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Urokinase Type Plasminogen Activator and the Molecular Mechanisms of its Regulation in Cancer
(Bentham Science Publ Ltd, Sharjah, 2017)
Background: Urokinase type plasminogen activator (uPA) is a 53-kDa serine protease initially synthesized as a catalytically inactive single chain polypeptide. Inactive-uPA is subject to proteolytic cleavage, which results ...
Metabolic Plasticity of Stem Cells and Macrophages in Cancer
(Frontiers Media Sa, Lausanne, 2017)
In addition to providing essential molecules for the overall function of cells, metabolism plays an important role in cell fate and can be affected by microenvironmental stimuli as well as cellular interactions. As a ...