TY  - JOUR
AU  - Nikolić-Turnić, Tamara
AU  - Arsić, Aleksandra
AU  - Vučić, Vesna M.
AU  - Petrović, Snježana
AU  - Ristić-Medić, Danijela
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Jeremić, Jovana
AU  - Radonjić, Tanja
AU  - Milosavljević, Isidora
AU  - Bolevich, Sergey
AU  - Bolevich, Stefany
AU  - Đurić, Dragan
AU  - Jakovljević, Vladimir
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/967
PB  - Frontiers Media Sa, Lausanne
T2  - Frontiers in Physiology
T1  - Hydroxymethylglutaryl Coenzyme a Reductase Inhibitors Differentially Modulate Plasma Fatty Acids in Rats With Diet-Induced-Hyperhomocysteinemia: Is omega-3 Fatty Acids Supplementation Necessary?
VL  - 10
DO  - 10.3389/fphys.2019.00892
ER  - 

@article{
author = "Nikolić-Turnić, Tamara and Arsić, Aleksandra and Vučić, Vesna M. and Petrović, Snježana and Ristić-Medić, Danijela and Živković, Vladimir and Srejović, Ivan and Jeremić, Jovana and Radonjić, Tanja and Milosavljević, Isidora and Bolevich, Sergey and Bolevich, Stefany and Đurić, Dragan and Jakovljević, Vladimir",
year = "2019",
publisher = "Frontiers Media Sa, Lausanne",
journal = "Frontiers in Physiology",
title = "Hydroxymethylglutaryl Coenzyme a Reductase Inhibitors Differentially Modulate Plasma Fatty Acids in Rats With Diet-Induced-Hyperhomocysteinemia: Is omega-3 Fatty Acids Supplementation Necessary?",
volume = "10",
doi = "10.3389/fphys.2019.00892"
}

Nikolić-Turnić, T., Arsić, A., Vučić, V. M., Petrović, S., Ristić-Medić, D., Živković, V., Srejović, I., Jeremić, J., Radonjić, T., Milosavljević, I., Bolevich, S., Bolevich, S., Đurić, D.,& Jakovljević, V.. (2019). Hydroxymethylglutaryl Coenzyme a Reductase Inhibitors Differentially Modulate Plasma Fatty Acids in Rats With Diet-Induced-Hyperhomocysteinemia: Is omega-3 Fatty Acids Supplementation Necessary?. in Frontiers in Physiology
Frontiers Media Sa, Lausanne., 10.
https://doi.org/10.3389/fphys.2019.00892

Nikolić-Turnić T, Arsić A, Vučić VM, Petrović S, Ristić-Medić D, Živković V, Srejović I, Jeremić J, Radonjić T, Milosavljević I, Bolevich S, Bolevich S, Đurić D, Jakovljević V. Hydroxymethylglutaryl Coenzyme a Reductase Inhibitors Differentially Modulate Plasma Fatty Acids in Rats With Diet-Induced-Hyperhomocysteinemia: Is omega-3 Fatty Acids Supplementation Necessary?. in Frontiers in Physiology. 2019;10.
doi:10.3389/fphys.2019.00892 .

Nikolić-Turnić, Tamara, Arsić, Aleksandra, Vučić, Vesna M., Petrović, Snježana, Ristić-Medić, Danijela, Živković, Vladimir, Srejović, Ivan, Jeremić, Jovana, Radonjić, Tanja, Milosavljević, Isidora, Bolevich, Sergey, Bolevich, Stefany, Đurić, Dragan, Jakovljević, Vladimir, "Hydroxymethylglutaryl Coenzyme a Reductase Inhibitors Differentially Modulate Plasma Fatty Acids in Rats With Diet-Induced-Hyperhomocysteinemia: Is omega-3 Fatty Acids Supplementation Necessary?" in Frontiers in Physiology, 10 (2019),
https://doi.org/10.3389/fphys.2019.00892 . .

