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Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation
(Bentham Science Publ Ltd, Sharjah, 2018)
Background: IL-17A is a founding member of the IL-17 family that has been implicated in the pathogenesis of inflammatory-associated diseases such as cancer and autoimmune disease. In cancer, IL-17A participates in many key ...
Novel Patents and Cancer Therapies for Transforming Growth Factor-Beta and Urokinase Type Plasminogen Activator: Potential Use of Their Interplay in Tumorigenesis
(Bentham Science Publ Ltd, Sharjah, 2014)
Transforming growth factor beta (TGF-beta) plays different roles in health and disease. TGF-beta has been assumed as a dual factor in tumor growth, since it can repress epithelial tumor development in early stages, while ...