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Toxicological Profile of Nanostructured Bone Substitute Based on Hydroxyapatite and Poly(lactide-co-glycolide) after Subchronic Oral Exposure of Rats
(MDPI, Basel, 2020)
Novel three-dimensional (3D) nanohydroxyapatite-PLGA scaffolds with high porosity was developed to better mimic mineral component and microstructure of natural bone. To perform a final assessment of this nanomaterial as a ...
Potential anti-melanoma activity of Imidazoline I1 receptor agonists
(European Association for Cancer Research, 2020)
Melanoma is the deadliest form of skin cancer. Despite the advancements in targeted
BRAF and MEK therapy and immunotherapies, metastatic melanoma patients still
have poor prognosis with a median survival of 9 months ...
Beneficial effect of walnuts on vascular tone is associated with Akt signalling, voltage-dependent calcium channel LTCC and ATP-sensitive potassium channel Kv1.2
(Taylor & Francis Ltd, Abingdon, 2020)
Consumption of walnuts is beneficial for cardiovascular health. To study walnut effects on proteins involved in vascular tone regulation, control and fructose-fed rats were subjected to walnut diet for 6 weeks. In contrast ...
Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease
(Royal Soc Chemistry, Cambridge, 2020)
Flavanol intake positively influences several cardiometabolic risk factors in humans. However, the specific molecular mechanisms of action of flavanols, in terms of gene regulation, in the cell types relevant to cardiometabolic ...
In Vivo and In Vitro Virulence Analysis of Four Genetically Distinct Toxoplasma gondii Lineage III Isolates
(MDPI, Basel, 2020)
Toxoplasma gondii archetypes II and III are mildly virulent, yet virulence of variant strains is largely unknown. While lineage II dominates in humans in Europe, lineage III strains are present in various intermediate ...
Assessing the symptoms of Internet gaming disorder among college/university students: An international validation study of a self-report / Procenjivanje simptoma poremećaja igranja kompjuterskih igara na internetu (eng. Internet Gaming Disorder) kod studenata - internacionalna validaciona studija mere samoprocene
(Društvo psihologa Srbije, Beograd, 2020)
The present study evaluated the psychometric properties of a self-report scale for assessing Internet Gaming Disorder (IGD) symptoms according to the DSM-5 and ICD-11 among 3270 college/univers ity students (2095 [64.1%] ...
Marked epithelial to mesenchymal transition in surgical margins of oral cancer-an in vitro study
(Spandidos Publ Ltd, Athens, 2020)
Epithelial to mesenchymal transition (EMT) is a feature of several types of human cancer, including oral squamous cell carcinoma (OSCC). In the present study, tumor and margin cell cultures obtained from patients with OSCC ...
Effectiveness of Expressive Writing in the Reduction of Psychological Distress During the COVID-19 Pandemic: A Randomized Controlled Trial
(Frontiers Media Sa, Lausanne, 2020)
Objective Due to the wide impact of the COVID-19 pandemic on mental health, the need for scalable interventions that can effectively reduce psychological distress has been recognized. Expressive writing (EW) can be beneficial ...
Characterization of personal solar ultraviolet radiation exposure using detrended fluctuation analysis
(Academic Press Inc Elsevier Science, San Diego, 2020)
Studies of personal solar ultraviolet radiation (pUVR) exposure are important to identify populations at-risk of excess and insufficient exposure given the negative and positive health impacts, respectively, of time spent ...