Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand
Само за регистроване кориснике
2017
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT score...s increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation.
Кључне речи:
Motor learning / Brain plasticity / Brain stimulation / Neurorehabilitation / Transcranial magnetic stimulation / Theta burst stimulationИзвор:
Clinical Neurophysiology, 2017, 128, 5, 814-822Издавач:
- Elsevier Ireland Ltd, Clare
Финансирање / пројекти:
- Неинвазивна модулација кортикалне ексцитабилности и пластицитета - Развој метода неинвазивне неуромодулације централног нервног система у испитивања физиолошких механизама, дијагностици и терапији (RS-MESTD-Basic Research (BR or ON)-175012)
DOI: 10.1016/j.clinph.2017.02.020
ISSN: 1388-2457
PubMed: 28340430
WoS: 000402462700017
Scopus: 2-s2.0-85015734050
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Jelić, Milan AU - Filipović, Saša AU - Milanović, Slađan AU - Stevanović, Vuk AU - Konstantinović, Ljubica PY - 2017 UR - http://rimi.imi.bg.ac.rs/handle/123456789/822 AB - Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation. PB - Elsevier Ireland Ltd, Clare T2 - Clinical Neurophysiology T1 - Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand EP - 822 IS - 5 SP - 814 VL - 128 DO - 10.1016/j.clinph.2017.02.020 ER -
@article{ author = "Jelić, Milan and Filipović, Saša and Milanović, Slađan and Stevanović, Vuk and Konstantinović, Ljubica", year = "2017", abstract = "Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation.", publisher = "Elsevier Ireland Ltd, Clare", journal = "Clinical Neurophysiology", title = "Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand", pages = "822-814", number = "5", volume = "128", doi = "10.1016/j.clinph.2017.02.020" }
Jelić, M., Filipović, S., Milanović, S., Stevanović, V.,& Konstantinović, L.. (2017). Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand. in Clinical Neurophysiology Elsevier Ireland Ltd, Clare., 128(5), 814-822. https://doi.org/10.1016/j.clinph.2017.02.020
Jelić M, Filipović S, Milanović S, Stevanović V, Konstantinović L. Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand. in Clinical Neurophysiology. 2017;128(5):814-822. doi:10.1016/j.clinph.2017.02.020 .
Jelić, Milan, Filipović, Saša, Milanović, Slađan, Stevanović, Vuk, Konstantinović, Ljubica, "Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand" in Clinical Neurophysiology, 128, no. 5 (2017):814-822, https://doi.org/10.1016/j.clinph.2017.02.020 . .