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Hydroxyurea Induces Bone Marrow Mesenchymal Stromal Cells Senescence and Modifies Cell Functionality In Vitro
(MDPI, 2021)
Hydroxyurea (HU) is an antineoplastic agent that functions as an antimetabolite compound by inhibiting the ribonucleotide reductase. HU acts mainly as a cytostatic drug that through DNA replication stress may trigger a ...
Individual Resonant Frequencies at Low-Gamma Range and Cognitive Processing Speed
(MDPI, 2021)
Brain electrophysiological activity within the low gamma frequencies (30–80 Hz) has been proposed to reflect information encoding and transfer processes. The 40-Hz auditory steadystate response (40-Hz ASSR) is frequently ...
Tumorigenic Aspects of MSC Senescence—Implication in Cancer Development and Therapy
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
As an organism ages, many physiological processes change, including the immune system. This process, called immunosenescence, characterized by abnormal activation and imbalance of innate and adaptive immunity, leads to a ...