Vasiljević, Nada

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  • Vasiljević, Nada (2)
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Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study

Grabež, Milkica; Škrbić, Ranko; Stojiljković, Miloš P.; Rudić-Grujić, Vesna; Paunović, Marija P.; Arsić, Aleksandra; Petrović, Snježana; Vučić, Vesna M.; Mirjanić-Azarić, Bosa; Savikin, Katarina; Menković, Nebojša; Janković, Teodora; Vasiljević, Nada

(Elsevier, Amsterdam, 2020)

TY  - JOUR
AU  - Grabež, Milkica
AU  - Škrbić, Ranko
AU  - Stojiljković, Miloš P.
AU  - Rudić-Grujić, Vesna
AU  - Paunović, Marija P.
AU  - Arsić, Aleksandra
AU  - Petrović, Snježana
AU  - Vučić, Vesna M.
AU  - Mirjanić-Azarić, Bosa
AU  - Savikin, Katarina
AU  - Menković, Nebojša
AU  - Janković, Teodora
AU  - Vasiljević, Nada
PY  - 2020
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1033
AB  - Pomegranate peel contains high levels of various phytochemicals. We evaluated the effects of pomegranate peel extract (PoPEx) consumption on plasma lipid profile, fatty acids (FA) level and blood pressure (BP) in patients with diabetes mellitus type 2 (DMT2). Thirty-seven subjects were recruited in this double blind, placebo controlled randomized trial. The study group (n = 19) received over 8 week's capsules containing PoPEx twice a daily, while the placebo group received placebo. Treatment with PoPEx induced a significant lowering of both systolic and diastolic BP. The plasma levels of triglycerides, low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C), and HbA1c were significantly decreased, while the level of HDL-C was significantly increased, compared with placebo intake. Moreover, the PoPEX treatment significantly improved the plasma lipids fatty acids content. It is concluded that consumption of PoPEx in DMT2 subject had favourable effects on some metabolic parameters, BP, lipid profile and plasma lipid FA composition.
PB  - Elsevier, Amsterdam
T2  - Journal of Functional Foods
T1  - Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study
SP  - 103692
VL  - 64
DO  - 10.1016/j.jff.2019.103692
ER  - 
@article{
author = "Grabež, Milkica and Škrbić, Ranko and Stojiljković, Miloš P. and Rudić-Grujić, Vesna and Paunović, Marija P. and Arsić, Aleksandra and Petrović, Snježana and Vučić, Vesna M. and Mirjanić-Azarić, Bosa and Savikin, Katarina and Menković, Nebojša and Janković, Teodora and Vasiljević, Nada",
year = "2020",
abstract = "Pomegranate peel contains high levels of various phytochemicals. We evaluated the effects of pomegranate peel extract (PoPEx) consumption on plasma lipid profile, fatty acids (FA) level and blood pressure (BP) in patients with diabetes mellitus type 2 (DMT2). Thirty-seven subjects were recruited in this double blind, placebo controlled randomized trial. The study group (n = 19) received over 8 week's capsules containing PoPEx twice a daily, while the placebo group received placebo. Treatment with PoPEx induced a significant lowering of both systolic and diastolic BP. The plasma levels of triglycerides, low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C), and HbA1c were significantly decreased, while the level of HDL-C was significantly increased, compared with placebo intake. Moreover, the PoPEX treatment significantly improved the plasma lipids fatty acids content. It is concluded that consumption of PoPEx in DMT2 subject had favourable effects on some metabolic parameters, BP, lipid profile and plasma lipid FA composition.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Functional Foods",
title = "Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study",
pages = "103692",
volume = "64",
doi = "10.1016/j.jff.2019.103692"
}
Grabež, M., Škrbić, R., Stojiljković, M. P., Rudić-Grujić, V., Paunović, M. P., Arsić, A., Petrović, S., Vučić, V. M., Mirjanić-Azarić, B., Savikin, K., Menković, N., Janković, T.,& Vasiljević, N.. (2020). Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study. in Journal of Functional Foods
Elsevier, Amsterdam., 64, 103692.
https://doi.org/10.1016/j.jff.2019.103692
Grabež M, Škrbić R, Stojiljković MP, Rudić-Grujić V, Paunović MP, Arsić A, Petrović S, Vučić VM, Mirjanić-Azarić B, Savikin K, Menković N, Janković T, Vasiljević N. Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study. in Journal of Functional Foods. 2020;64:103692.
doi:10.1016/j.jff.2019.103692 .
Grabež, Milkica, Škrbić, Ranko, Stojiljković, Miloš P., Rudić-Grujić, Vesna, Paunović, Marija P., Arsić, Aleksandra, Petrović, Snježana, Vučić, Vesna M., Mirjanić-Azarić, Bosa, Savikin, Katarina, Menković, Nebojša, Janković, Teodora, Vasiljević, Nada, "Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study" in Journal of Functional Foods, 64 (2020):103692,
https://doi.org/10.1016/j.jff.2019.103692 . .
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General psychopathology and impulsivity as the pretreatment predictors of medical nutrition therapy outcome in the overweight and obese women

