Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome
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2017
Authors
Kojadinović, Milica
Arsić, Aleksandra

Debeljak-Martačić, Jasmina

Konić-Ristić, Aleksandra

Kardum, Nevena Đ.

Popović, Tamara B.

Glibetić, Marija D.

Article (Published version)

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BACKGROUNDPomegranate juice is a rich source of polyphenols and is thus a promising dietary antioxidant with numerous health-promoting effects. These include a beneficial impact on cardiovascular health that could be partly attributed to the effects of polyphenols on lipid metabolism. The aim of this study was to investigate whether consumption of pomegranate juice for 6 weeks could modify lipid peroxidation and phospholipid fatty acid composition of plasma and erythrocytes in subjects with metabolic syndrome. Twenty-three women, aged 40-60 years, were enrolled and randomly assigned into two groups: the intervention group, in which each participant consumed 300 mL of juice per day for 6 weeks; and a control group. RESULTSA statistically significant decrease in the relative amount of arachidonic acid (P lt 0.05) and an increase in the relative amount of saturated fatty acids (P lt 0.05) were observed in the intervention group at the end of the consumption period. In addition, pomegr...anate juice significantly increased the relative amount of total mono-unsaturated fatty acids (P lt 0.05), and significantly decreased the levels of thiobarbituric acid reactive substances in erythrocytes (P lt 0.05). The status of blood lipids and the values for blood pressure were not changed during the study. CONCLUSIONThe results obtained indicate a positive impact of the consumption of pomegranate juice on lipid peroxidation and fatty acid status in subjects with metabolic syndrome and suggest potential anti-inflammatory and cardio-protective effects.
Keywords:
metabolic syndrome / pomegranate juice / fatty acid / arachidonic acid / lipid peroxidationSource:
Journal of the Science of Food & Agriculture, 2017, 97, 6, 1798-1804Publisher:
- Wiley, Hoboken
Funding / projects:
DOI: 10.1002/jsfa.7977
ISSN: 0022-5142
PubMed: 27476699
WoS: 000397575200016
Scopus: 2-s2.0-85015160939
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Institut za medicinska istraživanjaTY - JOUR AU - Kojadinović, Milica AU - Arsić, Aleksandra AU - Debeljak-Martačić, Jasmina AU - Konić-Ristić, Aleksandra AU - Kardum, Nevena Đ. AU - Popović, Tamara B. AU - Glibetić, Marija D. PY - 2017 UR - http://rimi.imi.bg.ac.rs/handle/123456789/798 AB - BACKGROUNDPomegranate juice is a rich source of polyphenols and is thus a promising dietary antioxidant with numerous health-promoting effects. These include a beneficial impact on cardiovascular health that could be partly attributed to the effects of polyphenols on lipid metabolism. The aim of this study was to investigate whether consumption of pomegranate juice for 6 weeks could modify lipid peroxidation and phospholipid fatty acid composition of plasma and erythrocytes in subjects with metabolic syndrome. Twenty-three women, aged 40-60 years, were enrolled and randomly assigned into two groups: the intervention group, in which each participant consumed 300 mL of juice per day for 6 weeks; and a control group. RESULTSA statistically significant decrease in the relative amount of arachidonic acid (P lt 0.05) and an increase in the relative amount of saturated fatty acids (P lt 0.05) were observed in the intervention group at the end of the consumption period. In addition, pomegranate juice significantly increased the relative amount of total mono-unsaturated fatty acids (P lt 0.05), and significantly decreased the levels of thiobarbituric acid reactive substances in erythrocytes (P lt 0.05). The status of blood lipids and the values for blood pressure were not changed during the study. CONCLUSIONThe results obtained indicate a positive impact of the consumption of pomegranate juice on lipid peroxidation and fatty acid status in subjects with metabolic syndrome and suggest potential anti-inflammatory and cardio-protective effects. PB - Wiley, Hoboken T2 - Journal of the Science of Food & Agriculture T1 - Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome EP - 1804 IS - 6 SP - 1798 VL - 97 DO - 10.1002/jsfa.7977 UR - conv_3993 ER -
@article{ author = "Kojadinović, Milica and Arsić, Aleksandra and Debeljak-Martačić, Jasmina and Konić-Ristić, Aleksandra and Kardum, Nevena Đ. and Popović, Tamara B. and Glibetić, Marija D.", year = "2017", abstract = "BACKGROUNDPomegranate juice is a rich source of polyphenols and is thus a promising dietary antioxidant with numerous health-promoting effects. These include a beneficial impact on cardiovascular health that could be partly attributed to the effects of polyphenols on lipid metabolism. The aim of this study was to investigate whether consumption of pomegranate juice for 6 weeks could modify lipid peroxidation and phospholipid fatty acid composition of plasma and erythrocytes in subjects with metabolic syndrome. Twenty-three women, aged 40-60 years, were enrolled and randomly assigned into two groups: the intervention group, in which each participant consumed 300 mL of juice per day for 6 weeks; and a control group. RESULTSA statistically significant decrease in the relative amount of arachidonic acid (P lt 0.05) and an increase in the relative amount of saturated fatty acids (P lt 0.05) were observed in the intervention group at the end of the consumption period. In addition, pomegranate juice significantly increased the relative amount of total mono-unsaturated fatty acids (P lt 0.05), and significantly decreased the levels of thiobarbituric acid reactive substances in erythrocytes (P lt 0.05). The status of blood lipids and the values for blood pressure were not changed during the study. CONCLUSIONThe results obtained indicate a positive impact of the consumption of pomegranate juice on lipid peroxidation and fatty acid status in subjects with metabolic syndrome and suggest potential anti-inflammatory and cardio-protective effects.", publisher = "Wiley, Hoboken", journal = "Journal of the Science of Food & Agriculture", title = "Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome", pages = "1804-1798", number = "6", volume = "97", doi = "10.1002/jsfa.7977", url = "conv_3993" }
Kojadinović, M., Arsić, A., Debeljak-Martačić, J., Konić-Ristić, A., Kardum, N. Đ., Popović, T. B.,& Glibetić, M. D.. (2017). Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome. in Journal of the Science of Food & Agriculture Wiley, Hoboken., 97(6), 1798-1804. https://doi.org/10.1002/jsfa.7977 conv_3993
Kojadinović M, Arsić A, Debeljak-Martačić J, Konić-Ristić A, Kardum NĐ, Popović TB, Glibetić MD. Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome. in Journal of the Science of Food & Agriculture. 2017;97(6):1798-1804. doi:10.1002/jsfa.7977 conv_3993 .
Kojadinović, Milica, Arsić, Aleksandra, Debeljak-Martačić, Jasmina, Konić-Ristić, Aleksandra, Kardum, Nevena Đ., Popović, Tamara B., Glibetić, Marija D., "Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome" in Journal of the Science of Food & Agriculture, 97, no. 6 (2017):1798-1804, https://doi.org/10.1002/jsfa.7977 ., conv_3993 .