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Overexpression of the Angiogenic Tetrapeptide AcSDKP in Human Malignant Tumors
(Int Inst Anticancer Research, Athens, 2008)
Background: The natural tetrapeptide acetyl-SerAsp-Lys-Pro (AcSDKP), generated from thymosin beta 4 following its cleavage by prolyl oligopeptidase (POP), is a physiological stimulator of angiogenesis. Because of the ...
Evidence for an association of high levels of endogenous Acetyl-Ser-Asp-Lys-Pro, a potent mediator of angiogenesis, with acute myeloid leukemia development
(Taylor & Francis Ltd, Abingdon, 2006)
Evidence from clinical and laboratory studies suggests that angiogenesis is important in the progression of solid tumours and hematologic malignancies. We have shown that the naturally occurring tetrapeptide Acetyl-Ser-Asp-Lys-Pro ...
In vitro effects of IL-17 on angiogenic properties of endothelial cells in relation to oxygen levels
(Wiley, Hoboken, 2013)
The aim of this study has been to elucidate how different oxygen levels impact the effects of Interleukin-17 (IL-17) on angiogenic properties of endothelial cells. Two endothelial cell lines, mouse MS-1 and human EA.hy ...