Tepšić-Ostojić, Vesna; Ristić-Medić, Danijela; Mraović, Tatjana; Bukumirić, Zoran; Vasiljević, Nada; Latas, Milan

(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2019)

TY  - JOUR
AU  - Tepšić-Ostojić, Vesna
AU  - Ristić-Medić, Danijela
AU  - Mraović, Tatjana
AU  - Bukumirić, Zoran
AU  - Vasiljević, Nada
AU  - Latas, Milan
PY  - 2019
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/926
AB  - Background/Aim. Obesity is the chronic disease and health threatening condition. The number of obese people in the world has taken epidemic conditions. Medical nutritional therapy is the first choice in the treatment of obesity, but it is also accompanied with a great percentage of attrition and a significant weight regain. The aim of our study was to evaluate if psychiatric and specific psychological factors (impulsivity) could be the predictors of successful weight loss. Methods. A study sample consisted of 84 consecutive overweight/obesity women, 20 to 40 years old, who were willing to adhere to the medical nutrition therapy after the initial anthropometric measurements were performed. All participants received a personalized nutritional counseling and a daily diet treatment with 20% caloric restriction from estimated daily energy requirement. At the beginning of the study, the 90-item Symptom Check-list (SCL-90) and the 30-item Barratt Impulsiveness scale (BIS11) were administrated. At the end of six months of caloric restriction, the conventional diet therapy and control weight measurement, the patients were divided into two groups: the group I - 40 participants (48%) who lost ≥ 10% of their initial body weight (successful group) and the group II - 44 participants (52%) who lost  lt  10% of their initial weight (unsuccessful). Results. There were no significant differences between groups in the demographic data (age, education level, employment, marital status), baseline anthropometric measurements, and in the general psychopathology total score. Groups I and II were significantly different in the total BIS-11 score (p  lt  0.001) and in Factor II (motor impulsivity) (p  lt  0.05). Conclusion. Even though the successful and unsuccessful diet responded participants did not differ in the general psychopathology and symptom dimensions, our results pointed out impulsivity as a discriminative factor between them. The total impulsivity and Factor II (motor impulsivity) as an indicator of binge eating were higher in the unsuccessfully responding overweight/obese women on the conventional diet treatment. A focus on impulsivity in a psychotherapeutic work might lead to better outcomes in the medical nutrition therapy.
AB  - Uvod/Cilj. Gojaznost je hronično oboljenje sa značajnim nepovoljnim efektima na zdravlje, a broj gojaznih osoba u svetu dostigao je epidemijske razmere. Medicinska nutritivna terapija je terapija izbora, ali je njena uspešnost ograničena zbog značajnog procenta odustajanja, kao i ponovnog dobijanja na težini koje je prate. Cilj ove studije je bio da se proceni da li psihijatrijski i specifični psihološki faktori (impulsivnost) mogu biti pokazatelji pozitivnog ishoda lečenja. Metode. Studijom je bilo obuhvaćeno ukupno 84 predgojaznih i gojaznih žena životnog doba 20-40 godina, koje su bile motivisane za medicinsku nutritivnu terapiju. Sve ispitanice su prošle individualno savetovanje i dobile dnevni plan ishrane koji je podrazumevao kalorijsku restrikciju od 20% u odnosu na procenjene dnevne energetske potrebe. Na početku studije sprovedeno je antropometrijsko merenje i primenjene su Lista simptoma od 90 pitanja (90item Symptom Check-list) i Baratova skala impulsivnosti (Barratt Impulsiveness scale (BIS-11)). Nakon šest meseci primene kalorijski restriktivnog načina ishrane ponovljena su antropometrijska merenja. Ispitanice su podeljene u dve grupe: 40 ispitanica (48%) koje su izgubile ≥ 