Calcium-Alginate-Inulin Microbeads as Carriers for Aqueous Carqueja Extract
Само за регистроване кориснике
2016
Аутори
Balanc, Bojana
Kalušević, Ana

Drvenica, Ivana

Coelho, Maria Teresa

Đorđević, Verica
Alves, Vitor D.

Sousa, Isabel

Moldao-Martins, Margarida

Rakić, Vesna
Nedović, Viktor

Bugarski, Branko

Чланак у часопису (Објављена верзија)

Метаподаци
Приказ свих података о документуАпстракт
Carqueja (Pterospartum tridentatum) is an endemic species and various bioactive compounds have been identified in its aqueous extract. The aim of this study was to protect the natural antioxidants from the aqueous extract of carqueja by encapsulation in Ca-alginate microbeads and Ca-alginate microbeads containing 10% and 20% (w/v) of inulin. The microbeads produced by electrostatic extrusion technique had an average diameter from 625 mu m to 830 mu m depending on the portion of inulin. The sphericity factor of the hydrogel microbeads had values between 0.014 and 0.026, while freeze dried microbeads had irregular shape, especially those with no excipient. The reduction in microbeads size after freeze drying process (expressed as shrinkage factor) ranged from 0.338 (alginate microbeads with 20% (w/v) of inulin) to 0.523 (plain alginate microbeads). The expressed radical scavenging activity against ABTS and DPPH radicals was found to be between 30% and 40% for encapsulated extract, while ...the fresh extract showed around 47% and 57% of radical scavenging activity for ABTS and DPPH radicals, respectively. The correlation between antioxidant activity and the total phenolic content were found to be positive (in both assay methods, DPPH and ABTS), which indicate that the addition of inulin didn't have influence on antioxidant activity. The presence of inulin reduced stiffness of the hydrogel, and protected bead structure from collapse upon freeze-drying. Alginate-inulin beads are envisaged to be used for delivery of aqueous P. tridentatum extract in functional food products.
Кључне речи:
alginate / electrostatic extrusion / encapsulation / inulin / Pterospartum tridentatumИзвор:
Journal of Food Science, 2016, 81, 1, E65-E75Издавач:
- Wiley, Hoboken
Финансирање / пројекти:
- Развој нових инкапсулационих и ензимских технологија за производњу биокатализатора и биолошки активних компонената хране у циљу повећања њене конкурентности, квалитета и безбедности (RS-46010)
- Fundacao para a Ciencia e a Tecnologia, Portugal
DOI: 10.1111/1750-3841.13167
ISSN: 0022-1147
PubMed: 26613390
WoS: 000368133500010
Scopus: 2-s2.0-84953807473
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Balanc, Bojana AU - Kalušević, Ana AU - Drvenica, Ivana AU - Coelho, Maria Teresa AU - Đorđević, Verica AU - Alves, Vitor D. AU - Sousa, Isabel AU - Moldao-Martins, Margarida AU - Rakić, Vesna AU - Nedović, Viktor AU - Bugarski, Branko PY - 2016 UR - http://rimi.imi.bg.ac.rs/handle/123456789/720 AB - Carqueja (Pterospartum tridentatum) is an endemic species and various bioactive compounds have been identified in its aqueous extract. The aim of this study was to protect the natural antioxidants from the aqueous extract of carqueja by encapsulation in Ca-alginate microbeads and Ca-alginate microbeads containing 10% and 20% (w/v) of inulin. The microbeads produced by electrostatic extrusion technique had an average diameter from 625 mu m to 830 mu m depending on the portion of inulin. The sphericity factor of the hydrogel microbeads had values between 0.014 and 0.026, while freeze dried microbeads had irregular shape, especially those with no excipient. The reduction in microbeads size after freeze drying process (expressed as shrinkage factor) ranged from 0.338 (alginate microbeads with 20% (w/v) of inulin) to 0.523 (plain alginate microbeads). The expressed radical scavenging activity against ABTS and DPPH radicals was found to be between 30% and 40% for encapsulated