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Beneficial effect of walnuts on vascular tone is associated with Akt signalling, voltage-dependent calcium channel LTCC and ATP-sensitive potassium channel Kv1.2
(Taylor & Francis Ltd, Abingdon, 2020)
Consumption of walnuts is beneficial for cardiovascular health. To study walnut effects on proteins involved in vascular tone regulation, control and fructose-fed rats were subjected to walnut diet for 6 weeks. In contrast ...
Exosomes and exosome-mimetics as targeted drug carriers: Where we stand and what the future holds?
(Elsevier, 2022)
Exosomes are a sub-group of extracellular vesicles, playing an important part in a cell-cell communication in many physiological and pathological conditions. Their size and competence for transferring material to recipient ...
Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans – Evidence from untargeted mRNA and miRNA studies
(Elsevier, 2022)
Cardiovascular and metabolic disorders present major causes of mortality in the ageing population. Polyphenols present in human diets possess cardiometabolic protective properties, however their underlying molecular ...
The force-velocity relationship obtained during the squat jump exercise is meaningfully influenced by the initial knee angle
(Routledge Journals, Taylor & Francis Ltd, Abingdon, 2020)
This study aimed to compare the magnitude of the force-velocity (F-V) relationship parameters (maximum force [F-0], maximum velocity [V-0], F-V slope, and maximum power [P-max]) between the squat jumps (SJ) performed from ...
Selectivity of polyclonal repertoire of anti‐microbial IgA and its subclasses in saliva and serum in humans
(Wiley-Blackwell, 2022)
Increased interest in microbiota calls for the thorough analysis of antibody reactivity to different microorganisms. As salivary IgA represents the first line of defence against microorganisms contacting mucosal surfaces, ...
Mucoadhesive buccal tablets with propranolol hydrochloride: Formulation development and in vivo performances in experimental essential hypertension
(Elsevier, 2021)
The objective of this study was to formulate extended-release mucoadhesive buccal tablets of propranolol hydrochloride in order to provide a prolonged absorption of propranolol hydrochloride from the buccal mucosa and to ...
Characterization of personal solar ultraviolet radiation exposure using detrended fluctuation analysis
(Academic Press Inc Elsevier Science, San Diego, 2020)
Studies of personal solar ultraviolet radiation (pUVR) exposure are important to identify populations at-risk of excess and insufficient exposure given the negative and positive health impacts, respectively, of time spent ...
Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease
(Royal Soc Chemistry, Cambridge, 2020)
Flavanol intake positively influences several cardiometabolic risk factors in humans. However, the specific molecular mechanisms of action of flavanols, in terms of gene regulation, in the cell types relevant to cardiometabolic ...
Fructose-rich diet and walnut supplementation differently regulate rat hypothalamic and hippocampal glucose transporters expression
(Wiley, 2021)
BACKGROUND: Nutritional modulations may be considered a strategy to protect mental health. Neuronal homeostasis is highly dependent on the availability of glucose, which represents the primary energy source for the brain. ...