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dc.creatorKardum, Nevena Đ.
dc.creatorKonić-Ristić, Aleksandra
dc.creatorZec, Manja M.
dc.creatorKojadinović, Milica
dc.creatorPetrović-Oggiano, Gordana P.
dc.creatorZeković, Milica
dc.creatorKroon, Paul A.
dc.creatorGlibetić, Marija
dc.date.accessioned2021-04-20T12:52:39Z
dc.date.available2021-04-20T12:52:39Z
dc.date.issued2017
dc.identifier.issn0963-7486
dc.identifier.urihttp://rimi.imi.bg.ac.rs/handle/123456789/782
dc.description.abstractProducts suitable for use as controls in food interventions designed to demonstrate the role of minor components are largely lacking. In the present study, we aimed to develop a formulation to be used as a placebo in a clinical trial designed to assess the effects of aronia juice polyphenols on platelet function. Three formulations with the same nutrient composition as aronia juice were prepared by mixing various nutrients, artificial colours and flavours with water. The similarity of formulations to aronia juice in terms of taste, colour, smell and texture was assessed by six food panellists. The final placebo was tested for its impact on platelet function, biochemical and anthropometric parameters in a 4-week long study. No significant changes in platelet function, or in several cardiovascular and safety markers were recorded. Formulation suitable for use as a placebo for dietary intervention studies using aronia juice has been developed and demonstrated to be well tolerated in humans.en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.relationEuropean Commission, EU Seventh Framework Programme (FP7) [2312090]
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41030/RS//
dc.relationUK Research & Innovation (UKRI) Biotechnology and Biological Sciences Research Council (BBSRC) [BBS/E/F/00044434, BBS/E/F/00042675]
dc.rightsopenAccess
dc.sourceInternational Journal of Food Sciences & Nutrition
dc.subjectAronia melanocarpaen
dc.subjectanthocyaninsen
dc.subjectplatelet functionen
dc.subjectfunctional fooden
dc.subjectbioactivesen
dc.titleDesign, formulation and sensory evaluation of a polyphenol-rich food placebo: an example of aronia juice for food intervention studiesen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage749
dc.citation.issue6
dc.citation.other68(6): 742-749
dc.citation.rankM22
dc.citation.spage742
dc.citation.volume68
dc.identifier.doi10.1080/09637486.2017.1283682
dc.identifier.pmid28147889
dc.identifier.scopus2-s2.0-85011690499
dc.identifier.wos000404871700011
dc.type.versionpublishedVersion


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