TY  - JOUR
AU  - Milić, Petar
AU  - Jeremić, Jovana
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Jeremić, Nevena
AU  - Bradić, Jovana
AU  - Nikolić-Turnić, Tamara
AU  - Milosavljević, Isidora
AU  - Bolevich, Sergey
AU  - Bolevich, Stefani
AU  - Labudović-Borović, Milica
AU  - Arsić, Aleksandra
AU  - Mitrović, Miroslav
AU  - Jakovljević, Vladimir
AU  - Vučić, Vesna M.
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/936
AB  - This study investigated different dietary strategies, high-fat (HFd), or standard diet (Sd) alone or in combination with standardized Aronia melanocarpa extract (SAE), as a polyphenol-rich diet, and their effects on lipids and fatty acids (FA) in rats with metabolic syndrome (MetS). Wistar albino rats were randomly divided into two groups: healthy and rats with MetS, and then depending on dietary patterns on six groups: healthy rats fed with Sd, healthy rats fed with Sd and SAE, rats with MetS fed with HFd, rats with MetS fed with HFd and SAE, rats with MetS fed with Sd, and rats with MetS fed with Sd and SAE. 4 weeks later, after an overnight fast (12-14 h), blood for determination of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), index of lipid peroxidation (measured as TBARS), and FA was collected. Increased FA and lipid concentration found in MetS rats were reduced when changing dietary habits from HFd to Sd with or without SAE consumption. Consumption of SAE slightly affects the FA profiles, mostly palmitoleic acid in healthy rats and PUFA in MetS + HFd rats. Nevertheless, in a high-fat diet, SAE supplementation significantly decreases n-6/n-3 ratio, thereby decreasing systemic inflammation. Further researches are warranted to confirm these effects in humans.
PB  - Springer, Dordrecht
T2  - Molecular & Cellular Biochemistry
T1  - Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats
EP  - 150
IS  - 1-2
SP  - 141
VL  - 461
DO  - 10.1007/s11010-019-03597-6
ER  - 

@article{
author = "Milić, Petar and Jeremić, Jovana and Živković, Vladimir and Srejović, Ivan and Jeremić, Nevena and Bradić, Jovana and Nikolić-Turnić, Tamara and Milosavljević, Isidora and Bolevich, Sergey and Bolevich, Stefani and Labudović-Borović, Milica and Arsić, Aleksandra and Mitrović, Miroslav and Jakovljević, Vladimir and Vučić, Vesna M.",
year = "2019",
abstract = "This study investigated different dietary strategies, high-fat (HFd), or standard diet (Sd) alone or in combination with standardized Aronia melanocarpa extract (SAE), as a polyphenol-rich diet, and their effects on lipids and fatty acids (FA) in rats with metabolic syndrome (MetS). Wistar albino rats were randomly divided into two groups: healthy and rats with MetS, and then depending on dietary patterns on six groups: healthy rats fed with Sd, healthy rats fed with Sd and SAE, rats with MetS fed with HFd, rats with MetS fed with HFd and SAE, rats with MetS fed with Sd, and rats with MetS fed with Sd and SAE. 4 weeks later, after an overnight fast (12-14 h), blood for determination of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), index of lipid peroxidation (measured as TBARS), and FA was collected. Increased FA and lipid concentration found in MetS rats were reduced when changing dietary habits from HFd to Sd with or without SAE consumption. Consumption of SAE slightly affects the FA profiles, mostly palmitoleic acid in healthy rats and PUFA in MetS + HFd rats. Nevertheless, in a high-fat diet, SAE supplementation significantly decreases n-6/n-3 ratio, thereby decreasing systemic inflammation. Further researches are warranted to confirm these effects in humans.",
publisher = "Springer, Dordrecht",
journal = "Molecular & Cellular Biochemistry",
title = "Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats",
pages = "150-141",
number = "1-2",
volume = "461",
doi = "10.1007/s11010-019-03597-6"
}

Milić, P., Jeremić, J., Živković, V., Srejović, I., Jeremić, N., Bradić, J., Nikolić-Turnić, T., Milosavljević, I., Bolevich, S., Bolevich, S., Labudović-Borović, M., Arsić, A., Mitrović, M., Jakovljević, V.,& Vučić, V. M.. (2019). Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats. in Molecular & Cellular Biochemistry
Springer, Dordrecht., 461(1-2), 141-150.
https://doi.org/10.1007/s11010-019-03597-6

Milić P, Jeremić J, Živković V, Srejović I, Jeremić N, Bradić J, Nikolić-Turnić T, Milosavljević I, Bolevich S, Bolevich S, Labudović-Borović M, Arsić A, Mitrović M, Jakovljević V, Vučić VM. Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats. in Molecular & Cellular Biochemistry. 2019;461(1-2):141-150.
doi:10.1007/s11010-019-03597-6 .

Milić, Petar, Jeremić, Jovana, Živković, Vladimir, Srejović, Ivan, Jeremić, Nevena, Bradić, Jovana, Nikolić-Turnić, Tamara, Milosavljević, Isidora, Bolevich, Sergey, Bolevich, Stefani, Labudović-Borović, Milica, Arsić, Aleksandra, Mitrović, Miroslav, Jakovljević, Vladimir, Vučić, Vesna M., "Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats" in Molecular & Cellular Biochemistry, 461, no. 1-2 (2019):141-150,
https://doi.org/10.1007/s11010-019-03597-6 . .

