Characterization of Intor:Swiss albino mice adopted in the Institute of virology, vaccines and sera: Torlak, Belgrade in the early twentieth century
Karakterizacija Intor:Swiss soja albino miševa donetog u Institut za virusologiju, vakcine i serume - Torlak početkom XX veka

2016
Authors
Živković, IrenaRajnpreht, Irena
Minić, Rajna

Mitić, Katarina
Aleksić, Iva
Kadrić, Jasminka
Petrušić, Vladimir
Article (Published version)

Metadata
Show full item recordAbstract
The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production implies using experimental animals, including mice, in in-process controls. The laboratory mice which have been in use in Torlak Institute from the very beginning belong to Swiss albino outbred stock. This stock, which has been in use for more than 80 years contains a large number of mice maintained at all times, was recently named Intor:Swiss. Biological characteristics of Intor:Swiss stock, are presented in this paper for the first time. Taking into account the presented characteristics, the Institute Torlak's Swiss mice are suitable for use in pharmaceutical studies, vaccine development research and basic research, as well as in toxicological studies. The publication of data on the Intor:Swiss mice represents a contribution to the international scientific community, since it offers the possibility for obtaining an additional ...outbred mouse stock for research.
Institut za Virusologiju, vakcine i serume Torlak, osnovan je 1927., a prva vakcina u Institutu proizvedena je 1930. Proizvodnja vakcina je složen proces koji između ostalog podrazumeva i korišćenje eksperimentalnih životinja u kontroli samog procesa. Laboratorijski miševi koji su od samog početka bili u upotrebi u Institutu Torlak, pripadaju Swiss albino outbred soju. Ova kolonija je u upotrebi više od 80 godina i sve vreme se sastoji od velikog broja jedinki što omogućava očuvanje genetske raznolikosti, pa samim tim i outbred karakteristika. Ovi miševi su odnedavno registrovani pod imenom Intor:Swiss, i njihove biološke osobine su u ovom radu prikazane po prvi put. Swiss miševi Instituta Torlak pogodni su za upotrebu u farmaceutskim studijama, za razvojno istraživanje vakcina, osnovna istraživanja i toksikološka ispitivanja. Zbog svega navedenog Intor:Swiss miševi predstavljaju još jedan pogodan animalni model za ispitivanje lekova i vakcina.
Keywords:
laboratory animals / outbtred / Swiss mice / IgG2cSource:
Acta Veterinaria-Beograd, 2016, 66, 3, 279-293Publisher:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Funding / projects:
- Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance (RS-172049)
- Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance (RS-172049)
DOI: 10.1515/acve-2016-0025
ISSN: 0567-8315
WoS: 000384771100001
Scopus: 2-s2.0-84992214351
Collections
Institution/Community
Institut za medicinska istraživanjaTY - JOUR AU - Živković, Irena AU - Rajnpreht, Irena AU - Minić, Rajna AU - Mitić, Katarina AU - Aleksić, Iva AU - Kadrić, Jasminka AU - Petrušić, Vladimir PY - 2016 UR - http://rimi.imi.bg.ac.rs/handle/123456789/733 AB - The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production implies using experimental animals, including mice, in in-process controls. The laboratory mice which have been in use in Torlak Institute from the very beginning belong to Swiss albino outbred stock. This stock, which has been in use for more than 80 years contains a large number of mice maintained at all times, was recently named Intor:Swiss. Biological characteristics of Intor:Swiss stock, are presented in this paper for the first time. Taking into account the presented characteristics, the Institute Torlak's Swiss mice are suitable for use in pharmaceutical studies, vaccine development research and basic research, as well as in toxicological studies. The publication of data on the Intor:Swiss mice represents a contribution to the international scientific community, since it offers the possibility for obtaining an additional outbred mouse stock for research. AB - Institut za Virusologiju, vakcine i serume Torlak, osnovan je 1927., a prva vakcina u Institutu proizvedena je 1930. Proizvodnja vakcina je složen proces koji između ostalog podrazumeva i korišćenje eksperimentalnih životinja u kontroli samog procesa. Laboratorijski miševi koji su od samog početka bili u upotrebi u Institutu Torlak, pripadaju Swiss albino outbred soju. Ova kolonija je u upotrebi više od 80 godina i sve vreme se sastoji od velikog broja jedinki što omogućava očuvanje genetske raznolikosti, pa samim tim i outbred karakteristika. Ovi miševi su odnedavno registrovani pod imenom Intor:Swiss, i njihove biološke osobine su u ovom radu prikazane po prvi put. Swiss miševi Instituta Torlak pogodni su za upotrebu u farmaceutskim studijama, za razvojno istraživanje vakcina, osnovna istraživanja i toksikološka ispitivanja. Zbog svega navedenog Intor:Swiss miševi predstavljaju još jedan pogodan animalni model za ispitivanje lekova i vakcina. