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Urokinase Type Plasminogen Activator and the Molecular Mechanisms of its Regulation in Cancer
(Bentham Science Publ Ltd, Sharjah, 2017)
Background: Urokinase type plasminogen activator (uPA) is a 53-kDa serine protease initially synthesized as a catalytically inactive single chain polypeptide. Inactive-uPA is subject to proteolytic cleavage, which results ...
An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling
(Bentham Science Publ Ltd, Sharjah, 2015)
Interleukin-17A (IL-17A) and its receptor (IL-17RA) are prototype members of IL-17 ligand/receptor family firstly identified in CD4(+) T cells, which comprises six ligands (IL-17A to IL-17F) and five receptors (IL-17RA to ...