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Effects of Adrenergic Receptor Stimulation on Human Hemostasis: A Systematic Review
(Springer Nature, 2023)
Catecholamine stimulation over adrenergic receptors results in a state of hypercoagulability. Chronic stress involves the release and increase in circulation of catecholamines and other stress related hormones. Numerous ...
Circulatory Imbalance of Essential and Toxic Trace Elements in Pre-dialysis and Hemodialysis Patients
(Wiley-Blackwell, 2022)
The status of essential and toxic trace elements in patients with different stages of chronic kidney disease (CKD) is still unclear and not well characterized. The present study examined the circulatory levels of a wide ...
Integrated in vitro – in vivo – in silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films
(Elsevier, 2023)
In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have ...
Exploring rural hospital admissions for diarrhoeal disease, malaria, pneumonia, and asthma in relation to temperature, rainfall and air pollution using wavelet transform analysis
(Elsevier, 2021)
Background:Climate variables impact human health and in an era of climate change, there is a pressing need to understand these relationships to best inform how such impacts are likely to change.ObjectivesThis study sought ...
BMP2 downregulates urokinase-type plasminogen activator via p38 MAPK: Implications in C2C12 cells myogenic differentiation
(Elsevier, 2021)
Bone morphogenetic protein (BMP)2 strongly affects the differentiation program of myoblast cells by inhibiting myogenesis and inducing osteogenic differentiation. In turn, extracellular matrix (ECM) proteinases, such as ...
Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans – Evidence from untargeted mRNA and miRNA studies
(Elsevier, 2022)
Cardiovascular and metabolic disorders present major causes of mortality in the ageing population. Polyphenols present in human diets possess cardiometabolic protective properties, however their underlying molecular ...
The force-velocity relationship obtained during the squat jump exercise is meaningfully influenced by the initial knee angle
(Routledge Journals, Taylor & Francis Ltd, Abingdon, 2020)
This study aimed to compare the magnitude of the force-velocity (F-V) relationship parameters (maximum force [F-0], maximum velocity [V-0], F-V slope, and maximum power [P-max]) between the squat jumps (SJ) performed from ...
Selectivity of polyclonal repertoire of anti‐microbial IgA and its subclasses in saliva and serum in humans
(Wiley-Blackwell, 2022)
Increased interest in microbiota calls for the thorough analysis of antibody reactivity to different microorganisms. As salivary IgA represents the first line of defence against microorganisms contacting mucosal surfaces, ...
Hyperbaric oxygenation protects the kidney against ischemia-reperfusion injury
(Undersea & Hyperbaric Medical Soc Inc, Durham, 2020)
Background: Acute kidney injury (AKI) as a consequence of ischemia is a common clinical event that can lead to unacceptably high morbidity and mortality. Hyperbaric oxygen (HBO2) preconditioning has been shown to prevent ...