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta Veterinaria-Beograd T1 - Characterization of Intor:Swiss albino mice adopted in the Institute of virology, vaccines and sera: Torlak, Belgrade in the early twentieth century T1 - Karakterizacija Intor:Swiss soja albino miševa donetog u Institut za virusologiju, vakcine i serume - Torlak početkom XX veka EP - 293 IS - 3 SP - 279 VL - 66 DO - 10.1515/acve-2016-0025 UR - conv_3685 ER -
@article{ author = "Živković, Irena and Rajnpreht, Irena and Minić, Rajna and Mitić, Katarina and Aleksić, Iva and Kadrić, Jasminka and Petrušić, Vladimir", year = "2016", abstract = "The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production implies using experimental animals, including mice, in in-process controls. The laboratory mice which have been in use in Torlak Institute from the very beginning belong to Swiss albino outbred stock. This stock, which has been in use for more than 80 years contains a large number of mice maintained at all times, was recently named Intor:Swiss. Biological characteristics of Intor:Swiss stock, are presented in this paper for the first time. Taking into account the presented characteristics, the Institute Torlak's Swiss mice are suitable for use in pharmaceutical studies, vaccine development research and basic research, as well as in toxicological studies. The publication of data on the Intor:Swiss mice represents a contribution to the international scientific community, since it offers the possibility for obtaining an additional outbred mouse stock for research., Institut za Virusologiju, vakcine i serume Torlak, osnovan je 1927., a prva vakcina u Institutu proizvedena je 1930. Proizvodnja vakcina je složen proces koji između ostalog podrazumeva i korišćenje eksperimentalnih životinja u kontroli samog procesa. Laboratorijski miševi koji su od samog početka bili u upotrebi u Institutu Torlak, pripadaju Swiss albino outbred soju. Ova kolonija je u upotrebi više od 80 godina i sve vreme se sastoji od velikog broja jedinki što omogućava očuvanje genetske raznolikosti, pa samim tim i outbred karakteristika. Ovi miševi su odnedavno registrovani pod imenom Intor:Swiss, i njihove biološke osobine su u ovom radu prikazane po prvi put. Swiss miševi Instituta Torlak pogodni su za upotrebu u farmaceutskim studijama, za razvojno istraživanje vakcina, osnovna istraživanja i toksikološka ispitivanja. Zbog svega navedenog Intor:Swiss miševi predstavljaju još jedan pogodan animalni model za ispitivanje lekova i vakcina.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta Veterinaria-Beograd", title = "Characterization of Intor:Swiss albino mice adopted in the Institute of virology, vaccines and sera: Torlak, Belgrade in the early twentieth century, Karakterizacija Intor:Swiss soja albino miševa donetog u Institut za virusologiju, vakcine i serume - Torlak početkom XX veka", pages = "293-279", number = "3", volume = "66", doi = "10.1515/acve-2016-0025", url = "conv_3685" }
Živković, I., Rajnpreht, I., Minić, R., Mitić, K., Aleksić, I., Kadrić, J.,& Petrušić, V.. (2016). Characterization of Intor:Swiss albino mice adopted in the Institute of virology, vaccines and sera: Torlak, Belgrade in the early twentieth century. in Acta Veterinaria-Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(3), 279-293. https://doi.org/10.1515/acve-2016-0025 conv_3685
Živković I, Rajnpreht I, Minić R, Mitić K, Aleksić I, Kadrić J, Petrušić V. Characterization of Intor:Swiss albino mice adopted in the Institute of virology, vaccines and sera: Torlak, Belgrade in the early twentieth century. in Acta Veterinaria-Beograd. 2016;66(3):279-293. doi:10.1515/acve-2016-0025 conv_3685 .
Živković, Irena, Rajnpreht, Irena, Minić, Rajna, Mitić, Katarina, Aleksić, Iva, Kadrić, Jasminka, Petrušić, Vladimir, "Characterization of Intor:Swiss albino mice adopted in the Institute of virology, vaccines and sera: Torlak, Belgrade in the early twentieth century" in Acta Veterinaria-Beograd, 66, no. 3 (2016):279-293, https://doi.org/10.1515/acve-2016-0025 ., conv_3685 .