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Plasma phospholipid fatty acid patterns are associated with adiposity and the metabolic syndrome in black South Africans: a cross-sectional study
(Clinics Cardive Publ Pty Ltd, Durbanville, 2019)
Background: Diets rich in n-6 polyunsaturated fatty acids (PUEAs) and saturated fatty acids (SFA) have been associated. with increased risk of obesity and the metabolic syndrome (MetS), but the evidence is inconsistent, ...
Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study
(Sciendo, Warsaw, 2012)
Isolated rat adrenal medulla was analyzed by light and electron microscope after an acute (60 min) exposure to high ambient temperature (38A degrees C). Under these conditions there was a significant rise in plasma adrenaline ...
Pharmacogenetics in cancer therapy-8 years of experience at the Institute for Oncology and Radiology of Serbia
(Balkan Union of Oncology (B.U.ON.), 2016)
Purpose: Pharmacogenetics is a study of possible mechanism by which an individual's response to drugs is genetically determined by variations in their DNA sequence. The aim of pharmacogenetics is to identify the optimal ...
Transcriptional profiling of erythroid progenitors from G-CSF mobilized and nonmobilized peripheral blood
(Balkan Union of Oncology (B.U.ON.), 2014)
Purpose: The purpose of this study was to examine the gene expression profile of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood (mPB)-derived progenitors, used in transplantation. Methods: We ...
Finger tapping analysis in patients with Parkinson's disease and atypical parkinsonism
(Elsevier Sci Ltd, Oxford, 2016)
The goal of this study was to investigate repetitive finger tapping patterns in patients with Parkinson's disease (PD), progressive supranuclear palsy-Richardson syndrome (PSP-R), or multiple system atrophy of parkinsonian ...
Gait in drug naive patients with de novo Parkinson's disease - altered but symmetric
(Maney Publishing, Leeds, 2015)
Background: Motor symptoms in Parkinson's disease (PD) are typically asymmetrical. Early stage of PD is characterised with a predominantly unilateral appearance of tremor, rigidity and bradykinesia, with or without axial ...
Selection of gait parameters for differential diagnostics of patients with de novo Parkinson's disease
(Taylor & Francis Ltd, Abingdon, 2017)
Background: Gait disturbances are an integral part of clinical manifestations of Parkinson's disease (PD), even in the initial stages of the disease. Our goal was to identify the set of spatio-temporal gait parameters that ...
The impact of occupational stress factors on temporary work disability related to arterial hypertension and its complications
(Taylor & Francis Ltd, Abingdon, 2017)
Aim. To determine which specific groups of occupational stress factors influence the duration of temporary work disability related to arterial hypertension and joint complications/co-morbidities. Methodology. Workers ...
Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation
(Bentham Science Publ Ltd, Sharjah, 2018)
Background: IL-17A is a founding member of the IL-17 family that has been implicated in the pathogenesis of inflammatory-associated diseases such as cancer and autoimmune disease. In cancer, IL-17A participates in many key ...
Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: A New Target for Sepsis
(Bentham Science Publ Ltd, Sharjah, 2019)
Background: Main pathological features detected during sepsis and endotoxemia include over-secretion of pro-inflammatory cytokines and multiorgan dysfunction syndrome (MODS). Unfortunately, current clinical efforts to treat ...