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The mechanisms of the antihypertensive action of heparin in spontaneously hypertensive rats
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1997)
The aim of this study was to examine the effects of heparin on blood pressure in spontaneously hypertensive rats (SHR). Chronic subcutaneous administration of heparin consistenly lowers blood pressure in hypertensive rats. ...
Effects of losartan, tempol, and their combination on renal nitric oxide synthases in the animal model of chronic kidney disease
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2017)
Down-regulation of nitric oxide synthase (NOS) and NO defi ciency in the kidneys have been implicated in the pathogenesis of chronic kidney disease (CKD). In this study we examined the effects of losartan, tempol, and ...
Combined angiotensin II type-1 receptor blockade and superoxide anion scavenging affect the post-ischemic kidney in hypertensive rats / Uticaj blokade receptora tip 1 za angotenzin II udružene sa uklanjanjem superoksidnog anjona na postishemični bubreg kod pacova sa urođenom hipertenzijom
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2016)
Ischemic acute kidney injury is characterized by renal vasoconstriction, filtration failure, tubular obstruction, tubular backleak and overproduction of angiotensin II and reactive oxygen species. Considering this complexity, ...