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Interleukin-6 (IL-6) and low O-2 concentration (1%) synergize to improve the maintenance of hematopoietic stem cells (Pre-CFC)
(Wiley, Hoboken, 2007)
Low O-2 concentration (1%) favors the self-renewal of hematopoietic stem cells and inhibits committed progenitors (CFC). Since IL-6 influences both stem cells and committed progenitors at 20% O-2, we studied its effects ...
Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors
(Elsevier Science Bv, Amsterdam, 2006)
Toxoplasmosis is a globally distributed zoonosis with a clinical impact in the unborn fetus and in the immunosuppressed individual. In Serbia, studies of risk factors for Toxoplasma gondii infection in humans have shown ...
The efficacy of two protocols for inducing motor cortex plasticity in healthy humans - TMS study
(General Physiol And Biophysics, Bratislava, 2009)
Stimulation-induced plasticity represents an experimental model of motor cortex reorganization. It can be produced in awaked humans by combining the non-invasive electrical stimulation of somatosensory afferents via mixed ...
Possible mechanism of acute effect of ethanol on intestinal IgA expression in rat
(Elsevier Science Bv, Amsterdam, 2007)
The purpose of this study was to investigate the possible mechanism of acute effect of ethanol on IgA expression in rat intestine. To this end, adult female Wistar rats showing diestrus day I were treated with (a) ethanol ...
A longitudinal study of the relationship between galactosylation degree of IgG and rheumatoid factor titer and avidity during long-term immunization of rabbits with BSA
(Taylor & Francis Ltd, Abingdon, 2005)
Although IgG with reduced content of galactose has been implicated as important in the autoimmune rheumatoid factor (RF) response in rheumatoid arthritis (RA), relatively little is known about the temporal relationship ...
Effects of acute administration of ethanol on the rat adrenal cortex
(Alcohol Res Documentation Inc Cent Alcohol Stud Rutgers Univ, Piscataway, 2003)
Objective: The purpose of this study was to investigate the effect of a single dose of ethanol on rat adrenal cortex and to determine whether the estrous cycle can influence this effect of ethanol. Method: Adult female ...
Effects of Nitric Oxide on Red Blood Cell Development and Phenotype
(Current Topics in Developmental Biology, 2008)
Nitric oxide (NO) is a diffusible free radical generated primarily by NO synthases (NOS), isoenzymes that convert the l-arginine and molecular oxygen to citrulline and NO in cells. Endothelial cells as well as macrophages, ...
Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells
(Amer Soc Hematology, Washington, 2006)
Hydroxyurea is a cell-cycle-specific drug that has been used to treat myeloproliferative diseases and sickle cell anemia. We have recently shown that hydroxyurea, like nitric oxide (NO)-donor compounds, increased cGMP ...
Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity
(Academic Press Inc Elsevier Science, San Diego, 2007)
Recent reports have identified the proteasome as the primary degradation pathway for inducible, neuronal and endothelial nitric oxide synthase (NOS). We have demonstrated that hydroxyurea increased nitric oxide (NO) ...
The metabolic syndrome, an epidemic among HIV-infected patients on HAART
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2009)
Background: HAART has dramatically changed the prognosis of AIDS, but has led to long-term toxicities of antiretroviral drugs. A major chronic complication is the metabolic syndrome (MS), including hyperlipidemia, lipodystrophy ...