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Regional hemodynamics after chronic nitric oxide inhibition in spontaneously hypertensive rats
(Elsevier Science Inc, New York, 2000)
Background: Inhibition of nitric oxide (NO) synthase by L-arginine analogs is associated with elevation of blood pressure in rats. Because endothelium-dependent vasomotion in different vascular beds is not homogenous, the ...
Bosentan and losartan ameliorate acute renal failure associated with mild but not strong NO blockade
(Oxford Univ Press, Oxford, 2007)
Background. Acute renal failure (ARF) is a devastating illness, especially when it occurs in various conditions with impaired nitric oxide (NO) synthesis, such as arterial hypertension, heart failure and some renal diseases. ...