AU  - Čubrilo, Dejan
AU  - Jeremić, Nevena
AU  - Jeremić, Jovana
AU  - Jakovljević, Vladimir
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/610
AB  - Considering the limited knowledge regarding the effects of n-3 and n-6 PUFAs on the inflammatory response during physical activity, we aimed to evaluate the level of pro- and anti-inflammatory cytokines in young soccer players before and after a maximal physical load test at the beginning and end of a two-month training process. The study included 75 young footballers from Football School 'Kragujevac,' who were followed during the two-month training programme. The subjects were divided into the following groups: 1) control group (consumed a standard diet); 2) group that consumed fish oil (2500 mg of n-3 PUFAs per day); 3) group that consumed nutritional sunflower oil (2500 mg of n-6 PUFAs daily). The maximal progressive exercise test was performed using a treadmill belt. Venous blood samples were drawn 4 times for the determination of cytokine levels (IL-6 and TNF-α): before and after the exercise load test before the two-month training programme (initial measurement) and immediately before and after the exercise load test after the two-month training programme (control measurement). Supplementation with fish oil (n-3) has been associated with reduced levels of IL-6 compared with the initial values. After an acute bout of exercise, n-3 PUFAs did not show a significant effect on inflammatory marker dynamics, whereas n-6 PUFAs slightly stimulated the production of TNF-α.
AB  - S'obzirom na ograničeno znanje o efektima polinezasićenih masnih kiselina (n-3 i n-6 PUFA-Polyunsaturated Fatty Acids), cilj ovog istraživanja bio je da se procene vrednosti pro- i antiinflamatornih medijatora u miru i nakon maksimalnog testa opterećenja pre i nakon dvomesečnog trenažnog programa. U studiji je učestvovalo 75 mladih fudbalera omladinske fudbalske škole 'Kragujevac', starosti od 18 - 19 godina, koji su bili praćeni tokom dva meseca. Oni su bili podeljeni u tri grupe: 1. kontrolna grupa (standardna ishrana), 2. grupa koja je konzumirala riblje ulje (2500mg n-3 PUFA dnevno), 3. grupa koja je konzumirala suncokretovo ulje (2500mg n-6 PUFA dnevno). Venski uzorci krvi za određivanje nivoa citokina (IL-6, TNF- α) uzimani su 4 puta: u miru i nakon testa opterećenja, pre i posle dvomesečnog trenažnog programa. Svakodnevna suplementacija ribljim uljem povezana je sa smanjenim vrednostima IL-6 u odnosu na njegove početne vrednosti. Upotreba različitih vrsta polinezasiđenih masnih kiselina nije bitnije uticala na proizvodnju citokina, neposredno nakon akutnog nastupa sportske aktivnosti (testa opterećenja).
PB  - Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac
T2  - Serbian Journal of Experimental & Clinical Research
T1  - Effects of different PUFA supplementation on inflammatory response markers in young soccer players
T1  - Evaluacija efekata različitih rezima ishrane na inflamatorni odgovor kod mladih fudbalera
EP  - 311
IS  - 4
SP  - 305
VL  - 16
DO  - 10.1515/SJECR-2015-0055
ER  - 

@article{
author = "Radoman, Kristina and Vučić, Vesna M. and Arsić, Aleksandra and Čubrilo, Dejan and Jeremić, Nevena and Jeremić, Jovana and Jakovljević, Vladimir",
year = "2015",
abstract = "Considering the limited knowledge regarding the effects of n-3 and n-6 PUFAs on the inflammatory response during physical activity, we aimed to evaluate the level of pro- and anti-inflammatory cytokines in young soccer players before and after a maximal physical load test at the beginning and end of a two-month training process. The study included 75 young footballers from Football School 'Kragujevac,' who were followed during the two-month training programme. The subjects were divided into the following groups: 1) control group (consumed a standard diet); 2) group that consumed fish oil (2500 mg of n-3 PUFAs per day); 3) group that consumed nutritional sunflower oil (2500 mg of n-6 PUFAs daily). The maximal progressive exercise test was performed using a treadmill belt. Venous blood samples were drawn 4 times for the determination of cytokine levels (IL-6 and TNF-α): before and after the exercise load test before the two-month training programme (initial measurement) and immediately before and after the exercise load test after the two-month training programme (control measurement). Supplementation with fish oil (n-3) has been associated with reduced levels of IL-6 compared with the initial values. After an acute bout of exercise, n-3 PUFAs did not show a significant effect on inflammatory marker dynamics, whereas n-6 PUFAs slightly stimulated the production of TNF-α., S'obzirom na ograničeno znanje o efektima polinezasićenih masnih kiselina (n-3 i n-6 PUFA-Polyunsaturated Fatty Acids), cilj ovog istraživanja bio je da se procene vrednosti pro- i antiinflamatornih medijatora u miru i nakon maksimalnog testa opterećenja pre i nakon dvomesečnog trenažnog programa. U studiji je učestvovalo 75 mladih fudbalera omladinske fudbalske škole 'Kragujevac', starosti od 18 - 19 godina, koji su bili praćeni tokom dva meseca. Oni su bili podeljeni u tri grupe: 1. kontrolna grupa (standardna ishrana), 2. grupa koja je konzumirala riblje ulje (2500mg n-3 PUFA dnevno), 3. grupa koja je konzumirala suncokretovo ulje (2500mg n-6 PUFA dnevno). Venski uzorci krvi za određivanje nivoa citokina (IL-6, TNF- α) uzimani su 4 puta: u miru i nakon testa opterećenja, pre i posle dvomesečnog trenažnog programa. Svakodnevna suplementacija ribljim uljem povezana je sa smanjenim vrednostima IL-6 u odnosu na njegove početne vrednosti. Upotreba različitih vrsta polinezasiđenih masnih kiselina nije bitnije uticala na proizvodnju citokina, neposredno nakon akutnog nastupa sportske aktivnosti (testa opterećenja).",
publisher = "Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac",
journal = "Serbian Journal of Experimental & Clinical Research",
title = "Effects of different PUFA supplementation on inflammatory response markers in young soccer players, Evaluacija efekata različitih rezima ishrane na inflamatorni odgovor kod mladih fudbalera",
pages = "311-305",
number = "4",
volume = "16",
doi = "10.1515/SJECR-2015-0055"
}

Radoman, K., Vučić, V. M., Arsić, A., Čubrilo, D., Jeremić, N., Jeremić, J.,& Jakovljević, V.. (2015). Effects of different PUFA supplementation on inflammatory response markers in young soccer players. in Serbian Journal of Experimental & Clinical Research
Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac., 16(4), 305-311.
https://doi.org/10.1515/SJECR-2015-0055

Radoman K, Vučić VM, Arsić A, Čubrilo D, Jeremić N, Jeremić J, Jakovljević V. Effects of different PUFA supplementation on inflammatory response markers in young soccer players. in Serbian Journal of Experimental & Clinical Research. 2015;16(4):305-311.
doi:10.1515/SJECR-2015-0055 .

Radoman, Kristina, Vučić, Vesna M., Arsić, Aleksandra, Čubrilo, Dejan, Jeremić, Nevena, Jeremić, Jovana, Jakovljević, Vladimir, "Effects of different PUFA supplementation on inflammatory response markers in young soccer players" in Serbian Journal of Experimental & Clinical Research, 16, no. 4 (2015):305-311,
https://doi.org/10.1515/SJECR-2015-0055 . .