RIMI - Repository of the Institute for Medical Research
Institute for Medical Research
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   RIMI
  • Institut za medicinska istraživanja
  • Radovi istraživača / Researchers' publications
  • View Item
  •   RIMI
  • Institut za medicinska istraživanja
  • Radovi istraživača / Researchers' publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats

Thumbnail
2017
827.pdf (278.7Kb)
Authors
Zec, Manja M.
Debeljak-Martačić, Jasmina
Ranković, Slavica G.
Pokimica, Biljana Lj.
Tomić, Mirko
Ignjatović, Đurđica
Glibetić, Marija D.
Popović, Tamara B.
Article (Published version)
Metadata
Show full item record
Abstract
A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (1/4-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P lt 0.05) vs. PLB. AMJ increased dihomo-gamma-linoleic acid (DGLA, 20: 3n-6) (P lt 0.05) and decreased arachidonic acid content (AA, 20: 4n-6) (P lt 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P lt 0.05) and plasma (P lt 0.05). Both aronia juice doses elevated the levels of b...eneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P lt 0.001) in cis-vaccenic acid (VA, 18: 1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.

Keywords:
chokeberry / polyphenols / low-density lipoprotein / arachidonic acid / monounsaturated fatty acids
Source:
Acta Veterinaria-Beograd, 2017, 67, 1, 107-120
Publisher:
  • Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Funding / projects:
  • Biological effects, nutritional intake and status of folate and polysaturate fatty acid (PUFA): improvement of nutrition in Serbia (RS-41030)

DOI: 10.1515/acve-2017-0010

ISSN: 0567-8315

WoS: 000401672900010

Scopus: 2-s2.0-85016758039
[ Google Scholar ]
4
4
URI
http://rimi.imi.bg.ac.rs/handle/123456789/830
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
Institut za medicinska istraživanja
TY  - JOUR
AU  - Zec, Manja M.
AU  - Debeljak-Martačić, Jasmina
AU  - Ranković, Slavica G.
AU  - Pokimica, Biljana Lj.
AU  - Tomić, Mirko
AU  - Ignjatović, Đurđica
AU  - Glibetić, Marija D.
AU  - Popović, Tamara B.
PY  - 2017
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/830
AB  - A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (1/4-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P lt 0.05) vs. PLB. AMJ increased dihomo-gamma-linoleic acid (DGLA, 20: 3n-6) (P lt 0.05) and decreased arachidonic acid content (AA, 20: 4n-6) (P lt 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P lt 0.05) and plasma (P lt 0.05). Both aronia juice doses elevated the levels of beneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P lt 0.001) in cis-vaccenic acid (VA, 18: 1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats
EP  - 120
IS  - 1
SP  - 107
VL  - 67
DO  - 10.1515/acve-2017-0010
UR  - conv_4029
ER  - 
@article{
author = "Zec, Manja M. and Debeljak-Martačić, Jasmina and Ranković, Slavica G. and Pokimica, Biljana Lj. and Tomić, Mirko and Ignjatović, Đurđica and Glibetić, Marija D. and Popović, Tamara B.",
year = "2017",
abstract = "A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (1/4-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P lt 0.05) vs. PLB. AMJ increased dihomo-gamma-linoleic acid (DGLA, 20: 3n-6) (P lt 0.05) and decreased arachidonic acid content (AA, 20: 4n-6) (P lt 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P lt 0.05) and plasma (P lt 0.05). Both aronia juice doses elevated the levels of beneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P lt 0.001) in cis-vaccenic acid (VA, 18: 1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats",
pages = "120-107",
number = "1",
volume = "67",
doi = "10.1515/acve-2017-0010",
url = "conv_4029"
}
Zec, M. M., Debeljak-Martačić, J., Ranković, S. G., Pokimica, B. Lj., Tomić, M., Ignjatović, Đ., Glibetić, M. D.,& Popović, T. B.. (2017). Effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(1), 107-120.
https://doi.org/10.1515/acve-2017-0010
conv_4029
Zec MM, Debeljak-Martačić J, Ranković SG, Pokimica BL, Tomić M, Ignjatović Đ, Glibetić MD, Popović TB. Effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats. in Acta Veterinaria-Beograd. 2017;67(1):107-120.
doi:10.1515/acve-2017-0010
conv_4029 .
Zec, Manja M., Debeljak-Martačić, Jasmina, Ranković, Slavica G., Pokimica, Biljana Lj., Tomić, Mirko, Ignjatović, Đurđica, Glibetić, Marija D., Popović, Tamara B., "Effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats" in Acta Veterinaria-Beograd, 67, no. 1 (2017):107-120,
https://doi.org/10.1515/acve-2017-0010 .,
conv_4029 .

DSpace software copyright © 2002-2015  DuraSpace
About RIMI | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceCommunitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About RIMI | Send Feedback

OpenAIRERCUB