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Neutrophil Death in Myeloproliferative Neoplasms: Shedding More Light on Neutrophils as a Pathogenic Link to Chronic Inflammation
(MDPI, 2022)
Neutrophils are an essential component of the innate immune response, but their prolonged activation can lead to chronic inflammation. Consequently, neutrophil homeostasis is tightly regulated through balance between ...
Effects of apocynin treatment and HBO preconditioning on immunohistochemical 4-HNE, HIF alpha, HIF2 alpha and NGAL tissue expression in postiscemic acute kidney injury in SHR rats
(Wolters Kluwer Health, Inc., 2022)
Objective:
Oxidative stress has been considered as a central aggravating factor in the development of postischemic acute kidney injury (AKI). 4-hydroxynonenal (4-HNE) is a product of lipid peroxidation and may serve as ...
Differences in mouse strains determine the outcome of Der p 2 allergy induction protocols
(Elsevier, 2022)
In vivo animal models can provide worthy information on various aspects of asthma mechanism and pathogenesis. The genetic predisposition and phenotype of mice may affect the immune response itself. Here we compare the early ...
Immunohistochemical expression of heme oxygenase-1, 4-hydroxynonenal and hypoxia inducible factors (1α, 1β, 2α) after HBO preconditioning in postischemic acute kidney injury induced in spontaneously hypertensive
(46th EUBS Annual Scientific Meeting, 31.08.-03.09.2022. Prague, Czech Republic - Abstract & Conference Book, 2022)
Exosomes and exosome-mimetics as targeted drug carriers: Where we stand and what the future holds?
(Elsevier, 2022)
Exosomes are a sub-group of extracellular vesicles, playing an important part in a cell-cell communication in many physiological and pathological conditions. Their size and competence for transferring material to recipient ...
Effects of NADPH oxidase blockade and hyperbaric oxygen preconditioning on 4-HNE, NGAL, and HO-1 tissue expression in postischemic acute kidney injury induced in spontaneously hypertensive rat
(European Section of the International Academy of Cardiovascular Sciences, 2022)
Kidney disease represents a serious global health problem. Free radicals and prooxidants produced during ischemic acute kidney injury (AKI) may further aggravate the course of the disease and play a role in the pathogenesis ...
Three Episodes of COVID-19 in a Nursing Home in Belgrade, Serbia
(Belgrade: MEDAPP Association, 2022)
Background: Over the two years of the COVID-19 pandemic, the elderly in nursing
homes (NH) have been hit particularly hard.
Methods: We conducted a retrospective study of 3 episodes of COVID-19 in one NH in
suburban ...
Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans – Evidence from untargeted mRNA and miRNA studies
(Elsevier, 2022)
Cardiovascular and metabolic disorders present major causes of mortality in the ageing population. Polyphenols present in human diets possess cardiometabolic protective properties, however their underlying molecular ...
Regulation of S100As Expression by Inflammatory Cytokines in Chronic Lymphocytic Leukemia
(MDPI, 2022)
The calcium-binding proteins S100A4, S100A8, and S100A9 are upregulated in chronic lymphocytic leukemia (CLL), while the S100A9 promotes NF-κB activity during disease progression. The S100-protein family has been involved ...
Crosstalk between dietary patterns, obesity and nonalcoholic fatty liver disease
(World Journal of Gastroenterology, 2022)
The prevalence of nonalcoholic fatty liver disease (NAFLD) is rising worldwide, paralleling the epidemic of obesity. The liver is a key organ for the metabolism of proteins, fats and carbohydrates. Various types of fats ...