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ROS-NF kappa I' mediates TGF-beta 1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion
(Springer, Dordrecht, 2010)
TGF-beta 1 has been postulated as a pro-oncogenic factor in the late step of the tumoral progression. In transformed cells, TGF-beta 1 enhances the capacity to degrade the extracellular matrix, cell invasiveness and ...
SKIP is required for TGF-beta 1-induced epithelial mesenchymal transition and migration in transformed keratinocytes
(Wiley, Hoboken, 2010)
Transforming growth factor-beta 1 (TGF-beta 1) potently induces the epithelial-mesenchymal transition (EMT) during tumoral progression. Although Sky-interacting protein (SKIP) regulates TGF-beta 1-induced Smad activation, ...
Rac1 modulates TGF-beta 1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes
(Elsevier Science Bv, Amsterdam, 2010)
Transforming growth factor-beta 1 (TGF-beta 1) activates Rac1 GTPase in mouse transformed keratinocytes. Expression of a constitutively active Q61LRac1 mutant induced an epithelial to mesenchymal transition (EMT) linked ...