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Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii
(Oxford Univ Press, Oxford, 2002)
The efficacy of atovaquone (ATO) combined with clindamycin (CLI) against Toxoplasma gondii was examined in murine models of infection with a mouse-non-virulent (Me49) strain. Swiss-Webster mice inoculated by mouth with 10 ...
Approaches to mimic the complexity of the skeletal mesenchymal stem/stromal cell niche in vitro
(Ao Research Institute Davos-Ari, Davos, 2019)
Mesenchymal stem/stromal cells (MSCs) are an essential element of most modem tissue engineering and regenerative medicine approaches due to their multipotency and immunoregulatory functions. Despite the prospective value ...
Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
(Nature Publishing Group, London, 2017)
Chemotherapy in patients with inoperable or advanced breast cancer inevitably results in low-dose exposure of tumor-cell subset and senescence. Metabolically active senescent cells secrete multiple tumor promoting factors ...
Review Article Socio-economic determinants of micronutrient intake and status in Europe: a systematic review
(Cambridge Univ Press, Cambridge, 2014)
Objective To provide the evidence base for targeted nutrition policies to reduce the risk of micronutrient/diet-related diseases among disadvantaged populations in Europe, by focusing on: folate, vitamin B-12, Fe, Zn and ...
Effects of anthocyanins and their gut metabolites on adenosine diphosphate-induced platelet activation and their aggregation with monocytes and neutrophils
(Elsevier Science Inc, New York, 2018)
Accumulating evidence suggests that anthocyanins play an important role in the cardioprotective effects associated with consumption of anthocyanin-rich foods. These benefits may partly be attributed to their effects on ...
The Role of the TGF-beta Coreceptor Endoglin in Cancer
(Hindawi Ltd, London, 2010)
Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-beta) that interacts with type I and type II TGF-beta receptors and modulates TGF-beta signaling. Endoglin is overexpressed in the ...
Bosentan and losartan ameliorate acute renal failure associated with mild but not strong NO blockade
(Oxford Univ Press, Oxford, 2007)
Background. Acute renal failure (ARF) is a devastating illness, especially when it occurs in various conditions with impaired nitric oxide (NO) synthesis, such as arterial hypertension, heart failure and some renal diseases. ...
Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production
(Elsevier Science Inc, New York, 2009)
Objective. We have previously shown that nitric oxide (NO) is involved in the hydroxyurea-induced increase of gamma-globin gene expression in cultured human erythroid progenitor cells and that hydroxyurea increases NO ...
How does the quality of surveys for nutrient intake adequacy assessment compare across Europe? A scoring system to rate the quality of data in such surveys
(Cambridge Univ Press, Cambridge, 2009)
Research was conducted within the EURopean micronutrient RECommendations Aligned (EURRECA) Network of Excellence, to find the best practice in assessing nutrient intakes. Objectives include: to search for and use data on ...
Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players
(Shanghai Univ Sport, Shanghai, 2017)
Background: Intensive exercise changes physiological need for glucose and several biochemical pathways responsible for its metabolism response. Among them are those which involve insulin, insulin-like growth factor (IGF-1), ...