Dietary intake in newly diagnosed lung cancer patients

Abstract

Introduction/Objective Although smoking is the main risk factor for lung cancer (LC), studies have shown that diet could also play an important role. The objective of this study was to analyze dietary intake of newly diagnosed LC patients and to compare with sex- and age-matched healthy controls. Methods Sixty-nine non-treated LC patients (50 male, 19 female, aged 46-80 years), and 70 healthy controls (50 male, 20 female, aged 47-76 years) filled out a validated food frequency questionnaire in the presence of a trained nutritionist. Nutrient intake was calculated using the Serbian Food Composition Database. Results Similar energy intake was reported by both groups. However, the controls had significantly higher intake of total fats, saturated, monounsaturated, and n-3 polyunsaturated fatty acids (PUFAs) and lower intake of carbohydrates and n-6 PUFAs. Patients with LC reported markedly lower intake of milk and dairy products, eggs, seafood, vegetables, and fruits, and higher intake of grains and grain products. Conclusion Patients with LC had significantly different dietary intake of most nutrients compared to healthy participants, suggesting that changes in dietary patterns could contribute to prevention of LC development.

Uvod/Cilj Iako je pušenje vodeći faktor rizika za rak pluća (RP), studije pokazuju da i način ishrane igra važnu ulogu. Cilj ove studije je da se analiza ishrana kod bolesnika sa novodijagnostikovanim RP i da se uporedi sa zdravom populacijom istog pola i godina starosti. Metode Šezdeset devet bolesnika sa novootkrivenim RP (50 muškaraca, 19 žena, starosti 46-80 godina) i 70 zdravih ispitanika (50 muškaraca, 20 žena, starosti 47-76 godina) popunilo je u prisustvu lekara upitnik o učestalosti kon- zumiranja namirnica. Nutritivni unos je računat pomoću Srpske baze podataka o sastavu namirnica. Rezultati Obe grupe su imale sličan unos energije, ali je u kontrolnoj grupi zabeležen veći unos masti, zasićenih, mononezasićenih i n-3 polinezasićenih masnih kiselina (PNMK), a niži unos ugljenih hidrata i n-6 PNMK. Grupa bolesnika je imala značajno niži unos mleka i mlečnih proizvoda, jaja, morskih plodova, voća i povrća, a veći unos žitarica i proizvoda od brašna. Zaključak Bolesnici sa RP imali su značajno drugačiji način ishrane od zdravih ispitanika, što sugeriše da promene u načinu ishrane mogu da doprinesu prevenciji nastanka kancera pluća.