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dc.creatorRadovanović, Saša M.
dc.creatorPerić, Stojan
dc.creatorSavić-Pavićević, D.
dc.creatorDobricić, V.
dc.creatorPesović, J.
dc.creatorKostić, Vladimir S.
dc.creatorRakočević-Stojanović, V.
dc.date.accessioned2021-04-20T12:49:52Z
dc.date.available2021-04-20T12:49:52Z
dc.date.issued2016
dc.identifier.issn0966-6362
dc.identifier.urihttp://rimi.imi.bg.ac.rs/handle/123456789/738
dc.description.abstractObjective: We analyzed temporal and stride characteristics in patients with myotonic dystrophy type 1 (DM1) and type 2 (DM2) while performing dual mental and motor tasks, and investigated correlations between gait parameters and cognitive impairments. Method: Dual-task walking was performed by 37 patients (20 DM1 and 17 DM2) and 48 healthy subjects divided into two groups, age-and gender-matched control group for DM1 (HC1) and age-and gender-matched control group for DM2 (HC2). The subjects performed a basic walking task, dual-motor task, dual-mental task, and combined motor and mental task. Results: DM1 and DM2 patients differed significantly in temporal and stride characteristics compared to HC. Main differences in DM1 were slower gait and shorter stride length, while both DM1 and DM2 patients had a higher degree of variation of the swing time during dual-task gait, a parameter that reflects posture and balance. Impact of the cognitive dual task on gait pattern changes was also observed. Visuospatial ability correlated with gait changes in DM1, while executive functions had stronger influence in DM2 (p lt 0.01). Both patient groups had leg muscle weakness. Conclusion: Gait pattern was impaired in both patient groups concerning temporal and stride characteristics. Dual-task walking paradigm may discover mild initial gait changes and could provide early identification of fall risks and predict possible falls in DM patients.en
dc.publisherElsevier Ireland Ltd, Clare
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175090/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175083/RS//
dc.rightsrestrictedAccess
dc.sourceGait & Posture
dc.subjectMyotonic dystrophy type 1en
dc.subjectMyotonic dystrophy type 2en
dc.subjectCognitive tasken
dc.subjectGAITRite walkway systemen
dc.subjectTemporal and stride parametersen
dc.titleComparison of temporal and stride characteristics in myotonic dystrophies type 1 and 2 during dual-task walkingen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage199
dc.citation.other44: 194-199
dc.citation.rankM21
dc.citation.spage194
dc.citation.volume44
dc.identifier.doi10.1016/j.gaitpost.2015.12.020
dc.identifier.pmid27004657
dc.identifier.scopus2-s2.0-84960928650
dc.identifier.wos000372487000034
dc.type.versionpublishedVersion


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