Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study
Abstract
Isolated rat adrenal medulla was analyzed by light and electron microscope after an acute (60 min) exposure to high ambient temperature (38A degrees C). Under these conditions there was a significant rise in plasma adrenaline and noradrenaline. Stereological investigation by light microscopy showed a significant decrease in volume density of cells and an increase in the interstitium. At the ultrastructural level, the profile area of cells, nuclei and cytoplasm of adrenaline cells were significantly decreased. After the heat stress numbers of resting granules in adre naline and noradrenaline cells were significantly reduced, while the numbers of altered granules and empty containers in both types of adrenomedullar cells were significantly increased.
Keywords:
Rat / Heat stress / Ultrastructure / Adrenaline cells / Noradrenaline cellsSource:
Central European Journal of Biology, 2012, 7, 4, 603-610Publisher:
- Sciendo, Warsaw
Funding / projects:
DOI: 10.2478/s11535-012-0044-1
ISSN: 1895-104X
WoS: 000304880000004
Scopus: 2-s2.0-84861840697
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Institution/Community
Institut za medicinska istraživanjaTY - JOUR AU - Petrovic-Kosanović, Dragana AU - Čakić-Milošević, Maja AU - Budeč, Mirela AU - Koko, Vesna PY - 2012 UR - http://rimi.imi.bg.ac.rs/handle/123456789/414 AB - Isolated rat adrenal medulla was analyzed by light and electron microscope after an acute (60 min) exposure to high ambient temperature (38A degrees C). Under these conditions there was a significant rise in plasma adrenaline and noradrenaline. Stereological investigation by light microscopy showed a significant decrease in volume density of cells and an increase in the interstitium. At the ultrastructural level, the profile area of cells, nuclei and cytoplasm of adrenaline cells were significantly decreased. After the heat stress numbers of resting granules in adre naline and noradrenaline cells were significantly reduced, while the numbers of altered granules and empty containers in both types of adrenomedullar cells were significantly increased. PB - Sciendo, Warsaw T2 - Central European Journal of Biology T1 - Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study EP - 610 IS - 4 SP - 603 VL - 7 DO - 10.2478/s11535-012-0044-1 UR - conv_2761 ER -
@article{ author = "Petrovic-Kosanović, Dragana and Čakić-Milošević, Maja and Budeč, Mirela and Koko, Vesna", year = "2012", abstract = "Isolated rat adrenal medulla was analyzed by light and electron microscope after an acute (60 min) exposure to high ambient temperature (38A degrees C). Under these conditions there was a significant rise in plasma adrenaline and noradrenaline. Stereological investigation by light microscopy showed a significant decrease in volume density of cells and an increase in the interstitium. At the ultrastructural level, the profile area of cells, nuclei and cytoplasm of adrenaline cells were significantly decreased. After the heat stress numbers of resting granules in adre naline and noradrenaline cells were significantly reduced, while the numbers of altered granules and empty containers in both types of adrenomedullar cells were significantly increased.", publisher = "Sciendo, Warsaw", journal = "Central European Journal of Biology", title = "Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study", pages = "610-603", number = "4", volume = "7", doi = "10.2478/s11535-012-0044-1", url = "conv_2761" }
Petrovic-Kosanović, D., Čakić-Milošević, M., Budeč, M.,& Koko, V.. (2012). Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study. in Central European Journal of Biology Sciendo, Warsaw., 7(4), 603-610. https://doi.org/10.2478/s11535-012-0044-1 conv_2761
Petrovic-Kosanović D, Čakić-Milošević M, Budeč M, Koko V. Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study. in Central European Journal of Biology. 2012;7(4):603-610. doi:10.2478/s11535-012-0044-1 conv_2761 .
Petrovic-Kosanović, Dragana, Čakić-Milošević, Maja, Budeč, Mirela, Koko, Vesna, "Effect of acute heat stress on rat adrenal medulla - a morphological and ultrastructural study" in Central European Journal of Biology, 7, no. 4 (2012):603-610, https://doi.org/10.2478/s11535-012-0044-1 ., conv_2761 .