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Neutrophil Death in Myeloproliferative Neoplasms: Shedding More Light on Neutrophils as a Pathogenic Link to Chronic Inflammation
(MDPI, 2022)
Neutrophils are an essential component of the innate immune response, but their prolonged activation can lead to chronic inflammation. Consequently, neutrophil homeostasis is tightly regulated through balance between ...
Role of Corticosteroids in Drug-Induced Liver Injury. A Systematic Review
(Frontiers Media S.A., 2022)
Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear. ...
The Polymorphisms of Genes Encoding Catalytic Antioxidant Proteins Modulate the Susceptibility and Progression of Testicular Germ Cell Tumor
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
The simultaneous analysis of redox biomarkers and polymorphisms encoding for regulatory and catalytic antioxidant proteins was performed in order to evaluate their potential role in the development of testicular germ cell ...
Forest Fire Probability Mapping in Eastern Serbia: Logistic Regression versus Random Forest Method
(MDPI, 2021)
Forest fire risk has increased globally during the previous decades. The Mediterranean region is traditionally the most at risk in Europe, but continental countries like Serbia have experienced significant economic and ...
Assessment of the force-velocity relationship during vertical jumps: influence of the starting position, analysis procedures and number of loads
(Taylor & Francis Ltd, Abingdon, 2020)
This study aimed to compare the reliability and magnitude of the force-velocity (F-V) relationship parameters between the squat jumps performed from the 90 degrees (SJ90) and self-preferred knee angle (SJ(pref)). A secondary ...
Assessment of the force-velocity relationship during vertical jumps: influence of the starting position, analysis procedures and number of loads
(Taylor & Francis Ltd, Abingdon, 2020)
This study aimed to compare the reliability and magnitude of the force-velocity (F-V) relationship parameters between the squat jumps performed from the 90 degrees (SJ90) and self-preferred knee angle (SJ(pref)). A secondary ...
Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
(Pharmaceutics, 2022)
The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene expression due to the abnormal activation of histone ...
Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease
(Royal Soc Chemistry, Cambridge, 2020)
Flavanol intake positively influences several cardiometabolic risk factors in humans. However, the specific molecular mechanisms of action of flavanols, in terms of gene regulation, in the cell types relevant to cardiometabolic ...
Endothelial dysfunction in pregnancy metabolic disorders
(Elsevier, Amsterdam, 2020)
In recent years, the vascular endothelium has gained attention as a key player in the initiation and development of pregnancy disorders. Endothelium acts as an endocrine organ that preserves the homeostatic balance by ...
Specificity of 3D MSC Spheroids Microenvironment: Impact on MSC Behavior and Properties
(Springer, New York, 2020)
Mesenchymal stem cells (MSC) have been considered the promising candidates for the regenerative and personalized medicine due to their self-renewal potential, multilineage differentiation and immunomodulatory capacity. ...