TY  - JOUR
AU  - Jakovljević, Vladimir
AU  - Milić, Petar
AU  - Bradić, Jovana
AU  - Jeremić, Jovana
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Nikolić-Turnić, Tamara
AU  - Milosavljević, Isidora
AU  - Jeremić, Nevena
AU  - Bolevich, Sergey
AU  - Labudović-Borović, Milica
AU  - Mitrović, Miroslav
AU  - Vučić, Vesna M.
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/949
AB  - The aim of our study was to examine the effects of different dietary strategies, high-fat (HFd) or standard diet (Sd) alone or in combination with standardized oral supplementation (0.45 mL/kg/day) of Aronia melanocarpa extract (SAE) in rats with metabolic syndrome (MetS). SAE is an official product of pharmaceutical company Pharmanova (Belgrade, Serbia); however, the procedure for extraction was done by EU-Chem company (Belgrade, Serbia). Rats were divided randomly into six groups: control with Sd, control with Sd and SAE, MetS with HFd, MetS with HFd and SAE, MetS with Sd and MetS with Sd and SAE during 4 weeks. At the end of the 4-week protocol, cardiac function and liver morphology were assessed, while in the blood samples glucose, insulin, iron levels and systemic redox state were determined. Our results demonstrated that SAE had the ability to lower blood pressure and exert benefits on in vivo and ex vivo heart function. Moreover, SAE improved glucose tolerance, attenuated pathological liver alterations and oxidative stress present in MetS. Obtained beneficial effects of SAE were more prominent in combination with changing dietary habits. Promising potential of SAE supplementation alone or in combination with different dietary protocols in triggering cardioprotection should be further examined in future.
PB  - MDPI, Basel
T2  - International Journal of Molecular Sciences
T1  - Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model
IS  - 1
VL  - 20
DO  - 10.3390/ijms20010006
ER  - 

@article{
author = "Jakovljević, Vladimir and Milić, Petar and Bradić, Jovana and Jeremić, Jovana and Živković, Vladimir and Srejović, Ivan and Nikolić-Turnić, Tamara and Milosavljević, Isidora and Jeremić, Nevena and Bolevich, Sergey and Labudović-Borović, Milica and Mitrović, Miroslav and Vučić, Vesna M.",
year = "2019",
abstract = "The aim of our study was to examine the effects of different dietary strategies, high-fat (HFd) or standard diet (Sd) alone or in combination with standardized oral supplementation (0.45 mL/kg/day) of Aronia melanocarpa extract (SAE) in rats with metabolic syndrome (MetS). SAE is an official product of pharmaceutical company Pharmanova (Belgrade, Serbia); however, the procedure for extraction was done by EU-Chem company (Belgrade, Serbia). Rats were divided randomly into six groups: control with Sd, control with Sd and SAE, MetS with HFd, MetS with HFd and SAE, MetS with Sd and MetS with Sd and SAE during 4 weeks. At the end of the 4-week protocol, cardiac function and liver morphology were assessed, while in the blood samples glucose, insulin, iron levels and systemic redox state were determined. Our results demonstrated that SAE had the ability to lower blood pressure and exert benefits on in vivo and ex vivo heart function. Moreover, SAE improved glucose tolerance, attenuated pathological liver alterations and oxidative stress present in MetS. Obtained beneficial effects of SAE were more prominent in combination with changing dietary habits. Promising potential of SAE supplementation alone or in combination with different dietary protocols in triggering cardioprotection should be further examined in future.",
publisher = "MDPI, Basel",
journal = "International Journal of Molecular Sciences",
title = "Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model",
number = "1",
volume = "20",
doi = "10.3390/ijms20010006"
}

Jakovljević, V., Milić, P., Bradić, J., Jeremić, J., Živković, V., Srejović, I., Nikolić-Turnić, T., Milosavljević, I., Jeremić, N., Bolevich, S., Labudović-Borović, M., Mitrović, M.,& Vučić, V. M.. (2019). Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model. in International Journal of Molecular Sciences
MDPI, Basel., 20(1).
https://doi.org/10.3390/ijms20010006

Jakovljević V, Milić P, Bradić J, Jeremić J, Živković V, Srejović I, Nikolić-Turnić T, Milosavljević I, Jeremić N, Bolevich S, Labudović-Borović M, Mitrović M, Vučić VM. Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model. in International Journal of Molecular Sciences. 2019;20(1).
doi:10.3390/ijms20010006 .

Jakovljević, Vladimir, Milić, Petar, Bradić, Jovana, Jeremić, Jovana, Živković, Vladimir, Srejović, Ivan, Nikolić-Turnić, Tamara, Milosavljević, Isidora, Jeremić, Nevena, Bolevich, Sergey, Labudović-Borović, Milica, Mitrović, Miroslav, Vučić, Vesna M., "Standardized Aronia melanocarpa Extract as Novel Supplement against Metabolic Syndrome: A Rat Model" in International Journal of Molecular Sciences, 20, no. 1 (2019),
https://doi.org/10.3390/ijms20010006 . .