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TGF-β and MMPs: A complex regulatory loop involved in tumor progression
(Matrix Metalloproteinases: Biology, Functions & Clinical Implications, 2012)
Transforming growth factor-β (TGF-β) has a dual and contradictory role in cancer. It is a tumor suppressor at early stages of tumor formation by virtue of its growth inhibitory and pro-apoptotic functions. However, at later ...
Eicosapentaenoic acid: The role in malignant diseases
(Eicosapentaenoic Acid: Sources, Health Effects & Role in Disease Prevention, 2012)
A number of epidemiological and experimental evidences have linked polyunsaturated fatty acids (PUFA) of n-3 series to reduced cancer risk. Particularly the long chain n-3 PUFA eicosapentaenoic acid (EPA) and docosahexaenoic ...