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The metabolic syndrome, an epidemic among HIV-infected patients on HAART
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2009)
Background: HAART has dramatically changed the prognosis of AIDS, but has led to long-term toxicities of antiretroviral drugs. A major chronic complication is the metabolic syndrome (MS), including hyperlipidemia, lipodystrophy ...
Ruptured abdominal aortic aneurysms: Factors influencing early survival
(Elsevier Science Inc, New York, 2005)
In this study we aimed to define relevant prognostic predictors for the outcome of surgical treatment of ruptured abdominal aortic aneurysms. The study included 406 consecutive patients treated between January 1991 and ...
Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity
(Academic Press Inc Elsevier Science, San Diego, 2007)
Recent reports have identified the proteasome as the primary degradation pathway for inducible, neuronal and endothelial nitric oxide synthase (NOS). We have demonstrated that hydroxyurea increased nitric oxide (NO) ...
Effects of gamma-radiation on cell growth, cycle arrest, death, and superoxide dismutase expression by DU145 human prostate cancer cells
(Assoc Bras Divulg Cientifica, Ribeirao Preto, 2006)
Gamma-irradiation (gamma-IR) is extensively used in the treatment of hormone-resistant prostate carcinoma. The objective of the present study was to investigate the effects of Co-60 gamma-IR on the growth, cell cycle arrest ...
Effect of carvedilol on pulse pressure and left ventricular hypertrophy in spontaneously hypertensive rats with adriamycin nephropathy
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2009)
Recent studies indicated pulse pressure as a risk factor for left ventricular hypertrophy, myocardial infarction, congestive heart failure and stroke as well as chronic renal failure progression. The present study examined ...
Effects of treatment with interleukin-1 receptor antagonist on endogenous interleukin-1 levels in normal and irradiated mice
(Acad Sciences Czech Republic, Inst Physiology, Prague 4, 2000)
The in vivo effects of recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) administration on endogenous IL-1 levels in the circulation and conditioned media (CM) from different immunohematopoietic organ/tissues ...
Dietary lipid intake influences the level of cholesterol bound to haemoglobin in human erythrocytes
(Springer Heidelberg, Heidelberg, 2008)
Background Blood cholesterol levels are affected by diet and in particular by the type of fat intake. We originally showed that a significant but variable amount of cholesterol is firmly bound to haemoglobin (Hb) yielding ...
A human origin type II strain of Toxoplasma gondii causing severe encephalitis in mice
(Elsevier Science Bv, Amsterdam, 2006)
Despite its capacity for sexual reproduction and global distribution, Toxoplasma gondii has a highly clonal structure, with the majority of isolates belonging to three distinct clonal types. Congenital toxoplasmosis has ...
Controlled-rate versus uncontrolled-rate freezing as predictors for platelet cryopreservation efficacy
(Wiley, Hoboken, 2006)
BACKGROUND: Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. ...