Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration
Само за регистроване кориснике
2018
Аутори
Millan, CarolaVivanco, Juan F.
Benjumeda-Wijnhoven, Isabel M.
Bjelica, Sunčica
Santibanez, Juan F.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In orthopedic medicine, a feasible reconstruction of bone structures remains one of the main challenges both for healthcare and for improvement of patients' quality of life. There is a growing interest in mesenchymal stem cells (MSCs) medical application, due to their multilineage differentiation potential, and tissue engineering integration to improve bone repair and regeneration. In this review we will describe the main characteristics of MSCs, such as osteogenesis, immunomodulation and antibacterial properties, key parameters to consider during bone repair strategies. Moreover, we describe the properties of calciumphosphate (CaP) bioceramics, which demonstrate to be useful tools in combination with MSCs, due to their biocompatibility, osseointegration and osteoconduction for bone repair and regeneration. Also, we overview the main characteristics of dental cavity MSCs, which are promising candidates, in combination with CaP bioceramics, for bone regeneration and tissue engineering. ...The understanding of MSCs biology and their interaction with CaP bioceramics and other biomaterials is critical for orthopedic surgical bone replacement, reconstruction and regeneration, which is an integrative and dynamic medical, scientific and bioengineering field of research and biotechnology.
Кључне речи:
Bioceramics / Bone regeneration / Calcium phosphate / Dental / Mesenchymal stem cells / Tissue engineeringИзвор:
Cell Biology & Translational Medicine, Vol 3: Stem Cells, Bio-Materials & Tissue Engineering, 2018, 1107, 91-112Издавач:
- Springer International Publishing Ag, Cham
Финансирање / пројекти:
- Филогенетски приступ анализи молекуларне еволуције високо варијабилних вируса - коинфекције, интеракција вируса и домаћина (RS-MESTD-Basic Research (BR or ON)-175024)
- Испитивање патогенезе хематолошких малигнитета (RS-MESTD-Basic Research (BR or ON)-175053)
DOI: 10.1007/5584_2018_249
ISSN: 0065-2598
PubMed: 30105601
WoS: 000458010000007
Scopus: 2-s2.0-85057566183
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Millan, Carola AU - Vivanco, Juan F. AU - Benjumeda-Wijnhoven, Isabel M. AU - Bjelica, Sunčica AU - Santibanez, Juan F. PY - 2018 UR - http://rimi.imi.bg.ac.rs/handle/123456789/863 AB - In orthopedic medicine, a feasible reconstruction of bone structures remains one of the main challenges both for healthcare and for improvement of patients' quality of life. There is a growing interest in mesenchymal stem cells (MSCs) medical application, due to their multilineage differentiation potential, and tissue engineering integration to improve bone repair and regeneration. In this review we will describe the main characteristics of MSCs, such as osteogenesis, immunomodulation and antibacterial properties, key parameters to consider during bone repair strategies. Moreover, we describe the properties of calciumphosphate (CaP) bioceramics, which demonstrate to be useful tools in combination with MSCs, due to their biocompatibility, osseointegration and osteoconduction for bone repair and regeneration. Also, we overview the main characteristics of dental cavity MSCs, which are promising candidates, in combination with CaP bioceramics, for bone regeneration and tissue engineering. The understanding of MSCs biology and their interaction with CaP bioceramics and other biomaterials is critical for orthopedic surgical bone replacement, reconstruction and regeneration, which is an integrative and dynamic medical, scientific and bioengineering field of research and biotechnology. PB - Springer International Publishing Ag, Cham T2 - Cell Biology & Translational Medicine, Vol 3: Stem Cells, Bio-Materials & Tissue Engineering T1 - Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration EP - 112 SP - 91 VL - 1107 DO - 10.1007/5584_2018_249 ER -
@article{ author = "Millan, Carola and Vivanco, Juan F. and Benjumeda-Wijnhoven, Isabel M. and Bjelica, Sunčica and Santibanez, Juan F.", year = "2018", abstract = "In orthopedic medicine, a feasible reconstruction of bone structures remains one of the main challenges both for healthcare and for improvement of patients' quality of life. There is a growing interest in mesenchymal stem cells (MSCs) medical application, due to their multilineage differentiation potential, and tissue engineering integration to improve bone repair and regeneration. In this review we will describe the main characteristics of MSCs, such as osteogenesis, immunomodulation and antibacterial properties, key parameters to consider during bone repair strategies. Moreover, we describe the properties of calciumphosphate (CaP) bioceramics, which demonstrate to be useful tools in combination with MSCs, due to their biocompatibility, osseointegration and osteoconduction for bone repair and regeneration. Also, we overview the main characteristics of dental cavity MSCs, which are promising candidates, in combination with CaP bioceramics, for bone regeneration and tissue engineering. The understanding of MSCs biology and their interaction with CaP bioceramics and other biomaterials is critical for orthopedic surgical bone replacement, reconstruction and regeneration, which is an integrative and dynamic medical, scientific and bioengineering field of research and biotechnology.", publisher = "Springer International Publishing Ag, Cham", journal = "Cell Biology & Translational Medicine, Vol 3: Stem Cells, Bio-Materials & Tissue Engineering", title = "Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration", pages = "112-91", volume = "1107", doi = "10.1007/5584_2018_249" }
Millan, C., Vivanco, J. F., Benjumeda-Wijnhoven, I. M., Bjelica, S.,& Santibanez, J. F.. (2018). Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration. in Cell Biology & Translational Medicine, Vol 3: Stem Cells, Bio-Materials & Tissue Engineering Springer International Publishing Ag, Cham., 1107, 91-112. https://doi.org/10.1007/5584_2018_249
Millan C, Vivanco JF, Benjumeda-Wijnhoven IM, Bjelica S, Santibanez JF. Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration. in Cell Biology & Translational Medicine, Vol 3: Stem Cells, Bio-Materials & Tissue Engineering. 2018;1107:91-112. doi:10.1007/5584_2018_249 .
Millan, Carola, Vivanco, Juan F., Benjumeda-Wijnhoven, Isabel M., Bjelica, Sunčica, Santibanez, Juan F., "Mesenchymal Stem Cells and Calcium Phosphate Bioceramics: Implications in Periodontal Bone Regeneration" in Cell Biology & Translational Medicine, Vol 3: Stem Cells, Bio-Materials & Tissue Engineering, 1107 (2018):91-112, https://doi.org/10.1007/5584_2018_249 . .