TY  - JOUR
AU  - Ilić, Nela V.
AU  - Dubljanin-Raspopović, Emilija
AU  - Nedeljković, Una
AU  - Tomanovic-Vujadinović, Sanja
AU  - Milanović, Slađan
AU  - Petronic-Marković, Ivana
AU  - Ilić, Tihomir V.
PY  - 2016
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/711
AB  - Background: A growing body of evidence supports the effectiveness of using transcranial direct current stimulation (tDCS) in patients with chronic hand motor impairment resulting from stroke. Objective: In this study, we investigate and compare the combined effects of anodal tDCS and occupational therapy (OT) to sham stimulation with OT (control) on fine motor skill deficits of chronic stroke patients. Methods: A total of 26 stroke patients (at  gt = 9 months) were randomly assigned to an active treatment or a control group in a double-blinded, sham-controlled, parallel design study. Each group received OT for 45 min/day (10 sessions for 2 weeks). Treatment was preceded by either 20 minutes of 2mA anodal tDCS over ipsilesional M1 or sham tDCS. A modified Jebsen-Taylor Hand Function Test (mJTHFT) was administered as primary outcome measure, and handgrip dynamometer and upper limb Fugl-Meyer (ULFM) assessments were performed as secondary outcomes. The assessment was done at baseline (T0), after the interventions on day 1(T1), day 10 (T2) and day 40 (T3). Results: We observed a statistically significant effect in the tDCS group when the results were compared to the sham group. The mJTHFT times were significantly shorter immediately after treatment and at day 40. The intervention had no effect on handgrip strength or ULFM score. Conclusion: Fine motor skill deficits in chronic stroke survivors can be improved when intensive OT is primed with anodal tDCS over the ipsilesional hemisphere.
PB  - Ios Press, Amsterdam
T2  - Restorative Neurology & Neuroscience
T1  - Effects of anodal tDCS and occupational therapy on fine motor skill deficits in patients with chronic stroke
EP  - 945
IS  - 6
SP  - 935
VL  - 34
DO  - 10.3233/RNN-160668
ER  - 

@article{
author = "Ilić, Nela V. and Dubljanin-Raspopović, Emilija and Nedeljković, Una and Tomanovic-Vujadinović, Sanja and Milanović, Slađan and Petronic-Marković, Ivana and Ilić, Tihomir V.",
year = "2016",
abstract = "Background: A growing body of evidence supports the effectiveness of using transcranial direct current stimulation (tDCS) in patients with chronic hand motor impairment resulting from stroke. Objective: In this study, we investigate and compare the combined effects of anodal tDCS and occupational therapy (OT) to sham stimulation with OT (control) on fine motor skill deficits of chronic stroke patients. Methods: A total of 26 stroke patients (at  gt = 9 months) were randomly assigned to an active treatment or a control group in a double-blinded, sham-controlled, parallel design study. Each group received OT for 45 min/day (10 sessions for 2 weeks). Treatment was preceded by either 20 minutes of 2mA anodal tDCS over ipsilesional M1 or sham tDCS. A modified Jebsen-Taylor Hand Function Test (mJTHFT) was administered as primary outcome measure, and handgrip dynamometer and upper limb Fugl-Meyer (ULFM) assessments were performed as secondary outcomes. The assessment was done at baseline (T0), after the interventions on day 1(T1), day 10 (T2) and day 40 (T3). Results: We observed a statistically significant effect in the tDCS group when the results were compared to the sham group. The mJTHFT times were significantly shorter immediately after treatment and at day 40. The intervention had no effect on handgrip strength or ULFM score. Conclusion: Fine motor skill deficits in chronic stroke survivors can be improved when intensive OT is primed with anodal tDCS over the ipsilesional hemisphere.",
publisher = "Ios Press, Amsterdam",
journal = "Restorative Neurology & Neuroscience",
title = "Effects of anodal tDCS and occupational therapy on fine motor skill deficits in patients with chronic stroke",
pages = "945-935",
number = "6",
volume = "34",
doi = "10.3233/RNN-160668"
}

Ilić, N. V., Dubljanin-Raspopović, E., Nedeljković, U., Tomanovic-Vujadinović, S., Milanović, S., Petronic-Marković, I.,& Ilić, T. V.. (2016). Effects of anodal tDCS and occupational therapy on fine motor skill deficits in patients with chronic stroke. in Restorative Neurology & Neuroscience
Ios Press, Amsterdam., 34(6), 935-945.
https://doi.org/10.3233/RNN-160668

Ilić NV, Dubljanin-Raspopović E, Nedeljković U, Tomanovic-Vujadinović S, Milanović S, Petronic-Marković I, Ilić TV. Effects of anodal tDCS and occupational therapy on fine motor skill deficits in patients with chronic stroke. in Restorative Neurology & Neuroscience. 2016;34(6):935-945.
doi:10.3233/RNN-160668 .

Ilić, Nela V., Dubljanin-Raspopović, Emilija, Nedeljković, Una, Tomanovic-Vujadinović, Sanja, Milanović, Slađan, Petronic-Marković, Ivana, Ilić, Tihomir V., "Effects of anodal tDCS and occupational therapy on fine motor skill deficits in patients with chronic stroke" in Restorative Neurology & Neuroscience, 34, no. 6 (2016):935-945,
https://doi.org/10.3233/RNN-160668 . .