extract, while the fresh extract showed around 47% and 57% of radical scavenging activity for ABTS and DPPH radicals, respectively. The correlation between antioxidant activity and the total phenolic content were found to be positive (in both assay methods, DPPH and ABTS), which indicate that the addition of inulin didn't have influence on antioxidant activity. The presence of inulin reduced stiffness of the hydrogel, and protected bead structure from collapse upon freeze-drying. Alginate-inulin beads are envisaged to be used for delivery of aqueous P. tridentatum extract in functional food products. PB - Wiley, Hoboken T2 - Journal of Food Science T1 - Calcium-Alginate-Inulin Microbeads as Carriers for Aqueous Carqueja Extract EP - E75 IS - 1 SP - E65 VL - 81 DO - 10.1111/1750-3841.13167 ER -
@article{ author = "Balanc, Bojana and Kalušević, Ana and Drvenica, Ivana and Coelho, Maria Teresa and Đorđević, Verica and Alves, Vitor D. and Sousa, Isabel and Moldao-Martins, Margarida and Rakić, Vesna and Nedović, Viktor and Bugarski, Branko", year = "2016", abstract = "Carqueja (Pterospartum tridentatum) is an endemic species and various bioactive compounds have been identified in its aqueous extract. The aim of this study was to protect the natural antioxidants from the aqueous extract of carqueja by encapsulation in Ca-alginate microbeads and Ca-alginate microbeads containing 10% and 20% (w/v) of inulin. The microbeads produced by electrostatic extrusion technique had an average diameter from 625 mu m to 830 mu m depending on the portion of inulin. The sphericity factor of the hydrogel microbeads had values between 0.014 and 0.026, while freeze dried microbeads had irregular shape, especially those with no excipient. The reduction in microbeads size after freeze drying process (expressed as shrinkage factor) ranged from 0.338 (alginate microbeads with 20% (w/v) of inulin) to 0.523 (plain alginate microbeads). The expressed radical scavenging activity against ABTS and DPPH radicals was found to be between 30% and 40% for encapsulated extract, while the fresh extract showed around 47% and 57% of radical scavenging activity for ABTS and DPPH radicals, respectively. The correlation between antioxidant activity and the total phenolic content were found to be positive (in both assay methods, DPPH and ABTS), which indicate that the addition of inulin didn't have influence on antioxidant activity. The presence of inulin reduced stiffness of the hydrogel, and protected bead structure from collapse upon freeze-drying. Alginate-inulin beads are envisaged to be used for delivery of aqueous P. tridentatum extract in functional food products.", publisher = "Wiley, Hoboken", journal = "Journal of Food Science", title = "Calcium-Alginate-Inulin Microbeads as Carriers for Aqueous Carqueja Extract", pages = "E75-E65", number = "1", volume = "81", doi = "10.1111/1750-3841.13167" }
Balanc, B., Kalušević, A., Drvenica, I., Coelho, M. T., Đorđević, V., Alves, V. D., Sousa, I., Moldao-Martins, M., Rakić, V., Nedović, V.,& Bugarski, B.. (2016). Calcium-Alginate-Inulin Microbeads as Carriers for Aqueous Carqueja Extract. in Journal of Food Science Wiley, Hoboken., 81(1), E65-E75. https://doi.org/10.1111/1750-3841.13167
Balanc B, Kalušević A, Drvenica I, Coelho MT, Đorđević V, Alves VD, Sousa I, Moldao-Martins M, Rakić V, Nedović V, Bugarski B. Calcium-Alginate-Inulin Microbeads as Carriers for Aqueous Carqueja Extract. in Journal of Food Science. 2016;81(1):E65-E75. doi:10.1111/1750-3841.13167 .
Balanc, Bojana, Kalušević, Ana, Drvenica, Ivana, Coelho, Maria Teresa, Đorđević, Verica, Alves, Vitor D., Sousa, Isabel, Moldao-Martins, Margarida, Rakić, Vesna, Nedović, Viktor, Bugarski, Branko, "Calcium-Alginate-Inulin Microbeads as Carriers for Aqueous Carqueja Extract" in Journal of Food Science, 81, no. 1 (2016):E65-E75, https://doi.org/10.1111/1750-3841.13167 . .