10% od početne telesne mase (uspešne) i 44 ispitanice (52%) koje su izgubile  lt  10% od početne telesne mase (neuspešne). Rezultati. Nije bilo značajne razlike između grupa ispitanica u odnosu na demografske karakteristike (godine života, stepen obrazovanja, zaposlenost, bračni status) i antropometrijske parametre na početku studije, kao i na skor opšte psihopatologije i dimenzije simptoma. Statistički značajna razlika između uspešnih i neuspešnih predgojaznih/gojaznih ispitanica dobijena je za ukupni BIS-11 skor (p  lt  0.001) i za Faktor II (motorna impulsivnost) (p  lt  0.05). Zaključak. Ispitanice sa ponovljenim lošim odgovorom nisu se razlikovale po opštoj psihopatologiji od onih sa uspešnim odgovorom na nutritivnu terapiju. Naši rezultati ukazuju na impulsivnost kao mogući pokazatelj ishoda lečenja. Ukupna impulsivnost i motorna impulsivnost kao indikator povremenog impulsivnog prejedanja bili su viši u grupi predgojazih/gojaznih ispitanica koje nisu postigle terapijski cilj. Psihoterapijski rad na impulsivnosti možda bi mogao doprineti boljem ishodu medicinske nutritivne terapije.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - General psychopathology and impulsivity as the pretreatment predictors of medical nutrition therapy outcome in the overweight and obese women
T1  - Opšta psihopatologija i impulsivnost kao pokazatelji potencijalnog ishoda medicinske nutritivne terapije kod predgojaznih i gojaznih žena
EP  - 1109
IS  - 11
SP  - 1103
VL  - 76
DO  - 10.2298/VSP171107184T
ER  - 
@article{
author = "Tepšić-Ostojić, Vesna and Ristić-Medić, Danijela and Mraović, Tatjana and Bukumirić, Zoran and Vasiljević, Nada and Latas, Milan",
year = "2019",
abstract = "Background/Aim. Obesity is the chronic disease and health threatening condition. The number of obese people in the world has taken epidemic conditions. Medical nutritional therapy is the first choice in the treatment of obesity, but it is also accompanied with a great percentage of attrition and a significant weight regain. The aim of our study was to evaluate if psychiatric and specific psychological factors (impulsivity) could be the predictors of successful weight loss. Methods. A study sample consisted of 84 consecutive overweight/obesity women, 20 to 40 years old, who were willing to adhere to the medical nutrition therapy after the initial anthropometric measurements were performed. All participants received a personalized nutritional counseling and a daily diet treatment with 20% caloric restriction from estimated daily energy requirement. At the beginning of the study, the 90-item Symptom Check-list (SCL-90) and the 30-item Barratt Impulsiveness scale (BIS11) were administrated. At the end of six months of caloric restriction, the conventional diet therapy and control weight measurement, the patients were divided into two groups: the group I - 40 participants (48%) who lost ≥ 10% of their initial body weight (successful group) and the group II - 44 participants (52%) who lost  lt  10% of their initial weight (unsuccessful). Results. There were no significant differences between groups in the demographic data (age, education level, employment, marital status), baseline anthropometric measurements, and in the general psychopathology total score. Groups I and II were significantly different in the total BIS-11 score (p  lt  0.001) and in Factor II (motor impulsivity) (p  lt  0.05). Conclusion. Even though the successful and unsuccessful diet responded participants did not differ in the general psychopathology and symptom dimensions, our results pointed out impulsivity as a discriminative factor between them. The total impulsivity and Factor II (motor impulsivity) as an indicator of binge eating were higher in the unsuccessfully responding overweight/obese women on the conventional diet treatment. A focus on impulsivity in a psychotherapeutic work might lead to better outcomes in the medical nutrition therapy., Uvod/Cilj. Gojaznost je hronično oboljenje sa značajnim nepovoljnim efektima na zdravlje, a broj gojaznih osoba u svetu dostigao je epidemijske razmere. Medicinska nutritivna terapija je terapija izbora, ali je njena uspešnost ograničena zbog značajnog procenta odustajanja, kao i ponovnog dobijanja na težini koje je prate. Cilj ove studije je bio da se proceni da li psihijatrijski i specifični psihološki faktori (impulsivnost) mogu biti pokazatelji pozitivnog ishoda lečenja. Metode. Studijom je bilo obuhvaćeno ukupno 84 predgojaznih i gojaznih žena životnog doba 20-40 godina, koje su bile motivisane za medicinsku nutritivnu terapiju. Sve ispitanice su prošle individualno savetovanje i dobile dnevni plan ishrane koji je podrazumevao kalorijsku restrikciju od 20% u odnosu na procenjene dnevne energetske potrebe. Na početku studije sprovedeno je antropometrijsko merenje i primenjene su Lista simptoma od 90 pitanja (90item Symptom Check-list) i Baratova skala impulsivnosti (Barratt Impulsiveness scale (BIS-11)). Nakon šest meseci primene kalorijski restriktivnog načina ishrane ponovljena su antropometrijska merenja. Ispitanice su podeljene u dve grupe: 40 ispitanica (48%) koje su izgubile ≥ 10% od početne telesne mase (uspešne) i 44 ispitanice (52%) koje su izgubile  lt  10% od početne telesne mase (neuspešne). Rezultati. Nije bilo značajne razlike između grupa ispitanica u odnosu na demografske karakteristike (godine života, stepen obrazovanja, zaposlenost, bračni status) i antropometrijske parametre na početku studije, kao i na skor opšte psihopatologije i dimenzije simptoma. Statistički značajna razlika između uspešnih i neuspešnih predgojaznih/gojaznih ispitanica dobijena je za ukupni BIS-11 skor (p  lt  0.001) i za Faktor II (motorna impulsivnost) (p  lt  0.05). Zaključak. Ispitanice sa ponovljenim lošim odgovorom nisu se razlikovale po opštoj psihopatologiji od onih sa uspešnim odgovorom na nutritivnu terapiju. Naši rezultati ukazuju na impulsivnost kao mogući pokazatelj ishoda lečenja. Ukupna impulsivnost i motorna impulsivnost kao indikator povremenog impulsivnog prejedanja bili su viši u grupi predgojazih/gojaznih ispitanica koje nisu postigle terapijski cilj. Psihoterapijski rad na impulsivnosti možda bi mogao doprineti boljem ishodu medicinske nutritivne terapije.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "General psychopathology and impulsivity as the pretreatment predictors of medical nutrition therapy outcome in the overweight and obese women, Opšta psihopatologija i impulsivnost kao pokazatelji potencijalnog ishoda medicinske nutritivne terapije kod predgojaznih i gojaznih žena",
pages = "1109-1103",
number = "11",
volume = "76",
doi = "10.2298/VSP171107184T"
}
Tepšić-Ostojić, V., Ristić-Medić, D., Mraović, T., Bukumirić, Z., Vasiljević, N.,& Latas, M.. (2019). General psychopathology and impulsivity as the pretreatment predictors of medical nutrition therapy outcome in the overweight and obese women. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(11), 1103-1109.
https://doi.org/10.2298/VSP171107184T
Tepšić-Ostojić V, Ristić-Medić D, Mraović T, Bukumirić Z, Vasiljević N, Latas M. General psychopathology and impulsivity as the pretreatment predictors of medical nutrition therapy outcome in the overweight and obese women. in Vojnosanitetski pregled. 2019;76(11):1103-1109.
doi:10.2298/VSP171107184T .
Tepšić-Ostojić, Vesna, Ristić-Medić, Danijela, Mraović, Tatjana, Bukumirić, Zoran, Vasiljević, Nada, Latas, Milan, "General psychopathology and impulsivity as the pretreatment predictors of medical nutrition therapy outcome in the overweight and obese women" in Vojnosanitetski pregled, 76, no. 11 (2019):1103-1109,
https://doi.org/10.2298/VSP171107184T . .
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